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Volumn 5, Issue 1, 2003, Pages 73-78

Efficient synthesis of 2,4-disubstituted 1,2,4-benzothiadiazin-3-one 1,1-dioxides on solid support

Author keywords

[No Author keywords available]

Indexed keywords

2 NITROBENZENESULFONAMIDE; 2,4 DISUBSTITUTED 1,24 BENZOTHIADIAZIN 3 ONE 1,1 DIOXIDE; CARBONYLDIIMIDAZOLE; IMIDAZOLE DERIVATIVE; OXIDE; SULFONAMIDE; UNCLASSIFIED DRUG; BENZOTHIADIAZINE DERIVATIVE; RESIN;

EID: 0038386029     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc020056k     Document Type: Article
Times cited : (19)

References (32)
  • 1
    • 7044263277 scopus 로고    scopus 로고
    • Reviews: (a) Thompson, L. A.; Ellman, J. A. Chem. Rev. 1996, 96, 555. (b) Booth, S.; Hermkens, P. H. H.; Ottenheijm, H. C. J.; Rees, D. C. Tetrahedron 1998, 54, 15385.
    • (1996) Chem. Rev. , vol.96 , pp. 555
    • Thompson, L.A.1    Ellman, J.A.2
  • 13
    • 0141600381 scopus 로고    scopus 로고
    • Fujisawa Pharmaceutical Co. Benzothiadiazine Compounds, and Pharmaceutical Composition Comprising the Same. EP268990, 1988. (b) Chinoin Gyogyszer es Vegyeszet. Prolylendopeptidase Inhibitors. WO9707116, 1997.
    • Fujisawa Pharmaceutical Co. Benzothiadiazine Compounds, and Pharmaceutical Composition Comprising the Same. EP268990, 1988. (b) Chinoin Gyogyszer es Vegyeszet. Prolylendopeptidase Inhibitors. WO9707116, 1997.
  • 22
    • 0141712071 scopus 로고    scopus 로고
    • 4-(4-Formyl-3-methoxyphenoxy)butyryl AM resin (100-200 mesh, loading 0. 53 mmol/g) was purchased from Novabiochem
    • 4-(4-Formyl-3-methoxyphenoxy)butyryl AM resin (100-200 mesh, loading 0. 53 mmol/g) was purchased from Novabiochem (http://www.nova.ch).
  • 23
    • 0141712072 scopus 로고    scopus 로고
    • note
    • The following amines were used for this reductive amination and subsequently acylated with 2 to give the corresponding 1,2,4-benzothiadiazin-3-one 1,1-dioxides: isopropylamine, allylamine, cyclobutylamine, furfurylamine, piperonylamine, phenethylamine, and 2,2-diphenylethylamine.
  • 31
    • 0141823389 scopus 로고    scopus 로고
    • FlexChem rotating oven, model 404
    • FlexChem rotating oven, model 404, http://www.robsci.com.
  • 32
    • 0141823390 scopus 로고    scopus 로고
    • Genevac HT-8 is available from Genevac Limited (Farthing Road, Ipswich, IP1 5AP, U.K.)
    • Genevac HT-8 is available from Genevac Limited (Farthing Road, Ipswich, IP1 5AP, U.K.).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.