메뉴 건너뛰기




Volumn 13, Issue 3, 2003, Pages 169-179

Acrylonitrile-induced neurotoxicity in normal human astrocytes: Oxidative stress and 8-hydroxy-2′-deoxyguanosine formation

Author keywords

8 Hydroxy 2 deoxyguanosine; Acrylonitrile; Astrocytes; Catalase; Glutathione; Oxidative Stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACRYLONITRILE; ANTIOXIDANT; CATALASE; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0041358778     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510309836     Document Type: Article
Times cited : (19)

References (71)
  • 1
    • 47049114626 scopus 로고
    • Immunoenzymatic assay of mouse and human cytokines using NIP-labeled anticytokine antibodies
    • ed. J. Coligan, A. Kruisbeck, D. Marulies, E. Shevach, and W. Strober. New York: John Wiley
    • Abrams, J. S. 1995. Immunoenzymatic assay of mouse and human cytokines using NIP-labeled anticytokine antibodies. In Current Protocols in Immunology, ed. J. Coligan, A. Kruisbeck, D. Marulies, E. Shevach, and W. Strober, 6-20. New York: John Wiley.
    • (1995) Current Protocols in Immunology , pp. 6-20
    • Abrams, J.S.1
  • 2
    • 0019199109 scopus 로고
    • Metabolism of acrylonitrile to cyanide
    • Abreu, M. E., and Ahmed, A. E. 1980. Metabolism of acrylonitrile to cyanide. Drug Metab. Dispos. 8:376-379.
    • (1980) Drug Metab. Dispos. , vol.8 , pp. 376-379
    • Abreu, M.E.1    Ahmed, A.E.2
  • 4
    • 0021318441 scopus 로고
    • Catalase in vitro
    • ed. P. Sidney, K. Colomic, and O. Nathan. New York: Academic Press
    • Aebi, H. 1984. Catalase in vitro. In Methods in Enzymology, ed. P. Sidney, K. Colomic, and O. Nathan, 121-126. New York: Academic Press.
    • (1984) Methods in Enzymology , pp. 121-126
    • Aebi, H.1
  • 5
    • 84874757737 scopus 로고
    • Microsomal metabolism of acrylonitrile in liver and rat brain
    • ed. Snyder, Parke, Jollow, Gibson, and Witmer. New York: Plenum
    • Ahmed, A. E., and Abreu, M. E, 1982. Microsomal metabolism of acrylonitrile in liver and rat brain. In Biological Reactive Intermediates, II: Part B. ed. Snyder, Parke, Jollow, Gibson, and Witmer, 1220-1244. New York: Plenum.
    • (1982) Biological Reactive Intermediates, II: Part B , pp. 1220-1244
    • Ahmed, A.E.1    Abreu, M.E.2
  • 6
    • 0020314248 scopus 로고
    • Comparative toxicities of aliphatic nitriles
    • Ahmed, A. E., and Farooqui, M. Y. H. 1982. Comparative toxicities of aliphatic nitriles. Toxicol. Lett. 12:157.
    • (1982) Toxicol. Lett. , vol.12 , pp. 157
    • Ahmed, A.E.1    Farooqui, M.Y.H.2
  • 7
    • 0021690342 scopus 로고
    • Molecular interaction of acrylonitrile in target sites
    • Ahmed, A. E., and Farooqui, M. Y. H. 1984. Molecular interaction of acrylonitrile in target sites. Arch. Toxicol. 7:405-406.
    • (1984) Arch. Toxicol. , vol.7 , pp. 405-406
    • Ahmed, A.E.1    Farooqui, M.Y.H.2
  • 8
    • 84874758213 scopus 로고    scopus 로고
    • Chloroacetonitrile (CAN) induces glutathione depletion and 8-hydroxylation of guanine bases in rat gastric mucosa
    • Ahmed, A. E., Jacob, S., and Nouraldeen, A. M. 1998. Chloroacetonitrile (CAN) induces glutathione depletion and 8-hydroxylation of guanine bases in rat gastric mucosa. J. Biol. Chem. Mol. Toxicol. 13:1-8.
