-
1
-
-
0033965542
-
Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2
-
Akers IA, Parsons M, Hill B, Hollenberg MD, Sanjar S, Laurent GJ McAnulty RJ. 2000. Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2. Am J Physiol-Lung Cell Mol Physiol 278:L193-L201.
-
(2000)
Am J Physiol-Lung Cell Mol Physiol
, vol.278
-
-
Akers, I.A.1
Parsons, M.2
Hill, B.3
Hollenberg, M.D.4
Sanjar, S.5
Laurent, G.J.6
McAnulty, R.J.7
-
2
-
-
0036191893
-
Protein specificity: Traffic direction required
-
Albert PR, Bobillard L. 2002. protein specificity: Traffic direction required. Cell Signal 14:407-418.
-
(2002)
Cell Signal
, vol.14
, pp. 407-418
-
-
Albert, P.R.1
Bobillard, L.2
-
3
-
-
0030779934
-
Divergence in the G-protein-coupled receptor mitogenic signalling pathway at the level of Raf kinase
-
Apostolidis A, Weiss RH. 1997. Divergence in the G-protein-coupled receptor mitogenic signalling pathway at the level of Raf kinase. Cell Signal 9:439-445.
-
(1997)
Cell Signal
, vol.9
, pp. 439-445
-
-
Apostolidis, A.1
Weiss, R.H.2
-
4
-
-
0025091784
-
Thrombin stimulates inositol phosphate production and intracellular free calcium by a pertussis toxin-insensitive mechanism in osteosarcoma cells
-
Babich M, King KL, Nissenson RA. 1990. Thrombin stimulates inositol phosphate production and intracellular free calcium by a pertussis toxin-insensitive mechanism in osteosarcoma cells. Endocrinology 126:948-954
-
(1990)
Endocrinology
, vol.126
, pp. 948-954
-
-
Babich, M.1
King, K.L.2
Nissenson, R.A.3
-
5
-
-
0028237885
-
G protein coupling to the thrombin receptor in Chinese hamster lung fibroblasts
-
Baffy G, Yang L, Raj S, Manning DR, Williamson JR. 1994. G protein coupling to the thrombin receptor in Chinese hamster lung fibroblasts. J Biol Chem 269:8483-8487.
-
(1994)
J Biol Chem
, vol.269
, pp. 8483-8487
-
-
Baffy, G.1
Yang, L.2
Raj, S.3
Manning, D.R.4
Williamson, J.R.5
-
6
-
-
0021091174
-
Receptor-mediated chemotactic response of a macrophage cell line (J774) to thrombin
-
Bar-Shavit R, Kahn A, Fenton JWD, Wilner GD. 1983. Receptor-mediated chemotactic response of a macrophage cell line (J774) to thrombin. Lab Invest 49:702-707.
-
(1983)
Lab Invest
, vol.49
, pp. 702-707
-
-
Bar-Shavit, R.1
Kahn, A.2
Fenton, J.W.D.3
Wilner, G.D.4
-
7
-
-
0030470167
-
Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases
-
Belham CL, Tate BJ, Scott PH, Pemberton AD, Miller HRP, Wadsworth BM, Gould GW, Plevin R. 1996. Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases. Biochem J 320:939-946.
-
(1996)
Biochem J
, vol.320
, pp. 939-946
-
-
Belham, C.L.1
Tate, B.J.2
Scott, P.H.3
Pemberton, A.D.4
Miller, H.R.P.5
Wadsworth, B.M.6
Gould, G.W.7
Plevin, R.8
-
8
-
-
0030894524
-
Evidence that thrombin-stimulated DNA synthesis in pulmonary arterial fibroblasts involves phosphatidylinositol 3-kinase-dependent p70 ribosomal S6 kinase activation
-
Belham CM, Scott PH, Twomey DP, Gould GW, Wadsworth RM, Plevin R. 1997. Evidence that thrombin-stimulated DNA synthesis in pulmonary arterial fibroblasts involves phosphatidylinositol 3-kinase-dependent p70 ribosomal S6 kinase activation. Cell Signal 9:109-116,
-
(1997)
Cell Signal
, vol.9
, pp. 109-116
-
-
Belham, C.M.1
Scott, P.H.2
Twomey, D.P.3
Gould, G.W.4
Wadsworth, R.M.5
Plevin, R.6
-
9
-
-
0026026907
-
Receptor and G protein-mediated responses to thrombin in HEL cells
-
Brass LF, Manning DB, Williams AG, Woolkalis MJ, Poncz M. 1991. Receptor and G protein-mediated responses to thrombin in HEL cells. J Biol Chem 266:958-965.
