Spread and survival of promiscuous IncP-1 plasmids

Acta Biochimica Polonica

Volumn 50, Issue 2, 2003, Pages 425-453

  Adamczyk, Małgorzata ^a   Jagura Burdzy, Grazyna ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

Central control region; Global regulation; IncP 1 plasmids; Stable maintenance

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTIBIOTIC AGENT; KANAMYCIN; PENICILLIN G; POLYMER; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; DIMERIZATION; DNA SEQUENCE; DNA TRANSFER; ENZYME ACTIVITY; ESCHERICHIA COLI; EUKARYOTE; GENE; GENE EXPRESSION REGULATION; GENE REPLICATION; GENE SEQUENCE; GENOMICS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IMMUNOFLUORESCENCE; KLEBSIELLA AEROGENES; KORA GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERATOR GENE; OPERON; PARA GENE; PARB GENE; PARC GENE; PLASMID; PSEUDOMONAS AERUGINOSA; REVIEW; TRANSPOSON; YEAST;

BACTERIA (MICROORGANISMS); BETAPROTEOBACTERIA; ESCHERICHIA COLI; EUKARYOTA; KLEBSIELLA; KLEBSIELLA AEROGENES; NEGIBACTERIA; POSIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; TRANSPOSONS;

EID: 0041379642     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.2003_3696     Document Type: Review

References (138)

1. Austin S, Ziese M, Sternberg N. (1981) A novel role for site-specific recombination in maintenance of bacterial replicons. Cell.; 25: 729-36.
2. Balzer D, Ziegelin G, Pansegrau W, Kruft V, Lanka E. (1992) KorB protein of promiscuous plasmid RP4 recognizes inverted sequence repetitions in regions essential for conjugative plasmid transfer. Nucleic Acids Res.; 20: 1851-8.
3. Beil S, Timmis KN, Pieper DH. (1999) Genetic and biochemical analyses of the tec operon suggest a route for evolution of chlorobenzene degradation genes. J Bacteriol.; 181: 341-6.
4. Bhattacharayya A, Figurski DH. (2001) A small protein-protein interaction domain common to KlcB and global regulators of KorA and TrbA of promiscuous IncP plasmids. J Mol Biol.; 310: 51-61.
5. Bignell CR, Haines AS, Khare D, Thomas CM. (1999) Effect of growth rate and incC mutation on symmetric plasmid distribution by the IncP-1 partitioning apparatus. Mol Microbiol.; 34: 205-16.
6. Bignell CR, Thomas CM. (2001) The bacterial ParA-ParB partitioning proteins. J Biotechnol.; 91: 1-34.
7. Bouet J-Y, Funnell BE. (1999) P1 ParA interacts with the P1 partition complex at parS and ATP-ADP-switch controls ParA activities. EMBO J.; 18: 1415-24.
8. Burlage RS, Bemis LA, Layton AC, Sayler GS, Larimer F. (1990) Comparative genetic organization of incompatibility group P degradative plasmids. J Bacteriol.; 172: 6818-25.
9. Burland V, Shao Y, Perna NT, Plunkett G, Sofia HJ, Blattner FR. (1998) The complete DNA sequence and analysis of the large virulence plasmid of Escherichia coli O157:H7. Nucleic Acids Res.; 26: 4196-204.
10. Cabezon E, Lanka E, de la Cruz CF. (1994) Requirements for mobilization of plasmids RSF1010 and ColE1 by the IncW plasmid R388: trwB and RP4 traG are interchangeable. J Bacteriol.; 176: 4455-8.
11. Caspi R, Pacek M, Consiglieri G, Helinski DR, Toukdarian A, Konieczny I. (2001) A broad host range replicon with different requirements for replication initiation in three bacterial species. EMBO J.; 20: 3262-71.
12. Cerin H, Hackett J. (1989) Molecular cloning and analysis of the incompatibility and partition functions of the virulence plasmid of Salmonella typhimurium. Microb Pathog.; 7: 85-99.
13. Cerin H, Hackett J. (1993) The parVP region of the Salmonella typhimurium virulence plasmid pSLT contains four loci required for incompatibility and partition. Plasmid.; 30: 30-8.
