Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP- ribose) polymerase and Ca2+ chelation: Involvement of a common mechanism

Biochemical Pharmacology

Volumn 57, Issue 1, 1999, Pages 19-26

  Karczewski, Jurgen M ^a   Peters, Janny G P ^a   Noordhoek, Jan ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

3 aminobenzamide; Calcium; DNA damage; Hydrogen peroxide; Menadione; Poly(ADP ribose) polymerase

Indexed keywords

2,3 DIMETHOXY 1,4 NAPHTHOQUINONE; ADENOSINE TRIPHOSPHATE; CALCIUM ION; HYDROGEN PEROXIDE; MENADIONE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ARTICLE; CANCER CELL CULTURE; CELL DEATH; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA DEGRADATION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; BENZAMIDES; CACO-2 CELLS; CALCIUM; CELL DEATH; CHELATING AGENTS; DNA DAMAGE; DNA, NEOPLASM; EGTAZIC ACID; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; KINETICS; NAD; NAPHTHOQUINONES; OXIDANTS; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; VITAMIN K;

EID: 0032897348     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00286-X     Document Type: Article

References (46)

1. Bast A., Goris R.J. Oxidative stress. Biochemistry and human disease. Pharm Weekbl Sci. 11:1989;199-206.
2. Iantomasi T., Marraccini P., Favilli F., Vincenzini M.T., Ferretti P., Tonelli F. Glutathione metabolism in Crohn's disease. Biochem Med Metabol Biol. 53:1994;87-91.
3. Babbs C.F. Oxygen radicals in ulcerative colitis. Free Radical Biol Med. 13:1992;169-181.
4. Nilsson U.A., Olsson L.I., Thor H., Moldeus P., Bylund-Fellenius A.C. Detection of oxygen radicals during reperfusion of intestinal cells in vitro. Free Radical Biol Med. 6:1989;251-259.
5. Osborne D.L., Aw T.Y., Cepinskas G., Kvietys P.R. Development of ischemia/reperfusion tolerance in the rat small intestine. An epithelium-independent event. J Clin Invest. 94:1994;1910-1918.
6. Thor H., Smith M.T., Hartzell P., Bellomo G., Jewell S.A., Orrenius S. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. J Biol Chem. 257:1982;12419-12425.
7. DiMonte D., Ross D., Bellomo G., Eklöw L., Orrenius S. Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch Biochem Biophys. 235:1984;334-342.
8. 2+ homeostasis. Arch Biochem Biophys. 235:1984;343-350.
9. Mirabelli F., Salis A., Perotti M., Taddei F., Bellomo G., Orrenius S. Alterations of surface morphology caused by the metabolism of menadione in mammalian cells are associated with the oxidation of critical sulfhydryl groups in the cytoskeletal proteins. Biochem Pharmacol. 37:1988;3423-3427.
10. Mirabelli F., Salis A., Marinoni V., Finardi G., Bellomo G., Thor H., Orrenius S. Menadione-induced bleb formation in hepatocytes is associated with the oxidation of thiol groups in actin. Arch Biochem Biophys. 264:1988;261-269.
11. 2+-ATPase activity by menadione metabolism and its restoration by thiols. FEBS Lett. 181:1985;149-153.
12. Cantoni O., Fiorani M., Cattabeni F., Bellomo G. DNA breakage caused by hydrogen peroxide produced by the metabolism of 2-methyl-1, 4-naphthoquinone (menadione) does not contribute to the toxicity of the cytotoxic action of the quinone. Biochem Pharmacol. 42:1991;S220-S222.
13. Fischer-Nielsen A., Corcoran G.B., Poulsen H.E., Kamendulis L.M., Loft S. Menadione-induced DNA fragmentation without 8-oxo-2′deoxyguanosine formation in isolated rat hepatocytes. Biochem Pharmacol. 49:1995;1469-1474.
14. Morrison H., Jernström B., Nordenskjöld H., Thor H., Orrenius S. Induction of DNA damage by menadione (2-methyl-1,4-naphthoquinone) in primary cultures of rat hepatocytes. Biochem Pharmacol. 33:1984;1763-1769.
15. Martins E.A., Meneghini R. DNA damage and lethal effects of hydrogen peroxide and menadione in Chinese hamster cells Distinct mechanisms are involved . Free Radical Biol Med. 8:1990;433-440.
16. Morgan W.A., Harley J.A., Cohen G.M. Quinone-induced DNA single strand breaks in rat hepatocytes and human chronic myelogenous leukaemic K562 cells. Biochem Pharmacol. 44:1992;215-221.
17. Lautier D., Lagueux J., Thibodeau J., Menard L., Poirier G.G. Molecular and biochemical features of poly(ADP-ribose) metabolism. Mol Cell Biochem. 122:1993;171-193.
18. Schraufstatter I.U., Hinshaw D.B., Hyslop P.A., Spragg R.A., Cochrane C.G. Glutathione cycle activity and pyridine nucleotide levels in oxidant-induced injury of cells. J Clin Invest. 76:1985;1131-1139.
