A new strategy for improved nicotine vaccines using conformationally constrained haptens

Journal of the American Chemical Society

Volumn 125, Issue 24, 2003, Pages 7164-7165

  Meijler, Michael M ^a   Matsushita, Masayuki ^a   Altobell III, Laurence J ^a   Wirsching, Peter ^a   Janda, Kim D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE; HAPTEN; NICOTINE; NICOTINE VACCINE; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANTIGENICITY; AQUEOUS SOLUTION; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG DESIGN; DRUG MANUFACTURE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; IMMUNE RESPONSE; LIGAND BINDING; PROTON TRANSPORT; STRUCTURE ANALYSIS;

ENZYME-LINKED IMMUNOSORBENT ASSAY; HAPTENS; HEMOCYANIN; IMMUNOCONJUGATES; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NICOTINE; PYRIDINES; VACCINES;

EID: 0038789010     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja034805t     Document Type: Article

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