Sodium thiosulfate protects against acrylonitrile-induced elevation of glial fibrillary acidic protein levels by replenishing glutathione

Environmental Toxicology and Pharmacology

Volumn 8, Issue 2, 2000, Pages 153-161

  Enongene, Evaristus N ^a   Sun, Pei N ^b   Mehta, Chander S ^b  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b TEXAS SOUTHERN UNIVERSITY   (United States)

Author keywords

Acrylonitrile; Brain; GFAP; GSH; Neurotoxicity; STS

Indexed keywords

ACRYLONITRILE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; GLUTATHIONE TRANSFERASE; SODIUM THIOSULFATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ASTROCYTOSIS; BRAIN INJURY; BRAIN PROTECTION; BRAIN REGION; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; TISSUE DISTRIBUTION;

EID: 0034129994     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1382-6689(00)00036-3     Document Type: Article

References (79)

1. Abreu A.E., Ahmed E.A. Metabolism of acrylonitrile to cyanide. In vitro studies. Drug Metab. Dispos. 8:1980;376-379.
2. Banerje S., Segal A. In vitro transformation of C3H/10T2 and NIH/3T3 cells by acrylonitrile and acrylamide. Cancer Lett. 32:1986;293-304.
3. Baus, D.K., Hsu, R.S., Neal, M.W., Santodonato, J., Sugatt, R.H., Bayard, S., Bayliss, D.L., Hiremath, C.B., Vaughn-Dellarco, V., 1983. Health Assoc.doc. Acrylonitrile report no. EPA-600/8-82-007F, US EPA, RTP, NC.
4. Benz F.W., Nerland D.E., Pierce W.M., Babiuk C. Acute acrylonitrile toxicity: studies on the mechanism of the antidotal effects of D- and L-cysteine, and their N-acetyl derivatives in rat. Toxicol. Appl. Pharmacol. 102:1990;142-150.
5. Benz F.W., Nerland D.E., Corbett D., Li J. Biological markers of acrylonitrile intoxication in rats as a function of dose and time. Fundam. Appl. Toxicol. 36:1997;141-148.
6. Benz F.W., Nerland D.E., Li. J., Corbett D. Dose dependence of covalent binding of ACN to tissue protein and globin in rats. Fundam. Appl. Toxicol. 36:1997;149-156.
7. Bigner D.D., Bidgner S.H., Burger P.C., Shelburne J.D., Friedman H.S. Primary Brain Tumors in Fisher 344 rats chronically exposed to acrylonitrile in their drinking water. Food. Chem. Toxicol. 24(2):1986;129-137.
8. Byrd C.D., Fowler K.W., Hicks R.D., Lovette M.E., Borgerding M.F. Isotope dilution gas chromatography mass spectrometry in the determination of benzene, toluene, styrene and acrylonitrile in main stream cigarette smoke. J. Chromatogr. 503:1990;359-360.
9. Cappellini M.D., Sampietro M., Toniolo D., Carandina G., Martinez D.M.F., Tavazzi D., Fiorelli G. G6PDH Ferrara 1 has the same two mutations as G6PDH A(-) but a distinct biochemical phenotype. Hum. Genet. 93(2):1994;139-142.
10. Chauncy T.R., Westley J. The catalytic mechanism of yeast thiosulfate reductase. J. Biol. Chem. 258(24):1983;15037-15045.
11. Production by the US chemical industry. Chem. Eng. News. 73:1995;38-39.
12. Cheng J.L., Walrath J., O'Berg M.T., Burke C.A., Pell S. Cancer incidence and mortality among workers exposed to acrylonitrile. Am. J. Ind. Med. 11:1987;157-163.
13. Dorman D.C., Struve M.F., Ritzman T.K., Owens J.G., Morgan K.T. Acrylonitrile-induced cytotoxicity in primary rat neural cell cultures. In Vitro Toxicol. 9(4):1996;361-371.
14. Drukarch B., Schepers E., Jongenden L.A.M., Stoff J.C., Langeveld C.H. Astrocytes-mediated enhancement of neuronal survival is abolished by glutathione deficiency. Brain Res. 770:1997;123-130.
15. El-Fawal H.A.N., Gong Z., Little A.R., Evans H.A.L. Exposure to methylmercury results in serum antibodies to neurotypic and gliotypic proteins. Neurotoxicology. 17:1996;267-276.
16. Ellman G.L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82:1959;70-77.
