Role of intracellular calcium mobilization and cell-density-dependent signaling in oxidative-stress-induced cytotoxicity in HaCaT keratinocytes

Journal of Investigative Dermatology

Volumn 121, Issue 1, 2003, Pages 88-95

  Bakondi, Edina ^a   Gönczi, Mónika ^a,b   Szabó, Éva ^c,d   Bai, Péter ^a   Pacher, Pál ^d   Gergely, Pál ^a   Kovács, László ^a,b   Hunyadi, János ^c   Szabó, Csaba ^d,e   Csernoch, László ^a,b,c   Virág, László ^a,c,d  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d INOTEK CORPORATION   (United States)

^e SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Apoptosis; Calcium signaling; Hydrogen peroxide; Necrosis; Peroxynitrous acid

Indexed keywords

CALCIUM ION; CASPASE; HYDROGEN PEROXIDE; LINSIDOMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXYNITRITE;

ARTICLE; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CELL DEATH; CELL DENSITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KERATINOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0041342103     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2003.12329.x     Document Type: Article

References (44)

1. Beckman JS, Koppenol WH: Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly. Am J Physiol 271 (5 Part 1):C1424-C1437, 1996
2. Berger NA, Sims JL, Catino DM, Berger SJ: Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: Studies in normal and DNA-repair defective cells. Princess Takamatsu Symp 13:219-226, 1983
3. Bíró T, Szabó I, Kovács L, Hunyadi J, Csernoch L: Distinct subpopulations in HaCaT cells as revealed by the characteristics of intracellular calcium release induced by phosphoinositide-coupled agonists. Arch Dermatol Res 290:270-276, 1998
4. Cotton SA, Herrick AL, Jayson MI, Freemont AJ: Endothelial expression of nitric oxide synthases and nitrotyrosine in systemic sclerosis skin. J Pathol 189:273-278, 1999
5. Csernoch L, Hunyadi J, Kovács L: Calcium release activated calcium entry in a human skin derived cell line. Exp Dermatol 9:200-205, 2000
6. Deliconstantinos G, Villiotou V, Stavrides JC: Increase of particulate nitric oxide synthase activity and peroxynitrite synthesis in UVB-irradiated keratinocyte membranes. Biochem J 320:997-1003, 1996
7. Filipovic DM, Meng X, Reeves WB: Inhibition of PARP prevents oxidant-induced necrosis but not apoptosis in LLC-PK1 cells. Am J Physiol 277:F428-F436, 1999
8. 2+ release from intracellular stores in cultured cerebral cortical neurons. J Neurochem 56:1075-1078, 1991
9. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450, 1985
10. Guidarelli A, Clementi E, Sciorati C, Cattabeni F, Cantoni O: Calcium-dependent mitochondrial formation of species mediating DNA single strand breakage in U937 cells exposed to sublethal concentrations of tert-butylhydroperoxide. J Pharmacol Exp Ther 283:66-74, 1997
11. Guidarelli A, Fiorani M, Cantoni O: Calcium-dependent mitochondrial formation of species promoting strand scission of genomic DNA in U937 cells exposed to tert-butylhydroperoxide: The role of arachidonic acid. Free Radic Res 33:477-487, 2000
12. Gutierrez-Martin Y, Martin-Romero FJ, Henao F, Gutierrez-Merino C: Synaptosomal plasma membrane Ca(2+) pump activity inhibition by repetitive micromolar ONOO(-) pulses. Free Radic Biol Med 32:46-55, 2002
13. Ha HC, Snyder SH: Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc Natl Acad Sci USA 96:13978-13982, 1999
14. Hattori Y, Nishigori C, Tanaka T, et al: 8-Hydroxy-2′-deoxyguanosine is increased in epidermal cells of hairless mice after chronic ultraviolet B exposure. J Invest Dermatol 107:733-737, 1996
15. Hamburg S, Visochek L, Maran N, et al: Fast signal-induced activation of poly (ADP-Ribose) polymearse: A novel downstream target of phospholipase C. J Cell Biol 150:293-307, 2000
16. 2+ chelation: Involvement of a common mechanism. Biochem Pharmacol 57:19-26, 1999
17. Lee JY, Kim YH, Koh JY: Protection by pyruvate against transient forebrain ischemia in rats. J Neurosci 21:RC171, 2001
18. 2 and NO stresses. Biochem J 364:349-359, 2002
