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Volumn 13, Issue 4, 2003, Pages 189-198

Pharmacogenetics of hepatocellular transporters

Author keywords

Cholestasis; Hepatocellular transporters; Pharmacogenetics

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; CARRIER PROTEIN; DRUG METABOLITE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; MULTIDRUG RESISTANCE PROTEIN 6; XENOBIOTIC AGENT;

EID: 0038523918     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200304000-00003     Document Type: Short Survey
Times cited : (40)

References (54)
  • 1
    • 0029893370 scopus 로고    scopus 로고
    • Sinusoidal (basolateral) bile salt uptake systems of hepatocytes
    • Hagenbuch B, Meier PJ. Sinusoidal (basolateral) bile salt uptake systems of hepatocytes. Semin Liver Dis 1996; 16:129-136.
    • (1996) Semin Liver Dis , vol.16 , pp. 129-136
    • Hagenbuch, B.1    Meier, P.J.2
  • 2
    • 0037427972 scopus 로고    scopus 로고
    • The superfamily of organic anion transporting polypeptides
    • Hagenbuch B, Meier PJ. The superfamily of organic anion transporting polypeptides. Biochim Biophys Acta 2003; 1609:1-18.
    • (2003) Biochim Biophys Acta , vol.1609 , pp. 1-18
    • Hagenbuch, B.1    Meier, P.J.2
  • 3
    • 0033921479 scopus 로고    scopus 로고
    • Structure of renal organic anion and cation transporters
    • Burckhardt G, Wolff NA. Structure of renal organic anion and cation transporters. Am J Physiol Renal Physiol 2000; 278:F853-F866.
    • (2000) Am J Physiol Renal Physiol , vol.278
    • Burckhardt, G.1    Wolff, N.A.2
  • 4
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian abc transporters in health and disease
    • Borst P, Elferink RO. Mammalian abc transporters in health and disease. Annu Rev Biochem 2002; 71:537-592.
    • (2002) Annu Rev Biochem , vol.71 , pp. 537-592
    • Borst, P.1    Elferink, R.O.2
  • 6
    • 0035045719 scopus 로고    scopus 로고
    • The wide spectrum of multidrug resistance 3 deficiency: From neonatal cholestasis to cirrhosis of adulthood
    • Jacquemin E, De Vree JM, Cresteil D, Sokal EM, Sturm E, Dumont M, et al. The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood. Gastroenterology 2001; 120:1448-1458.
    • (2001) Gastroenterology , vol.120 , pp. 1448-1458
    • Jacquemin, E.1    De Vree, J.M.2    Cresteil, D.3    Sokal, E.M.4    Sturm, E.5    Dumont, M.6
  • 7
    • 0033745088 scopus 로고    scopus 로고
    • Hepatic secretion of conjugated drugs and endogenous substances
    • Keppler D, Konig J. Hepatic secretion of conjugated drugs and endogenous substances. Semin Liver Dis 2000; 20:265-272.
    • (2000) Semin Liver Dis , vol.20 , pp. 265-272
    • Keppler, D.1    Konig, J.2
  • 8
    • 0036070539 scopus 로고    scopus 로고
    • Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug disposition
    • Gerk PM, Vore M. Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug disposition. J Pharmacol Exp Ther 2002; 302:407-415.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 407-415
    • Gerk, P.M.1    Vore, M.2
  • 9
    • 0036733732 scopus 로고    scopus 로고
    • Biliary cholesterol secretion by the twinned sterol half-transporters ABCG5 and ABCG8
    • Wittenburg H, Carey MC. Biliary cholesterol secretion by the twinned sterol half-transporters ABCG5 and ABCG8. J Clin Invest 2002; 110:605-609.
    • (2002) J Clin Invest , vol.110 , pp. 605-609
    • Wittenburg, H.1    Carey, M.C.2
  • 10
    • 0035200027 scopus 로고    scopus 로고
    • FIC1 disease: A spectrum of intrahepatic cholestatic disorders
    • van Mil SW, Klomp LW, Bull LN, Houwen RH. FIC1 disease: a spectrum of intrahepatic cholestatic disorders. Semin Liver Dis 2001; 21:535-544.
    • (2001) Semin Liver Dis , vol.21 , pp. 535-544
    • Van Mil, S.W.1    Klomp, L.W.2    Bull, L.N.3    Houwen, R.H.4
  • 12
    • 0036161690 scopus 로고    scopus 로고
    • FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low gamma-glutamyltranspeptidase levels
    • Chen HL, Chang PS, Hsu HC, Ni YH, Hsu HY, Lee JH, et al. FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low gamma-glutamyltranspeptidase levels. J Pediatr 2002; 140:119-124.
    • (2002) J Pediatr , vol.140 , pp. 119-124
    • Chen, H.L.1    Chang, P.S.2    Hsu, H.C.3    Ni, Y.H.4    Hsu, H.Y.5    Lee, J.H.6
  • 14
    • 17344366172 scopus 로고    scopus 로고
