Aberrant methylation of the 5′ CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanINs

Cancer Biology and Therapy

Volumn 1, Issue 3, 2002, Pages 293-296

  Jansen, Marnix ^a,b   Fukushima, Noriyoshi ^a   Rosty, Christophe ^a   Walter, Kim ^a   Altink, Renee ^a,b   Van Heek, Tjarda ^a   Hruban, Ralph ^a   Offerhaus, Johan G ^b   Goggins, Michael ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

CpG island; Methylation; Pancreatic adenocarcinoma; PanIN; TSLC1

Indexed keywords

AZACITIDINE; BISULFITE; DNA; ENZYME INHIBITOR; IGSF4 PROTEIN, HUMAN; IMMUNOGLOBULIN; MEMBRANE PROTEIN; PRIMER DNA; PROTEIN; SULFITE; TUMOR SUPPRESSOR PROTEIN;

ADENOCARCINOMA; ARTICLE; CANCER STAGING; CASE CONTROL STUDY; CELL CULTURE; CHEMISTRY; COMPARATIVE STUDY; CPG ISLAND; DNA METHYLATION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; AZACITIDINE; CARCINOMA, PANCREATIC DUCTAL; CASE-CONTROL STUDIES; CPG ISLANDS; DNA METHYLATION; DNA PRIMERS; DNA, NEOPLASM; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOGLOBULINS; MEMBRANE PROTEINS; NEOPLASM STAGING; PANCREATIC NEOPLASMS; PROMOTER REGIONS (GENETICS); PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SULFITES; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0041559969     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.84     Document Type: Article

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