19. Lerner LH, Qureshi AA, Reddy BV, Lerner EA: Nitric oxide synthase in toxic epidermal necrolysis and Stevens-Johnson syndrome. J Invest Dermatol 114:196-199, 2000
20. Marletta MA, Hurshman AR, Rusche KM: Catalysis by nitric oxide synthase. Curr Opin Chem Biol 2:656-663, 1998
21. Nicotera P, Orrenius S: The role of calcium in apoptosis. Cell Calcium 23:173-180, 1998
22. 2+ influx through voltage-dependent calcium channels. J Neurochem 76:341-350, 2001
23. Packer MA, Murphy MP: Peroxynitrite causes calcium efflux from mitochondria which is prevented by cyclosporin A. FEBS Lett 345:237-240, 1994
24. Rawlingson A, Greenacre SA, Brain SD: Generation of peroxynitrite in localised, moderate temperature burns. Burns 26:223-227, 2000
25. Romero-Graillet C, Aberdam E, Biagoli N, Massabni W, Ortonne JP, Ballotti R: Ultraviolet B radiation acts through the nitric oxide and cGMP signal transduction pathway to stimulate melanogenesis in human melanocytes. J Biol Chem 271:28052-28056, 1996
26. Ryle CM, Breitkreutz D, Stark HJ, Leigh IM, Steinert PM, Roop D, Fusenig NE: Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HaCaT and in ras-transfected tumorigenic clones. Differentiation 40:42-54, 1989
27. Stennicke HR, Salvesen GS: Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem 272:25719-25723, 1997
28. Szabó C: The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. Shock 6:79-88, 1996
29. Szabó É, Virág L, Bakondi E, et al: Peroxynitrite production, DNA breakage and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-reduced contact hypersensitivity. J Invest Dermatol 117:74-80, 2001
30. Tasker RC, Sahota SK, Cotter FE, Williams SR: Early postischemic dantrolene-induced amelioration of poly(ADP-ribose) polymerase-related bioenergetic failure in neonatal rat brain slices. J Cereb Blood Flow Metab 18:1346-1356, 1998
31. 2+ chelators reduce early excitotoxic and ischemic neuronal injury in vitro and in vivo. Neuron 11:221-235, 1993
32. Ueda N, Shah SV: Role of intracellular calcium in hydrogen peroxide-induced renal tubular cell injury. Am J Physiol 263 (2 Part 2):F214-F221, 1992
33. Vessey DA, Lee KH, Boyer TD: Differentiation-induced enhancement of the ability of cultured human keratinocytes to suppress oxidative stress. J Invest Dermatol 104:355-358, 1995
34. Virág L, Szabó C: The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54:375-429, 2002
35. Virág L, Scott GS, Cuzzocrea S, Marmer D, Salzman AL, Szabó C: Peroxynitrite-induced thymocyte apoptosis: The role of caspases and poly-(ADP-ribose) synthetase (PARS) activation. Immunology 94:345-355, 1998a
36. Virág L, Salzman A, Szabó C: Poly(ADP-ribose) synthetase activation mediates mitochondrial injury dunng oxidant-induced cell death. J Immunol 161:3753-3759, 1998b
37. Virág L, Scott GS, Antal-Szalmas P, O'Connor M, Ohshima H, Szabo C: Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity. Mol Pharmacol 56:824-833, 1999
38. Virág L, Szabó , Bakondi E, Bai P, Gergely P, Hunyadi J, Szabó C: The nitric oxide-peroxynitrite-poly(ADP-ribose) polymerase pathway in the skin. Exp Dermatol 11:189-202, 2002
39. Warren JB: Nitric oxide and human skin blood flow responses to acetylcholine and ultraviolet light. FASEB J 8:247-251, 1994
40. Weller R: Nitric oxide - a newly discovered chemical transmitter in human skin. Br J Dermatol 137:665-672, 1997
41. Weller R, Pattullo S, Smith L, Golden M, Ormerod A, Benjamin N: Nitric oxide is generated on the skin surface by reduction of sweat nitrate. J Invest Dermatol 107:327-331, 1996
42. Yamasaki K, Edington HD, McClosky C, et al: Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer. J Clin Invest 101:967-971, 1998
43. Ying W, Chen Y, Alano CC, Swanson RA: Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes. J Cereb Blood Flow Metab 22:774-779, 2002
44. Yuspa SH, Hennings H, Tucker RW, Jaken S, Kilkenny AE, Roop DR: Signal transduction for proliferation and differentiation in keratinocytes. Ann NY Acad Sci 548:191-196, 1988