    • A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis
    • Strautnieks SS, Bull LN, Knisely AS, Kocoshis SA, Dahl N, Arnell H, et al. A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nature Genet 1998; 20:233-238.
    • (1998) Nature Genet , vol.20 , pp. 233-238
    • Strautnieks, S.S.1    Bull, L.N.2    Knisely, A.S.3    Kocoshis, S.A.4    Dahl, N.5    Arnell, H.6
  • 15
    • 0032711405 scopus 로고    scopus 로고
    • Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis
    • Jansen PL, Strautnieks SS, Jacquemin E, Hadchouel M, Sokal EM, Hooiveld GJ, et al. Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis. Gastroenterology 1999; 117:1370-1379.
    • (1999) Gastroenterology , vol.117 , pp. 1370-1379
    • Jansen, P.L.1    Strautnieks, S.S.2    Jacquemin, E.3    Hadchouel, M.4    Sokal, E.M.5    Hooiveld, G.J.6
  • 16
    • 0036790453 scopus 로고    scopus 로고
    • The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II
    • Wang L, Soroka CJ, Boyer JL. The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II. J Clin Invest 2002; 110:965-972.
    • (2002) J Clin Invest , vol.110 , pp. 965-972
    • Wang, L.1    Soroka, C.J.2    Boyer, J.L.3
  • 17
    • 0035205166 scopus 로고    scopus 로고
    • Role of multidrug resistance 3 deficiency in pediatric and adult liver disease: One gene for three diseases
    • Jacquemin E. Role of multidrug resistance 3 deficiency in pediatric and adult liver disease: one gene for three diseases. Semin Liver Dis 2001; 21:551-562.
    • (2001) Semin Liver Dis , vol.21 , pp. 551-562
    • Jacquemin, E.1
  • 18
    • 0035053975 scopus 로고    scopus 로고
    • MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis
    • Rosmorduc O, Hermelin B, Poupon R. MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis. Gastroenterology 2001; 120:1459-1467.
    • (2001) Gastroenterology , vol.120 , pp. 1459-1467
    • Rosmorduc, O.1    Hermelin, B.2    Poupon, R.3
  • 19
    • 0036830243 scopus 로고    scopus 로고
    • Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome
    • Hashimoto K, Uchiumi T, Konno T, Ebihara T, Nakamura T, Wada M, et al. Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome. Hepatology 2002; 36:1236-1245.
    • (2002) Hepatology , vol.36 , pp. 1236-1245
    • Hashimoto, K.1    Uchiumi, T.2    Konno, T.3    Ebihara, T.4    Nakamura, T.5    Wada, M.6
  • 20
    • 0033652766 scopus 로고    scopus 로고
    • Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome
    • Keitel V, Kartenbeck J, Nies AT, Spring H, Brom M, Keppler D. Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome. Hepatology 2000; 32:1317-1328.
    • (2000) Hepatology , vol.32 , pp. 1317-1328
    • Keitel, V.1    Kartenbeck, J.2    Nies, A.T.3    Spring, H.4    Brom, M.5    Keppler, D.6
  • 21
    • 0035813178 scopus 로고    scopus 로고
    • Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome
    • Mor-Cohen R, Zivelin A, Rosenberg N, Shani M, Muallem S, Seligsohn U. Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome. J Biol Chem 2001; 276:36923-36930.
    • (2001) J Biol Chem , vol.276 , pp. 36923-36930
    • Mor-Cohen, R.1    Zivelin, A.2    Rosenberg, N.3    Shani, M.4    Muallem, S.5    Seligsohn, U.6
  • 22
    • 0032926354 scopus 로고    scopus 로고
    • Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane
    • Konig J, Rost D, Cui Y, Keppler D. Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology 1999; 29:1156-1163.
    • (1999) Hepatology , vol.29 , pp. 1156-1163
    • Konig, J.1    Rost, D.2    Cui, Y.3    Keppler, D.4
  • 23
    • 0026583036 scopus 로고
    • Hepatobiliary complications of oral contraceptives
    • Lindberg MC. Hepatobiliary complications of oral contraceptives. J Gen Intern Med 1992; 7:199-209.
    • (1992) J Gen Intern Med , vol.7 , pp. 199-209
    • Lindberg, M.C.1
  • 25
    • 17644443114 scopus 로고    scopus 로고
    • Heterezygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: Evidence for a defect in protein trafficking
    • Dixon PH, Weerasekera N, Linton KJ, Donaldson O, Chambers J, Egginton E, et al. Heterezygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Hum Mol Genet 2000; 9:1209-1217.
    • (2000) Hum Mol Genet , vol.9 , pp. 1209-1217
    • Dixon, P.H.1    Weerasekera, N.2    Linton, K.J.3    Donaldson, O.4    Chambers, J.5    Egginton, E.6
