Mechanisms of VE-cadherin processing and degradation in microvascular endothelial cells

Journal of Biological Chemistry

Volumn 278, Issue 21, 2003, Pages 19199-19208

  Xiao, Kanyan ^a,b   Allison, David F ^a,b   Kottke, Margaret D ^a,b   Summers, Susan ^a,b   Sorescu, George P ^a,b   Faundez, Victor ^a   Kowalczyk, Andrew P ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; GROWTH KINETICS;

ENDOTHELIAL CELLS;

BIOCHEMISTRY;

BETA CATENIN; CADHERIN; CHLOROQUINE; INTERLEUKIN 2 RECEPTOR; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; CYSTEINE PROTEINASE; HYBRID PROTEIN; LEUKOCYTE ANTIGEN; MULTIENZYME COMPLEX; PROTEASOME; RECOMBINANT PROTEIN;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; DOWN REGULATION; ENDOSOME; ENDOTHELIUM CELL; GROWTH REGULATION; HUMAN; HUMAN CELL; INTERNALIZATION; MOLECULAR MECHANICS; MORPHOGENESIS; NEWBORN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; VASCULAR ENDOTHELIUM; ADENOVIRUS; ANIMAL; CELL CULTURE; CELL JUNCTION; CELL LINE; CELL STRAIN COS1; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GENE DELETION; GENE EXPRESSION; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; KIDNEY; LYSOSOME; MALE; METABOLISM; MICROCIRCULATION; MUTAGENESIS; SKIN; VASCULARIZATION; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; ANTIGENS, CD; BLOTTING, WESTERN; CADHERINS; CELL LINE; CELLS, CULTURED; CHLOROQUINE; COS CELLS; CYSTEINE ENDOPEPTIDASES; ENDOSOMES; ENDOTHELIUM, VASCULAR; FLUORESCENT ANTIBODY TECHNIQUE; GENE DELETION; GENE EXPRESSION; GENETIC VECTORS; HUMANS; INTERCELLULAR JUNCTIONS; KIDNEY; LYSOSOMES; MALE; MICROCIRCULATION; MULTIENZYME COMPLEXES; MUTAGENESIS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, INTERLEUKIN-2; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SKIN; TRANSFECTION;

EID: 0038820001     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211746200     Document Type: Article

References (50)