-
(1991)
J Biol Chem
, vol.266
, pp. 958-965
-
-
Brass, L.F.1
Manning, D.B.2
Williams, A.G.3
Woolkalis, M.J.4
Poncz, M.5
-
10
-
-
0031577096
-
Activation of NFkappaB is essential but not sufficient to stimulate mitogenesis of vascular smooth muscle cells
-
Bretschneider E, Wittpoth M, Weber AA, Glusa E, Schror K. 1997. Activation of NFkappaB is essential but not sufficient to stimulate mitogenesis of vascular smooth muscle cells. Biochem Biophys Res Comm 235:365-368.
-
(1997)
Biochem Biophys Res Comm
, vol.235
, pp. 365-368
-
-
Bretschneider, E.1
Wittpoth, M.2
Weber, A.A.3
Glusa, E.4
Schror, K.5
-
12
-
-
0016432831
-
Mitogenic activity of blood components. I. Thrombin and prothrombin
-
Chen LB, Buchanan JM. 1970. Mitogenic activity of blood components. I. Thrombin and prothrombin. Proc Natl Acad Sci USA 72:131-135.
-
(1970)
Proc Natl Acad Sci USA
, vol.72
, pp. 131-135
-
-
Chen, L.B.1
Buchanan, J.M.2
-
13
-
-
0029964035
-
Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor
-
Chen Y, Grall D, Salcini AE, Pelicci PG, Pouyssegur J, Van Obberghen-Schilling E. 1996. Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor. EMBO 15:1037-1044.
-
(1996)
EMBO
, vol.15
, pp. 1037-1044
-
-
Chen, Y.1
Grall, D.2
Salcini, A.E.3
Pelicci, P.G.4
Pouyssegur, J.5
Van Obberghen-Schilling, E.6
-
14
-
-
0034161592
-
Protease-activated receptors: Sentries for inflammation?
-
Cocks TM, Moffatt JD. 2000. Protease-activated receptors: sentries for inflammation? Trends Pharmacol Sci 21:103-108.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 103-108
-
-
Cocks, T.M.1
Moffatt, J.D.2
-
15
-
-
0035444796
-
Initiation of' human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2
-
Darmoul D, Marie JC, Devaud H, Gratio V, Laburthe M. 2001. Initiation of' human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2. Br J Cancer 85:772-779.
-
(2001)
Br J Cancer
, vol.85
, pp. 772-779
-
-
Darmoul, D.1
Marie, J.C.2
Devaud, H.3
Gratio, V.4
Laburthe, M.5
-
16
-
-
0030683639
-
Signal characteristics of G protein-transactivated EGF receptor
-
Daub H, Wallasch C, Lankenau A, Herrlich A, Ullrich A. 1997. Signal characteristics of G protein-transactivated EGF receptor. EMBO 16:7032-7044.
-
(1997)
EMBO
, vol.16
, pp. 7032-7044
-
-
Daub, H.1
Wallasch, C.2
Lankenau, A.3
Herrlich, A.4
Ullrich, A.5
-
17
-
-
0034689003
-
beta-Arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
-
DeFea KA, Zalevsky J, Thoma MS, Dery O, Mullins RD, Bunnett NW. 2000, beta-Arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol 148:1267-1281.
-
(2000)
J Cell Biol
, vol.148
, pp. 1267-1281
-
-
DeFea, K.A.1
Zalevsky, J.2
Thoma, M.S.3
Dery, O.4
Mullins, R.D.5
Bunnett, N.W.6
-
18
-
-
0030034469
-
G-protein coupled and tyrosine kinase receptors: Evidence that activation of the insulin-like growth factor I receptor is required for thrombin-induced mitogenesis of rat aortic smooth muscle cells
-
Delafontaine P, Anwar A, Lou H, Ku L. 1996. G-protein coupled and tyrosine kinase receptors: evidence that activation of the insulin-like growth factor I receptor is required for thrombin-induced mitogenesis of rat aortic smooth muscle cells. J Clin Invest 97:139-145.