  • 27
    • 0033023251 scopus 로고    scopus 로고
    • Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy
    • Jacquemin E, Cresteil D, Manouvrier S, Boute O, Hadchouel M. Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy. Lancet 1999; 353:210-211.
    • (1999) Lancet , vol.353 , pp. 210-211
    • Jacquemin, E.1    Cresteil, D.2    Manouvrier, S.3    Boute, O.4    Hadchouel, M.5
  • 28
    • 0035458853 scopus 로고    scopus 로고
    • Dietary cholesterol absorption; more than just bile
    • Lu K, Lee MH, Patel SB. Dietary cholesterol absorption; more than just bile. Trends Endocrinol Metab 2001; 12:314-320.
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 314-320
    • Lu, K.1    Lee, M.H.2    Patel, S.B.3
  • 30
    • 0035929574 scopus 로고    scopus 로고
    • Polymorphisms in OATP-C: Identification of multiple allelic variants associated with altered transport activity among European- and African-Americans
    • Tirona RG, Leake BF, Merino G, Kim RB. Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. J Biol Chem 2001; 276:35669-35675.
    • (2001) J Biol Chem , vol.276 , pp. 35669-35675
    • Tirona, R.G.1    Leake, B.F.2    Merino, G.3    Kim, R.B.4
  • 31
    • 18644368162 scopus 로고    scopus 로고
    • A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter
    • Michalski C, Cui Y, Nies AT, Nuessler AK, Neuhaus P, Zanger UM, et al. A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter. J Biol Chem 2002; 277:43058-43063.
    • (2002) J Biol Chem , vol.277 , pp. 43058-43063
    • Michalski, C.1    Cui, Y.2    Nies, A.T.3    Nuessler, A.K.4    Neuhaus, P.5    Zanger, U.M.6
  • 32
    • 0037131893 scopus 로고    scopus 로고
    • The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans
    • Fromm MF. The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans. Adv Drug Deliv Rev 2002; 54:1295-1310.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1295-1310
    • Fromm, M.F.1
  • 33
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in-vivo
    • Hoffmeyer S, Burk O, von Richter O, Arnold HP, Breckmoller J, Johne A, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in-vivo. Proc Natl Acad Sci USA 2000; 97:3473-3478.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    Von Richter, O.3    Arnold, H.P.4    Breckmoller, J.5    Johne, A.6
  • 34
    • 3042772026 scopus 로고    scopus 로고
    • Identification of functionally variant MDR1 alleles among European Americans and African Americans
    • Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI, et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70:189-199.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 189-199
    • Kim, R.B.1    Leake, B.F.2    Choo, E.F.3    Dresser, G.K.4    Kubba, S.V.5    Schwarz, U.I.6
  • 38
    • 0036667956 scopus 로고    scopus 로고
    • Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
    • Tang K, Ngoi SM, Gwee PC, Chua JM, Lee EJ, Chong SS, Lee CG. Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations. Pharmacogenetics 2002; 12:437-450.
    • (2002) Pharmacogenetics , vol.12 , pp. 437-450
    • Tang, K.1    Ngoi, S.M.2    Gwee, P.C.3    Chua, J.M.4    Lee, E.J.5    Chong, S.S.6    Lee, C.G.7
  • 39
    • 0034382936 scopus 로고    scopus 로고
    • Molecular mechanisms in bile formation
    • Meier PJ, Stieger B. Molecular mechanisms in bile formation. News Physiol Sci 2000; 15:89-93.
    • (2000) News Physiol Sci , vol.15 , pp. 89-93
    • Meier, P.J.1    Stieger, B.2
  • 40
    • 0036022838 scopus 로고    scopus 로고
    • Contribution of mrp2 in alterations of canalicular bile formation by the endothelin antagonist bosentan
    • Fouassier L, Kinnman N, Lefevre G, Lasnier E, Rey C, Poupon R, et al. Contribution of mrp2 in alterations of canalicular bile formation by the endothelin antagonist bosentan. J Hepatol 2002; 37:184-191.
    • (2002) J Hepatol , vol.37 , pp. 184-191
    • Fouassier, L.1    Kinnman, N.2    Lefevre, G.3    Lasnier, E.4    Rey, C.5    Poupon, R.6
  • 41
    • 0033361943 scopus 로고    scopus 로고
    • Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome
    • Toh S, Wada M, Uchiumi T, Inokuchi A, Makino Y, Horie Y, et al. Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome. Am J Hum Genet 1999; 64:739-746.
    • (1999) Am J Hum Genet , vol.64 , pp. 739-746
