Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1

Biochemical Journal

Volumn 373, Issue 2, 2003, Pages 583-591

  Phin, Sopheap ^a   Kupferwasser, Deborah ^a   Lam, Joseph ^a   Lee Fruman, Kay K ^a  

^a CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

Mammalian target of rapamycin (mTOR); p70 ribosomal S6 kinase 1 (S6K1); Phosphoinositide 3 kinase (PI3K); Phosphoinositide dependent protein kinase (PDK 1); Ribosomal S6 kinase 2 (S6K2)

Indexed keywords

AMINO ACIDS; CELLS; PROTEINS;

MUTATIONAL ANALYSIS;

ENZYMES;

AMINO ACID; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROLINE; PROTEIN KINASE; RAPAMYCIN; S6 KINASE; S6 KINASE 1; SERINE; THREONINE; UNCLASSIFIED DRUG; WORTMANNIN;

AMINO ACID SEQUENCE; ARTICLE; EMBRYO; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KIDNEY CELL; MUTAGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANTINEOPLASTIC AGENTS; CELLS, CULTURED; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHORYLATION; PRECIPITIN TESTS; PROLINE; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SERINE; SIGNAL TRANSDUCTION; SIROLIMUS; THREONINE; TRANSFECTION;

MAMMALIA;

EID: 0041845193     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021794     Document Type: Article

References (34)

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