Effect of pretreatment antibiotic resistance to metronidazole and clarithromycin on outcome of Helicobacter pylori therapy: A meta-analytical approach

Digestive Diseases and Sciences

Volumn 45, Issue 1, 2000, Pages 68-76

  Dore, Maria Pina ^a,b,c   Leandro, Gioacchino ^a,b,c   Realdi, Giuseppe ^a,b,c   Sepulveda, Antonia Rogado ^a,b,c   Graham, David Yates ^a,b,c  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SASSARI   (Italy)

^c NATIONAL INSTITUTE FOR DIGESTIVE DISEASES   (Italy)

Author keywords

Clarithromycin; Helicobacter pylori; Meta analysis; Metronidazole; Resistance; Therapy

Indexed keywords

CLARITHROMYCIN; METRONIDAZOLE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; TREATMENT OUTCOME;

ANTI-BACTERIAL AGENTS; CLARITHROMYCIN; DRUG RESISTANCE, MICROBIAL; HELICOBACTER PYLORI; HUMANS; METRONIDAZOLE; MICROBIAL SENSITIVITY TESTS;

EID: 0034003268     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005457226341     Document Type: Article

References (71)

1. 1. Anonymous: Gastroenterologist in Sydney-histology and Helicobacter. Lancet 336:779-780, 1990
2. 2. O'Riordan T, Mathai E, Tobin A, McKenna D, Keane C, Swecney E, O'Morain C: Adjuvant antibiotic therapy in duodenal ulcers treated with colloidal bismuth subcitrate. Gut 31:999-1002, 1990
3. 3. Megraud F: Resistance of Helicobacter pylori to antibiotics. Aliment Pharmacol Ther 11 (suppl 1):43-53, 1997
4. 4. Graham DY, Lew GM, Malaty HM, Evans DG, Evans DJ Jr, Klein PD, Alpert LC, Genta RM: Factors influencing the eradication of Helicobacter pylori with triple therapy. Gastroenterology 102:493-496, 1992
5. 5. Realdi G, Dore MP, Piana A, Atzei A, Carta M, Cugia L, Manca A, Are BM, Massarelli G, Mura I, Maida A, Graham DY: Pre-treatment antibiotic resistance in Helicobacter pylori infection: Results of three randomized, controlled studies. Helicobacter 4:106-112, 1999
6. 6. Glupczynski Y, Burette A: Drug therapy for Helicobacter pylori infection: Problems and pitfalls. Am J Gastroenterol 85:1545-1551, 1990
7. 7. Glupczynski Y: European Multicentre Study Group on antibiotic susceptibility of Helicobacter pylori. Results of a multicentre European survey in 1991 of metronidazole resistance in Helicobacter pylori. Eur J Clin Microbiol Infect Dis 11:777-781, 1992
8. 8. Haas CE, Nix DE, Shentag JJ: In vitro selection of resistant Helicobacter pylori. Antimicrob Agents Chemother 34:1637-1641, 1990
9. 9. Goodwill CS, Marshall BJ, Blincow ED, Wilson DH, Black-bourne S, Phillips M: Prevention of nitroimidazole resistance in Campylobacter pyloridis by coadministration of colloidal bismuth subcitrate: Clinical and in vitro studies. J Clin Pathol 41:207-210, 1988
10. 10. Graham DY, Dore MP: Variability in the outcome of treatment of Helicobacter pylori infection: A critical analysis. In Helicobacter pylori Basic Mechanisms to Clinical Cure 1998. RM Hunt and GNJ Tytgat (eds). Kluwer Academic Publishers, Dordrecht, The Netherlands, 1998, pp 426-441
11. 11. Graham DY: Antibiotic resistance in Helicobacter pylori: Implications for therapy. Gastroenterology 115:1272-1277, 1998
12. 12. Graham DY, de Boer WA, Tytgat GN: Choosing the best anti-Helicobacter pylori therapy: Effect of antimicrobial resistance. Am J Gastroenterol 91:1072-1076, 1996
