-
1
-
-
0024581819
-
Phenotypic heterogeneity in familial Alzheimer's disease: A study of 24 kindreds
-
Bird T.D., Sumi S.M., Nemens E.J., Nochlin D., Schellenberg G., Lampe T.H., Sadovnick A., Chui H., Miner G.W., Tinklenberg J. Phenotypic heterogeneity in familial Alzheimer's disease: a study of 24 kindreds. Ann. Neurol. 25:1989;12-25.
-
(1989)
Ann. Neurol.
, vol.25
, pp. 12-25
-
-
Bird, T.D.1
Sumi, S.M.2
Nemens, E.J.3
Nochlin, D.4
Schellenberg, G.5
Lampe, T.H.6
Sadovnick, A.7
Chui, H.8
Miner, G.W.9
Tinklenberg, J.10
-
2
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt D.R., Ratovitski T., van Lare J., Lee M.K., Gonzales V., Jenkins N.A., Copeland N.G., Price D.L., Sisodia S.S. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron. 19:1997;939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
3
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
-
Citron M., Westaway D., Xia W., Carlson G., Diehl T., Levesque G., Johnson-Wood K., Lee M., Seubert P., Davis A., Kholodenko D., Motter R., Sherrington R., Perry B., Yao H., Strome R., Lieberburg I., Rommens J., Kim S., Schenk D., Fraser P., St. George-Hyslop P., Selkoe D.J. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice. Nat. Med. 3:1997;67-72.
-
(1997)
Nat. Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St. George-Hyslop, P.22
Selkoe, D.J.23
more..
-
4
-
-
0028861041
-
Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3
-
Cruts M., Backhovens H., Wang S.-Y., Gassen G.V., Theuns J., Jonghe C.D., Wehnert A., Voecht J.D., Winter G.D., Cras P., Bruyland M., Datson N., Weissenbach J., den Dunnen J.T., Martin J.-J., Hendriks L., Van Broeckhoven C. Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3. Hum. Mol. Genet. 4:1995;2363-2371.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 2363-2371
-
-
Cruts, M.1
Backhovens, H.2
Wang, S.-Y.3
Gassen, G.V.4
Theuns, J.5
Jonghe, C.D.6
Wehnert, A.7
Voecht, J.D.8
Winter, G.D.9
Cras, P.10
Bruyland, M.11
Datson, N.12
Weissenbach, J.13
Den Dunnen, J.T.14
Martin, J.-J.15
Hendriks, L.16
Van Broeckhoven, C.17
-
5
-
-
15444341611
-
Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins
-
De Strooper B., Beullens M., Contreras B., Levesque L., Craessaerts K., Cordell B., Moechars D., Bollen M., Fraser P., George-Hyslop P.S., Van Leuven F. Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins. J. Biol. Chem. 272(6):1997;3590-3598.
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.6
, pp. 3590-3598
-
-
De Strooper, B.1
Beullens, M.2
Contreras, B.3
Levesque, L.4
Craessaerts, K.5
Cordell, B.6
Moechars, D.7
Bollen, M.8
Fraser, P.9
George-Hyslop, P.S.10
Van Leuven, F.11
-
6
-
-
16044366039
-
Increased amyloid-β42 (43) in brains of mice expressing mutant presenilin 1
-
Duff K., Eckman C., Zehr C., Yu X., Prada C.-M., Perez-Tur J., Hutton M., Buee L., Harigaya Y., Yager D., Morgan D., Gordon M.N., Holcomb L., Refolo L., Zenk B., Hardy J., Younkin S. Increased amyloid-β42 (43) in brains of mice expressing mutant presenilin 1. Nature. 383:1996;710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
7
-
-
0021803192
-
Démence présénile d'alzheimer transmise dans une famille étendue
-
Foncin J.-F., Salmon D., Supino-Viterbo V., Feldman R.G., Macchi G., Mariotti P., Scoppetta C., Caruso G., Bruni A.C. Démence présénile d'alzheimer transmise dans une famille étendue. Rev. Neurol. (Paris). 141:1985;194-202.