14. Close SM, Kado CI. (1992) A gene near the plasmid pSa origin of replication encodes a nuclease. Mol Microbiol.; 6: 521-7.
15. Dam M, Gerdes K. (1994) Partitioning of plasmid R1. Ten direct repeats flanking the parA promoter constitute a centromere-like partition site parC that expresses incompatibility. J Mol Biol.; 236: 1289-98.
16. Daugelavicius R, Bamford JK, Grahn AM, Lanka E, Bamford DH. (1997) The IncP plasmid-encoded cell envelope-associated DNA transfer complex increases cell permeability. J Bacteriol.; 179: 5195-202.
17. Davey MJ, Funnell BE. (1997) Modulation of the P1 plasmid partition protein ParA by ATP, ADP, and P1 ParB. J Biol Chem.; 272: 15286-92.
18. Delbruck H, Ziegelin G, Lanka E, Heinemann U. (2002) An Src homology 3-like domain is responsible for dimerization of the repressor protein KorB encoded by the promiscuous IncP plasmid RP4. J Biol Chem.; 277: 4191-8.
19. Doran KS, Helinski DR, Konieczny I. (1999) Host-dependent requirement for specific DnaA boxes for plasmid RK2 replication. Mol Microbiol.; 33: 490-8.
20. Droge M, Puhler A, Selbitschka W. (2000) Phenotypic and molecular characterization of conjugative antibiotic resistance plasmids isolated from bacterial communities of activated sludge. Mol Gen Genet.; 263: 471-82.
21. Easter CL, Schwab H, Helinski DR. (1998) Role of the parCBA operon of the broad-host-range plasmid RK2 in stable plasmid maintenance. J Bacteriol.; 180: 6023-30.
22. Eisenbrandt R, Kalkum M, Lai EM, Lurz R, Kado CI, Lanka E. (1999) Conjugative pili of IncP plasmids, and the Ti plasmid T pilus are composed of cyclic subunits J. Biol Chem.; 274: 22548-55.
23. Eisenbrandt R, Kalkum M, Lurz R, Lanka E. (2000) Maturation of IncP pilin precursors resembles the catalytic dyad-like mechanism of leader peptidases. J Bacteriol.; 182: 6751-61.
24. Engelberg-Kulka H, Glaser G. (1999) Addiction modules and programmed cell death and antideath in bacterial cultures. Annu Rev Microbiol.; 53: 43-70.
25. Erdmann N, Petroff T, Funnell BE. (1999) Intracellular localization of P1 ParB protein depends on ParA and parS. Proc Natl Acad Sci USA.; 96: 14905-10.
26. Frohme M, Camargo AA, Heber S, Czink C, Simpson AJ, Hoheisel JD, de Souza AP. (2000) Mapping analysis of the Xylella fastidiosa genome. Nucleic Acids Res.; 28: 3100-4.
27. Gerdes K, Moller-Jensen J, Bugge JR. (2000) Plasmid and chromosome partitioning: surprises from phylogeny. Mol Microbiol.; 37: 455-66.
28. Gerlitz M, Hrabak O, Schwab H. (1990) Partitioning of broad-host-range plasmid RP4 is a complex system involving site-specific recombination. J Bacteriol.; 172: 6194-203.
29. Giebelhaus LA, Frost L, Lanka E, Gormley EP, Davies JE, Leskiw B. (1996) The Tra2 core of the IncP(alpha) plasmid RP4 is required for intergeneric mating between Escherichia coli and Streptomyces lividans. J Bacteriol.; 178: 6378-81.
30. Godfrin-Estevenon A-M, Pasta F, Lane D. (2002) The parAB gene products of Pseudomonas putida exhibit partition activity in both P. putida and Escherichia coli. Mol Microbiol.; 43: 39-49.
31. Gotz A, Pukall R, Smit E, Tietze E, Prager R, Tschape H, van Elsas JD, Smalla K. (1996) Detection and characterization of broad-host-range plasmids in environmental bacteria by PCR. Appl Environ Microbiol.; 62: 2621-8.