    • (1998) J. Biol. Chem. Mol. Toxicol. , vol.13 , pp. 1-8
    • Ahmed, A.E.1    Jacob, S.2    Nouraldeen, A.M.3
  • 9
    • 0022272493 scopus 로고
    • Determination of glutathione and glutathione disulfide in biological samples
    • Anderson, M. E. 1985. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 113:548-555.
    • (1985) Methods Enzymol. , vol.113 , pp. 548-555
    • Anderson, M.E.1
  • 10
    • 0031947121 scopus 로고    scopus 로고
    • Astrocytes as mediators of immune and inflammatory responses in the CNS
    • Aschner, M. 1998. Astrocytes as mediators of immune and inflammatory responses in the CNS. Neurotoxicology 19:269-281.
    • (1998) Neurotoxicology , vol.19 , pp. 269-281
    • Aschner, M.1
  • 11
    • 0029900295 scopus 로고    scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston: The tumor necrosis factor legend and receptor families
    • Bazzoni, F., and Beutler, B. 1996. Seminars in medicine of the Beth Israel Hospital, Boston: The tumor necrosis factor legend and receptor families. N. Engl. J. Med. 334:1717-1725.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1717-1725
    • Bazzoni, F.1    Beutler, B.2
  • 12
    • 10544232621 scopus 로고    scopus 로고
    • Acrylonitrile potentiates oxidative stress in rat alveolar macrophages
    • Bhooma, T., and Venkataprasad, N. 1997, Acrylonitrile potentiates oxidative stress in rat alveolar macrophages. Bull. Environ. Contam. Toxicol. 58:71-78.
    • (1997) Bull. Environ. Contam. Toxicol. , vol.58 , pp. 71-78
    • Bhooma, T.1    Venkataprasad, N.2
  • 13
    • 0022641697 scopus 로고
    • Primary brain tumors in Fischer 344 rats chronically exposed to acrylonitrile in the drinking water
    • Bigner, D. D., Bigner, S. H., Burger, P. C., Shellburne, J. D., and Friedman, H. S. 1986. Primary brain tumors in Fischer 344 rats chronically exposed to acrylonitrile in the drinking water. Food Chem. Toxicol. 24:129-137.
    • (1986) Food Chem. Toxicol. , vol.24 , pp. 129-137
    • Bigner, D.D.1    Bigner, S.H.2    Burger, P.C.3    Shellburne, J.D.4    Friedman, H.S.5
  • 14
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 15
    • 0002679369 scopus 로고
    • Oxygen radicals and Parkinson's disease
    • ed. B. Haliwell. New York: Acadamic Press
    • Cohen, G. 1988. Oxygen radicals and Parkinson's disease. In Oxygen Radical and Tissue Injury, ed. B. Haliwell, 445-449. New York: Acadamic Press.
    • (1988) Oxygen Radical and Tissue Injury , pp. 445-449
    • Cohen, G.1
  • 16
    • 0002865475 scopus 로고    scopus 로고
    • Glutathione in the brain: Disorders of glutathione metabolism
    • ed. R. N. Rosenberg, S. B. Prusiner, S. Dimauro, R. L. Barchi, and L. M. Kunk. New York: Raven Press
    • Cooper, A. J. L. 1997. Glutathione in the brain: disorders of glutathione metabolism. In The Molecular and Genetic Basis of Neurologic Disease, ed. R. N. Rosenberg, S. B. Prusiner, S. Dimauro, R. L. Barchi, and L. M. Kunk, 1195-1230. New York: Raven Press.
    • (1997) The Molecular and Genetic Basis of Neurologic Disease , pp. 1195-1230
    • Cooper, A.J.L.1
  • 17
    • 0030792637 scopus 로고    scopus 로고
    • Multiple roles of glutathione in the central nervous system
    • Cooper, A. J. L., and Kristal, B. S. 1997. Multiple roles of glutathione in the central nervous system. Biol. Chem. 378:793-802.