    • Toh, S.1    Wada, M.2    Uchiumi, T.3    Inokuchi, A.4    Makino, Y.5    Horie, Y.6
  • 42
    • 6844250107 scopus 로고    scopus 로고
    • Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome
    • Wada M, Toh S, Taniguchi K, Nakamura T, Uchiumi T, Kohno K, et al. Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome. Hum Mol Genet 1998; 7:203-207.
    • (1998) Hum Mol Genet , vol.7 , pp. 203-207
    • Wada, M.1    Toh, S.2    Taniguchi, K.3    Nakamura, T.4    Uchiumi, T.5    Kohno, K.6
  • 43
    • 0032545447 scopus 로고    scopus 로고
    • A splice mutation in the human canalicular multispecific organic anion transporter gene causes Dubin-Johnson syndrome
    • Kajihara S, Hisatomi A, Mizuta T, Hara T, Ozaki I, Wada I, Yamamoto K. A splice mutation in the human canalicular multispecific organic anion transporter gene causes Dubin-Johnson syndrome. Biochem Biophys Res Commun 1998; 253:454-457.
    • (1998) Biochem Biophys Res Commun , vol.253 , pp. 454-457
    • Kajihara, S.1    Hisatomi, A.2    Mizuta, T.3    Hara, T.4    Ozaki, I.5    Wada, I.6    Yamamoto, K.7
  • 44
    • 0032842748 scopus 로고    scopus 로고
    • Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome
    • Tsujii H, Konig J, Rost D, Stockel B, Leuschner U, Keppler D. Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome. Gastroenterology 1999; 117:653-660.
    • (1999) Gastroenterology , vol.117 , pp. 653-660
    • Tsujii, H.1    Konig, J.2    Rost, D.3    Stockel, B.4    Leuschner, U.5    Keppler, D.6
  • 48
    • 0034989076 scopus 로고    scopus 로고
    • Progressive familial intrahepatic cholestasis with high gamma- glutamyltranspeptidase levels in Taiwanese infants: Role of MDR3 gene defect?
    • Chen HL, Chang PS, Hsu HC, Lee JH, Ni YH, Hsu HY, et al. Progressive familial intrahepatic cholestasis with high gamma- glutamyltranspeptidase levels in Taiwanese infants: role of MDR3 gene defect? Pediatr Res 2001; 50:50-55.
    • (2001) Pediatr Res , vol.50 , pp. 50-55
    • Chen, H.L.1    Chang, P.S.2    Hsu, H.C.3    Lee, J.H.4    Ni, Y.H.5    Hsu, H.Y.6
  • 49
    • 0040368659 scopus 로고    scopus 로고
    • Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1
    • Abe T, Kakyo M, Tokui T, Nakagomi R, Nishio T, Nakai D, et al. Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J Biol Chem 1999; 274:17159-17163.
    • (1999) J Biol Chem , vol.274 , pp. 17159-17163
    • Abe, T.1    Kakyo, M.2    Tokui, T.3    Nakagomi, R.4    Nishio, T.5    Nakai, D.6
  • 50
    • 0033601257 scopus 로고    scopus 로고
    • A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
    • Hsiang B, Zhu Y, Wang Z, Wu Y, Sasseville V, Yang WP, Kirchgessner TG. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J Biol Chem 1999; 274:37161-37168.
    • (1999) J Biol Chem , vol.274 , pp. 37161-37168
    • Hsiang, B.1    Zhu, Y.2    Wang, Z.3    Wu, Y.4    Sasseville, V.5    Yang, W.P.6    Kirchgessner, T.G.7
  • 51
    • 0034997034 scopus 로고    scopus 로고
    • Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
    • Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, et al. Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J Pharmacol Exp Ther 2001; 297:1137-1143.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 1137-1143
    • Tanabe, M.1    Ieiri, I.2    Nagata, N.3    Inoue, K.4    Ito, S.5    Kanamori, Y.6
  • 52
    • 0037223561 scopus 로고    scopus 로고
    • Association between the 03435T MDR1 gene polymorphism and susceptibility for ulcerative colitis
    • Schwab M, Schaeffeler E, Marx C, Fromm MF, Kaskas B, Metzler J, et al. Association between the 03435T MDR1 gene polymorphism and susceptibility for ulcerative colitis. Gastroenterology 2003; 124:26-33.
    • (2003) Gastroenterology , vol.124 , pp. 26-33
    • Schwab, M.1    Schaeffeler, E.2    Marx, C.3    Fromm, M.F.4    Kaskas, B.5    Metzler, J.6
  • 53
    • 0037022006 scopus 로고    scopus 로고
    • Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study
    • Fellay J, Marzolini C, Meaden ER, Back DJ, Buclin T, Chave JP, et al. Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet 2002; 359:30-36.
    • (2002) Lancet , vol.359 , pp. 30-36
    • Fellay, J.1    Marzolini, C.2    Meaden, E.R.3    Back, D.J.4    Buclin, T.5    Chave, J.P.6


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