32. Grahn AM, Haase J, Bamford DH, Lanka E. (2000) Components of the RP4 conjugative transfer apparatus form an envelope structure bridging inner and outer membranes of donor cells: implications for related macromolecule transport systems. J Bacteriol.; 182: 1564-74.
33. Greated A, Titok M, Krasowiak R, Fairclough RJ, Thomas CM. (2000) The replication and stable-inheritance functions of IncP-9 plasmid pM3. Microbiology.; 146: 2249-58.
34. Grigoriev PS, Lobocka MB. (2001) Determinants of segregational stability of the linear plasmid-prophage N15 of Escherichia coli. Mol Microbiol.; 42: 355-68.
35. Haase J, Lurz R, Grahn AM, Bamford DH, Lanka E. (1995) Bacterial conjugation mediated by plasmid RP4: RSF1010 mobilization, donor-specific phage propagation, and pilus production require the same Tra2 core components of a proposed DNA transport complex. J Bacteriol.; 177: 4779-91.
36. Haase J, Kalkum M, Lanka E. (1996) TrbK, a small cytoplasmic membrane lipoprotein, functions in entry exclusion of the IncP alpha plasmid RP4. J Bacteriol.; 178: 6720-9.
37. Haneda T, Okada N, Nakazawa N, Kawakami T, Danbara H. (2001) Complete DNA sequence and comparative analysis of the 50-kilobase virulence plasmid of Salmonella enterica serovar Choleraesuis. Infect Immun.; 69: 2612-20.
38. Hayakawa Y, Murotsu T, Matsubara K. (1985) Mini-F protein that binds to a unique region for partition of mini-F plasmid DNA. J Bacteriol.; 163: 349-54.
39. Hayes F. (2000) The partition system of multidrug resistance plasmid TP228 includes a novel protein that epitomizes an evolutionarily distinct subgroup of the ParA superfamily. Mol Microbiol.; 37: 528-41.
40. Heidelberg JF, Eisen J A, Nelson WC, Clayton RA, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Umayam L, Gill SR, Nelson KE, Read TD, Tettelin H, Richardson D, Ermolaeva MD, Vamathevan J, Bass S, Qin H, Dragoi I, Sellers P, McDonald L, Utterback T, Fleishmann RD, Nierman WC, White O. (2000) DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature.; 406: 477-83.
41. Heinemann JA, Sprague GF Jr. (1989) Bacterial conjugative plasmids mobilize DNA transfer between bacteria and yeast. Nature.; 340: 205-9.
42. Helsberg M, Eichenlaub R. (1986) Twelve 43-base-pair repeats map in a cis-acting region essential for partition of plasmid mini-F. J Bacteriol.; 165: 1043-5.
43. Ho TQ, Zhong Z, Aung S, Pogliano J. (2002) Compatible bacterial plasmids are targeted to independent cellular locations in Escherichia coli. EMBO J.; 21: 1864-72.
44. Hooper SW, Dockendorff TC, Sayler GS. (1989) Characteristics and restriction analysis of the 4-chlorobiphenyl catabolic plasmid, pSS50. Appl Environ Microbiol.; 55: 1286-8.
45. Ireton K, Gunther NW, Grossman AD. (1994) Spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis. J Bacteriol.; 176: 5320-9.
46. Jagura-Burdzy G, Ibbotson JP, Thomas CM. (1991) The korF region of broad-host-range plasmid RK2 encodes two polypeptides with transcriptional repressor activity. J Bacteriol.; 173: 826-33.
47. Jagura-Burdzy G, Thomas CM. (1992) kfrA gene of broad host range plasmid RK2 encodes a novel DNA-binding protein. J Mol Biol.; 225: 651-60.
48. Jagura-Burdzy G, Thomas CM. (1994) KorA protein of promiscuous plasmid RK2 controls a transcriptional switch between divergent operons for plasmid replication and conjugative transfer. Proc Natl Acad Sci U S A.; 91: 10571-5.
49. Jagura-Burdzy G, Thomas CM. (1995) Purification of KorA protein from broad host range plasmid RK2: definition of a hierarchy of KorA operators. J Mol Biol.; 253: 39-50.
