Synthesis of 5,12-dioxocyclam nickel (II) complexes having quinoxaline substituents at the 6 and 13 positions as potential DNA bis-intercalating and cleaving agents

Journal of Organic Chemistry

Volumn 68, Issue 11, 2003, Pages 4179-4188

  Hegedus, Louis S ^a   Greenberg, Marc M ^b   Wendling, Jory J ^a,b   Bullock, Joseph P ^a,b  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

QUINOXALINE MOIETIES;

COMPLEXATION; DNA; OXIDATION; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

NICKEL COMPOUNDS;

5,12 DIOXOCYCLAM DERIVATIVE; CARBENE; CHROMIUM; CYCLAM DERIVATIVE; INTERCALATING AGENT; NICKEL COMPLEX; PLASMID DNA; QUINOXALINE DERIVATIVE; TRIOSTIN A; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DIMERIZATION; DNA CLEAVAGE; DRUG SYNTHESIS; INTERCALATION COMPLEX; OXIDATION; PROTON NUCLEAR MAGNETIC RESONANCE;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DNA; HETEROCYCLIC COMPOUNDS; INTERCALATING AGENTS; MOLECULAR STRUCTURE; NICKEL; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; PLASMIDS; QUINOXALINES; STEREOISOMERISM; SULFURIC ACIDS;

EID: 0038441601     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo020708r     Document Type: Article

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