-
(1996)
J Clin Invest
, vol.97
, pp. 139-145
-
-
Delafontaine, P.1
Anwar, A.2
Lou, H.3
Ku, L.4
-
19
-
-
0037040042
-
Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: Evidence for new autocrine loop
-
Ducroc R, Bontemps C, Marazova K, Devaud H, Darmoul D, Laburthe M. 2002. Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop. Life Sci 70:1359-1367.
-
(2002)
Life Sci
, vol.70
, pp. 1359-1367
-
-
Ducroc, R.1
Bontemps, C.2
Marazova, K.3
Devaud, H.4
Darmoul, D.5
Laburthe, M.6
-
20
-
-
0037247658
-
Essential role for proteinase-activated receptor-2 in arthritis
-
Ferral WR, Lockhart JC, Kelso EB, Dunning L, Plevin R, Meeks SE, Smith AJH, Hunter GD, McLean JS, McGarry F, Ramage R, Jiang L, Kanke T, Kawagoe J. 2003. Essential role for proteinase-activated receptor-2 in arthritis. J Clin Invest 111:35-41.
-
(2003)
J Clin Invest
, vol.111
, pp. 35-41
-
-
Ferral, W.R.1
Lockhart, J.C.2
Kelso, E.B.3
Dunning, L.4
Plevin, R.5
Meeks, S.E.6
Smith, A.J.H.7
Hunter, G.D.8
McLean, J.S.9
McGarry, F.10
Ramage, R.11
Jiang, L.12
Kanke, T.13
Kawagoe, J.14
-
21
-
-
0037069333
-
2, COX2, prostaglandins, and PPARgamma: Possible relevance to human fibrotic disorders
-
2, COX2, prostaglandins, and PPARgamma: Possible relevance to human fibrotic disorders. Proc Natl Acad Sci USA 99:15072-15077.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15072-15077
-
-
Frungieri, M.B.1
Weidinger, S.2
Meineke, V.3
Kohn, F.M.4
Mayerhofer, A.5
-
22
-
-
0036189530
-
Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors
-
Gaca MD, Zhou X, Benyon RC. 2002. Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors. J Hepat 36:362-369.
-
(2002)
J Hepat
, vol.36
, pp. 362-369
-
-
Gaca, M.D.1
Zhou, X.2
Benyon, R.C.3
-
23
-
-
0026782001
-
The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase
-
Hung DT, Wong YH, Vu TK, Coughlin SR. 1992. The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase. J Biol Chem 267:20831-20834.
-
(1992)
J Biol Chem
, vol.267
, pp. 20831-20834
-
-
Hung, D.T.1
Wong, Y.H.2
Vu, T.K.3
Coughlin, S.R.4
-
24
-
-
0042404135
-
Expression of proteinase-activated receptor-2 in human pancreatic cancer: A possible relation to cancer invasion and induction of fibrosis
-
Ikeda O, Egami H, Ishiko T, Ishikawa S, Kamohara H, Hidaka H, Mita S, Ogawa M. 2003. Expression of proteinase-activated receptor-2 in human pancreatic cancer: A possible relation to cancer invasion and induction of fibrosis. Int J Oncol 22:295-300.
-
(2003)
Int J Oncol
, vol.22
, pp. 295-300
-
-
Ikeda, O.1
Egami, H.2
Ishiko, T.3
Ishikawa, S.4
Kamohara, H.5
Hidaka, H.6
Mita, S.7
Ogawa, M.8
-
25
-
-
0030979972
-
Protease-activited receptor 3 is a second thrombin receptor in humans
-
Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, Coughlin SB. 1997. Protease-activited receptor 3 is a second thrombin receptor in humans. Nature 386:502-506.
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
Connolly, A.J.2
Zeng, D.3
Kahn, M.L.4
Zheng, Y.W.5
Timmons, C.6
Tram, T.7
Coughlin, S.B.8
-
26
-
-
0037303494
-
2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas
-
2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas. Cancer 97:703-713.
