Modulation of the stress response during apoptosis and necrosis induction in cadmium-treated U-937 human promonocytic cells

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1538, Issue 1, 2001, Pages 38-46

  Galán, Alba ^a   Troyano, Alfonso ^a   Vilaboa, Nuria E ^a   Fernández, Carlos ^a   De Blas, Elena ^a   Aller, Patricio ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Apoptosis; Cadmium; Necrosis; Stress response; U 937 promonocytic cell

Indexed keywords

ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; CADMIUM CHLORIDE; GLUTATHIONE; HEAT SHOCK FACTOR 1; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CADMIUM POISONING; CELL DEATH; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GLUTATHIONE METABOLISM; HEAT SHOCK; HEAT STRESS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN POLYMERIZATION;

ACETYLCYSTEINE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CADMIUM CHLORIDE; CHAPERONIN 60; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HEAT; HSP70 HEAT-SHOCK PROTEINS; HUMANS; METHIONINE SULFOXIMINE; MONOCYTES; NECROSIS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0035809068     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(00)00134-8     Document Type: Article

References (36)

1. The heat-shock proteins
2. Activation of human heat-shock genes is accompanied by oligomerization, modification and rapid translocation of heat-shock transcription factor HSF1
3. Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear translocation and can occur in the absence of stress
4. Multiple layers of regulation of human heat shock transcription factor 1
5. Possible involvement of poly (ADP-ribosyl) polymerase in triggering stress-induced apoptosis
6. Tobacco smoke induces apoptosis and necrosis in mammalian cells: Differential effects of HSP70
7. The shape of cell death
8. Apoptosis and necrosis: Intracellular ATP level as a determinant for cell death modes
9. Antioxidant-mediated inhibition of heat shock response leads to apoptosis
10. Butyrate induced apoptosis in lymphoid cells preceded by transient over-expression of HSP70 mRNA
11. Escaping cell death: Survival proteins in cancer
12. Overexpression of the heat shock protein 70 enhances the TCR/CD3- and Fas/Apo-1/CD95-mediated apoptotic cell death in Jurkat T cells
13. 2 in an oxidative stress-resistant cell line
14. cAMP increasing agents prevent the stimulation of heat-shock protein 70 (HSP70) gene expression by cadmium chloride in human myeloid cell lines
15. Uncoupling of apoptosis and Jun/AP-1 activity in human promonocytic cells treated with DNA-damaging and stress-inducing agents
16. Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells
17. The role of intracellular oxidation in death induction (apoptosis and necrosis) in human promonocytic cells treated with stress inducers (cadmium, heat, X-rays)
18. Establishment and characterization of a human histiocytic lymphoma cell line (U-937)
19. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
20. Heat-shock and cadmium chloride increase the vimentin mRNA and protein levels in U-937 human promonocytic cells
21. Glutathione depletion impairs transcriptional activation of heat shock genes in primary cultures of guinea pig gastric mucosal cells
22. Synthesis of hsp-70 is enhanced in glutathione-depleted Hep G2 cells
23. Induction of heat shock mRNA by cadmium is mediated by glutathione suppressive and non-suppressive triggers
24. Enhancement of expression of stress proteins by agents that lower the levels of glutathione in cells
25. 2 Role of thioredoxin
26. Multiple components of the HSP90 chaperone complex function in the regulation of heat shock factor 1 in vivo
27. Stressor-specific activation of heat-shock genes in H35 rat hepatoma cells
28. Vasopressin-induced heat-shock protein expression in renal tubular cells
29. Mitochondria and apoptosis
30. Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury
31. The Bcl-2 protein family
32. Cleavage of Bax enhances its cell death function
33. The Bcl-2 protein family
34. Redox regulation of caspase-3 (like) protease activity: Regulatory roles of thioredoxin and cytochrome c
35. A comparative study of apoptosis and necrosis in HepG2 cells: Oxidant-induced caspase inactivation leads to necrosis
36. Correlation between glutathione oxidation and trimerization of heat shock factor 1, an early step in stress induction of early Hsp response