13. 13. Galbraith RF: A note on graphical presentation of estimated odds ratios from several clinical trials. Stat Med 7:889-894, 1988
14. 14. META: The Right Handbook and Software to Understand and Practice Meta-Analysis. G. Leandro (eds). www.Media.it/ META (in progress)
15. 15. Xia H, Keane CT, Beattie S, O'Morain CA: Standardization of disk diffusion test and its clinical significance for susceptibility testing of metronidazole against Helicobacter pylori. Antimicrob Agents Chemother 38:2357-2361, 1994
16. 16. Rautelin H, Seppala K, Renkonen OV, Vainio U, Kosunen TU: Role of metronidazole resistance in therapy of Helicobacter pylori infections. Antimicrob Agents Chemother 36:163-166, 1992
17. 17. Lerang F, Moum B, Haug JB, Tolas P, Breder O, Aubert E, Hoie O, Soberg T, Flaaten B, Farup P, Berge T: Highly effective twice-daily triple therapies for Helicobacter pylori infection and peptic ulcer disease: Does in vitro metronidazole resistance have any clinical relevance? Am J Gastroenterol 92:248-253, 1997
18. 18. Fraser AG, Moore L, Ali MR, Chua LE, Hollis B, Little SV: An audit of low dose triple therapy for eradication of Helicobacter pylori: NZ Med J 109:290-292, 1996
19. 19. Ching CK, Leung KP, Yung RW, Lam SK, Wong BC, Lai KC: Prevalence of metronidazole resistant Helicobacter pylori strains among Chinese peptic ulcer disease patients and normal controls in Hong Kong. Gut 38:675-678, 1996
20. 20. Debets-Ossenkopp YJ. Sparrius M, Kusters JG, Kolkman JJ, Vandenbroucke-Grauls CM: Mechanism of clarithromycin resistance in clinical isolates of Helicobacter pylori. FEMS Microbiol Lett 142:37-42, 1996
21. 21. de Boer WA, van Etten RJ, Schade RW, Ouwehand ME, Schneeberger PM, van Unnik AJ, Tytgat GN: One-day intensified lansoprazole-quadruple therapy for cure of Helicobacter pylori infection. Aliment Pharmacol Ther 11:109-112, 1997
22. 22. Thijs JC, Van Zwet AA, Thijs WJ, Van der Wouden EJ, Kooy A: One-week triple therapy with omeprazole, amoxycillin and tinidazole for Helicobacter pylori infection: The significance of imidazole resistance. Aliment Pharmacol Ther 11:305-309, 1997
23. 23. Yousfi MM, el-Zimaity HM, al-Assi MT, Cole RA, Genta RM, Graham DY: Metronidazole, omeprazole and clarithromycin: an effective combination therapy for Helicobacter pylori infection. Aliment Pharmacol Ther 9:209-212, 1995
24. 24. Bell GD, Powell KU, Burridge SM, Bowden AN, Rameh B, Bolton G, Purser K, Harrison G, Brown C, Gant PW, Jones PH, Trowell JE: Helicobacter pylori eradication: Efficacy and side effect profile of a combination of omeprazole, amoxycillin and metronidazole compared with four alternative regimens. Q J Med 86:743-750, 1993
25. 25. Bell GD, Powell KU, Burridge SM, Bowden AF, Atoyebi W, Bolton GH, Jones PH, Brown C: Rapid eradication of Helicobacter pylori infection. Aliment Pharmacol Ther 9:41-46, 1995
26. 26. Seppala K, Farkkila M, Nuutinen H, Hakala K, Vaananen H, Rautelin H, Kosunen TU: Triple therapy of Helicobacter pylori infection in peptic ulcer. A 12-month follow-up study of 93 patients. Scand J Gastroenterol 27:976-976, 1992
27. 27. Thijs JC, Van Zwet AA, Oey HB: Efficacy and side effects of a triple drug regimen for the eradication of Helicobacter pylori. Scand J Gastroenterol 28:934-938, 1993