-
(2003)
Cancer
, vol.97
, pp. 703-713
-
-
Jin, E.1
Fujiwara, M.2
Pan, X.3
Ghazizadeh, M.4
Arai, S.5
Ohald, Y.6
Kajiwara, K.7
Takemura, T.8
Kawanami, O.9
-
27
-
-
0026772506
-
Coordinate, Biphasic activation of p44 mitogen-activated protein-kinase and s6 kinase by growth-factors in hamster fibroblasts: Evidence for thrombin-induced signals different from phosphoinositide turnover and adenylylcyclase inhibition
-
Kahan C, Seuwen K, Meloche S, Pouyssegur J. 1992. Coordinate, Biphasic activation of p44 mitogen-activated protein-kinase and s6 kinase by growth-factors in hamster fibroblasts: evidence for thrombin-induced signals different from phosphoinositide turnover and adenylylcyclase inhibition. J Biol Chem 267:13369-13375.
-
(1992)
J Biol Chem
, vol.267
, pp. 13369-13375
-
-
Kahan, C.1
Seuwen, K.2
Meloche, S.3
Pouyssegur, J.4
-
28
-
-
0035031186
-
Thrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathway
-
Kanda Y, Mizuno K, Kuroki Y, Watanabe Y. 2001. Thrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathway. Br J Pharmacol 132:1657-1664.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1657-1664
-
-
Kanda, Y.1
Mizuno, K.2
Kuroki, Y.3
Watanabe, Y.4
-
29
-
-
0035943658
-
Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes
-
Kanke T, Macfarlane SR, Seatter MJ, Davenport E, Paul A, McKenzie RC, Plevin R. 2001. Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes. J Biol Chem 216:31657-31666.
-
(2001)
J Biol Chem
, vol.216
, pp. 31657-31666
-
-
Kanke, T.1
Macfarlane, S.R.2
Seatter, M.J.3
Davenport, E.4
Paul, A.5
McKenzie, R.C.6
Plevin, R.7
-
30
-
-
0030025078
-
Involvement of pertussis toxin-sensitive and -insensitive G proteins in alpha-thrombin signalling on cultured human vascular smooth muscle cells
-
Kanthou C, Kause SM, Kakkar VV, Benzakour O. 1996. Involvement of pertussis toxin-sensitive and -insensitive G proteins in alpha-thrombin signalling on cultured human vascular smooth muscle cells. Cell Signal 8:59-66.
-
(1996)
Cell Signal
, vol.8
, pp. 59-66
-
-
Kanthou, C.1
Kause, S.M.2
Kakkar, V.V.3
Benzakour, O.4
-
32
-
-
0032695476
-
Modulation by protease-activated receptors of the rat duodenal motility in vitro: Possible mechanisms underlying the evoked contraction and relaxation
-
Kawabata A, Kuroda R, Nishikawa H, Kawai K. 1999. Modulation by protease-activated receptors of the rat duodenal motility in vitro: possible mechanisms underlying the evoked contraction and relaxation. Br J Pharmacol 128:865-872.
-
(1999)
Br J Pharmacol
, vol.128
, pp. 865-872
-
-
Kawabata, A.1
Kuroda, R.2
Nishikawa, H.3
Kawai, K.4
-
33
-
-
0032810950
-
Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation
-
Krymskaya VP, Penn RB, Orsini MJ, Scott PH, Plevin RJ, Walker TB, Eszterhas AJ, Amrani Y, Chilvers ER, Panettieri BA. 1999. Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation. Am J Physiol-Lung Cell Mol Physiol 277:L65-L78.
-
(1999)
Am J Physiol-Lung Cell Mol Physiol
, vol.277
-
-
Krymskaya, V.P.1
Penn, R.B.2
Orsini, M.J.3
Scott, P.H.4
Plevin, R.J.5
Walker, T.B.6
Eszterhas, A.J.7
Amrani, Y.8
Chilvers, E.R.9
Panettieri, B.A.10
-
34
-
-
0036098860
-
Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors
-
Luttrell LM. 2002. Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors. Can J Physiol Pharmacol 80:375-382.