-
(1985)
Rev. Neurol. (Paris)
, vol.141
, pp. 194-202
-
-
Foncin, J.-F.1
Salmon, D.2
Supino-Viterbo, V.3
Feldman, R.G.4
MacChi, G.5
Mariotti, P.6
Scoppetta, C.7
Caruso, G.8
Bruni, A.C.9
-
8
-
-
0029664434
-
A beta-peptide length and apolipoprotein E genotype in Alzheimer's disease
-
Gearing M., Mori H., Mirra S.S. A beta-peptide length and apolipoprotein E genotype in Alzheimer's disease. Ann. Neurol. 39:1996;395-399.
-
(1996)
Ann. Neurol.
, vol.39
, pp. 395-399
-
-
Gearing, M.1
Mori, H.2
Mirra, S.S.3
-
9
-
-
15144345926
-
A novel presenilin-1 mutation: Increased β-amyloid and neurofibrillary changes
-
Gomez-Isla T., Wasco W., Pettngell W.P., Gurubhagavatula S., Schmidt S.D., Jondro P.D., McNamara M., Rodes L.A., DiBlasi T., Growdon W.B., Seubert P., Schenk D., Frowdon J.H., Hyman B.T., Tanzi R.E. A novel presenilin-1 mutation: Increased β-amyloid and neurofibrillary changes. Ann. Neurol. 41:1997;809-813.
-
(1997)
Ann. Neurol.
, vol.41
, pp. 809-813
-
-
Gomez-Isla, T.1
Wasco, W.2
Pettngell, W.P.3
Gurubhagavatula, S.4
Schmidt, S.D.5
Jondro, P.D.6
McNamara, M.7
Rodes, L.A.8
Diblasi, T.9
Growdon, W.B.10
Seubert, P.11
Schenk, D.12
Frowdon, J.H.13
Hyman, B.T.14
Tanzi, R.E.15
-
10
-
-
0019378145
-
Familial Alzheimer's disease in two kindreds of the same geographic and ethnic origin
-
Goudsmit J., White B.J., Weitkamp L.R., Keats B.J.B., Morrow C.H., Gajdusek D.K. Familial Alzheimer's disease in two kindreds of the same geographic and ethnic origin. J. Neurol. Sci. 49:1981;78-89.
-
(1981)
J. Neurol. Sci.
, vol.49
, pp. 78-89
-
-
Goudsmit, J.1
White, B.J.2
Weitkamp, L.R.3
Keats, B.J.B.4
Morrow, C.H.5
Gajdusek, D.K.6
-
11
-
-
0028179341
-
Chemical characterization of Aβ 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease
-
Gowing E., Roher A.E., Woods A.S., Cotter R.J., Chaney M., Little S.P., Ball M.J. Chemical characterization of Aβ 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease. J. Biol. Chem. 269:1994;10987-10990.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10987-10990
-
-
Gowing, E.1
Roher, A.E.2
Woods, A.S.3
Cotter, R.J.4
Chaney, M.5
Little, S.P.6
Ball, M.J.7
-
12
-
-
0028915895
-
Amyloid β protein (Aβ) in Alzheimer's disease brain
-
Gravina S.A., Ho L., Eckman C.B., Long K.E., Otvos L. Jr., Younkin L.H., Suzuki N., Younkin S.G. Amyloid β protein (Aβ) in Alzheimer's disease brain. J. Biol. Chem. 270:1995;7013-7016.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7013-7016
-
-
Gravina, S.A.1
Ho, L.2
Eckman, C.B.3
Long, K.E.4
Otvos L., Jr.5
Younkin, L.H.6
Suzuki, N.7
Younkin, S.G.8
-
13
-
-
0026101636
-
Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease
-
Hilbich C., Kisters-Woike B., Reed J., Masters C.L., Beyreuther K. Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease. J. Mol. Biol. 218:1991;149-163.
-
(1991)
J. Mol. Biol.
, vol.218
, pp. 149-163
-
-
Hilbich, C.1
Kisters-Woike, B.2
Reed, J.3
Masters, C.L.4
Beyreuther, K.5
-
14
-
-
0028919919
-
Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down syndrome
-
Iwatsubo T., Mann D.M., Odaka A., Suzuki N., Ihara Y. Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down syndrome. Ann. Neurol. 37:1995;294-299.