50. Jagura-Burdzy G, Macartney DP, Zatyka M, Cunliffe L, Cooke D, Huggins C, Westblade L, Khanim F, Thomas CM. (1999a) Repression at a distance by the global regulator KorB of promiscuous IncP plasmids. Mol Microbiol.; 32: 519-32.
51. Jagura-Burdzy G, Kostelidou K, Pole J, Khare D, Jones A, Williams DR Thomas CM. (1999b) IncC of broad-host-range plasmid RK2 modulates KorB transcriptional repressor activity in vivo and operator binding in vitro. J Bacteriol.; 181: 2807-15.
52. Jensen RB, Gerdes K. (1999) Mechanism of DNA segregation in prokaryotes: ParM partitioning protein of plasmid R1 co-localizes with its replicon during the cell cycle. EMBO J.; 18: 4076-84.
53. Jiang Y, Pogliano J, Helinski DR, Konieczny I. (2002) ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase. Mol Microbiol.; 44: 971-9.
54. Johnson EP, Strom AR, Helinski DR. (1996) Plasmid RK2 toxin protein ParE: purification and interaction with the ParD antitoxin protein. J Bacteriol.; 178: 1420-9.
55. Johnson EP, Mincer T, Schwab H, Burgin AB, Helinski DR. (1999) Plasmid RK2 ParB protein: purification and nuclease properties. J Bacteriol.; 181: 6010-8.
56. Jovanovic OS, Figurski DH. (1997) A potential new gene (tccA) on IncP plasmid RK2 and transposon Tn1721: relationship of its product to the TrwC relaxase/helicase of IncW plasmid R388. Plasmid.; 38: 220-3.
57. Kim SK, Shim J. (1999) Interaction between F plasmid partition proteins SopA and SopB. Biochem Biophys Res Commun.; 263: 113-7.
58. Konieczny I, Helsinki, DR. (1997a) Helicase delivery and activation by DnaA and TrfA proteins during the initiation of replication of the broad host range plasmid RK2. J Biol Chem.; 272: 33312-8.
59. Konieczny I, Helsinki DR. (1997b) The replication initiation protein of the broad-host-range plasmid RK2 is activated by the ClpX chaperone. Proc Natl Acad Sci U S A.; 94: 14378-82.
60. Konieczny I, Doran KS, Helinski DR, Blasina A. (1997) Role of TrfA and DnaA proteins in origin opening during initiation of DNA replication of the broad host range plasmid RK2. J Biol Chem.; 272: 20173-8.
61. Konieczny I, Liberek K. (2002) Cooperative action of Escherichia coli ClpB protein and DnaK chaperone in the activation of a replication initiation protein. J Biol Chem.; 277: 18483-8.
62. Koonin EV. (1993) A superfamily of ATPases with diverse functions containing either classical or deviant ATP-binding motif. J Mol Biol.; 229: 1165-74.
63. Kornacki JA, Burlage RS, Figurski DH. (1990) The kil-kor regulon of broad-host range plasmid RK2: nucleotide sequence, polypeptide product, and expression of regulatory gene korC. J Bacteriol.; 172: 3040-50
64. Kostelidou K, Jagura-Burdzy G, Thomas CM. (1998) Mutational analysis of the global regulator KorA of broad-host-range plasmid RK2. J Mol Biol.; 281: 453-63.
65. Kostelidou K, Jones AC, Thomas CM. (1999) Conserved C-terminal region of global repressor KorA of broad-host-range plasmid RK2 is required for co-operativity between KorA and a second RK2 global regulator, KorB. J Mol Biol.; 289: 211-21.
66. Kostelidou K, Thomas CM. (2000) The hierarchy of KorB binding at its 12 binding sites on the broad-host-range plasmid RK2 and modulation of this binding by IncC1 protein. J Mol Biol.; 295: 411-22.
67. Kostelidou K, Thomas CM. (2002) DNA recognition by the KorA proteins of IncP-1 plasmids RK2 and R751. Biochim Biophys Acta.; 1576: 110-8.
