The effects of Pluronic® block copolymers and Cremophor® EL on intestinal lipoprotein processing and the potential link with P-glycoprotein in Caco-2 cells

Pharmaceutical Research

Volumn 20, Issue 7, 2003, Pages 1085-1092

  Seeballuck, Fergal ^a   Ashford, Marianne B ^b   O'Driscoll, Caitriona M ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Caco 2; Cremophor EL; Lipophilic drug delivery; Lipoproteins; P glycoprotein; Pluronic block copolymers

Indexed keywords

COPOLYMER; CREMOPHOR; GLYCOPROTEIN P; LIPOPROTEIN; POLOXAMER; TRIACYLGLYCEROL; DRUG DERIVATIVE; GLYCEROL; POLYMER;

ARTICLE; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EXPOSURE; HUMAN; HUMAN CELL; INTESTINE; LIPOGENESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; CELL SURVIVAL; DOSE RESPONSE; DRUG COMBINATION; INTESTINE MUCOSA; METABOLISM; PHYSIOLOGY; SECRETION;

CACO-2 CELLS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; GLYCEROL; HUMANS; INTESTINAL MUCOSA; LIPOPROTEINS; P-GLYCOPROTEIN; POLOXAMER; POLYMERS;

EID: 0038537242     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024422625596     Document Type: Article

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