    • (1997) Biol. Chem. , vol.378 , pp. 793-802
    • Cooper, A.J.L.1    Kristal, B.S.2
  • 18
    • 0029836312 scopus 로고    scopus 로고
    • Glutathione content as an indicator for the presence of metabolic pathways of amino acids in astroglial cultures
    • Dringen, R., and Hamprecht, B. 1996. Glutathione content as an indicator for the presence of metabolic pathways of amino acids in astroglial cultures. J. Neurochem. 67:1375-1382.
    • (1996) J. Neurochem. , vol.67 , pp. 1375-1382
    • Dringen, R.1    Hamprecht, B.2
  • 19
    • 0041397789 scopus 로고    scopus 로고
    • Glutathione metabolism of brain cells: Metabolic interaction between astrocytes and neurons
    • Dringen, R., Kranich, O., Pfeiffer, B., and Hamprecht, B. 1998. Glutathione metabolism of brain cells: metabolic interaction between astrocytes and neurons. J. Neurochem. 71:S6A.
    • (1998) J. Neurochem. , vol.71
    • Dringen, R.1    Kranich, O.2    Pfeiffer, B.3    Hamprecht, B.4
  • 20
    • 0034129994 scopus 로고    scopus 로고
    • Sodium thiosulfate protects against acrylonitrile-induced elevation of glial fibrillary acidic protein levels by replinishing glutathione
    • Enongene, E. N., Sun, P. N., and Mehtha, C. S. 2001. Sodium thiosulfate protects against acrylonitrile-induced elevation of glial fibrillary acidic protein levels by replinishing glutathione. Cell Biol. Toxicol. 8:153-161.
    • (2001) Cell Biol. Toxicol. , vol.8 , pp. 153-161
    • Enongene, E.N.1    Sun, P.N.2    Mehtha, C.S.3
  • 21
    • 0025045198 scopus 로고
    • The role of 8-hydroxyguanine in carcinogenesis
    • Floyd, R. A. 1990. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis 11:1447-1450.
    • (1990) Carcinogenesis , vol.11 , pp. 1447-1450
    • Floyd, R.A.1
  • 22
    • 0027218776 scopus 로고
    • Methods used for analysis of environmentally damaged nucleic acids
    • Frenkel, K., and Klein, C. B. 1993. Methods used for analysis of environmentally damaged nucleic acids. J. Chromatogr. 618:289-314.
    • (1993) J. Chromatogr. , vol.618 , pp. 289-314
    • Frenkel, K.1    Klein, C.B.2
  • 23
    • 0020585252 scopus 로고
    • Metabolism of acrylonitrile by isolated rat hepatocytes
    • Geiger, L. E., Hogy, L. L., and Guengerich, F. P. 1984. Metabolism of acrylonitrile by isolated rat hepatocytes. Cancer Res. 43:3080-3087.
    • (1984) Cancer Res. , vol.43 , pp. 3080-3087
    • Geiger, L.E.1    Hogy, L.L.2    Guengerich, F.P.3
  • 24
    • 0022000828 scopus 로고
    • Acrylonitrile-induced gastric mucosal necrosis: Role of gastric glutathione
    • Ghanayem, B. I., Boor, P. J., and Ahmed, A. E. 1985. Acrylonitrile-induced gastric mucosal necrosis: role of gastric glutathione. J. Pharmacol. Exp. Ther. 232:570-577.
    • (1985) J. Pharmacol. Exp. Ther. , vol.232 , pp. 570-577
    • Ghanayem, B.I.1    Boor, P.J.2    Ahmed, A.E.3
  • 26
    • 0033217887 scopus 로고    scopus 로고
    • The assessment of the immune status of women exposed to the action of radiation and chemical factors
    • Grebeniuk, A. N., Bezhenar, V. F., Antushevich, A. E., and Liutov, R. V. 1999. The assessment of the immune status of women exposed to the action of radiation and chemical factors. Voen. Med. Zh. 320:49-54.