28. 28. Hosking SW, Ling TK, Chung SC, Yung MY, Cheng AF, Sung JJ, Li AK: Duodenal ulcer healing by eradication of Helicobacter pylori without anti-acid treatment: Randomized controlled trial. Lancet 343:508-510, 1994
29. 29. de Boer WA, Driessen WM, Jansz AR, Tytgat GN: Quadruple therapy compared with dual therapy for eradication of Helicobacter pylori in ulcer patients: Results of a randomized prospective single-center study. Eur J Gastroenterol Hepatol 7:1189-1194, 1995
30. 30. de Boer WA, Driessen W, Jansz A, Tytgat GN: Effect of acid suppression on efficacy of treatment for Helicobacter pylori infection. Lancet 345:817-820, 1995
31. 31. Noach LA, Langenberg WL, Bertola MA, Dankert J, Tytgat GN: Impact of metronidazole resistance on the eradication of Helicobacter pylori. Scand J Infect Dis 26:321-327, 1994
32. 32. Lyneh DA, Sobala GM, Gallacher B, Dixon MF, Axon AT: Effectiveness of a five times daily triple therapy regimen against Helicobacter pylori. J Antimicrob Chemother 33:877-879, 1994
33. 33. Labenz J, Peitz U, Tillenburg B, Becker T, Borsch G, Stolte M: Short-term triple therapy with pantoprazole, clarithromycin and metronidazole in eradication of Helicobacter pylori. Leber Magen Darm 25:122-127, 1995
34. 34. Logan RP, Gummett PA, Schaufelberger HD, Greaves RR, Mendelson GM, Walker MM, Thomas PH, Baron JH, Misiewicz JJ: Eradication of Helicobacter pylori with clarithromycin and omeprazole. Gut 35:323-326, 1994
35. 35. Wyeth JW, Pounder RE, Duggan AE, O'Morain CA, Schaufelberger HD, De Koster EH, Rauws EA, Bardhan KD, Gilvarry J, Buckley MJ, Gummett PA, Logan RP: The safety and efficacy of ranitidine bismuth citrate in combination with antibiotics for the eradication of Helicobacter pylori. Aliment Pharmacol Ther 10:623-630, 1996
36. 36. Hentschel E, Brandstatter G, Dragosics B, Hirschl AM, Nemec H, Schutze K, Taufer M, Wurzer H: Effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. N Engl J Med 328:308-312, 1993
37. 37. Moayyedi P, Sahay P, Tompkins DS, Axon AT: Efficacy and optimum dose of omeprazole in a new 1-week triple therapy regimen to eradicate Helicobacter pylori. Eur J Gastroenterol 7:835-840, 1995
38. 38. Thijs JC, van Zwet AA, Moolenaar W, Wolfhagen MJ, ten Bokkel Huinink J: Triple therapy vs. amoxicillin plus omeprazole for treatment of Helicobacter pylori infection: A multi-center, prospective, randomized, controlled study of efficacy and side effects. Am J Gastroenterol 91:93-97, 1996
39. 39. Bell GD, Powell K, Burridge SM, Pallecaros A, Jones PH, Gant PW, Harrison G, Trowell JE. Experience with "triple" anti-Helicobacter pylori eradication therapy: Side effects and the importance of testing the pre-treatment bacterial isolate muth subcitrate: Clinical and in vitro studies. J Clin Pathol 41:207-210, 1988
40. 40. Logan RP, Gummett PA, Misiewicz JJ, Karim QN, Walker MM, Baron JH: One week eradication regimen for Helicobacter pylori. Lancet 338:1249-1252, 1991
41. 41. Peterson WL, Graham DY, Marshall B, Blaser MJ, Genta RM, Klein PD, Stratton CW, Drnec J, Prokocimer P, Siepman N: Clarithromycin as monotherapy for eradication of Helicobacter pylori: A randomized, double-blind trial. Am J Gastroenterol 88:1860-1864, 1993
42. 42. de Boer WA, Driessen WM, Tytgat GN: Only four days of quadruple therapy can effectively cure Helicobacter pylori infection. Aliment Pharmacol Ther 9:633-638, 1995