-
(1995)
Ann. Neurol.
, vol.37
, pp. 294-299
-
-
Iwatsubo, T.1
Mann, D.M.2
Odaka, A.3
Suzuki, N.4
Ihara, Y.5
-
15
-
-
0027195933
-
Seeding 'one-dimensional crystallization' of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
-
Jarrett J.T., Lansbury P.T. Seeding 'one-dimensional crystallization' of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell. 73:1993;1055-1058.
-
(1993)
Cell
, vol.73
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury, P.T.2
-
16
-
-
0029995485
-
Accumulation of beta-amyloid fibrils in pancreas of transgenic mice
-
Kawarabayashi T., Shoji M., Sato M., Sasaki A., Ho L., Eckman C.B., Prada C., Younkin S.G., Kobayashi T., Tada N., Matsubara E., Iizuka T., Harihaya Y., Kasai K., Hirai S. Accumulation of beta-amyloid fibrils in pancreas of transgenic mice. Neurobiol. Aging. 17:1996;215-222.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 215-222
-
-
Kawarabayashi, T.1
Shoji, M.2
Sato, M.3
Sasaki, A.4
Ho, L.5
Eckman, C.B.6
Prada, C.7
Younkin, S.G.8
Kobayashi, T.9
Tada, N.10
Matsubara, E.11
Iizuka, T.12
Harihaya, Y.13
Kasai, K.14
Hirai, S.15
-
17
-
-
0010435675
-
-
PWS-Kent Publishing, Boston
-
D.G. Kleinbaum, L.L. Kupper, K.E. Muller, PWS-Kent Publishing, Boston, 1988, pp. 314-340.
-
(1988)
, pp. 314-340
-
-
Kleinbaum, D.G.1
Kupper, L.L.2
Muller, K.E.3
-
18
-
-
16044365171
-
The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology
-
Lemere C.A., Lopera F., Kosik K.S., Lendon C.L., Ossa J., Saido T.C., Yamaguchi H., Ruiz A., Martinez A., Madrigal L., Hincapie L., Arango J.C., Anthony D.C., Koo E.H., Goate A.M., Selkoe D.J. The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology. Nat. Med. 2:1996;1146-1150.
-
(1996)
Nat. Med.
, vol.2
, pp. 1146-1150
-
-
Lemere, C.A.1
Lopera, F.2
Kosik, K.S.3
Lendon, C.L.4
Ossa, J.5
Saido, T.C.6
Yamaguchi, H.7
Ruiz, A.8
Martinez, A.9
Madrigal, L.10
Hincapie, L.11
Arango, J.C.12
Anthony, D.C.13
Koo, E.H.14
Goate, A.M.15
Selkoe, D.J.16
-
19
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E., Wijsman E.M., Nemens E., Anderson L., Goddard K.A.B., Weber J.L., Bird T.D., Schellenberg G.D. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science. 269:1995;970-973.
-
(1995)
Science
, vol.269
, pp. 970-973
-
-
Levy-Lahad, E.1
Wijsman, E.M.2
Nemens, E.3
Anderson, L.4
Goddard, K.A.B.5
Weber, J.L.6
Bird, T.D.7
Schellenberg, G.D.8
-
20
-
-
0026688633
-
Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions
-
L'Hernault S.W.L., Arduengo P.M. Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions. J. Cell Biol. 119:1992;55-69.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 55-69
-
-
L'Hernault, S.W.L.1
Arduengo, P.M.2
-
21
-
-
9044239670
-
Familial and sporadic Alzheimer's disease: Neuropathology cannot exclude a final common pathway
-
Lippa C.F., Saunders A.M., Smith T.W., Swearer J.M., Drachman D.A., Ghetti B., Nee L., Pulaski-Salo D., Dickson D., Robitaille Y., Bergeron C., Crain B., Benson M.D., Farlow M., Hyman B.T., St. George-Hyslop P.H., Roses A.D., Pollen D.A. Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway. Neurology. 46:1996;406-412.
