메뉴 건너뛰기




Volumn 71, Issue 4, 1998, Pages 491-501

Antiproliferative effect of elevated glucose in human microvascular endothelial cells

Author keywords

Diabetic microangiopathy; Endothelium; HMEC 1

Indexed keywords

CALPHOSTIN C; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP DERIVATIVE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOSE; MANNITOL; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TRANSCRIPTION FACTOR AP 1;

EID: 0032534593     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19981215)71:4<491::AID-JCB4>3.0.CO;2-P     Document Type: Article
Times cited : (58)

References (43)
  • 1
    • 0025369136 scopus 로고
    • High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells
    • Ayo SH, Radnik RA, Garoni JA, Glass WF, Kreisberg JI (1990): High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am J Pathol 136:1339-1348.
    • (1990) Am J Pathol , vol.136 , pp. 1339-1348
    • Ayo, S.H.1    Radnik, R.A.2    Garoni, J.A.3    Glass, W.F.4    Kreisberg, J.I.5
  • 4
    • 0026317124 scopus 로고
    • Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters and cAMP
    • Cagliero E, Roth T, Roy S, Maiello M, Lorenzi M (1991): Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters and cAMP. J Biol Chem 266:14244-14250.
    • (1991) J Biol Chem , vol.266 , pp. 14244-14250
    • Cagliero, E.1    Roth, T.2    Roy, S.3    Maiello, M.4    Lorenzi, M.5
  • 5
    • 0024563795 scopus 로고
    • Protein kinase C is activated in glomeruli from streptozotocin diabetic rats
    • Craven PA, DeRubertis FR (1989): Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. J Clin Invest 83:1667-1675.
    • (1989) J Clin Invest , vol.83 , pp. 1667-1675
    • Craven, P.A.1    DeRubertis, F.R.2
  • 6
    • 0027054448 scopus 로고
    • Decreased cultured endothelial cell proliferation in high glucose medium is reversed by antioxidants: New insights on the pathophysiological mechanisms of diabetic vascular complications
    • Curcio F, Ceriello A (1992): Decreased cultured endothelial cell proliferation in high glucose medium is reversed by antioxidants: New insights on the pathophysiological mechanisms of diabetic vascular complications. In Vitro Cell Dev Biol 28A:787-790.
    • (1992) In Vitro Cell Dev Biol , vol.28 A , pp. 787-790
    • Curcio, F.1    Ceriello, A.2
  • 7
    • 0024343439 scopus 로고
    • Pancreatic islet transplantation ameliorates the effect of diabetes on retinal capillary endothelial cell kinetics
    • Cuthbertson RA, Mandel TE (1989): Pancreatic islet transplantation ameliorates the effect of diabetes on retinal capillary endothelial cell kinetics. Curr Eye Res 8:681-686.
    • (1989) Curr Eye Res , vol.8 , pp. 681-686
    • Cuthbertson, R.A.1    Mandel, T.E.2
  • 8
    • 0019466496 scopus 로고
    • Human dermal microvascular endothelial cells in vitro: Effect of cyclic AMP on cellular morphology and proliferation rate
    • Davison PM, Karasek MA (1981): Human dermal microvascular endothelial cells in vitro: Effect of cyclic AMP on cellular morphology and proliferation rate. J Cell Physiol 106:253-258.
    • (1981) J Cell Physiol , vol.106 , pp. 253-258
    • Davison, P.M.1    Karasek, M.A.2
  • 9
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG (1983): Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 10
    • 0029616040 scopus 로고
    • Cyclic strain causes heterogeneous induction of transcription factors, AP-1, CRE binding protein and NF-kB in endothelial cells: Species and vascular bed diversity
    • Du W, Mills I, Sumpio BE (1995): Cyclic strain causes heterogeneous induction of transcription factors, AP-1, CRE binding protein and NF-kB in endothelial cells: Species and vascular bed diversity. J Biomechanics 28: 1485-1491.
    • (1995) J Biomechanics , vol.28 , pp. 1485-1491
    • Du, W.1    Mills, I.2    Sumpio, B.E.3
  • 11
    • 0025848066 scopus 로고
    • Effects of glucose on migration, proliferation and tube formation by vascular endothelial cells
