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Volumn 77, Issue 5, 2003, Pages 1269-1277

Determinants of hyperhomocysteinemia in patients with chronic liver disease and after orthotopic liver transplantation

Author keywords

Folic acid; Hepatitis; Homocysteine; Liver cirrhosis; Liver transplantation; Methionine load; Vitamin B 12; Vitamin B 6

Indexed keywords

AMINO ACID; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; CORTICOSTEROID; CREATININE; CYANOCOBALAMIN; CYCLOSPORIN; DIURETIC AGENT; FOLIC ACID; FOLSAURE HEVERT; HOMOCYSTEINE; METHIONINE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PYRIDOXINE; TSUKUBAENOLIDE; VITAMIN B GROUP;

EID: 0038474027     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/77.5.1269     Document Type: Article
Times cited : (45)

References (44)
  • 1
    • 0019414138 scopus 로고
    • Evidence for impairment of transsulfuration pathway in cirrhosis
    • Horowitz JH, Rypins EP, Henderson JM, et al. Evidence for impairment of transsulfuration pathway in cirrhosis. Gastroenterology 1981;81:668-75.
    • (1981) Gastroenterology , vol.81 , pp. 668-675
    • Horowitz, J.H.1    Rypins, E.P.2    Henderson, J.M.3
  • 2
    • 0026719322 scopus 로고
    • Defective methionine metabolism in cirrhosis: Relation to severity of liver disease
    • Marchisini G, Buglianesi E, Fabri A, Marchi E, Zoli M, Pisi E. Defective methionine metabolism in cirrhosis: relation to severity of liver disease. Hepatology 1992;16:149-55.
    • (1992) Hepatology , vol.16 , pp. 149-155
    • Marchisini, G.1    Buglianesi, E.2    Fabri, A.3    Marchi, E.4    Zoli, M.5    Pisi, E.6
  • 3
    • 0034772896 scopus 로고    scopus 로고
    • Basal and post-methionine serum homocysteine and lipoprotein abnormalities in patients with chronic liver disease
    • Ben-Ari Z, Tur-Kaspa R, Baruch Y, et al. Basal and post-methionine serum homocysteine and lipoprotein abnormalities in patients with chronic liver disease. J Invest Med 2001;49:325-9.
    • (2001) J Invest Med , vol.49 , pp. 325-329
    • Ben-Ari, Z.1    Tur-Kaspa, R.2    Baruch, Y.3
  • 4
    • 15644384507 scopus 로고    scopus 로고
    • Alcoholic cirrhosis and cobalamin metabolism
    • Lambert D, Benhayoun S, Adjalla C, et al. Alcoholic cirrhosis and cobalamin metabolism. Digestion 1997;58:64-71.
    • (1997) Digestion , vol.58 , pp. 64-71
    • Lambert, D.1    Benhayoun, S.2    Adjalla, C.3
  • 5
    • 0035117611 scopus 로고    scopus 로고
    • Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use
    • Koehler KM, Baumgartner RN, Garry PJ Allen, RH, Stabler SP, Rimm EB. Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use. Am J Clin Nutr 2001;73:628-37.
    • (2001) Am J Clin Nutr , vol.73 , pp. 628-637
    • Koehler, K.M.1    Baumgartner, R.N.2    Garry, P.J.3    Allen, R.H.4    Stabler, S.P.5    Rimm, E.B.6
  • 8
    • 0033821506 scopus 로고    scopus 로고
    • Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at level of gamma-cystathionase?
    • Look MP, Riezler R, Reichel C, et al. Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at level of gamma-cystathionase? Scand J Gastroenterol 2000;35:866-72.
    • (2000) Scand J Gastroenterol , vol.35 , pp. 866-872
    • Look, M.P.1    Riezler, R.2    Reichel, C.3
  • 10
    • 0035725225 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in liver cirrhosis: Mechanisms and role in vascular and hepatic fibrosis
    • Garcia-Tevijano ER, Berasain C, Rodriguez JA, et al. Hyperhomocysteinemia in liver cirrhosis: mechanisms and role in vascular and hepatic fibrosis. Hypertension 2001;38:1217-21.
    • (2001) Hypertension , vol.38 , pp. 1217-1221
    • Garcia-Tevijano, E.R.1    Berasain, C.2    Rodriguez, J.A.3
  • 11
    • 0032080212 scopus 로고    scopus 로고
    • Time course of total cysteine, glutathione and homocysteine in plasma of patients with chronic hepatitis C treated with interferon-α with and without supplementation with N-acetylcysteine
    • Bernard M-C, Jubker E, Hettinger A, Lauterberg BH. Time course of total cysteine, glutathione and homocysteine in plasma of patients with chronic hepatitis C treated with interferon-α with and without supplementation with N-acetylcysteine. J Hepatol 1998;28:751-5.