-
(1996)
Neurology
, vol.46
, pp. 406-412
-
-
Lippa, C.F.1
Saunders, A.M.2
Smith, T.W.3
Swearer, J.M.4
Drachman, D.A.5
Ghetti, B.6
Nee, L.7
Pulaski-Salo, D.8
Dickson, D.9
Robitaille, Y.10
Bergeron, C.11
Crain, B.12
Benson, M.D.13
Farlow, M.14
Hyman, B.T.15
St. George-Hyslop, P.H.16
Roses, A.D.17
Pollen, D.A.18
-
22
-
-
9444276544
-
Amyloid β protein (Aβ) deposition in chromosome 14-linked Alzheimer's disease: Predominance of Aβ 42(43)
-
Mann D.M.A., Iwatsubo T., Cairns N.J., lantos P.L., Nochlin D., Simi S.M., Bird M.D., Poorkaj P., Hardy J., Hutton M., Prihar G., Crook R., Rossor M.N., Haltia M. Amyloid β protein (Aβ) deposition in chromosome 14-linked Alzheimer's disease: predominance of Aβ 42(43). Ann. Neurol. 40:1996;149-156.
-
(1996)
Ann. Neurol.
, vol.40
, pp. 149-156
-
-
Mann, D.M.A.1
Iwatsubo, T.2
Cairns, N.J.3
Lantos, P.L.4
Nochlin, D.5
Simi, S.M.6
Bird, M.D.7
Poorkaj, P.8
Hardy, J.9
Hutton, M.10
Prihar, G.11
Crook, R.12
Rossor, M.N.13
Haltia, M.14
-
23
-
-
0021264594
-
Alzheimer's presenile dementia, senile dementia of Alzheimer type and down's syndrome in middle age form an age related continuum of pathological changes
-
Mann D.M.A., Yates P.O., Marcyniuk B. Alzheimer's presenile dementia, senile dementia of Alzheimer type and down's syndrome in middle age form an age related continuum of pathological changes. Neuropathol. Appl. Neurobiol. 10:1984;188-207.
-
(1984)
Neuropathol. Appl. Neurobiol.
, vol.10
, pp. 188-207
-
-
Mann, D.M.A.1
Yates, P.O.2
Marcyniuk, B.3
-
24
-
-
0025959458
-
Early-onset Alzheimer's disease in 2 large Belgian families
-
Martin J.J., Gheuens J., Bruyland M., Cras P., Vandenberghe A., Masters C.L., Beyreuther K., Dom R., Ceuterick C., Lubke U., Van Heuverswijin H., DeWinter G., Van Broeckhoven C. Early-onset Alzheimer's disease in 2 large Belgian families. Neurology. 41:1991;62-68.
-
(1991)
Neurology
, vol.41
, pp. 62-68
-
-
Martin, J.J.1
Gheuens, J.2
Bruyland, M.3
Cras, P.4
Vandenberghe, A.5
Masters, C.L.6
Beyreuther, K.7
Dom, R.8
Ceuterick, C.9
Lubke, U.10
Van Heuverswijin, H.11
Dewinter, G.12
Van Broeckhoven, C.13
-
25
-
-
0029416825
-
High levels of amyloid-beta protein from S182 (Glu246) familial Alzheimer's cells
-
Martins R.N., Turner B.A., Carroll R.T., Sweeney D., Kim K.S., Wisniewski H.M., Blass J.P., Gibson G.E., Gandy S. High levels of amyloid-beta protein from S182 (Glu246) familial Alzheimer's cells. NeuroReport. 7:1995;217-220.
-
(1995)
NeuroReport
, vol.7
, pp. 217-220
-
-
Martins, R.N.1
Turner, B.A.2
Carroll, R.T.3
Sweeney, D.4
Kim, K.S.5
Wisniewski, H.M.6
Blass, J.P.7
Gibson, G.E.8
Gandy, S.9
-
27
-
-
0026794746
-
Mass spectrometry of purified amyloid β protein in Alzheimer's disease
-
Mori H., Takio K., Ogawara M., Selkoe D.S. Mass spectrometry of purified amyloid β protein in Alzheimer's disease. J. Biol. Chem. 267:1992;17082-17086.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17082-17086
-
-
Mori, H.1
Takio, K.2
Ogawara, M.3
Selkoe, D.S.4
-
29
-
-
0020692622
-
A family with histologically confirmed Alzheimer's disease
-
Nee L., Polinski R.J., Eldridge R., Weingartner H., Smallberg S., Ebert M. A family with histologically confirmed Alzheimer's disease. Arch. Neurol. 40:1983;203-208.