1. Stevens, T., Garcia, J. G., Shasby, D. M., Bhattacharya, J., and Malik, A. B. (2000) Am. J. Physiol. 279, L419-L422
2. Dejana, E., Spagnuolo, R., and Bazzoni, G. (2001) Thromb. Haemost. 86, 308-315
3. Bazzoni, G., and Dejana, E. (2001) Microcirculation 8, 143-152
4. Gottardi, C. J., and Gumbiner, B. M. (2001) Curr. Biol. 11, R792-R794
5. Breviario, F., Caveda, L., Corada, M., Martin-Padura, I., Navarro, P., Golay, J., Introna, M., Gulino, D., Lampugnani, M. G., and Dejana, E. (1995) Arterioscler. Thromb. Vasc. Biol. 15, 1229-1239
6. Anastasiadis, P. Z., Moon, S. Y., Thoreson, M. A., Mariner, D. J., Crawford, H. C., Zheng, Y., and Reynolds, A. B. (2000) Nat. Cell Biol. 2, 637-644
7. Thoreson, M. A., Anastasiadis, P. Z., Daniel, J. M., Ireton, R. C., Wheelock, M. J., Johnson, K. R., Hummingbird, D. K., and Reynolds, A. B. (2000) J. Cell Biol. 148, 189-202
8. Noren, N. K., Liu, B. P., Burridge, K., and Kreft, B. (2000) J. Cell Biol. 150, 567-580
9. Angst, B. D., Marcozzi, C., and Magee, A. I. (2001) J. Cell Sci. 114, 629-641
10. Aberle, H., Butz, S., Stappert, J., Weissig, H., Kemler, R., and Hoschuetzky, H. (1994) J. Cell Sci. 107, 3655-3663
11. Knudsen, K. A., and Wheelock, M. J. (1992) J. Cell Biol. 118, 671-679
12. Knudsen, K. A., Soler, A. P., Johnson, K. R., and Wheelock, M. J. (1995) J. Cell Biol. 130, 67-77
13. Jou, T.-S., Stewart, D. B., Stappert, J., Nelson, W. J., and Marrs, J. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5067-5071
14. Kowalczyk, A. P., Navarro, P., Dejana, E., Bornslaeger, E. A., Green, K. J., Kopp, D. S., and Borgwardt, J. E. (1998) J. Cell Sci. 111, 3045-3057
15. Schmelz, M., and Franke, W. W. (1993) Eur. J. Cell Biol. 61, 274-289
16. Schmelz, M., Moll, R., Kuhn, C., and Franke, W. W. (1994) Differentiation 57, 97-117
17. Valiron, O., Chevier, V., Usson, Y., Breviario, F., Job, D., and Dejana, E. (1996) J. Cell Sci. 109, 2141-2149
18. Christofori, G., and Semb, H. (1999) Trends Biochem. Sci. 24, 73-76
19. Miller, J. R., and McClay, D. R. (1997) Dev. Biol. 192, 323-339
20. Frid, M. G., Kale, V. A., and Stenmark, K. R. (2002) Circ. Res. 90, 1189-1196
21. Bobryshev, Y. V., Cherian, S. M., Inder, S. J., and Lord, R. S. (1999) Cardiovasc. Res. 43, 1003-1017
22. Amagai, M., Fujimori, T., Masunaga, T., Shimizu, H., Nishikawa, T., Shimizu, N., Takeichi, M., and Hashimoto, T. (1995) J. Invest. Dermatol. 104, 27-32
23. Fujimori, T., and Takeichi, M. (1993) Mol. Biol. Cell 4, 37-47
24. Kintner, C. (1992) Cell 69, 225-236
25. Zhu, A. J., and Watt, F. M. (1996) J. Cell Sci. 109, 3013-3023
26. Norvell, S. M., and Green, K. J. (1998) J. Cell Sci. 111, 1305-1318
27. Nieman, M. T., Kim, J. B., Johnson, K. R., and Wheelock, M. J. (1999) J. Cell Sci. 112, 1621-1632
28. Troxell, M. L., Chen, Y. T., Cobb, N., Nelson, W. J., and Marrs, J. A. (1999) Am. J. Physiol. 276, C404-C418
29. Venkiteswaran, K., Xiao, K., Summers, S., Calkins, C. C., Vincent, P. A., Pumiglia, K., and Kowalczyk, A. P. (2002) Am. J. Physiol. 283, C811-C821
30. Le, T. L., Joseph, S. R., Yap, A. S., and Stow, J. L. (2002) Am. J. Physiol. 283, C489-C499
31. Le, T. L., Yap, A. S., and Stow, J. L. (1999) J. Cell Biol. 146, 219-232
32. Navarro, P., Caveda, L, Breviario, F., Mandoteanu, I., Lampugnani, M. G., and Dejana, E. (1995) J. Biol. Chem. 52, 30965-30972
33. LaFlamme, S. E., Thomas, L. A., Yamada, S. S., and Yamada, K. M. (1994) J. Cell Biol. 126, 1287-1298
34. Pham, C. G., Harpf, A. E., Keller, R. S., Vu, H. T., Shai, S. Y., Loftus, J. C., and Ross, R. S. (2000) Am. J. Physiol. 279, H2916-H2926
35. He, T. C., Zhou, S., da Costa, L. T., Yu, J., Kinzler, K. W., and Vogelstein, B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 2509-2514
36. Benelli, R., and Albini, A. (1999) Int. J Biol. Markers 14, 243-246
37. Corada, M., Liao, F., Lindgren, M., Lampugnani, M. G., Breviario, F., Frank, R., Muller, W. A., Hicklin, D. J., Bohlen, P., and Dejana, E. (2001) Blood 97, 1679-1684
38. Hicke, L. (2001) Nat. Rev. Mol. Cell. Biol. 2, 195-201
39. Fujita, Y., Krause, G., Scheffner, M., Zechner, D., Leddy, H. E., Behrens, J., Sommer, T., and Birchmeier, W. (2002) Nat. Cell Biol. 4, 222-231
40. Chen, Y. T., Stewart, D. B., and Nelson, W. J. (1999) J. Cell Biol. 144, 687-699
41. Huber, A. H., Stewart, D. B., Laurents, D. V., Nelson, W. J., and Weis, W. I. (2001) J. Biol. Chem. 276, 12301-12309
42. Alexander, J. S., Jackson, S. A., Chaney, E., Kevil, C. G., and Haselton, F. R. (1998) Inflammation 22, 419-433
43. Kevil, C. G., Okayama, N., and Alexander, J. S. (2001) Am. J. Physiol. 281, C1940-C1947
44. Marambaud, P., Shioi, J., Serban, G., Georgakopoulos, A., Sarner, S., Nagy, V., Baki, L., Wen, P., Efthimiopoulos, S., Shao, Z., Wisniewski, T., and Robakis, N. K. (2002) EMBO J. 21, 1948-1956
45. Herren, B., Levkau, B., Raines, E. W., and Ross, R. (1998) Mol. Biol. Cell 9, 1589-1601
46. Steinhusen, U., Weiske, J., Badock, V., Tauber, R., Bommert, K., and Huber, O. (2001) J. Biol. Chem. 276, 4972-4980
47. Swaminathan, S., Amerik, A. Y., and Hochstrasser, M. (1999) Mol. Biol. Cell 10, 2583-2594
48. Strous, G. J., van Kerkhof, P., Govers, R., Ciechanover, A., and Schwartz, A. L. (1996) EMBO J. 15, 3806-3812
49. van Kerkhof, P., Govers, R., Alves dos Santos, C. M., and Strous, G. J. (2000) J. Biol. Chem. 275, 1575-1580
50. van Kerkhof, P., and Strous, G. J. (2001) Biochem. Soc. Trans. 29, 488-493