17. Eng V., Perlmann P. ELISA. Immuno. Chem. 8:1971;871-879.
18. Preliminary draft list of categories and sub-categories under section 112 of the Clean Air Act. Fed. Reg. 56:1991;28548-28557.
19. Farooqui M.Y.H., Mumtaz M.M. Toxicology of methacrylonitrile. Toxicology. 65:1991;239-250.
20. Felter S.P., Dollarhide J.S. Acrylonitrile: a reevaluation of the database to support an inhalation cancer risk assessment. Respir. Toxicol. Pharmacol. 26:1997;281-287.
21. Fennell T.R., Summer S.C.J. Identification of metabolites of carcinogens by 13C-NMR spectroscopy. Drug Metabol. Rev. 26(1&2):1994;469-481.
22. Ghanayem B.I., Boor P.J., Ahmed A.E. Acrylonitrile-induced gastric mucosal necrosis: role of gastric glutathione. Pharmacol. Exper. Therap. 232:1985;570-577.
23. Glowinski J., Iversen L.L. Regional studies of catecholamines in the rat brain. I. J. Neurochem. 13:1966;655-669.
24. Guengerich F.P., Geiger L.E., Hogg L.L., Wright P.L. In vitro metabolism of acrylonitrile to 2-cyano ethylene oxide, reaction with glutathione and irreversible binding to proteins and nucleic acids. Cancer Res. 41:1981;4925-4933.
25. Guengerich F.P., Geiger L.E., Hogg L.L., Inskeep P.B., Liebler D.C. Metabolism and covalent binding of di halo alkanes, vinyl halides and acrylonitriles. IARC Sci. Publ. 70:1986;255-260.
26. Gut I., Nerudova J., Frantik E., Mirejovska E., Halusa R. Acrylonitrile inhalation in rats. Effects on intermediary metabolism. J. Hyg. Epidemiol. Microbol. Immunol. 28:1984;369-376.
27. Hashimoto K., Kanai R. Studies on the toxicology of ACN: metabolism, mode of action and therapy. Ind. Health. 3:1965;30-40.
28. Hogg L.L., Guengerich F.P. In vitro interaction of acrylonitrile and 2-cyanoethylene oxide with DNA in rats. Cancer Res. 46:1986;3932-3938.
29. Huang J., Philbert M.A. Distribution of glutathione and glutathione related enzymes in mitochondria and cytosol of cultured cerebellar astrocytes and granule. Brain Res. 680:1995;16-22.
30. IARC monographs on the evaluation of carcinogenic risk of chemical to humans. IARC Monogr. 4(Suppl.):1982;1-29.
31. Igbal M., Sharma S.D., Rezazadeh H., Hassan N., Abdulla M., Athar M. Glutathione metabolizing enzymes and oxidative stress in ferric nitrilotriacetate mediated hepatic injury. Redox. Rep. 2(6):1996;385-391.
32. Ivanov V., Ralier J., Lauweys R. Lipid-peroxidation in acrylonitrile treated rats, evidenced by elevated ethane production. J. Appl. Toxicol. 9:1989;353-358.
33. Ivanov V., Hashimoto K., Inomata K., Kawai I., Mizumuma K., Klimatskaya L. Biological monitoring of acrylonitrile exposure through a new analytical approach to hemoglobin and plasma protein adducts and urinary metabolites in rats and humans. Int. Arch. Occup. Environ. Health. 65:1993;S103-S106.
34. Jiang J., Xu Y., Klauning J.E. Induction of oxidative stress in rat brain by acrylonitrile. Toxicol. Sci. 46:1998;333-341.
35. Kedderis G.L., Batra R., Koop D.R. Epoxidation of acrylonitrile by rat and human cytochrome. P450. Chem. Res. Toxicol. 6(6):1993;867-871.
36. Kedderis G.L., Sumner G.L.J., Held S.D., Batra R., Tunner M.J. Jr, Roberts A.E., Fennell T.R. Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice. Toxicol. Appl. Pharmacol. 120:1993;288-297.
37. Kemper R.A., Myers S., Hurst H.E. Detoxification of vinyl carbamate epoxide by glutathione: evidence for participation of glutathione S-transferase in metabolism of ethylcarbamate. Toxicol. Appl. Pharm. 135:1995;110-118.
38. Koerselman W., Vande-Graaf M. Acrylonitrile a suspected human carcinogen. Int. Arch. Occup. Environ. Health. 54:1984;317-324.