    • Hayashi JN, Ito H, Kanayasu T, Asuwa N, Morita I, Ishii T, Murota S (1991): Effects of glucose on migration, proliferation and tube formation by vascular endothelial cells. Virchows Arch 60:245-252.
    • (1991) Virchows Arch , vol.60 , pp. 245-252
    • Hayashi, J.N.1    Ito, H.2    Kanayasu, T.3    Asuwa, N.4    Morita, I.5    Ishii, T.6    Murota, S.7
  • 12
    • 0028897113 scopus 로고
    • Transcriptional regulation by extracellular signals: Mechanisms and specificity
    • Hill CS, Treisman R (1995): Transcriptional regulation by extracellular signals: Mechanisms and specificity. Cell 80:199-211.
    • (1995) Cell , vol.80 , pp. 199-211
    • Hill, C.S.1    Treisman, R.2
  • 13
    • 0026756232 scopus 로고
    • Intracellular cyclic AMP levels in endothelial cells subjected to cyclic strain in vitro
    • Iba T, Mills I, Sumpio BE (1992): Intracellular cyclic AMP levels in endothelial cells subjected to cyclic strain in vitro. J Surg Res 52:625-630.
    • (1992) J Surg Res , vol.52 , pp. 625-630
    • Iba, T.1    Mills, I.2    Sumpio, B.E.3
  • 14
    • 0026489335 scopus 로고
    • Preferential elevation of protein kinase C isoform βII and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation
    • Inoguchi T, Battan R, Handler E, Sportsman JR, Heath W, King GL (1992): Preferential elevation of protein kinase C isoform βII and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation. Proc Natl Acad Sci 89:11059-11063.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 11059-11063
    • Inoguchi, T.1    Battan, R.2    Handler, E.3    Sportsman, J.R.4    Heath, W.5    King, G.L.6
  • 16
    • 0029756590 scopus 로고    scopus 로고
    • The pathobiology of diabetes mellitus: Implications for surgeons
    • Kamal K, Powell RJ, Sumpio BE (1996): The pathobiology of diabetes mellitus: Implications for surgeons. J Am Coll Surg 183:271-288.
    • (1996) J Am Coll Surg , vol.183 , pp. 271-288
    • Kamal, K.1    Powell, R.J.2    Sumpio, B.E.3
  • 17
    • 0028321899 scopus 로고
    • Cellular and molecular abnormalities in the vascular endothelium of diabetes mellitus
    • King GL, Shiba T, Oliver J, Inoguchi T, Bursell S-E (1994): Cellular and molecular abnormalities in the vascular endothelium of diabetes mellitus. Annu Rev Med 45:179-188.
    • (1994) Annu Rev Med , vol.45 , pp. 179-188
    • King, G.L.1    Shiba, T.2    Oliver, J.3    Inoguchi, T.4    Bursell, S.-E.5
  • 18
    • 0024550448 scopus 로고
    • Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C
    • Kobayashi E, Nakano H, Morimoto M, Tamaoki T (1989): Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem Biophys Res Comm 159:548-553.
    • (1989) Biochem Biophys Res Comm , vol.159 , pp. 548-553
    • Kobayashi, E.1    Nakano, H.2    Morimoto, M.3    Tamaoki, T.4
  • 19
  • 20
    • 0028278181 scopus 로고
    • Signal transduction and gene regulation: The nuclear response to cAMP
    • Lalli E, Sassone-Corsi P (1994): Signal transduction and gene regulation: The nuclear response to cAMP. J Biol Chem 269:17359-17362.
    • (1994) J Biol Chem , vol.269 , pp. 17359-17362
    • Lalli, E.1    Sassone-Corsi, P.2
  • 21
    • 0000358508 scopus 로고
    • Activation of protein kinase C by elevation of glucose concentration: Proposal for a mechanism in the development of diabetic vascular complications
    • Lee T-S, Saltsman KA, Ohashi H, King GL (1989): Activation of protein kinase C by elevation of glucose concentration: Proposal for a mechanism in the development of diabetic vascular complications. Proc Natl Acad Sci USA 86:5141-5145.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5141-5145
    • Lee, T.-S.1    Saltsman, K.A.2    Ohashi, H.3    King, G.L.4
  • 22
    • 0021861537 scopus 로고
    • Glucose toxicity for human endothelial cells in culture. Delayed replication, disturbed cell cycle, and accelerated death
    • Lorenzi M, Cagliero E, Toledo S (1985): Glucose toxicity for human endothelial cells in culture. Delayed replication, disturbed cell cycle, and accelerated death. Diabetes 34: 621-627.