    • (1999) Voen. Med. Zh. , vol.320 , pp. 49-54
    • Grebeniuk, A.N.1    Bezhenar, V.F.2    Antushevich, A.E.3    Liutov, R.V.4
  • 27
    • 0029090167 scopus 로고
    • Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
    • Goossens, V., Grooten, J., De Vos, K., and Fiers, W. 1995. Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity. Proc. Natl. Acad. Sci. U S A 92:8115-8119.
    • (1995) Proc. Natl. Acad. Sci. U S A , vol.92 , pp. 8115-8119
    • Goossens, V.1    Grooten, J.2    De Vos, K.3    Fiers, W.4
  • 28
    • 0019825946 scopus 로고
    • In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione and irreversible binding to proteins and nucleic acids
    • Guengerich, F. P., Geiger, L. E., Hogy, L. L., and Wright, P. L. 1981. In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione and irreversible binding to proteins and nucleic acids. Cancer Res. 41:4925-4933.
    • (1981) Cancer Res. , vol.41 , pp. 4925-4933
    • Guengerich, F.P.1    Geiger, L.E.2    Hogy, L.L.3    Wright, P.L.4
  • 33
    • 0032446001 scopus 로고    scopus 로고
    • Induction of oxidative stress in rat brain by acrylonitrile (ACN)
    • Jiang, J., Xu, Y., and Klaunig, J. E. 1998. Induction of oxidative stress in rat brain by acrylonitrile (ACN). Toxicol. Sci. 46(2):333-341.
    • (1998) Toxicol. Sci. , vol.46 , Issue.2 , pp. 333-341
    • Jiang, J.1    Xu, Y.2    Klaunig, J.E.3
  • 34
    • 0037166695 scopus 로고    scopus 로고
    • Chronic toxicity and oncogenic dose-response effects of lifetime oral acrylonitrile exposure on Fischer 344 rats
    • Johannsen, F. R., and Levinskas, G. J. 2002. Chronic toxicity and oncogenic dose-response effects of lifetime oral acrylonitrile exposure on Fischer 344 rats. Toxicol. Lett. 132:221-247.
    • (2002) Toxicol. Lett. , vol.132 , pp. 221-247
    • Johannsen, F.R.1    Levinskas, G.J.2
  • 36
    • 0032839210 scopus 로고    scopus 로고
    • Induction of oxidative stress and oxidative damage in rat glial cells by acrylonitrile
    • Kamendulis, L. M., Jiang, J., Xu, Y., and Klaunig, J. E. 1999b. Induction of oxidative stress and oxidative damage in rat glial cells by acrylonitrile. Carcinogenesis 20:1555-1560.
    • (1999) Carcinogenesis , vol.20 , pp. 1555-1560
    • Kamendulis, L.M.1    Jiang, J.2    Xu, Y.3    Klaunig, J.E.4
  • 37
    • 0021636613 scopus 로고
    • Role of oxygen radicals in tumor promotion
    • Kensler, T. W., and Thrush, M. A. 1986. Role of oxygen radicals in tumor promotion. Environ. Mutagen. 6:593-616.
    • (1986) Environ. Mutagen. , vol.6 , pp. 593-616
    • Kensler, T.W.1    Thrush, M.A.2
  • 40
    • 0029013291 scopus 로고
    • Trimethyltin increases interleukin (IL)-α, IL-6 and tumor necrosis factor α mRNA levels in rat hippocamus
    • Maier, W. E., Brown, H. W., Tilson, H. A., Luster, M. I., and Harry, G. J. 1995. Trimethyltin increases interleukin (IL)-α, IL-6 and tumor necrosis factor α mRNA levels in rat hippocamus. J. Neuroimmunol. 59:65-75.
    • (1995) J. Neuroimmunol. , vol.59 , pp. 65-75
    • Maier, W.E.1    Brown, H.W.2    Tilson, H.A.3    Luster, M.I.4    Harry, G.J.5
  • 41
    • 0027976087 scopus 로고
    • Vitamin E, ascorbate, glutathione, glutathione disulfide and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: Evidence that astrocytes play an important role in antioxidative process in the brain
    • Makar, T. K., Nedergaard, M., Preuss, A., Gelbard, A. S., Perumal, A. S., and Cooper, A. J. L. 1994. Vitamin E, ascorbate, glutathione, glutathione disulfide and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative process in the brain. J. Neurochem. 62:45-53.