-
(2002)
Can J Physiol Pharmacol
, vol.80
, pp. 375-382
-
-
Luttrell, L.M.1
-
35
-
-
0035019636
-
Proteinase-activated receptors
-
Macfarlane SR, Seatter MJ, Kanke T, Hunter GD, Plevin R. 2001. Proteinase-activated receptors. Pharmacol Rev 53:245-282.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 245-282
-
-
Macfarlane, S.R.1
Seatter, M.J.2
Kanke, T.3
Hunter, G.D.4
Plevin, R.5
-
36
-
-
0029025036
-
The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors
-
Malarkey K, Belham CM, Paul A, Graham A, McLees A, Scott PH, Plevin R. 1995. The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors, Biochem J 309:361-375.
-
(1995)
Biochem J
, vol.309
, pp. 361-375
-
-
Malarkey, K.1
Belham, C.M.2
Paul, A.3
Graham, A.4
McLees, A.5
Scott, P.H.6
Plevin, R.7
-
37
-
-
0034253196
-
Small G-protein networks: Their crosstalk and signal cascades
-
Matozaki T, Nakanishi H, Takai Y. 2000. Small G-protein networks: Their crosstalk and signal cascades. Cell Signal 12:515-524.
-
(2000)
Cell Signal
, vol.12
, pp. 515-524
-
-
Matozaki, T.1
Nakanishi, H.2
Takai, Y.3
-
38
-
-
0034737483
-
The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
-
Maudsley S, Pierce KL, Zamah AM, Miller WE, Ahn S, Daaka Y, Lefkowitz RJ, Luttrell LM. 2000. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J Biol Chem 275:9572-9580.
-
(2000)
J Biol Chem
, vol.275
, pp. 9572-9580
-
-
Maudsley, S.1
Pierce, K.L.2
Zamah, A.M.3
Miller, W.E.4
Ahn, S.5
Daaka, Y.6
Lefkowitz, R.J.7
Luttrell, L.M.8
-
39
-
-
0041919984
-
Thrombin stimulation of VCAM-1 in endothelial cells is mediated by PKC-delta-NFkappa B and PKC-zeta-GATA signalling pathways
-
Minami T, Abid MR, Zhang J, King G, Kodama T, Aird WC. 2002. Thrombin stimulation of VCAM-1 in endothelial cells is mediated by PKC-delta-NFkappa B and PKC-zeta-GATA signalling pathways. J Biol Chem 275:6976-6984.
-
(2002)
J Biol Chem
, vol.275
, pp. 6976-6984
-
-
Minami, T.1
Abid, M.R.2
Zhang, J.3
King, G.4
Kodama, T.5
Aird, W.C.6
-
40
-
-
0030003829
-
2) mediates mitogenic responses in human vascular endothelial cells: Molecular characterization and evidence for functional coupling to the thrombin receptor
-
2) mediates mitogenic responses in human vascular endothelial cells: molecular characterization and evidence for functional coupling to the thrombin receptor. J Clin Invest 97:1705-1714.
-
(1996)
J Clin Invest
, vol.97
, pp. 1705-1714
-
-
Mirza, H.1
Yatsula, V.2
Bahou, W.F.3
-
41
-
-
0025667153
-
Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets
-
Mitchell CA, Jefferson AB, Bejeck BE, Brugge JS, Deuel TF, Majerus PW. 1990. Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets. Proc Nat Acad Sci USA 87:9396-9400.
-
(1990)
Proc Nat Acad Sci USA
, vol.87
, pp. 9396-9400
-
-
Mitchell, C.A.1
Jefferson, A.B.2
Bejeck, B.E.3
Brugge, J.S.4
Deuel, T.F.5
Majerus, P.W.6
-
42
-
-
0036896113
-
Signal transduction pathways involved in the mechanical responses to protease-activated receptors in rat colon
-
Mule F, Baffi MC, Falzone M, Cerra MC. 2002. Signal transduction pathways involved in the mechanical responses to protease-activated receptors in rat colon. J Exp Ther 303:1265-1272.
-
(2002)
J Exp Ther
, vol.303
, pp. 1265-1272
-
-
Mule, F.1
Baffi, M.C.2
Falzone, M.3
Cerra, M.C.4
-
43
-
-
0028171461
-
Involvement of NF-kappa B activation in thrombin-induced human vascular smooth muscle cell proliferation
-
Nakajima T, Kitajima I, Shin H, Takasaki I, Shigeta K, Abeyama K, Yamashita Y, Tokioka T, Soejima Y, Maruyama I. 1994. Involvement of NF-kappa B activation in thrombin-induced human vascular smooth muscle cell proliferation. Biochem Biophys Res Commun 204:950-958.
