Detection of resistance to clarithromycin in clinical isolates of Helicobacter pylori from children and adults;Deteccion de resistencia a claritromicina en aislamientos clínicos de Helicobacter pylori de niños y adultos

Revista Espanola de Quimioterapia

Volumn 16, Issue 1, 2003, Pages 53-57

  Vega, A E ^a,b   Alarcón, Teresa ^a   Domingo, D ^a   Martinez M J ^c   Lopez Brea M ^a  

^a HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^b UNIVERSIDAD NACIONAL DE SAN LUIS   (Argentina)

^c HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS   (Spain)

Author keywords

Clarithromycin; Helicobacter pylori; PCR RFLP; Resistance

Indexed keywords

CLARITHROMYCIN; ANTIINFECTIVE AGENT; BACTERIAL DNA; RNA 23S;

ADULT; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL INFECTION; BACTERIUM ISOLATION; CHILD; GENE MUTATION; GENETIC SUSCEPTIBILITY; HELICOBACTER PYLORI; HUMAN; MINIMUM INHIBITORY CONCENTRATION; POLYMERASE CHAIN REACTION; PREVALENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STRAIN DIFFERENCE; DRUG EFFECT; GENETICS; GENOTYPE; HELICOBACTER INFECTION; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MUTATION;

ADULT; ANTI-BACTERIAL AGENTS; CHILD; CLARITHROMYCIN; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RNA, RIBOSOMAL, 23S;

EID: 0038665304     PISSN: 02143429     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Blaser, M.J. Ecology of Helicobacter pylori in the human stomach. J Clin Invest 1997; 100: 759-762.
2. - Dunn, B.E., Cohen, H., Blaser, M.J. Helicobacter pylori. Clin Microbiol Rev 1997; 10: 720-741.
3. Van Door, L., Debets-Ossenkopp, Y., Marais, A. y cols. Rapid detection, by PCR and reverse hybridization, of mutations in the Helicobacter pylori 23S rRNA gene, associated with macrolide resistance. Antimicrob Agents Chemother 1999; 43: 1779-1782.
4. De Boer, W.A., Tytgat, G. The best therapy of Helicobacter pylori infection. Scand J Gastroenterol 1995; 30: 401-407.
5. Van der Hulst, R., Keller, J., Rauws, E., Tytgat, G. Treatment of Helicobacter pylori: Review of the world literature. Helicobacter 1996; 1: 6-19.
6. Hultén, K., Gibreel, A. Skold, O., Engstrand, L. Macrolide resistance in Helicobacter pylori: Mechanism and stability in strains from clarithromycin-treated patients. Antimicrob Agents Chemother 1997; 41: 2550-2553.
7. Occhialini, A., Urdaci, M., Doucet-Populaire, F., Bébear, C., Lamouliatte, H., Mégraud, F. Macrolide resistance in Helicobacter pylory: Rapid detection of point mutations and assays of macrolide binding to ribosomes. Antimicrob Agents Chemother 1997; 41: 2724-2728.
8. Versalovic, J., Shortridge, D., Kibbler, K. y cols. Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. Antimicrob Agents Chemother 1996; 40: 477-480.
9. Van Door, L., Glupczynski, Y., Kusters, J. y cols. Accurate prediction of macrolide resistance in Helicobacter pylori by a PCR line probe assay for detection of mutations in the 23S rRNA gene: Multicenter validation study. Antimicrob Agents Chemother 2001; 45: 1500-1504.
10. Mdgraud, F. Resistance of Helicobacter pylori to antibiotics. Aliment Pharmacol Ther 1997; 11 (Suppl. 1): 43-53.
11. Mdgraud, F., Lehn, N., Lind, T. y cols. Antimicrobial susceptibility testing of Helicobacter pylori in a large multicenter trial: The MACH 2 study. Antimicrob Agents Chemother 1999; 43: 2747-2752.
12. Van Zwet, A., De Boer, W., Schneeberger, P., Weel, J., Jansz A., Thijs, J. Prevalence of primary Helicobacter pylori resistance to metronidazole and clarithromycin in the Netherlands. Eur J Clin Microbiol Infect Dis 1996; 15: 861-864.
13. López-Brea, M., Martínez, M.J., Domingo, D., Alarcón, T. A 9 year study of clarithromycin and metronidazole resistance in Helicobacterpylori from Spanish children. J Antimicrob Chemother 2001; 48: 295-297.
14. Kato, S., Fujimura, S., Udagawa, H. y cols. Antibiotic resistance of Helicobacter pylori strains in Japanese children. J Clin Microbiol 2002; 40: 649-653.
15. Alarcón, T., Domingo, D., López-Brea, M. Antibiotic resistance problems with Helicobacter pylori. Int J Antimicrob Agents 1999; 12: 19-26.
16. Dore, M., Leandro, G., Realdi, G., Sepúlveda, A., Graham, D. Effect of pretreatment antibiotic resistance to metronidazole and clarithromycin on outcome of Helicobacter pylori therapy: A meta-analytical approach. Dig Dis Sci 2000; 45: 68-76.
17. Houben, M., Van der Beek, D., Hensen, E., Craen, A., Rauws, E., Tytgat, G. A systematic review of Helicobacter pylori eradication therapy. The impact of antimicrobial resistance on eradication rates. Aliment Pharmacol Ther 1999; 13: 1047-1055.
18. Glupczynski, Y., Burette, A. Drug therapy for Helicobacter pylori infection: Problems and pitfalls. Am J Gastroenterol 1990; 85: 1545-1551.
19. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. Tenth Informational Supplement (aerobic dilution). NCCLS document M100-S10 (M7). NCCLS, Wayne, Pa. 2000.
20. Midolo, P., Bell, J., Lambert, J., Turnidge, J., Grayson, M. Antimicrobial resistance testing of Helicobacter pylori: A comparison of E-test and disk diffusion methods. Pathology 1997; 29: 411-414,
21. Taylor, D., Ge, Z., Purych, D., Lo, T., Go, G. Cloning and sequence analysis of two copies of a 23S rRNA gene from Helicobacter pylori and association of clarithromycin resistance with 23S rRNA mutations. Antimicrob Agents Chemother 1997; 41: 2621-2628.
22. Alarcón, T., Vega, A.E., Domingo, D., Martínez, M.J., López-Brea, M. Clarithromycin resistance among Helicobacter pylori strains isolated from children: Prevalence and study of mechanism of resistance by PCR-Restriction Fragment Length Polymorphism analysis. J Clin Microbiol 2003; 41: 486-488.
23. Ge, W., Sayeedur Raham, M., Zafri Humayun, M., Taylor, D. Multiple sequence analysis demonstrates the competitive growth advantage of the A to G mutants of clarithromycin-resistant Helicobacter pylori. Antimicrob Agents Chemother 1999; 43: 683-685.
24. Ge, W., Taylor, D. Site-specific mutations in the 23S rRNA gene of Helicobacter pylori confer two types of resistance to macrolide-lincosamide-streptogramin B antibiotics. Antimicrob Agents Chemother 1998; 42: 1952-1958.
25. Alarcón, T., Domingo, D., Prieto, N., López-Brea, M. Clarithromycin resistance stability in Helicobacter pylori: Influence of the MIC and type of mutation in the 23S rRNA. J Antimicrob Chemother 2000; 46: 613-616.