    • (1994) J. Neurochem. , vol.62 , pp. 45-53
    • Makar, T.K.1    Nedergaard, M.2    Preuss, A.3    Gelbard, A.S.4    Perumal, A.S.5    Cooper, A.J.L.6
  • 42
    • 0017586264 scopus 로고
    • Carcinogenecity bioassays on rats of acrylonitrile administered by inhalation and by ingestion
    • Maltoni, C., Ciliberti, A., and Di Maio, V. 1977. Carcinogenecity bioassays on rats of acrylonitrile administered by inhalation and by ingestion. Med. Lav. 68:401-411.
    • (1977) Med. Lav. , vol.68 , pp. 401-411
    • Maltoni, C.1    Ciliberti, A.2    Di Maio, V.3
  • 43
    • 0027296234 scopus 로고
    • Free radical induction in the brain and liver by products of toluene catabolism
    • Mattia, C. J., Adams, J. D., and Bondy, S. C. 1993. Free radical induction in the brain and liver by products of toluene catabolism. Biochem. Pharmacol. 46:103-110.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 103-110
    • Mattia, C.J.1    Adams, J.D.2    Bondy, S.C.3
  • 44
    • 0000311848 scopus 로고
    • Glutathione
    • ed. I. M. Arias, W. B. Jakoby, H. Popper, D. Schacter, and D. A. Sjafrotz. New York: Raven Press
    • Meister, A. 1988. Glutathione. In The Liver: Biology and Pathobiology, ed. I. M. Arias, W. B. Jakoby, H. Popper, D. Schacter, and D. A. Sjafrotz, 401-417. New York: Raven Press.
    • (1988) The Liver: Biology and Pathobiology , pp. 401-417
    • Meister, A.1
  • 47
    • 0009461282 scopus 로고
    • Results of chronic toxicity and oncogenicity study in rats following 24 months of acrylonitrile ingestion exposure
    • Quast, J. F., Gushow, T. S., Shuetz, T. J., Balmer, M. F., Park, C. N., and Mc Kenna, M. J. 1982. Results of chronic toxicity and oncogenicity study in rats following 24 months of acrylonitrile ingestion exposure. Toxicologist 2:63.
    • (1982) Toxicologist , vol.2 , pp. 63
    • Quast, J.F.1    Gushow, T.S.2    Shuetz, T.J.3    Balmer, M.F.4    Park, C.N.5    Mc Kenna, M.J.6
  • 48
    • 0037166696 scopus 로고    scopus 로고
    • Two-year toxicity study and oncogenicity study with acrylonitrile incorporated in the drinking water of rats
    • Quast, J. F. 2002. Two-year toxicity study and oncogenicity study with acrylonitrile incorporated in the drinking water of rats. Toxicol. Lett. 132:153-196.
    • (2002) Toxicol. Lett. , vol.132 , pp. 153-196
    • Quast, J.F.1
  • 49
    • 0024324666 scopus 로고
    • Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons
    • Raps, S. P., Lai, J. C., Hertz, L., and Cooper, A. J. 1989. Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons. Brain Res. 493:398-401.
    • (1989) Brain Res. , vol.493 , pp. 398-401
    • Raps, S.P.1    Lai, J.C.2    Hertz, L.3    Cooper, A.J.4
  • 50
    • 0024541481 scopus 로고
    • Effects of prolonged ethanol exposure on the glial fibrillary acidic protein-containing intermediate filaments of astrocytes in primary culture: A quantitative immunofluorescence and immunogold electron microscopic study
    • Renau-Piqueras, J., Zaragoza, R., Depaz, P., Baguena-Cervellera, R., Megias, L., and Gurri, C. 1988. Effects of prolonged ethanol exposure on the glial fibrillary acidic protein-containing intermediate filaments of astrocytes in primary culture: a quantitative immunofluorescence and immunogold electron microscopic study. J. Histochem. 37:229-240.