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 950-958
-
-
Nakajima, T.1
Kitajima, I.2
Shin, H.3
Takasaki, I.4
Shigeta, K.5
Abeyama, K.6
Yamashita, Y.7
Tokioka, T.8
Soejima, Y.9
Maruyama, I.10
-
44
-
-
0034611727
-
PAR3 is a cofactor for PAR4 activation by thrombin
-
Nakanishi-Matsui M, Zheng YW, Sulciner DJ, Weiss EJ, Ludeman MJ, Coughlin SR. 2000. PAR3 is a cofactor for PAR4 activation by thrombin. Nature 404:609-613.
-
(2000)
Nature
, vol.404
, pp. 609-613
-
-
Nakanishi-Matsui, M.1
Zheng, Y.W.2
Sulciner, D.J.3
Weiss, E.J.4
Ludeman, M.J.5
Coughlin, S.R.6
-
46
-
-
0036211981
-
1 receptors in cellular invasion
-
1 receptors in cellular invasion. FASEB J 16:565-576.
-
(2002)
FASEB J
, vol.16
, pp. 565-576
-
-
Nguyen, Q.D.1
Faivre, S.2
Bruyneel, E.3
Rivat, C.4
Seto, M.5
Endo, T.6
Mareel, M.7
Emami, S.8
Gespach, C.9
-
47
-
-
0029113121
-
Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
-
Nystedt S, Emilsson K, Larsson A K, Strombeck B, Sundelin J. 1995. Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur J Biochem 232:84-89.
-
(1995)
Eur J Biochem
, vol.232
, pp. 84-89
-
-
Nystedt, S.1
Emilsson, K.2
Larsson, A.K.3
Strombeck, B.4
Sundelin, J.5
-
48
-
-
0028179510
-
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets
-
Offermanns S, Laugwitz KL, Spicher K, Schultz G. 1994. G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proc Nat Acad Sci 91:504-508.
-
(1994)
Proc Nat Acad Sci
, vol.91
, pp. 504-508
-
-
Offermanns, S.1
Laugwitz, K.L.2
Spicher, K.3
Schultz, G.4
-
49
-
-
0030605209
-
Direct evidence for two distinct G proteins coupling with thrombin receptors in human neuroblastoma SH-EP cells
-
Ogino Y, Tanaka K, Shimizu N. 1996. Direct evidence for two distinct G proteins coupling with thrombin receptors in human neuroblastoma SH-EP cells. Eur J Pharmacol 316:105-109.
-
(1996)
Eur J Pharmacol
, vol.316
, pp. 105-109
-
-
Ogino, Y.1
Tanaka, K.2
Shimizu, N.3
-
50
-
-
0027170451
-
Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation
-
Pages G, Lenormand P, L'Allemain G, Chambard JC, Meloche S, Pouyssegur J. 1993. Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sci USA 90:8319-8323
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8319-8323
-
-
Pages, G.1
Lenormand, P.2
L'Allemain, G.3
Chambard, J.C.4
Meloche, S.5
Pouyssegur, J.6
-
51
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
-
Pearson G, Robinson F, Gibson TB, Xu B-E, Karandikar M, Berman K, Cobb MH. 2001. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22:53-183.
-
(2001)
Endocr Rev
, vol.22
, pp. 53-183
-
-
Pearson, G.1
Robinson, F.2
Gibson, T.B.3
Xu, B.-E.4
Karandikar, M.5
Berman, K.6
Cobb, M.H.7
-
53
-
-
0034717192
-
Signaling properties and functions of two distinct cardiomyocyte protease-activated receptors
-
Sabri A, Muske G, Zhang HL, Pak E, Darrow A, Andrade-Gordon P, Steinberg SF. 2000. Signaling properties and functions of two distinct cardiomyocyte protease-activated receptors. Circ Res 86:1054-1061.