19. Schraufstatter I.U., Hinshaw D.B., Hyslop P.A., Spragg R.A., Cochrane C.G. Oxidant injury of cells. J Clin Invest. 77:1986;1312-1320.
20. Schraufstatter I.U., Hyslop P.A., Hinshaw D.B., Spragg R.A., Sklar L.A., Cochrane C.G. Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose)polymerase. Proc Natl Acad Sci USA. 83:1986;4908-4912.
21. Realini C.A., Althaus F.R. Histone shuttling by poly(ADP-ribosylation). J Biol Chem. 267:1992;18858-18865.
22. Sims J.L., Berger S.J., Berger N.A. Poly(ADP-ribose)polymerase inhibitors preserve nicotinamide adenine dinucleotide and adenosine 5′-triphosphate pools in DNA-damaged cells Mechanism of stimulation of unscheduled DNA synthesis . Biochemistry. 22:1983;5188-5194.
23. Miesel R, Kröger H, Zuber M, Gratz R and Neth J, Elevated levels of oxygen- and nitrogen-centered radicals in patients with rheumatic diseases. Z Rheumatol53: 6-?, 1994.
24. Miesel R., Kurpisz M., Kröger H. Modulation of inflammatory arthritis by inhibition of poly (ADP-ribose) polymerase. Inflammation. 19:1995;379-387.
25. Pinto M., Robine-Leon S., Appay M.D., Kedinger M., Triadou N., Dussaulx E., Lacroix B., Simon-Assman P., Haffen K., Fogh J., Zweibaum A. Enterocyt-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture. Biol Cell. 47:1983;323-330.
26. Gant T.W., Ramakrishna Rao D.N., Mason R.P., Cohen G.M. Redox cycling and sulphydryl arylation Their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes . Chem-Biol Interact. 65:1988;157-173.
27. Borenfreund E., Puerner J.A. Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicol Lett. 24:1985;119-124.
28. Cotgreave I.A., Moldeus P. Methodologies for the application of monobromobimane to the simultaneous analysis of soluble and protein thiol component of biological systems. J Biochem Bioph Meth. 13:1986;231-249.
29. Birnboim H.C., Jevcak J.J. Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation. Cancer Res. 41:1981;1889-1892.
30. 2+ chelators prevent DNA damage and protect hepatoma 1C1C7 cells from quinone-induced cell killing. Free Radical Res. 8:1990;347-354.
31. De Murcia G., Menissier de Murcia J. Poly(ADP-ribose) polymerase A molecular nick-sensor . Trends Biochem Sci. 19:1994;172-176.
32. Patel T., Gores G.J., Kaufmann S.H. The role of proteases during apoptosis. FASEB J. 10:1996;587-597.
33. Nosseri C., Coppola S., Ghibelli L. Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis. Exp Cell Res. 212:1994;367-373.
34. Eguchi Y., Shimizu S., Tsujimoto Y. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. 57:1997;1835-1840.
35. Bellomo G., Mirabelli F., DiMonte D., Richelmi P., Thor H., Orrenius C., Orrenius S. Formation and reduction of glutathione-protein mixed disulfides during oxidative stress. A study with isolated hepatocytes and menadione (2-methyl-1,4-naphthoquinone). Biochem Pharmacol. 36:1987;1313-1320.
36. Redegeld F.A.M., Moison R.M.W., Barentsen H.M., Koster A.S., Noordhoek J. Interaction with cellular ATP generating pathways mediates menadione-induced cytotoxicity in isolated rat hepatocytes. Arch Biochem Biophys. 280:1990;130-136.
37. Stubberfield C.R., Cohen G.M. Interconversion of NAD(H) to NADP(H). A cellular response to quinone-induced oxidative stress in isolated hepatocytes. Biochem Pharmacol. 38:1989;2631-2637.
38. Banasik M., Komura H., Ueda K. Inhibition of poly(ADP-ribose) synthetase by fatty acids, vitamins and vitamin-like substances. FEBS Lett. 263:1990;222-224.
39. Marini M., Frabetti F., Brunelli M.A., Raggi M.A. Inhibition of poly (ADP-ribose) polymerization preserves the glutathione pool and reverses cytotoxicity in hydrogen peroxide-treated lymphocytes. Biochem Pharmacol. 46:1993;2139-2144.
40. Baker S., Baker R.D. Caco-2 cell metabolism of oxygen-derived radicals. Digest Dis Sci. 38:1993;2273-2280.
41. 2+ concentration and cytotoxicity in hepatocytes exposed to oxidative stress. Toxicology. 52:1988;55-63.
42. 2+ Physiological regulation and role in apoptosis . Mol Cell Biochem. 135:1994;89-98.
43. Arends M.J., Morris R.G., Wyllie A.H. Apoptosis, the role of endonucleases. Am J Pathol. 136:1990;593-608.
44. McConkey D.J., Hartzell P., Nicotera P., Wyllie A.H., Orrenius S. Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stress. Toxicol Lett. 42:1988;123-130.
45. Jones D.P., McConkey D.J., Nicotera P., Orrenius S. Calcium-activated DNA fragmentation in rat liver nuclei. J Biol Chem. 264:1989;6398-6403.
46. 2+-dependent endonuclease. Proc Natl Acad Sci USA. 72:1975;289-293.