-
(1983)
Arch. Neurol.
, vol.40
, pp. 203-208
-
-
Nee, L.1
Polinski, R.J.2
Eldridge, R.3
Weingartner, H.4
Smallberg, S.5
Ebert, M.6
-
30
-
-
0027447286
-
Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
-
Pike C.J., Burdick D., Walencewicz A.J., Glabe C.G., Cotman C.W. Neurodegeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. 13:1993;1676-1678.
-
(1993)
J. Neurosci.
, vol.13
, pp. 1676-1678
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
31
-
-
0028952749
-
Aggregation of secreted amyloid β-protein into sodium dodecyl sulfate-stable oligomers in cell culture
-
Podlisny M.B., Ostaszewski B.L., Squazzo S.L., Koo E.H., Rydell R.E., Teplow D.B., Selkoe D.J. Aggregation of secreted amyloid β-protein into sodium dodecyl sulfate-stable oligomers in cell culture. J. Biol. Chem. 270:1995;9564-9570.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9564-9570
-
-
Podlisny, M.B.1
Ostaszewski, B.L.2
Squazzo, S.L.3
Koo, E.H.4
Rydell, R.E.5
Teplow, D.B.6
Selkoe, D.J.7
-
32
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev E.I., Sherrington R., Rogaeva E.A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., Tsuda T., Mar L., Sorbi S., Nacmias B., Piacentini S., Amaducci L., Chumakov I., Cohen D., Lannfelt L., Fraser P.E., Rommens J.M., St. George-Hyslop P.H. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature. 376:1995;775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holman, K.9
Tsuda, T.10
Mar, L.11
Sorbi, S.12
Nacmias, B.13
Piacentini, S.14
Amaducci, L.15
Chumakov, I.16
Cohen, D.17
Lannfelt, L.18
Fraser, P.E.19
Rommens, J.M.20
St. George-Hyslop, P.H.21
more..
-
34
-
-
0027327267
-
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders A.M., Strittmatter W.J., Schmechel S., St. George-Hyslop P., Pericak-Vance M.A., Joo S.H., Rosi B.L., Gusella J.F., Crapper-McLachlan D.R., Growden J., Alberts M.J., Hulette C., Crain B., Goldgaber D., Roses A.D. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology. 43:1993;1467-1472.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, S.3
St. George-Hyslop, P.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-McLachlan, D.R.9
Growden, J.10
Alberts, M.J.11
Hulette, C.12
Crain, B.13
Goldgaber, D.14
Roses, A.D.15
-
35
-
-
16044373524
-
Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D., Eckman C., Jensen M., Song X., Citron M., Suzuki N., Bird T.D., Hardy J., Hutton M., Kukull W., Larson E., Levy-Lahad E., Viitanen M., Peskind E., Poorkaj P., Schellenberg G., Tanzi R., Wasco W., Lannfelt L., Selkoe D., Younkin S. Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2:1996;864-870.
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
36
-
-
0028267440
-
Normal and abnormal biology of the beta-amyloid precursor protein
-
Selkoe D.J. Normal and abnormal biology of the beta-amyloid precursor protein. Annu. Rev. Neurosci. 17:1994;489-517.
-
(1994)
Annu. Rev. Neurosci.
, vol.17
, pp. 489-517
-
-
Selkoe, D.J.1
-
37
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R., Rogaev E.I., Liang Y., Rogaeva E.A., Levesque G., Ikeda M., Chi H., Lin C., Li G., Holman K., Tsuda T., Mar L., Foncin J.F., Bruni A.C., Montesi M.P., Sorbi S., Rainero I., Pinessi L., Nee L., Chumakov I., Pollen D., Brookes A., Sanseau P., Polinski R.J., Wasco W., Da Silva H.A.R., Haines J.L., Pericak-Vance M.A., Tanzi R.E., Roses A.D., Fraser P.E., Rommens J.M., St. George-Hyslop P.H. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375:1995;754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainero, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.21
Brookes, A.22
Sanseau, P.23
Polinski, R.J.24
Wasco, W.25
Da Silva, H.A.R.26
Haines, J.L.27
Pericak-Vance, M.A.28
Tanzi, R.E.29
Roses, A.D.30
Fraser, P.E.31
Rommens, J.M.32
St. George-Hyslop, P.H.33
more..