    • (1985) Diabetes , vol.34 , pp. 621-627
    • Lorenzi, M.1    Cagliero, E.2    Toledo, S.3
  • 23
    • 0022572994 scopus 로고
    • High glucose induces DNA damage in cultured human endothelial cells
    • Lorenzi M, Montisano DF, Toledo S, Barrieux A (1986): High glucose induces DNA damage in cultured human endothelial cells. J Clin Invest 77:322-325.
    • (1986) J Clin Invest , vol.77 , pp. 322-325
    • Lorenzi, M.1    Montisano, D.F.2    Toledo, S.3    Barrieux, A.4
  • 24
    • 0023628856 scopus 로고
    • High glucose prolongs cell-cycle traversal of cultured human endothelial cells
    • Lorenzi M, Nordberg JA, Toledo S (1987): High glucose prolongs cell-cycle traversal of cultured human endothelial cells. Diabetes 36:1261-1267.
    • (1987) Diabetes , vol.36 , pp. 1261-1267
    • Lorenzi, M.1    Nordberg, J.A.2    Toledo, S.3
  • 25
    • 0019394886 scopus 로고
    • 3H] thymidine techniques to measure cell proliferation
    • 3H] thymidine techniques to measure cell proliferation. Cell Tissue Kinet 14:111-120.
    • (1981) Cell Tissue Kinet , vol.14 , pp. 111-120
    • Maurer, H.R.1
  • 27
    • 0027253061 scopus 로고
    • Long-term complications of diabetes mellitus
    • Nathan DM (1993): Long-term complications of diabetes mellitus. N Engl J Med 328:1676-1685.
    • (1993) N Engl J Med , vol.328 , pp. 1676-1685
    • Nathan, D.M.1
  • 28
    • 0020693285 scopus 로고
    • Streptozotocin-induced diabetes produces alterations in adenylate cyclase in rat cerebrum, cerebral microvessels and retina
    • Palmer GC, Wilson GL, Chronister RB (1983): Streptozotocin-induced diabetes produces alterations in adenylate cyclase in rat cerebrum, cerebral microvessels and retina. Life Sci 32:365-374.
    • (1983) Life Sci , vol.32 , pp. 365-374
    • Palmer, G.C.1    Wilson, G.L.2    Chronister, R.B.3
  • 29
    • 0027771457 scopus 로고
    • Use of a human microvascular endothelial cell line as a model system to evaluate cholesterol uptake
    • Pruckler JM, Lawley TJ, Ades EW (1993): Use of a human microvascular endothelial cell line as a model system to evaluate cholesterol uptake. Pathobiology 61:283-287.
    • (1993) Pathobiology , vol.61 , pp. 283-287
    • Pruckler, J.M.1    Lawley, T.J.2    Ades, E.W.3
  • 30
    • 0021050701 scopus 로고
    • Inhibition of glycogenolysis in isolated rat hepatocytes by the Rp diasteriomer of adenosine 3′,5′-phosphorothioate
    • Rothermel JD, Stec WJ, Baraniak J, Jastorff B, Botelho LH (1983): Inhibition of glycogenolysis in isolated rat hepatocytes by the Rp diasteriomer of adenosine 3′,5′-phosphorothioate. J Biol Chem 258:12125-12128.
    • (1983) J Biol Chem , vol.258 , pp. 12125-12128
    • Rothermel, J.D.1    Stec, W.J.2    Baraniak, J.3    Jastorff, B.4    Botelho, L.H.5
  • 31
    • 0025067393 scopus 로고
    • Overexpression of fibronectin induced by diabetes or high glucose: Phenomenon with a memory
    • Roy S, Sala R, Cagliero E, Lorenzi M (1990): Overexpression of fibronectin induced by diabetes or high glucose: Phenomenon with a memory. Proc Natl Acad Sci USA 87:404-408.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 404-408
    • Roy, S.1    Sala, R.2    Cagliero, E.3    Lorenzi, M.4
  • 32
    • 0028913179 scopus 로고
    • Expression of growth-related protooncogenes during diabetic renal hypertrophy
    • Shankland SJ, Scholey JW (1995): Expression of growth-related protooncogenes during diabetic renal hypertrophy. Kidney Int 47:782-788.
    • (1995) Kidney Int , vol.47 , pp. 782-788
    • Shankland, S.J.1    Scholey, J.W.2
  • 33
    • 0021807568 scopus 로고
    • A morphologic and autoradiographic study of cell death and regeneration in the retinal microvasculature of normal and diabetic rats
    • Sharma NK, Gardiner TA, Archer DB (1985): A morphologic and autoradiographic study of cell death and regeneration in the retinal microvasculature of normal and diabetic rats. Am J Opthalmol 100:51-60.
    • (1985) Am J Opthalmol , vol.100 , pp. 51-60