43. 43. Gotoh A, Kawakami Y, Akahane T, Akamatsu T, Shimizu T, Kiyosawa K, Katsuyama T: Susceptibility of Helicobacter pylori isolates against agents commonly administered for eradication therapy and the efficacy of chemotherapy. Microbiol Immunol 41:7-12, 1997
44. 44. Borody TJ, Andrews P, Fracchia G, Brandl S, Shortis NP, Bae H: Omeprazole enhances efficacy of triple therapy in eradicating Helicobacter pylori. Gut 37:477-481, 1995
45. 45. de Boer WA, van Etten RJ, Schade RW, Ouwehand ME, Schneeberger PM, Tytgat GN: 4-Day lansoprazole quadruple therapy: A highly effective cure for Helicobacter pylori infection. Am J Gastroenterol 91:1778-1782, 1996
46. 46. Gisbert JP, Boixeda D, de Rafael L, Martin de Argila C, Bermejo F, Garcia Plaza A: The effect of "triple therapy" on the eradicating of H. pylori and the healing of a duodenal ulcer. The initial study and 6 months later. Rev Esp Enferm Dig 87:193-198, 1995
47. 47. Schütze K, Hentschel E, Hirschl AM: Clarithromycin or amoxycillin plus high-dose ranitidine in the treatment of Helicobacter pylori-positive functional dyspepsia. Eur J Gastroenterol Hepatol 8:41-46, 1996
48. 48. Glupezynski Y, Burette A, De Koster E, Nyst JF, Deltenre M, Cadranel S, Bourdeaux L, De Vos D: Metronidazole resistance in Helicobacter pylori. Lancet 335:976-977, 1990
49. 49. Bell GD, Powell KU: Helicobacter pylori reinfection after apparent eradication - the Ipswich experience. Scand J Gastroenterol 215(suppl 31):96-104, 1996
50. 50. DeCross AJ, Marshall BJ, McCallum RW, Hoffman SR, Barrett LJ, Guerrant RL: Metronidazole susceptibility testing for Helicobacter pylori: Comparison of disk, broth, and agar dilution methods and their clinical relevance. J Clin Microbiol 31:1971-1974, 1993
51. 51. Weil J, Bell GD, Powell K, Morden A, Harrison G, Gant PW, Jones PH, Trowell JE: Helicobacter pylori infection treated with a tripotassium dicitrato bismuthate and metronidazole combination. Aliment Pharmacol Ther 4:651-657, 1990
52. 52. Glupezynski Y, Burette A: Eradicating Helicobacter pylori. Lancet 339:54-55, 1992
53. 53. Gisbert JP, Boixeda D, de Rafael L, Redondo C, Martin de Argila C, Bermejo F: Which factors influence the success of the classical triple therapy in the eradication of Helicobacter pylori. Rev Esp Enferm Dig 88:317-322, 1996
54. 54. Midolo PD, Lambert JR, Turnidge J: Metronidazole resistance: A predictor of failure of Helicobacter pylori eradication by triple therapy. J Gastroenterol Hepatol 11:290-292, 1996
55. 55. Xia H, Daw MA, Sant S, Beattie S, Keane CT, O'Morain CA: Clinical efficacy of triple therapy in Helicobacter pylori-associated duodenal ulcer. Eur J Gastroenterol Hepatol 5:141-144, 1993
56. 56. Harris AW, Pryce DI, Gabe SM, Karim QN, Walker MM, Langworthy H, Baron JH, Misiewicz JJ: Lansoprazole, clarithromycin and metronidazole for seven days in Helicobacter pylori infection. Aliment Pharmacol Ther 10:1005-1008, 1996
57. 57. Powell KU, Bell GD, Boweden AF, Trowell JE, Jones PH: Helicobacter pylori eradication therapy: A comparison between either omeprazole or ranitidine in combination with amoxicillin plus metronidazole. Br J Clin Res 6:163-169, 1995