    • (1988) J. Histochem. , vol.37 , pp. 229-240
    • Renau-Piqueras, J.1    Zaragoza, R.2    Depaz, P.3    Baguena-Cervellera, R.4    Megias, L.5    Gurri, C.6
  • 51
    • 0032579829 scopus 로고    scopus 로고
    • An in vitro model for analysis of oxidative death in primary mouse astrocytes
    • Robb, S. J., and Connor, J. R. 1998. An in vitro model for analysis of oxidative death in primary mouse astrocytes. Brain Res. 788:125-132.
    • (1998) Brain Res. , vol.788 , pp. 125-132
    • Robb, S.J.1    Connor, J.R.2
  • 53
    • 0017864441 scopus 로고
    • Superoxide dismutase and glutathione peroxidase activities in rat brain
    • Savolainen, H. 1978. Superoxide dismutase and glutathione peroxidase activities in rat brain. Res. Commun. Chem. Pathol. Pharmacol. 21:173-176.
    • (1978) Res. Commun. Chem. Pathol. Pharmacol. , vol.21 , pp. 173-176
    • Savolainen, H.1
  • 55
    • 0026713818 scopus 로고
    • Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial function
    • Schulze-Osthoff, K., Bakker, A. C., Vanhaesebrook, B., and Beyaert, R. 1992. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial function. J. Biol. Chem. 267:5317-5323.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5317-5323
    • Schulze-Osthoff, K.1    Bakker, A.C.2    Vanhaesebrook, B.3    Beyaert, R.4
  • 56
    • 0025973702 scopus 로고
    • Assay for 8-hydroxy-2′-deoxyguanosine: A biomarker of in vivo oxidative DNA damage
    • Shigenaga, M. K., and Ames, B. N. 1991. Assay for 8-hydroxy-2′ -deoxyguanosine: a biomarker of in vivo oxidative DNA damage. Free Radic. Biol. Med. 10:211-216.
    • (1991) Free Radic. Biol. Med. , vol.10 , pp. 211-216
    • Shigenaga, M.K.1    Ames, B.N.2
  • 58
    • 0029808476 scopus 로고    scopus 로고
    • Induction of cytochrome P450 2E1 expression in rat and gerbil astrocytes by inflammatory factors and ischemic injury
    • Tindberg, N., Baldwin, H. A., Cross, A. J., and Ingelman-Sundberg M. 1996. Induction of cytochrome P450 2E1 expression in rat and gerbil astrocytes by inflammatory factors and ischemic injury. Molec. Pharmacol. 50:1065-1072.
    • (1996) Molec. Pharmacol. , vol.50 , pp. 1065-1072
    • Tindberg, N.1    Baldwin, H.A.2    Cross, A.J.3    Ingelman-Sundberg, M.4
  • 59
    • 0033763824 scopus 로고    scopus 로고
    • Species difference in acrylonitrile metabolism and toxicity between experimental animals and humans based on observations in human accidental poisonings
    • Thier, R., Lewater, J., and Bolt, H. M. 2001. Species difference in acrylonitrile metabolism and toxicity between experimental animals and humans based on observations in human accidental poisonings. Arch. Toxicol. 74:184-189.
    • (2001) Arch. Toxicol. , vol.74 , pp. 184-189
    • Thier, R.1    Lewater, J.2    Bolt, H.M.3
  • 60
    • 0029098713 scopus 로고
    • Role of glutathioine redox cycle in TNF-alpha mediated endothelial cell dysfunction
    • Toborek, M., Barger, S. W., Mattson, M. P., McClain, C. J., and Hennig, B. 1995. Role of glutathioine redox cycle in TNF-alpha mediated endothelial cell dysfunction. Atherosclerosis 117:179-183.
