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Volumn 37, Issue 17, 1996, Pages 2943-2946

Solid phase synthesis of pyrroles derived from a four component condensation

Author keywords

[No Author keywords available]

Indexed keywords

PYRROLE DERIVATIVE;

EID: 0029940759     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00365-6     Document Type: Article
Times cited : (96)

References (30)
  • 3
    • 85030188646 scopus 로고
    • International Patent WO 95192566
    • (a) Armstrong, R. W. International Patent WO 95192566, 1995.
    • (1995)
    • Armstrong, R.W.1
  • 17
    • 84917967252 scopus 로고
    • (a) 2-Pyridylisocyanide: Ugi, I.; Fetzer, U.; Unterstenhoefer, G.; Behrenz, W.; Frohberger, P. E.; Scheinpflug, H. Patent Fr. 1,384,209 Jan. 4, 1965; Chem. Abstr. 1965, 63, 6924e.
    • (1965) Chem. Abstr. , vol.63
  • 18
    • 0001223891 scopus 로고
    • (b) Phenylisocyanide: Walborsky, H. M.; Ronman, P. J. Org. Chem. 1978, 43, 731. Both isocyanides are prepared in one step from commercially available formamides.
    • (1978) J. Org. Chem. , vol.43 , pp. 731
    • Walborsky, H.M.1    Ronman, P.2
  • 19
    • 85030188681 scopus 로고    scopus 로고
    • note
    • Calculation based upon commercially available 1° amines, aldehydes, carboxylic acids and alkynes contained in the ACD database, MDL Information Systems. Traditionally, N-acyl-N-alkyl-a-amino amides have been prepared on solid suport via reductive amination of an a-amino acid with an aldehyde followed by acylation of the resulting 2° amine. Since a limited number of a-amino acids are commercially available, this approach drastically reduces the final library size.
  • 26
    • 85030189246 scopus 로고    scopus 로고
    • note
    • 2NH. These results as well as subsequent functional transformations of these intermediates will be reported shortly.
  • 30
    • 85030197643 scopus 로고    scopus 로고
    • note
    • 13C NMR and high resolution MS.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.