The In vitro inhibitory effect of flavonoid astilbin on 3-hydroxy-3-methylglutaryl coenzyme a reductase on vero cells

Chinese Medical Journal (Taipei)

Volumn 64, Issue 7, 2001, Pages 382-387

  Chen, T H ^a   Liu, J C ^a   Chang, J J ^a   Tsai, M F ^a   Hsieh, M H ^a   Chan, P ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Atherosclerosis; Chinese herbs; Hyperlipidemia

Indexed keywords

ACETIC ACID; ASTILBIN; DIMETHYL SULFOXIDE; FLAVONOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; MEVALONIC ACID; PRAVASTATIN;

ANIMAL CELL; ARTICLE; CELL GROWTH; CHINESE HERB; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; DRUG ISOLATION; ENZYME INHIBITION; GROWTH INHIBITION; IN VITRO STUDY; NONHUMAN; VERO CELL;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CELL DIVISION; CERCOPITHECUS AETHIOPS; FLAVONOIDS; FLAVONOLS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; VERO CELLS;

EID: 0034805005     PISSN: 05781337     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands
2. Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices
3. Flavonoids are scavengers of superoxide anions
4. Hydroxy radical scavenging activity of flavonoids
5. Inhibition of lipoxygenase-dependent lipid peroxidation by quercetin: Mechanism of antioxidative function
6. Protective effect of quercetin and rutin on photosensitized lysis of human erythrocytes in the presence of hematoporphyrin
7. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
8. Inhibition of mammalian 5-lipoxygenase and cyclooxygenase by flavonoids and phenolic dietary additives: Relationship to antioxidant activity and to iron ion-reducing ability
9. The flavonoids: A class of semi-essential food components: Their role in human nutrition
10. Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study
11. Flavonoid intake and long-term risk of coronary heart disease and cancer in the Seven Countries Study
12. Dietary flavonoids, antioxidant vitamins, and incidence of stroke
13. Effects of vitamin E and HMG-CoA reductase inhibition on cholesteryl ester transfer protein and lecithin-cholesterol acyltransferase in hypercholesterolemia
14. Ascorbic acid regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in guinea pig liver
15. Hypocholesterolemic effect of lycopene and beta-cartene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages
16. Semi-micro, dye-binding assay for rabbit interferon
17. Quercetin prevents the cytotoxicity of oxidized low-density lipoproteins by macrophages
18. Premature mortality from coronary heart disease: The Framingham Heart Study
19. Cholesterol and mortality: 30 years of follow-up from the Framingham Study
20. Serum total cholesterol and long-term coronary heart disease mortality in different cultures: Twenty-five year follow-up of the Seven Countries Study
21. An analysis of randomized trials evaluating the effect of cholesterol reduction on total mortality and coronary heart disease incidence
22. The value of lowering cholesterol after myocardial infarction
23. Cholesterol reduction in cardiovascular disease
24. Results of recent large cholesterol-lowering trials and their implications for clinical management
25. Biochemical, structural and functional properties of oxidized LDL
26. Alpha-tocopherol consumption during low-density-lipoprotein oxidation
27. Probucol inhibits oxidative modifications of LDL
28. Flavonoids inhibit the oxidative modification of LDL by macrophages
29. The Flavonoids
30. Chelating and free radical scavenging mechanism of inhibitory action of rutin and quercetin in lipid peroxidation