68. Krause S, Barcena M, Pansegrau W, Lurz R, Carazo JM, Lanka E. (2000a) Sequence-related protein export NTPases encoded by the conjugative transfer region of RP4 and by the cag pathogenicity island of Helicobacter pylori share similar hexameric ring structures. Proc Natl Acad Sci U S A.; 97: 3067-72.
69. Krause S, Pansegrau W, Lurz R, de la Cruz CF, Lanka E. (2000b) Enzymology of type IV macromolecule secretion systems: the conjugative transfer regions of plasmids RP4 and R388 and the cag pathogenicity island of Helicobacter pylori encode structurally and functionally related nucleoside triphosphate hydrolases. J Bacteriol.; 182: 2761-70.
70. Kwong SM, Yeo CC, Chuah D, Poh CL. (1998) Sequence analysis of plasmid pRA2 from Pseudomonas alcaligenes NCIB 9867 (P25X) reveals a novel replication region. FEMS Microbiol Lett.; 158: 159-65.
71. Kwong SM, Yeo CC, Suwanto A, Poh CL. (2000) Characterization of the endogenous plasmid from Pseudomonas alcaligenes NCIB 9867: DNA sequence and mechanism of transfer. J Bacteriol.; 182: 81-90.
72. Lane D, Rothenbuehler R, Merrillat AM, Aiken C. (1987) Analysis of the F plasmid centromere. Mol Gen Genet.; 207: 406-12.
73. Larsen MH, Figurski DH. (1994) Structure, expression, and regulation of the kilC operon of promiscuous IncP alpha plasmids. J Bacteriol.; 176: 5022-32.
74. Lawley TD, Gordons GS, Wright A, Taylor DE. (2002) Bacterial conjugative transfer: visualization of successful mating pairs and plasmid establishment in live Escherichia coli. Mol Microbiol.; 44: 947-56.
75. Leveau JH, van der Meer JR. (1997) Genetic characterization of insertion sequence ISJP4 on plasmid pJP4 from Ralstonia eutropha JMP134. Gene.; 202: 103-14.
76. Lewis PJ, Errington J. (1997) Direct evidence for active segregation of oriC regions of the Bacillus subtilis chromosome and co-localization with the Spo0J partitioning protein. Mol Microbiol.; 2: 945-54.
77. Lewis RA, Bignell CR, Zeng W, Jones AC, Thomas CM. (2002) Chromosome loss from par mutants of Pseudomonas putida depends on growth medium and phase of growth. Microbiology.; 148: 537-48.
78. Li Y, Austin S. (2002) The P1 plasmid in action: time-lapse photomicroscopy reveals some unexpected aspects of plasmid partition. Plasmid.; 48: 174-8.
79. Lin Z, Mallavia LP. (1994) Identification of a partition region carried by the plasmid QpH1 of Coxiella burnetii. Mol Microbiol.; 13: 513-23.
80. Lin Z, Mallavia LP. (1998) Membrane association of active plasmid partitioning protein A in Escherichia coli. J Biol Chem.; 273: 11302-12.
81. Lin Z, Hiasa H, Kumar U, DiGate RJ. (1997) The traE gene of plasmid RP4 encodes a homologue of Escherichia coli DNA topoisomerase III. J Biol Chem.; 272: 19582-7.
82. Lobocka M, Yarmolinsky M. (1996) P1 plasmid partition: a mutational analysis of ParB. J Mol Biol.; 259: 366-82.
83. Lukaszewicz M, Kostelidou K, Bartosik A, Cooke GD, Thomas CM, Jagura-Burdzy G. (2002) Functional dissection of the ParB homologue (KorB) from IncP-1 plasmid RK2. Nucleic Acids Res.; 30: 1046-55.
84. Macartney DP, Williams DR, Stafford T, Thomas CM. (1997) Divergence and conservation of the partitioning and global regulation functions in the central control region of the IncP plasmids RK2 and R751. Microbiology.; 143: 2167-77.