-
38
-
-
0030775361
-
Amyloid β-protein (Aβ) 1-40 but not Aβ1-42 contributes to the experimental formation of Alzheimer disease amyloid fibrils in rat brain
-
Shin R.-W., Ogino K., Kondo A., Saido T.C., Trojanowski J.Q., Kitamoto T., Tateishi J. Amyloid β-protein (Aβ) 1-40 but not Aβ1-42 contributes to the experimental formation of Alzheimer disease amyloid fibrils in rat brain. J. Neurosci. 17:1997;8187-8193.
-
(1997)
J. Neurosci.
, vol.17
, pp. 8187-8193
-
-
Shin, R.-W.1
Ogino, K.2
Kondo, A.3
Saido, T.C.4
Trojanowski, J.Q.5
Kitamoto, T.6
Tateishi, J.7
-
39
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter W.J., Saunders A.M., Schmechel D., Pericak-Vance M., Enghild J., Salvesen G.S., Roses A.D. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 90:1993;1977-1981.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
40
-
-
0028322017
-
An increased percentage of long amyloid β protein secreted by familial amyloid β protein precursor (βAPP717) mutants
-
Suzuki N., Cheung T.T., Cai X.-D., Odaka A., Otvos L. Jr., Eckman C., Golde T.E., Younkin S.G. An increased percentage of long amyloid β protein secreted by familial amyloid β protein precursor (βAPP717) mutants. Science. 264:1994;1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.-D.3
Odaka, A.4
Otvos L., Jr.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
41
-
-
0028587336
-
APP717 missense mutation affects the ratio of amyloid beta protein species (A beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain
-
Tamaoka A., Odaka A., Ishibashi Y., Usami M., Sahara N., Suzuki N., Nukina N., Mizusawa H., Shoji S., Kanazawa I., Mori H. APP717 missense mutation affects the ratio of amyloid beta protein species (A beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain. J. Biol. Chem. 269:1994;32721-32724.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32721-32724
-
-
Tamaoka, A.1
Odaka, A.2
Ishibashi, Y.3
Usami, M.4
Sahara, N.5
Suzuki, N.6
Nukina, N.7
Mizusawa, H.8
Shoji, S.9
Kanazawa, I.10
Mori, H.11
-
42
-
-
0028922520
-
Amyloid β protein 1-42/43 (Aβ1-42/43) in cerebellar diffuse plaques: Enzyme-linked immunosorbent assay and immunocytochemical study
-
Tamaoka A., Sawamura N., Odaka A., Suzuki N., Mizusawa H., Shoji S., Mori H. Amyloid β protein 1-42/43 (Aβ1-42/43) in cerebellar diffuse plaques: enzyme-linked immunosorbent assay and immunocytochemical study. Brain Res. 679:1995;151-156.
-
(1995)
Brain Res.
, vol.679
, pp. 151-156
-
-
Tamaoka, A.1
Sawamura, N.2
Odaka, A.3
Suzuki, N.4
Mizusawa, H.5
Shoji, S.6
Mori, H.7
-
43
-
-
8044231311
-
The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum
-
Walter J., Capell A., Grunberg J., Pesold B., Schindzielorz A., Prior R., Podlisny M.B., Fraser P., St. George-Hyslop P., Selkoe D., Haass C. The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum. Mol. Med. 2:1996;673-691.
-
(1996)
Mol. Med.
, vol.2
, pp. 673-691
-
-
Walter, J.1
Capell, A.2
Grunberg, J.3
Pesold, B.4
Schindzielorz, A.5
Prior, R.6
Podlisny, M.B.7
Fraser, P.8
St. George-Hyslop, P.9
Selkoe, D.10
Haass, C.11
|