    • (1998) J Hepatol , vol.28 , pp. 751-755
    • Bernard, M.-C.1    Jubker, E.2    Hettinger, A.3    Lauterberg, B.H.4
  • 12
    • 0033812319 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in liver transplant recipients: Prevalence and multivariate analysis of predisposing factors
    • Herrero JI, Quiroga J, Sangro B, et al. Hyperhomocysteinemia in liver transplant recipients: prevalence and multivariate analysis of predisposing factors. Liver Transpl 2000;6:614-8.
    • (2000) Liver Transpl , vol.6 , pp. 614-618
    • Herrero, J.I.1    Quiroga, J.2    Sangro, B.3
  • 13
    • 0034776653 scopus 로고    scopus 로고
    • Determinants of increased plasma homocysteine in 221 stable liver transplant patients
    • Fernandez-Miranda C, Danz M, de la Calle A, et al. Determinants of increased plasma homocysteine in 221 stable liver transplant patients. Clin Chem 2001;47:2037-40.
    • (2001) Clin Chem , vol.47 , pp. 2037-2040
    • Fernandez-Miranda, C.1    Danz, M.2    De La Calle, A.3
  • 14
    • 0023902956 scopus 로고
    • S-adenosyl-L-methionine synthase and phospholipid methyltransferase are inhibited in human cirrhosis
    • Duce AM, Ortiz P, Cabrero C, Mato JM. S-adenosyl-L-methionine synthase and phospholipid methyltransferase are inhibited in human cirrhosis. Hepatology 1988;8:65-8.
    • (1988) Hepatology , vol.8 , pp. 65-68
    • Duce, A.M.1    Ortiz, P.2    Cabrero, C.3    Mato, J.M.4
  • 15
    • 0033658966 scopus 로고    scopus 로고
    • Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma
    • Avila MA, Berasain C, Torres L, et al. Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma. J Hepatol 2000;33:907-14.
    • (2000) J Hepatol , vol.33 , pp. 907-914
    • Avila, M.A.1    Berasain, C.2    Torres, L.3
  • 17
  • 18
    • 0030188563 scopus 로고    scopus 로고
    • The oxidant stress of hyperhomocyst(e)inemia
    • Loscalzo J. The oxidant stress of hyperhomocyst(e)inemia. J Clin Invest 1996;98:5-7.
    • (1996) J Clin Invest , vol.98 , pp. 5-7
    • Loscalzo, J.1
  • 20
    • 0029918034 scopus 로고    scopus 로고
    • Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation
    • Halsted CH, Villanueva J, Chandler CJ, et al. Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation. Hepatology 1996;23:497-505.
    • (1996) Hepatology , vol.23 , pp. 497-505
    • Halsted, C.H.1    Villanueva, J.2    Chandler, C.J.3
  • 21
    • 0345035265 scopus 로고    scopus 로고
    • Induction of TIMP-1 expression in rat hepatocyte stellate cells and hepatocytes: A new role for homocysteine in liver fibrosis
    • Torres L, Garcia-Trevijano ER, Rodriguez JA, et al. Induction of TIMP-1 expression in rat hepatocyte stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis. Biochim Biophys Acta 1999;1455:12-22.
    • (1999) Biochim Biophys Acta , vol.1455 , pp. 12-22
    • Torres, L.1    Garcia-Trevijano, E.R.2    Rodriguez, J.A.3
  • 24
    • 0028025333 scopus 로고
    • Metabolism of energy-yielding substrates in patients with liver cirrhosis
    • Müller MJ. Metabolism of energy-yielding substrates in patients with liver cirrhosis. Clin Investig 1994;72:568-79.
    • (1994) Clin Investig , vol.72 , pp. 568-579
    • Müller, M.J.1
  • 25
    • 0026533946 scopus 로고
    • High-performance liquid chomatographic method with fluorescence detection for the determination of total homocyst(e)ine in plasma
    • Fermo I, Arcelloni C, De Vecchi E, Vigano S, Paroni R. High-performance liquid chomatographic method with fluorescence detection for the determination of total homocyst(e)ine in plasma. J Chromatogr 1992;593:171-6.
    • (1992) J Chromatogr , vol.593 , pp. 171-176
    • Fermo, I.1    Arcelloni, C.2    De Vecchi, E.3    Vigano, S.4    Paroni, R.5
  • 27
    • 0030022202 scopus 로고    scopus 로고
    • The effect of reduced glomerular filtration rate on plasma total homocysteine concentrations
    • Arnadottir M, Hultberg B, Nilsson-Ehle P, Thysell H. The effect of reduced glomerular filtration rate on plasma total homocysteine concentrations. Scand J Clin Lab Invest 1996;56:41-6.
    • (1996) Scand J Clin Lab Invest , vol.56 , pp. 41-46
    • Arnadottir, M.1    Hultberg, B.2    Nilsson-Ehle, P.3    Thysell, H.4
  • 29
    • 0020366008 scopus 로고