85. Martinez B, Tomkins J, Wackett LP, Wing R, Sadowsky MJ. (2001) Complete nucleotide sequence and organization of the atrazine catabolic plasmid pADP-1 from Pseudomonas sp. strain ADP. J Bacteriol.; 183: 5684-97.
86. Masuda Y, Miyakawa K, Nishimura Y, Ohtsubo E. (1993) chpA and chpB, Escherichia coli chromosomal homologues of the peru locus responsible for stable maintenance of plasmid R100. J Bacteriol.; 175: 6850-6.
87. Mohl DA, Gober JW. (1997) Cell cycle-dependent polar localization of chromosome partitioning proteins in Caulobacter crescentus. Cell.; 88: 675-84.
88. Mohl DA, Easter J, Gober JW. (2001) The chromosome partitioning protein, ParB, is required for cytokinesis in Caulobacter crescentus. Mol Microbiol.; 42: 741-55.
89. Moller-Jensen J, Jensen RB, Lowe J, Gerdes K. (2002) Prokaryotic DNA segregation by an actin-like filament. EMBO J.; 21: 3119-27.
90. Motallebi-Veshareh M, Rouch DA, Thomas CM. (1990) A family of ATPases involved in active partitioning of diverse bacterial plasmids. Mol Microbiol.; 4: 1455-63.
91. Motallebi-Veshareh M, Balzer D, Lanka E, Jagura-Burdzy G, Thomas CM. (1992) Conjugative transfer functions of broad-host-range plasmid RK2 are coregulated with vegetative replication. Mol Microbiol.; 6: 907-20.
92. Mysliwiec TH, Errington J, Vaidya AB, Bramucci MG. (1991) The Bacillus subtilis spo0J gene: evidence for involvement in catabolite repression of sporulation. J Bacteriol.; 173: 1911-9.
93. Oberer M, Zangger K, Prytulla S, Keller W. (2002) The anti-toxin ParD of plasmid RK2 consists of two structurally distinct moieties and belongs to the ribbon-helix-helix family of DNA-binding proteins. Biochem J.; 361: 41-7.
94. Ogasawara N, Yoshikawa H. (1992) Genes and their organization in the replication origin region of the bacterial chromosome. Mol Microbiol.; 6: 629-34.
95. Pansegrau W, Lanka E. (1996) Mechanisms of initiation and termination reactions in conjugative DNA processing. Independence of tight substrate binding and catalytic activity of relaxase (TraI) of IncPα plasmid RP4. J Biol Chem.; 271: 13068-76.
96. Pansegrau W, Lanka E, Barth PT, Figurski DH, Guiney DG, Haas D, Helinski DR, Schwab H, Stanisich VA, Thomas CM. (1994) Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis. J Mol Biol.; 239: 623-63.
97. Pettigrew CA, Breen A, Corcoran C, Sayler GS. (1990) Chlorinated biphenyl mineralization by individual populations and consortia of freshwater bacteria. Appl Environ Microbiol.; 56: 2036-45.
98. Pinkney M, Ramon D, Lanka E, Thomas MC. (1988) Replication of mini RK2 plasmid in extracts of Escherichia coli requires plasmid-encoded protein TrfA and host-encoded proteins DnaA, B, G DNA gyrase and DNA polymerase III. J Mol Biol.; 203: 927-38.
99. Pogliano J, Ho TQ Zhong Z, Helinski DR. (2001) Multicopy plasmids are clustered and localized in Escherichia coli. Proc Natl Acad Sci U S A.; 98: 4486-91.
100. Pogliano J. (2002) Dynamic cellular location of bacterial plasmids. Curr Opin Microbiol.; 5: 586-90.
101. Quisel JD, Grossman AD. (2000) Control of sporulation gene expression in Bacillus subtilis by the chromosome partitioning proteins Soj (ParA) and Spo0J (ParB). J Bacteriol.; 182: 3446-51.
102. Ravin N, Lane D. (1999) Partition of the linear plasmid N15: interactions of N15 partition functions with the sop locus of the F plasmid. J Bacteriol.; 181: 6898-906.
103. Roberts RC, Helinski DR. (1992) Definition of a minimal plasmid stabilization system from the broad-host-range plasmid RK2. J Bacteriol.; 174: 8119-32.
