Selenium causes growth inhibition and apoptosis in human brain tumor cell lines

Journal of Neuro-Oncology

Volumn 46, Issue 2, 2000, Pages 125-133

  Sundaram, Narayan ^a   Pahwa, Amit K ^a   Ard, March D ^a   Lin, Nan ^a   Perkins, Eddie ^a   Bowles Jr , Alfred P ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Fibroblasts; Human glioma cells; Mitochondria; MTT; Selenium; Ultrastructure

Indexed keywords

SELENIUM;

APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; BRAIN TUMOR; CELL GROWTH; GLIOMA CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; SKIN FIBROBLAST; TUMOR CELL CULTURE; TUMOR CELL LINE; ULTRASTRUCTURE;

APOPTOSIS; BRAIN NEOPLASMS; CELL DIVISION; CELLS, CULTURED; FIBROBLASTS; GROWTH INHIBITORS; HUMANS; MICROSCOPY, ELECTRON; MITOCHONDRIA; SELENIUM; SKIN;

EID: 0034118215     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006436326003     Document Type: Article

References (23)

1. Zhang ZH, Kimura M, Itokawa Y: Inhibitory effect of selenium and change of glutathione peroxidase activity on rat glioma. Biol Trac Elem Res 55: 31-38, 1996
2. Thompson KM, Haibach H, Evenson JK, Sunde RA: Liver selenium and testis phospholipid hydroperoxide glutathione peroxidase are associated with growth during selenium repletion of second-generation Se-deficient male rats. J Nutrition 128: 1289-1295, 1998
3. Esworthy RS, Swiderek KM, Ho YS, Chu FF: Selenium-dependent glutathione peroxidase-GI is a major glutathione peroxidase activity in the mucosal epithelium of rodent intestine. Biochim Biophys Acta 1381: 213-226, 1998
4. Sheehan TMT, Halls DJ: Measurement of selenium in clinical specimens. Ann Clin Biochem 36: 301-315, 1999
5. Sunde RA: Intracellular glutathione peroxidases: structure, regulation, and function. In: Selenium in Biology and Human Health. Burk RF (ed). Springer-Verlag, New York, pp 45-77
6. Philipov P, Tzatchev K: Selenium in serum of patients with cerebral and extracerebral tumors. Zentralbl Neurochir 49: 344-347, 1988
7. Haas HJ, Kopka ER, Sitzman FC: Selenium concentrations in the cerebrospinal fluid. Padiatr Padol 22: 115-121, 1987
8. El-Yazigi A, A-Saleh I, Al-Mefty O: Concentrations of Ag, Al, Au, Bi, Cd, Cu, Pb, Sb, and Se in cerebrospinal fluid of patients with cerebral neoplasms. Clinic Chem 30(8): 1358-1360, 1984.
9. Zhang Z, Kimura M, Itokawa Y: The decrement of carcinogenesis by dietary selenium and expression of placental form of glutathione-S-transferase in rat glioma. Biol Trac Elem Res 57: 147-155, 1997
10. Malvy DJ, Burtschy B, Arnaud J, Sommelet D, Leverger G, Dostalova L, Drucker J, Amedee-Manesme O: Serum beta-carotene and antioxidant micronutrients in children with cancer. The cancer in children and antioxidant micronutrients French study group. In J Epidemiol 22: 761-771, 1993
11. Knekt P, Aromaa A, Maatela J, Alfthan G, Aaran RK, Nikkari T, Hakama M, Hakulinen T, Teppo L: Serum micronutrients and risk of cancers of low incidence in Finland. Am J Epidemiol 134: 356-361, 1991
12. Harrison PR, Lanfear J, Wu L, Fleming J, McGarry L, Blower L: Chemopreventive and growth inhibitory effects of selenium. Biomed Environ Sci 10: 235-245, 1997
13. Zhu Z, Kimura M, Itokawa Y, Aoki T, Takahashi JA, Nakatsu S, Oda Y, Kikuchi H: Apoptosis induced by selenium in human glioma cells. Biol Trac Elem Res 54: 123-134, 1996
14. Mosmann, T: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63, 1983
15. Sternberg SS: Histology for Pathologists. Lippincott-Raven, Philadelphia, 1997, Chapter 1
16. Moses LE, Emerson JD, Hosseini H: Analyzing data from ordered categories. In: Medical Uses of Statistics. Bailar JC III, Mosteller F (eds). NEJM Books, Boston, 1992, pp 259-279
17. Zhu Z, Kimura M, Itokawa Y, Nakatsu S, Oda Y, Kikuchi H: Effect of selenium on malignant tumor cells of brain. Biol Trace Elem Res 49: 1-7, 1995
18. Van Vleet JF, Ferrans VJ, Ruth GR: Ultrastructural alterations in nutritional cardiomyopathy of selenium-vitamin E deficient swine. Lab Invest 37: 188-200, 1977
19. Hietaranta AJ, Nevalainen TJ, Aho HJ, Hamalainen OM, Suortamo SH: Pancreatic acinar cell necrosis with intact storage of digestive enzymes in selenomethionine treated rats. Virchows Arch B Cell Pathol Ind Mol Pathol 58: 397-403, 1990
20. Morrison DG, Pauly DF, Berdan RC, Dishart MK, Turner DS, Oborn CJ, Medina D: Mitochondrial inclusions and mitochondrial respiratory function in selenite-treated mammary epithelial cell lines. Anticancer Res 8: 65-72, 1988
21. Redman C, Scott JA, Baines AT, Basye JL, Clark LC, Calley C, Roe D, Payne CM, Nelson MA: Inhibitory effect of selenomethionine on the growth of three selected human tumor cell lines. Cancer Lett 125: 103-110, 1998
22. Wallach JB: Interpretation of Diagnostic Tests, Sixth Edition. Little, Brown, Boston, 1996, p 852
23. Philipov P, Tazatchev K: Selenium in the treatment of patients with brain gliomas. A pilot study. Zentralbl Neurochir. 51(3): 145-146,1990.