39. Kopecky J., Gut I., Nerudova J., Zachardova D., Holecek V. Two routes of acrylonitrile metabolism. J. Hyg. Epidemiol. Microbiol. Immunol. 24:1980;356-362.
40. Kozumbo W., Agal S., Koren H.S. Breakage and binding of DNA by reaction products of hypochlorous acid with aniline, 1-naphthylamine, or 1-naphthol. Toxicol. Appl. Pharmacol. 115:1992;107-115.
41. Kutsenko S.A., Shilov V.V. Dynamics of the activity of cytochrome oxidase and GSH in tissues of rats poisoned with KCN and nitriles. Toxicologist. 32:1991;72-74.
42. Kyrklund T., Haglid K.G. Brain lipid changes after organic solvent exposure. Ups. J. Med. Sci. Suppl. 48:1990;267-277.
43. Maker H.S. Glutathione. Lajtha A. Handbook of Neurochemistry, 2nd ed., vol. 3. Metabolism in the Nervous System. 1983;607-631 Plenum, New York.
44. Maltoni C., Giliberti A., Cotti G., Perino G. Long term carcinogenicity bioassays on acrylonitrile administered by inhalation and by ingestion to Sprague-Dawley rats. Ann. New York Acad. Sci. 534:1988;179-202.
45. 100 autoantibodies in aging brain, Alzheimer's disease and vascular dementia. J. Neuroimmunol. 57:1995;165-170.
46. Mehta C.S. Antidotal effects of sodium thiosulfate in mice exposed to acrylonitrile. Res. Commun. Mol. Pathol. Pharmacol. 87:1995;155-165.
47. Mehta C.S., Sun P.N., Gammage N., Zikarge A., Mumtaz M. Astudy of glial fibrillary acidic protein as a neurobiomarker following a single oral exposure to either toluene, or trichloroethylene in rats. Toxicologist. 30:1996;260.
48. Mehta C.S., Sun P.N., Hollomon M., Enongene E., Mumtaz M. Elevation of glial fibrillary acidic protein in the rat CNS: 13 week toluene and trichloroethylene oral exposure studies. Toxicologist. 28:1997;80.
49. Meister A. Glutathione deficiency produced by inhibition of its synthesis and its reversal; application in research and therapy. Pharmacol. Ther. 51:1991;55-194.
50. Murray F.J., Schwetz B.A., Nitscke K.D., John J.A., Morris J.M., Gehring P.J. Teratogenicity of acrylonitrile given rats by gavage or by inhalation. Food Cosmet. Toxicol. 16:1978;547-551.
51. Nakamura K., Takeda M., Tanaka J., Kato Y., Nishinuma K., Nishimura T. Glial fibrillary acidic protein stimulates proliferation and immunoglobulin synthesis of lymphocytes from alzheimer's disease patients. Methods Fund. Exp. Clin. Pharmacol. 14:1992;141-149.
52. National Institute for Occupational Safety and Health (NIOSH), 1978. Current Intelligence Bulletin, 1, March NIOSH Cincinnati, OH.
53. Niknahad H., O'Brien P.J. Antidotal effect of Dihydroxyacetone against cyanide toxicity in vivo. Toxicol. Appl. Pharmacol. 138:1996;186-191.
54. O'Berg M.T. Epidemiologic study of workers exposed to acrylonitrile. J. Occup. Med. 22:1980;245-252.
55. O'Callaghan J.P. Quantification of GFAP: comparison of slot-immunobinding assays with a novel sandwich Elisa. Neurotoxicol. Teratol. 13:1991;275-281.
56. O'Callaghan J.P., Miller D.B. Acute exposure of neonatal rat to trimethyltin (TMT) results in persistent changes in neurotypic and gliotypic proteins. J. Pharmacol. Exp. Ther. 244:1988;368-378.
57. O'Callaghan J.P., Jensen K.F. Assessment of neurotoxicity: use of glial fibrillary acidic protein as a biomarker. Biomed. Environ. Sci. J. 4:1991;197-206.
58. O'Callaghan J.P., Jensen K.F., Miller D.B. Quantitative aspects of drugs and toxicant-induced astrogliosis. Neurochem. Int. 26:1995;115-124.
59. Occupational Safety and Health Administration (OSHA), 1978. Occupational exposure to acrylonitrile (Vinyl cyanide). Proposed standard and notice of hearing. Fed. Reg. 43, 2586. Final standard ibid. 43, 45762.
60. Occupational Safety and Health Administration (OSHA), 1978. Occupational exposure to acrylonitrile (Vinyl cyanide). Proposed standard and notice of hearing. Fed. Reg. 43, 2586. Final standard ibid. 43, 45762.