    • (1995) Atherosclerosis , vol.117 , pp. 179-183
    • Toborek, M.1    Barger, S.W.2    Mattson, M.P.3    McClain, C.J.4    Hennig, B.5
  • 61
    • 0027269725 scopus 로고
    • Kinetic study of the cytotoxic effect of L-sacrin, a ribosome-inactivating protein from Aspergillus giganteus, on tumor cell lines: Protein biosynthesis inhibition and cell binding
    • Turnay, J., Olmo, N., Jimenez, A., Lizarbe, M. A., and Gavilanes, J. G. 1993. Kinetic study of the cytotoxic effect of L-sacrin, a ribosome-inactivating protein from Aspergillus giganteus, on tumor cell lines: protein biosynthesis inhibition and cell binding. Molec. Cell Biochem. 122:39-47.
    • (1993) Molec. Cell Biochem. , vol.122 , pp. 39-47
    • Turnay, J.1    Olmo, N.2    Jimenez, A.3    Lizarbe, M.A.4    Gavilanes, J.G.5
  • 62
    • 0033053539 scopus 로고    scopus 로고
    • Effect of environmental pollutants on the production of pro-inflammatory cytokines by normal human dermal keratinocytes
    • Ushio, H., Nohara, K., and Fujimaki, H. 1999. Effect of environmental pollutants on the production of pro-inflammatory cytokines by normal human dermal keratinocytes. Toxicol. Lett. 105:17-24.
    • (1999) Toxicol. Lett. , vol.105 , pp. 17-24
    • Ushio, H.1    Nohara, K.2    Fujimaki, H.3
  • 63
    • 0017722281 scopus 로고
    • Styrene and acrylonitrile-induced depression of hepatic non-protein sulfhydryl content in various rodent species
    • Vainio, H., and Makinen, A. 1977. Styrene and acrylonitrile-induced depression of hepatic non-protein sulfhydryl content in various rodent species. Res. Commun. Chem. Pharmacol. 17:115-124.
    • (1977) Res. Commun. Chem. Pharmacol. , vol.17 , pp. 115-124
    • Vainio, H.1    Makinen, A.2
  • 64
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • Vassalli, P. 1992. The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10:411-452.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 411-452
    • Vassalli, P.1
  • 67
    • 0024202127 scopus 로고
    • Induction of manganese superoxide dismutase by TNF-α: Possible protective mechanism
    • Wong, G. H., and Goeddel, D. V. 1988. Induction of manganese superoxide dismutase by TNF-α: possible protective mechanism. Science 242:941-944.
    • (1988) Science , vol.242 , pp. 941-944
    • Wong, G.H.1    Goeddel, D.V.2
  • 68
    • 0031845459 scopus 로고    scopus 로고
    • Toxicologic profile of acrylonitrile
    • Woutersen, R. A. 1998. Toxicologic profile of acrylonitrile. Scand. J. Work Environ. Health 24(suppl. 2):5-9.
    • (1998) Scand. J. Work Environ. Health , vol.24 , Issue.SUPPL. 2 , pp. 5-9
    • Woutersen, R.A.1
  • 69
    • 0033785749 scopus 로고    scopus 로고
    • Role of corticosterone in realization of immunesupressive effects in acute poisoning with toxic chemicals
    • Zabrodski, P. F., and Germanchuk, V. G. 2000. Role of corticosterone in realization of immunesupressive effects in acute poisoning with toxic chemicals. Bull. Exp. Biol. Med. 129:468-470.
    • (2000) Bull. Exp. Biol. Med. , vol.129 , pp. 468-470
    • Zabrodski, P.F.1    Germanchuk, V.G.2
  • 71
    • 0036300583 scopus 로고    scopus 로고
    • Mechanisms for the induction of oxidative stress in Syrian hamster embryo cells by acrylonitrile
    • Zhang, H., Kamendulis, L. M., Jiang, J., Xu, Y., and Klaunig, J. E. 2002. Mechanisms for the induction of oxidative stress in Syrian hamster embryo cells by acrylonitrile. Toxicol. Sci. 67:247-252.
    • (2002) Toxicol. Sci. , vol.67 , pp. 247-252
    • Zhang, H.1    Kamendulis, L.M.2    Jiang, J.3    Xu, Y.4    Klaunig, J.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.