-
(2000)
Circ Res
, vol.86
, pp. 1054-1061
-
-
Sabri, A.1
Muske, G.2
Zhang, H.L.3
Pak, E.4
Darrow, A.5
Andrade-Gordon, P.6
Steinberg, S.F.7
-
55
-
-
0037900130
-
Mechanisms of protease-activated receptor-4 actions in cardiomyocytes: Role of Src tyrosine kinase
-
Sabri A, Guo J, Elouardighi H, Darrow AL, Andrade-Gordon P, Steinberg SF. 2003. Mechanisms of protease-activated receptor-4 actions in cardiomyocytes: role of Src tyrosine kinase. J Biol Chem 278:11714-11720.
-
(2003)
J Biol Chem
, vol.278
, pp. 11714-11720
-
-
Sabri, A.1
Guo, J.2
Elouardighi, H.3
Darrow, A.L.4
Andrade-Gordon, P.5
Steinberg, S.F.6
-
56
-
-
0035817822
-
Role of thrombin signalling in platelets in haemostasis and thrombosis
-
Sambrano GR, Weiss EJ, Zheng YW, Huang W, Coughlin SR. 2001. Role of thrombin signalling in platelets in haemostasis and thrombosis. Nature 413:6851:74-78.
-
(2001)
Nature
, vol.6851
, pp. 74-78
-
-
Sambrano, G.R.1
Weiss, E.J.2
Zheng, Y.W.3
Huang, W.4
Coughlin, S.R.5
-
57
-
-
0029021942
-
Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes
-
Santulli RJ, Derian CK, Darrow AL, Tomko KA, Eckardt AJ, Seiberg M, Scarborough RM, Andrade-Gordon P. 1995. Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes. Proc Natl Acad Sci 92:9151-9155.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 9151-9155
-
-
Santulli, R.J.1
Derian, C.K.2
Darrow, A.L.3
Tomko, K.A.4
Eckardt, A.J.5
Seiberg, M.6
Scarborough, R.M.7
Andrade-Gordon, P.8
-
58
-
-
9844231500
-
Endogenous trypsin receptors in Xenopus oocytes: Linkage to internal calcium stores
-
Schultheiss M, Neumcke B, Richter HP. 1997. Endogenous trypsin receptors in Xenopus oocytes: linkage to internal calcium stores. Cell Mol Life Sci 53:842-849.
-
(1997)
Cell Mol Life Sci
, vol.53
, pp. 842-849
-
-
Schultheiss, M.1
Neumcke, B.2
Richter, H.P.3
-
59
-
-
0034723344
-
1 thrombin receptor-G protein interactions: Separation of binding and coupling determinants in the G alpha subunit
-
1 thrombin receptor-G protein interactions: separation of binding and coupling determinants in the G alpha subunit. J Biol Chem 275:2627-2635.
-
(2000)
J Biol Chem
, vol.275
, pp. 2627-2635
-
-
Swift, S.1
Sheridan, P.J.2
Covic, L.3
Kuliopulos, A.4
-
60
-
-
0036721731
-
Tryptase activates the mitogen-activated protein kinase/activator protein-1 pathway in human peripheral blood eosinophils, causing cytokine production and release
-
Temkin V, Kantor B, Weg V, Hartman ML, Levi-Schaffer F. 2002. Tryptase activates the mitogen-activated protein kinase/activator protein-1 pathway in human peripheral blood eosinophils, causing cytokine production and release. J Immunol 169:2662-2669.
-
(2002)
J Immunol
, vol.169
, pp. 2662-2669
-
-
Temkin, V.1
Kantor, B.2
Weg, V.3
Hartman, M.L.4
Levi-Schaffer, F.5
-
62
-
-
0027411213
-
Pertussis toxin-sensitive activation of P21(Ras) by G-protein-coupled receptor agonists in fibroblasts
-
Van Corven EJ, Hordijk PL, Medema RH, Bos JL, Moolenaar WH. 1993. Pertussis toxin-sensitive activation of P21(Ras) by G-protein-coupled receptor agonists in fibroblasts. Proc Natl Acad Sci USA 90:1257-1261.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1257-1261
-
-
Van Corven, E.J.1
Hordijk, P.L.2
Medema, R.H.3
Bos, J.L.4
Moolenaar, W.H.5
-
63
-
-
0032708759
-
Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo
-
Vergnolle N. 1999. Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo. J Immunol 163:5064-5069.