    • The effects of nitrous oxide on cobalamins, folates, and on related events
    • Chanarin I. The effects of nitrous oxide on cobalamins, folates, and on related events. Crit Rev Toxicol 1982;10:179-213.
    • (1982) Crit Rev Toxicol , vol.10 , pp. 179-213
    • Chanarin, I.1
  • 30
    • 0033547641 scopus 로고    scopus 로고
    • An alternative viewpoint of homocysteine
    • Dudman NPB. An alternative viewpoint of homocysteine. Lancet 1999;354:2072-4.
    • (1999) Lancet , vol.354 , pp. 2072-2074
    • Dudman, N.P.B.1
  • 33
    • 0024351118 scopus 로고
    • Fasting plasma homocysteine as a sensitive parameter to antifolate effect. A study on psoriasis patients receiving low-dose methotrexate treatment
    • Refsum H, Helland S, Ueland PM. Fasting plasma homocysteine as a sensitive parameter to antifolate effect. A study on psoriasis patients receiving low-dose methotrexate treatment. Clin Pharmacol Ther 1989;46:510-20.
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 510-520
    • Refsum, H.1    Helland, S.2    Ueland, P.M.3
  • 34
    • 0026096815 scopus 로고
    • Plasma homocysteine in children with acute lymphoblastic leukemia. Changes during a chemotherapeutic regimen including methotrexate
    • Refsum H, Wesenberg F, Ueland PM. Plasma homocysteine in children with acute lymphoblastic leukemia. Changes during a chemotherapeutic regimen including methotrexate. Cancer Res 1991;51:828-35.
    • (1991) Cancer Res , vol.51 , pp. 828-835
    • Refsum, H.1    Wesenberg, F.2    Ueland, P.M.3
  • 35
    • 0030966942 scopus 로고    scopus 로고
    • Abnormal homocysteine metabolism in rheumatoid arthritis
    • Roubenoff R, Dellaripa P, Nadeau MR, et al. Abnormal homocysteine metabolism in rheumatoid arthritis. Arthr Rheum 1997;40:718-22.
    • (1997) Arthr Rheum , vol.40 , pp. 718-722
    • Roubenoff, R.1    Dellaripa, P.2    Nadeau, M.R.3
  • 36
    • 0030603334 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for atherothrombotic events in systemic lupus erythematosus
    • Petri M, Roubenoff R, Dallal GE, Nadeau MR, Selhub J, Rosenberg IH. Plasma homocysteine as a risk factor for atherothrombotic events in systemic lupus erythematosus. Lancet 1996;348:1120-4.
    • (1996) Lancet , vol.348 , pp. 1120-1124
    • Petri, M.1    Roubenoff, R.2    Dallal, G.E.3    Nadeau, M.R.4    Selhub, J.5    Rosenberg, I.H.6
  • 37
    • 0028177431 scopus 로고
    • Effects of age, lipoproteins, and hemostatic parameters on the role of homocystein(e)mia as a cardiovascular risk factor in men
    • Von Eckardstein A, Malinow MR, Upson B, et al. Effects of age, lipoproteins, and hemostatic parameters on the role of homocystein(e)mia as a cardiovascular risk factor in men. Arterioscler Thromb 1994;14:460-4.
    • (1994) Arterioscler Thromb , vol.14 , pp. 460-464
    • Von Eckardstein, A.1    Malinow, M.R.2    Upson, B.3
  • 40
  • 41
    • 0018870054 scopus 로고
    • Hydrolysis of pyridoxal 5-phosphate in plasma in conditions with raised alkaline phosphatase
    • Anderson BB, O'Brien H, Griffin GE, Mollin DL. Hydrolysis of pyridoxal 5-phosphate in plasma in conditions with raised alkaline phosphatase. Gut 1980;21:192-4.
    • (1980) Gut , vol.21 , pp. 192-194
    • Anderson, B.B.1    O'Brien, H.2    Griffin, G.E.3    Mollin, D.L.4
  • 43
    • 0021358095 scopus 로고
    • Relationship between pyridoxal 5′-phosphate deficiency and aminotransferase levels in alcoholic hepatitis
    • Diehl AM, Potter J, Boitnott J, Van Duyn MA, Herlong HF, Mezey E. Relationship between pyridoxal 5′-phosphate deficiency and aminotransferase levels in alcoholic hepatitis. Gastroenterology 1984;86:632-6.
    • (1984) Gastroenterology , vol.86 , pp. 632-636
    • Diehl, A.M.1    Potter, J.2    Boitnott, J.3    Van Duyn, M.A.4    Herlong, H.F.5    Mezey, E.6
  • 44
    • 0023902956 scopus 로고
    • S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis
    • Martin-Duce AM, Ortiz P, Cabrero C, Mato JM. S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis. Hepatology 1988;8:65-8.
    • (1988) Hepatology , vol.8 , pp. 65-68
    • Martin-Duce, A.M.1    Ortiz, P.2    Cabrero, C.3    Mato, J.M.4


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