104. Roberts RC, Spangler C, Helinski DR. (1993) Characteristics and significance of DNA binding activity of plasmid stabilization protein ParD from the broad host-range plasmid RK2. J Biol Chem.; 268: 27109-17.
105. Santini JM, Stanisich VA. (1998) Both the fipA gene of pKM101 and the pifC gene of F inhibit conjugal transfer of RP1 by an effect on traG. J Bacteriol.; 180: 4093-101.
106. Schneiker S, Keller M, Droge M, Lanka E, Puhler A, Selbitschka W. (2001) The genetic organization and evolution of the broad host range mercury resistance plasmid pSB102 isolated from a microbial population residing in the rhizosphere of alfalfa. Nucleic Acids Res.; 29: 5169-81.
107. Sharpe ME, Hauser PM, Sharpe RG, Errington J. (1998) Bacillus subtilis cell cycle as studied by fluorescence microscopy: constancy of cell length at initiation of DNA replication and evidence for active nucleoid partitioning. J Bacteriol.; 180: 547-55.
108. Sia EA, Roberts RC, Easter C, Helinski DR, Figurski DH. (1995) Different relative importance of the par operons and the effect of conjugal transfer on the maintenance of intact promiscuous plasmid RK2. J Bacteriol.; 177: 2789-97.
109. Siddique A, Figurski DH. (2002) The active partition gene incC of IncP plasmids is required for stable maintenance in a broad range of hosts. J Bacteriol.; 184: 1788-93.
110. Smith CA, Shingler V, Thomas CM. (1984) The trfA and trfB promoter regions of broad host range plasmid RK2 share common potential regulatory sequences. Nucleic Acids Res.; 12: 3619-30.
111. Smith CA, Thomas CM. (1985) Comparison of the nucleotide sequence of the vegetative replication origins of broad host range plasmids R751 and RK2 reveals conserved features of probable functional importance. Nucleic Acids Res.; 13: 557-72.
112. Smith CA, Thomas CM. (1987) Comparison of the organisation of the genomes of phenotypically diverse plasmids of incompatibility group P: members of the IncP beta sub-group are closely related. Mol Gen Genet.; 206: 419-27.
113. Smith CA, Thomas CM. (1989) Relationships and evolution of IncP plasmids. In Promiscuous plasmids of gram-negative bacteria. Thomas CM, ed. Academic Press, London.
114. Summers DK, Beton CW, Withers HL. (1993) Multicopy plasmid instability: the dimer catastrophe hypothesis. Mol Microbiol.; 8: 1031-8.
115. Surtees JA, Funnell BE. (1999) P1 ParB domain structure includes two independent multimerization domains. J Bacteriol.; 181: 5898-908.
116. Szpirer CY, Faelen M, Couturier M. (2000) Interaction between the RP4 coupling protein TraG and the pBHR1 mobilization protein Mob. Mol Microbiol.; 37: 1283-92.
117. Tauch A, Schneiker S, Selbitschka W, Puhler A, van Overbeek L S, Smalla K, Thomas CM, Bailey MJ, Forney LJ, Weightman A, Ceglowski P, Pembroke T, Tietze E, Schroder G, Lanka E, van Elsas JD. (2002) The complete nucleotide sequence and environmental distribution of the cryptic, conjugative, broad-host-range plasmid pIPO2 isolated from bacteria of the wheat rhizosphere. Microbiology.; 148: 1637-53.
118. Thomas CM, Cross MA, Hussain AA, Smith CA. (1984) Analysis of copy number control elements in the region of the vegetative replication origin of broad host range plasmid RK2. EMBO J.; 3: 57-63.
119. Thomas CM, Ibbotson JP, Wang NY, Smith CA, Tipping R, Loader NM. (1988) Gene regulation on broad host range plasmid RK2: identification of three novel operons whose transcription is repressed by both KorA and KorC. Nucleic Acids Res.; 16: 5345-59.
120. Thomas CM, Smith CA. (1987) Incompatibility group P plasmids: genetics, evolution, and use in genetic manipulation. Annu Rev Microbiol.; 41: 77-101.