58. 58. Moayyedi P, Langworthy H, Shanahan K, Tompkins DS, Dixon MF, Chalmers DM, Axon AT: Comparison of one or two weeks of lansoprazole, amoxicillin, and clarithromycin in the treatment of Helicobacter pylori. Helicobacter 1:71-74, 1996
59. 59. Schwartz H, Krause R, Siepman N, Haber M, Weissfeld A, Kidd S, Rose P, Sahba B: Seven-day triple therapy with lansoprazole, clarithromycin, and metronidazole for the cure of Helicobacter pylori infection: A short report. Helicobacter 1:251-255, 1996
60. 60. Tompkins DS, Perkin J, Smith C: Failed treatment of Helicobacter pylori infection associated with resistance to clarithromycin. Helicobacter 2:185-187, 1997
61. 61. Tucci A, Corinaldesi R, Stanghellini V, Paparo GF, Gasperoni S, Biasco G, Varoli O, Ricci-Maccarini M, Barbara L: One-day therapy for treatment of Helicobacter pylori infection. Dig Dis Sci 38:1670-1673, 1993
62. 62. Thijs JC, Van Zwet AA, Moolenaar W, Oom JA, De Korte H, Runhaar: Short report: Clarithromycin, an alternative to metronidazole in the triple therapy of Helicobacter pylori infection. Aliment Pharmacol Ther 8:131-134, 1994
63. 63. Stupnicki T, Taufer M, Denk H, Ratschek M, Spath P, Graf K: Triple therapy with sucralfate, amoxycillin and metronidazole for healing duodenal ulcer and eradicating Helicobacter pylori infection. Aliment Pharmacol Ther 10:193-197, 1996
64. 64. Logan RP, Bardhan KD, Celestin LR, Theodossi A, Palmer KR, Reed PI, Baron JH, Misiewicz JJ: Eradication of Helicobacter pylori and prevention of recurrence of duodenal ulcer: A randomized, double-blind, multi-centre trial of omeprazole with or without clarithromycin. Aliment Pharmacol Ther 9:417-442, 1995
65. 65. van der Hulst RWM, Weel JF, van der Ende A, ten Kate FJ, Dankert J, Tytgat GN: Therapeutic options after failed Helicobacter pylori eradication therapy. Am J Gastroenterol 91:2333-2337, 1996
66. 66. Lerang F, Moum B, Ragnhildstveit E, Haug JB, Hauge T, Tolas P, Aubert E, Henriksen M, Efskind PS, Nicolaysen K, Soberg T, Odegaard A, Berge T: A comparison between omeprazole-based triple therapy and bismuth-based triple therapy for the treatment of Helicobacter pylori infection: A prospective randomized 1-yr follow-up study. Am J Gastroenterol 92:653-658, 1997
67. 67. Vautier G, Scott BB: A one-week quadruple eradication regimen for Helicobacter pylori in routine clinical practice. Aliment Pharmacol Ther 11:107-108, 1997
68. 68. Breuer T, Kim JG, Gurer IE, Graham DP, Osato M, Genta RM, Graham DY: Successful low-dose amoxycillin, metronidazole and omeprazole combination therapy in a population with a high frequency of metronidazole-resistant Helicobacter pylori. Aliment Pharmacol Ther 11:523-527, 1997
69. 69. Witteman EM, Hopman WP, Becx MC, De Koning RW, Tytgat GN, Janssen AJ, Jansen JB: Short report: smoking habits and the acquisition of metronidazole resistance in patients with Helicobacter pylori-related gastritis. Aliment Pharmacol Ther 7:683-687, 1993
70. 70. Versalovic J, Osato MS, Spakovsky K, Dore MP, Reddy R, Stone GG, Shortridge D, Flamm RK, Tanaka SK, Graham DY: Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance. J Antimicrob Chemother 40:283-286, 1997
71. 71. Stone GG, Shortridge D, Flamm RK, Versalovic J, Beyer J, Idler K, Zulawinski L, Tanaka SK: Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori. Helicobacter 1:227-228, 1996