Cadmium-induced non-apoptotic cell death mediated by oxidative stress under the condition of sulfhydryl deficiency

Toxicology Letters

Volumn 144, Issue 3, 2003, Pages 325-336

  Kim, Sang Chan ^a,b   Cho, Min Kyung ^a   Kim, Sang Geon ^a  

^a Seoul National University   (South Korea)

^b Kyungsan University   (South Korea)

Author keywords

Apoptosis; Cadmium; Cytotoxicity; PARP; Sulfhydryl deficiency

Indexed keywords

BUTHIONINE SULFOXIMINE; CADMIUM; CASPASE 9; CYTOCHROME C; GLUTATHIONE; MITOCHONDRIAL PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAD; PROTEIN BCL XL;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INDUCTION; ENZYME RELEASE; FLOW CYTOMETRY; LIVER CELL; LIVER CELL DAMAGE; LIVER TOXICITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; TOXICOKINETICS;

EID: 0042133151     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(03)00233-9     Document Type: Article

References (22)

1. Cook S.A., Sugden P.H., Clerk A. Regulation of Bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. Circ. Res. 85:1999;940-949.
2. Dusre L., Mimnaugh E.G., Myers C.E., Sinha B.K. Potentiation of doxorubicin cytotoxicity by buthionine sulfoximine in multidrug-resistant human breast tumor cells. Cancer Res. 49:1989;511-515.
3. Falck F.Y. Jr, Fine L.J., Smith R.G., McClatchey K.D., Annesley T., England B., Schork A.M. Occupational cadmium exposure and renal status. Am. J. Ind. Med. 4:1983;541-549.
4. Figueiredo-Pereira M.E., Yakushin S., Cohen G. Disruption of the intracellular sulfhydryl homeostasis by cadmium-induced oxidative stress leads to protein thiolation and ubiquitination in neuronal cells. J. Biol. Chem. 273:1998;12703-12709.
5. Galan A., Troyano A., Vilaboa N.E., Fernandez C., de Blas E., Aller P. Modulation of the stress response during apoptosis and necrosis induction in cadmium-treated U-937 human promonocytic cells. Biochim. Biophys. Acta. 1538:2001;38-46.
6. Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine. 1999;129-134 Oxford University Press, New York.
7. Kang K.W., Ryu J.H., Kim S.G. The essential role of phosphatidylinositol 3-kinase and of p38 mitogen-activated protein kinase activation in the antioxidant response element-mediated rGSTA2 induction by decreased glutathione in H4IIE hepatoma cells. Mol. Pharmacol. 58:2000;1017-1025.
8. Kang K.W., Novak R.F., Lee C.H., Kim S.G. Induction of microsomal epoxide hydrolase by sulfur amino acid deprivation via the pathway of c-Jun N-terminal kinase and its extracellular exposure during cell death. Free Radic. Biol. Med. 32:2002;1017-1032.
9. Klaassen C.D. Casarett and Doull's Toxociology. 2001;822-826 McGraw-Hill Medical Publishing Division, New York.
10. Klaassen C.D., Liu J. Role of metallothionein in cadmium-induced hepatotoxicity and nephrotoxicity. Drug Metab. Rev. 29:1997;79-102.
11. Kondoh M., Araragi S., Sato K., Higashimoto M., Takiguchi M., Sato M. Cadmium induces apoptosis partly via caspase-9 activation in HL-60 cells. Toxicology. 170:2002;111-117.
12. Mehmet H. Caspases find a new place to hide. Nature. 403:2000;29-30.
13. Nomura M., Shimizu S., Sugiyama T., Narita M., Ito T., Matsuda H., Tsujimoto Y. 14-3-3 interacts directly with and negatively regulates pro-apoptotic Bax. J. Biol. Chem. 278:2003;2058-2065.
14. Raffray M., Cohen G.M. Apoptosis and necrosis in toxicology: a continuum or distinct modes of cell death. Pharmacol. Ther. 75:1997;153-177.
15. Sauer J.M., Waalkes M.P., Hooser S.B., Kuester R.K., McQueen C.A., Sipes I.G. Suppression of Kupffer cell function prevents cadmium induced hepatocellular necrosis in the male Sprague-Dawley rat. Toxicology. 121:1997;155-164.
16. Shiraishi N., Hochadel J.F., Coogan T.P., Koropatnick J., Waalkes M.P. Sensitivity to cadmium-induced genotoxicity in rat testicular cells is associated with minimal expression of the metallothionein gene. Toxicol. Appl. Pharmacol. 130:1995;229-236.
17. Siegers C.P., Schenke M., Younes M. Influence of cadmium chloride, mercuric chloride, and sodium vanadate on the glutathione-conjugating enzyme system in liver, kidney, and brain of mice. J. Toxicol. Environ. Health. 22:1987;141-148.
18. Son M.H., Kang K.W., Lee C.H., Kim S.G. Potentiation of cadmium-induced cytotoxicity by sulfur amino acid deprivation through activation of extracellular signal-regulated kinase1/2 (ERK1/2) in conjunction with p38 kinase or c-Jun N-terminal kinase (JNK): complete inhibition of the potentiated toxicity by U0126 an ERK1/2 and p38 kinase inhibitor. Biochem. Pharmacol. 62:2001;1379-1390.
19. Son M.H., Kang K.W., Lee C.H., Kim S.G. Potentiation of arsenic-induced cytotoxicity by sulfur amino acid deprivation through activation of ERK1/2, p38 kinase and JNK1: the distinct role of JNK1 in SAAD-potentiated mercury toxicity. Toxicol. Lett. 121:2001;45-55.
20. Staessen J., Amery A., Bernard A., Bruaux P., Buchet J.P., Claeys F., De Plaen P., Ducoffre G., Fagard R., Lauwerys R.R., et al. Effects of exposure to cadmium on calcium metabolism: a population study. Br. J. Ind. Med. 48:1991;710-714.
21. Yu B.P. Cellular defenses against damage from reactive oxygen species. Physiol. Rev. 74:1994;139-162.
22. White A.R., Bush A.I., Beyreuther K., Masters C.L., Cappai R. Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione. J. Neurochem. 72:1999;2092-2098.