121. Thomas CM, Theophilus BD, Johnston L, Jagura-Burdzy G, Schilf W, Lurz R, Lanka E. (1990) Identification of a seventh operon on plasmid RK2 regulated by the korA gene product. Gene.; 89: 29-35.
122. Thorsted PB, Shah DS, Macartney D, Kostelidou K, Thomas CM. (1996) Conservation of the genetic switch between replication and transfer genes of IncP plasmids but divergence of the replication functions which are major host-range determinants. Plasmid.; 36: 95-111.
123. Thorsted PB, Macartney DP, Akhtar P, Haines AS, Ali N, Davidson P, Stafford T, Pocklington MJ, Pansegrau W, Wilkins BM, Lanka E, Thomas CM. (1998) Complete sequence of the IncPbeta plasmid R751: implications for evolution and organisation of the IncP backbone. J Mol Biol.; 282: 969-90.
124. Toukdarian AE, Helinski DR. (1998) TrfA dimers play a role in copy-number control of RK2 replication. Gene.; 223: 205-11.
125. Top E, De Smet I, Verstraete W, Dijkmans R, Mergeay M. (1994) Exogenous isolation of mobilizing plasmids from polluted soils and sludges. Appl Environ Microbial.; 60: 831-9.
126. Tralau T, Cook AM, Ruff J. (2001) Map of the IncP1beta plasmid pTSA encoding the wide-spread genes (tsa) for p-toluenesulfonate degradation in Comamonas testosteroni T-2. Appl Environ Microbiol.; 67: 1508-16.
127. Van den Ent F, Moller-Jensen J, Amos LA, Gerdes K, Lowe J. (2002) F-actin-like filaments formed by plasmid segregation protein ParM. EMBO J.; 21: 6935-43.
128. Vogel JP, Andrews HL, Wang SK, Isberg RR. (1998) Conjugative transfer by the virulence system of Legionella pneumophila. Science.; 279: 873-6.
129. Watanabe E, Wachi M, Yamasaki M, Nagai K. (1992) ATPase activity of SopA, a protein essential for active partitioning of F plasmid. Mol Gen Genet.; 234: 249-352.
130. Waters VL. (2001) Conjugation between bacterial and mammalian cells. Nat Genet.; 29: 375-6.
131. Williams DR, Motallebi-Veshareh M, Thomas CM. (1993) Multifunctional repressor KorB can block transcription by preventing isomerization of RNA polymerase-promoter complexes. Nucleic Acids Res.; 21: 1141-8.
132. Williams DR, Macartney DP, Thomas CM. (1998) The partitioning activity of the RK2 central control region requires only incC, korB and KorB-binding site O(B)3 but other KorB-binding sites form destabilizing complexes in the absence of O(B)3. Microbiology.; 144: 3369-78.
133. Williams DR, Thomas CM. (1992) Active partitioning of bacterial plasmids. J Gen Microbiol.; 138: 1-16.
134. Wilson JW, Sia EA, Figurski DH. (1997) The kilE locus of promiscuous IncP alpha plasmid RK2 is required for stable maintenance in Pseudomonas aeruginosa. J Bacteriol.; 179: 2339-47.
135. Wilson JW, Figurski DH. (2002) Host-specific incompatibility by 9-bp direct repeats indicates a role in the maintenance of broad-host-range plasmid RK2. Plasmid.; 47: 216-23.
136. Yakobson E, Guiney DG. (1983) Homology in the transfer origins of broad host range IncP plasmids. Definition of two subgroups of P plasmids. Mol Gen Genet.; 192: 436-8.
137. Zatyka M, Jagura-Burdzy G, Thomas CM. (1994) Regulation of transfer genes of promiscuous IncP alpha plasmid RK2: repression of Tra1 region transcription both by relaxosome proteins and by the Tra2 regulator TrbA. Microbiology.; 140: 2981-90.
138. Zatyka M, Bingle L, Jones AC, Thomas CM. (2001) Cooperativity between KorB and TrbA repressors of broad-host-range plasmid RK2. J. Bacteriol.; 183: 1022-31.