SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells

Cytokine

Volumn 20, Issue 4, 2002, Pages 141-147

  Brockdorff, Johannes Lundin ^a   Woetmann, Anders ^a   Mustelin, Tomas ^b   Kaltoft, Keld ^c   Zhang, Qian ^d   Wasik, Mariusz A ^d   Röpke, Carsten ^a   Ødum, Niels ^a,e  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b BURNHAM INSTITUTE   (United States)

^c AARHUS UNIVERSITY   (Denmark)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

CTCL; IL 2; MAPK; SHP2; Stat

Indexed keywords

INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE; STAT3 PROTEIN; STAT5 PROTEIN; DNA; DNA BINDING PROTEIN; HYBRID PROTEIN; MAP3K1 PROTEIN, HUMAN; MILK PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; SRC HOMOLOGY 2 (SH2) DOMAIN CONTAINING PHOSPHATASES; SRC HOMOLOGY-2 (SH2) DOMAIN-CONTAINING PHOSPHATASES; STAT3 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TUMOR PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LYMPHOMA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; T CELL LYMPHOMA; UPREGULATION; WILD TYPE; AMINO ACID SUBSTITUTION; CELL CULTURE; CHEMISTRY; DRUG EFFECT; GENETICS; METABOLISM; MISSENSE MUTATION; MYCOSIS FUNGOIDES; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

AMINO ACID SUBSTITUTION; DNA, NEOPLASM; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-2; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MILK PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION, MISSENSE; MYCOSIS FUNGOIDES; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RECOMBINANT FUSION PROTEINS; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0041520659     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2002.1986     Document Type: Article

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