-
(1999)
J Immunol
, vol.163
, pp. 5064-5069
-
-
Vergnolle, N.1
-
64
-
-
0034055571
-
Review article: Proteinase-activated receptors: Novel signals for gastrointestinal pathophysiology
-
Vergnolle N. 2000. Review article: proteinase-activated receptors: novel signals for gastrointestinal pathophysiology. Aliment Pharmacol Ther 14:257-266.
-
(2000)
Aliment Pharmacol Ther
, vol.14
, pp. 257-266
-
-
Vergnolle, N.1
-
66
-
-
0035282747
-
Protease-activated receptors in inflammation, neuronal signaling and pain
-
Vergnolle N, Wallace JL, Bunnett NW, Hollenberg MD. 2001. Protease-activated receptors in inflammation, neuronal signaling and pain. Trends Pharmacol Sci 22:146-152.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 146-152
-
-
Vergnolle, N.1
Wallace, J.L.2
Bunnett, N.W.3
Hollenberg, M.D.4
-
67
-
-
0027082666
-
Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis
-
Vouret-Craviari V, Van Obberghen-Schilling E, Rasmussen UB, Pavirani A, Lecocq JP, Pouyssegur J. 1992. Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis. Mol Biol Cell 3:95-102.
-
(1992)
Mol Biol Cell
, vol.3
, pp. 95-102
-
-
Vouret-Craviari, V.1
Van Obberghen-Schilling, E.2
Rasmussen, U.B.3
Pavirani, A.4
Lecocq, J.P.5
Pouyssegur, J.6
-
68
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu TK, Hung DT, Wheaton VI, Coughlin S. 1991. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64:1057-1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.4
-
69
-
-
0030893530
-
Thrombin and trypsin induce granulocyte-macrophage colony-stimulating factor and interleukin-6 gene expression in cultured normal human keratinocytes
-
Wakita H, Furukawa F, Takigawa M. 1997. Thrombin and trypsin induce granulocyte-macrophage colony-stimulating factor and interleukin-6 gene expression in cultured normal human keratinocytes. Proc Assoc Am Physicians 109:190-207.
-
(1997)
Proc Assoc Am Physicians
, vol.109
, pp. 190-207
-
-
Wakita, H.1
Furukawa, F.2
Takigawa, M.3
-
70
-
-
0032407674
-
Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: Role in mediating airway smooth muscle proliferation
-
Walker TR, Moore SM, Lawson MF, Panettieri RA Jr, Chilvers ER. 1998. Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation. Mol Pharmacol 54:1007-1015.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 1007-1015
-
-
Walker, T.R.1
Moore, S.M.2
Lawson, M.F.3
Panettieri R.A., Jr.4
Chilvers, E.R.5
-
71
-
-
0036006726
-
Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling
-
Wang H, Ubl JJ, Reiser G. 2002. Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling. Glia 37:53-63.
-
(2002)
Glia
, vol.37
, pp. 53-63
-
-
Wang, H.1
Ubl, J.J.2
Reiser, G.3
-
72
-
-
0027412695
-
The mitogenic effect of thrombin in vascular smooth muscle cells is largely due to basic fibroblast growth factor
-
Weiss RH, Maduri M. 1993. The mitogenic effect of thrombin in vascular smooth muscle cells is largely due to basic fibroblast growth factor. J Biol Chem 268:5724-5727.
-
(1993)
J Biol Chem
, vol.268
, pp. 5724-5727
-
-
Weiss, R.H.1
Maduri, M.2
-
73
-
-
0030936370
-
Protein-tyrosine phosphatase SHP2 is positively linked to proteinase-activated receptor 2-mediated mitogenic pathway
-
Yu Z, Ahmad S, Schwartz JL, Banville D, Shen SH. 1997. Protein-tyrosine phosphatase SHP2 is positively linked to proteinase-activated receptor 2-mediated mitogenic pathway. J Biol Chem 272:7519-7524.
-
(1997)
J Biol Chem
, vol.272
, pp. 7519-7524
-
-
Yu, Z.1
Ahmad, S.2
Schwartz, J.L.3
Banville, D.4
Shen, S.H.5
|