    • Sharma, N.K.1    Gardiner, T.A.2    Archer, D.B.3
  • 34
    • 0027454103 scopus 로고
    • Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation
    • Shiba T, Inoguchi T, Sportsman JR, Heath WF, Bursell S, King GL (1993): Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation. Am J Physiol 265:E783-E793.
    • (1993) Am J Physiol , vol.265
    • Shiba, T.1    Inoguchi, T.2    Sportsman, J.R.3    Heath, W.F.4    Bursell, S.5    King, G.L.6
  • 35
    • 0029948733 scopus 로고    scopus 로고
    • Diabetic complications. The importance of glucose control
    • Skyler JS (1996): Diabetic complications. The importance of glucose control. Endocr Metab Clin N Amer 25:243-254.
    • (1996) Endocr Metab Clin N Amer , vol.25 , pp. 243-254
    • Skyler, J.S.1
  • 36
    • 0025646738 scopus 로고
    • Activation of cyclic AMP phosphodiesterase by phorbol and protein kinase C pathway: Differences in normal and diabetic tissue
    • Solomon SS, Chiang TM, Palazzolo MR (1990): Activation of cyclic AMP phosphodiesterase by phorbol and protein kinase C pathway: Differences in normal and diabetic tissue. Endocrine Res 16:391-402.
    • (1990) Endocrine Res , vol.16 , pp. 391-402
    • Solomon, S.S.1    Chiang, T.M.2    Palazzolo, M.R.3
  • 37
    • 0019978477 scopus 로고
    • Glucose inhibits replication of cultured human endothelial cells
    • Stout RW (1982): Glucose inhibits replication of cultured human endothelial cells. Diabetologia 23:436-439.
    • (1982) Diabetologia , vol.23 , pp. 436-439
    • Stout, R.W.1
  • 38
    • 0025832494 scopus 로고
    • Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C
    • Tesfamariam B, Brown ML, Cohen RA (1991): Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C. J Clin Invest 87:1643-1648.
    • (1991) J Clin Invest , vol.87 , pp. 1643-1648
    • Tesfamariam, B.1    Brown, M.L.2    Cohen, R.A.3
  • 39
    • 0026596233 scopus 로고
    • Diabetes alters the cyclic AMP response of isolated renal glomeruli
    • Thomas JH, Murray DC, Sharp PA (1992): Diabetes alters the cyclic AMP response of isolated renal glomeruli. Biochem Soc Trans 20:132S.
    • (1992) Biochem Soc Trans , vol.20
    • Thomas, J.H.1    Murray, D.C.2    Sharp, P.A.3
  • 40
    • 0025122079 scopus 로고
    • Cyclic adenosine monophosphate levels and the function of skin microvascular endothelial cells
    • Tuder RM, Karasek MA, Bensch KG (1990): Cyclic adenosine monophosphate levels and the function of skin microvascular endothelial cells. J Cell Physiol 142:272-283.
    • (1990) J Cell Physiol , vol.142 , pp. 272-283
    • Tuder, R.M.1    Karasek, M.A.2    Bensch, K.G.3
  • 41
    • 0021895108 scopus 로고
    • 3H] thymidine into myocardial capillary cells in streptozotocin-diabetic rats
    • 3H] thymidine into myocardial capillary cells in streptozotocin-diabetic rats. Exp Mol Pathol 43:135-141.
    • (1985) Exp Mol Pathol , vol.43 , pp. 135-141
    • Wickline, K.M.1    Fischer, V.W.2
  • 42
    • 0026035977 scopus 로고
    • Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels
    • Wolf BA, Williamson JR, Easom RA, Chang K, Sherman WR, Turk J (1991): Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels. J Clin Invest 87:31-38.
    • (1991) J Clin Invest , vol.87 , pp. 31-38
    • Wolf, B.A.1    Williamson, J.R.2    Easom, R.A.3    Chang, K.4    Sherman, W.R.5    Turk, J.6
  • 43
    • 0028322344 scopus 로고
    • Characterization of expression and modulation of cell adhesion molecules on an immortalized human dermal microvascular endothelial cell line (HMEC-1)
    • Xu Y, Swerlick RA, Sepp N, Bosse D, Ades EW, Lawley TJ (1994): Characterization of expression and modulation of cell adhesion molecules on an immortalized human dermal microvascular endothelial cell line (HMEC-1). J. Inv Dermatol 102:833-837.
    • (1994) J. Inv Dermatol , vol.102 , pp. 833-837
    • Xu, Y.1    Swerlick, R.A.2    Sepp, N.3    Bosse, D.4    Ades, E.W.5    Lawley, T.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.