61. Page B.D. Determination of acrylonitrile in foods by head space gas chromatography with nitrogen sensitive detection. Collaborative study. J. Assoc. Anal. Chem. 68:1985;776-782.
62. Page N.P., Cook B. Assessment of risk from exposure to acrylonitrile: the general approach used by a consultant. Sci. Total Environ. 99:1990;307-317.
63. Quast, J.F., Wade, C.E., Humiston, C.G., Carreon, R.M., Hermann, E.A., Park, C.N., Schwetz, B.A., 1980. A two-year toxicity and oncogenicity study with acrylonitrile incorporated in the drinking water of rats. Prepared by the Toxicology Research Laboratory, Health and Environmental Sciences, Dow Chemical USA, Midland, MI, for the Chemical Manufacturers Association, Washington, DC [Available from CMA, Washington, DC].
64. Raps S.P., Lai J.C.K., Hertz L., Cooper A.J.L. Glutathione is present in high concentration in cultural astrocytes but not in cultural neurons. Brain Res. 493:1989;398-440.
65. Ravindranath V., Bangalore R.S., Hindupur K.A. Low glutathione levels in brain regions of aged rats. Neurosci. Lett. 101:1989;187-190.
66. Recio L., Skopek T.R. Mutagenecity of Acylonitrile and its metabolite. 2-Cyanoethylene oxide in humans lymphoblast in vitro. Mutat. Res. 206:1988;197-305.
67. Robbins K.T., Stroniolo A.M., Kerber C., Vicario D., Seagren M., Hanchett C., Los G., Howell S.B. Phase I study of highly selective supradose cisplatin, infusions for advanced head and neck cancer. J. Clin. Oncol. 12:1994;2113-2121.
68. Roberts A.E., Kidderis G.L., Turner M.J., Ricket D.E., Swenberg J.A. Specie comparison of ACN expoxidation by microsome from mice, rats, and humans: relationship to epoxide concentration in rat and mouse blood. Carcinogenesis. 12(3):1991;401-404.
69. Smith P.K., Krohn R.I., Hermanson G.T., Maillia A.K., Gartner F.H., Provezano M.D., Fujimoto E.K., Goeke N.M., Olson B.J., Klenk D.C. Measurement of protein using Bicinchoninic acid. Annal. Biochem. 150:1985;76-85.
70. Sumner S.C.J., Selvara L., Nauhaus S.K., Fennell T.R. Urinary metabolites from F344 rats and B6C3F1 mice coadministered acrylamide and acylonitrile for 15 days. Chem. Res. Toxicol. 10:1997;1152-1160.
71. Szabo S., Bailey K.A., Boor P.J., Jeager R.J. Acrylonitrile and tissue glutathione: differential effect of acute and chronic interactions. Biochem. Biophys. Res. Commun. 79:1977;32-37.
72. Tiffany-Castiglioni E. Cell culture models in neuronal and glial cells. Neurotoxicology. 14:1993;513-536.
73. Tiffany-Castiglioni E., Sierra E.M., Rowles T.K. Lead toxicity in neuroglia. Neurotoxicology. 10:1991;417-444.
74. Trenga C.A., Kunkel D.D., Eaton D.L., Costa L.G. Effects of styrene oxide on rat brain glutathione. Neurotoxicology. 12:1991;165-178.
75. Usha S., Ahmed A. Intestinal toxicity of acrylonitrile: in vitro metabolism by intestinal cytochrome P450 2E1. Toxicol. Appl. Pharmacol. 135:1995;1-8.
76. Venitt S., Bushell C.T., Osborne M. Mutagenicity of acrylonitrile cyano ethylene in E. coli. Mutation Res. 45:1977;283-288.
77. Yamamoto H. Protection against paraquat-induced toxicity with sulfite or thiosulfate in mice. Toxicology. 79:1993;37-43.
78. Yoshida T., GoldSmith S.K., Morgan T.E., Stone D.J., Finch C.E. Transcription supports age-related increase of GFAP gene expression in male rat brain. Neurosci. Lett. 215:1996;107-110.
79. Yu-Dah S., Chang S.Y., Ma C.P. The correlation of membranous glycoprotein Gp-170, cytoplasmic glutathione and glucose-6-phosphate dehydrogenase levels with multidrug resistance in transitional cell carcinoma cell lines of the urinary tract. J. Urol. (Baltimore). 157:1997;727-731.