Insulin inhibition of the proteasome is dependent on degradation of insulin by insulin-degrading enzyme

Journal of Endocrinology

Volumn 177, Issue 3, 2003, Pages 399-405

  Bennett, R G ^a,b   Fawcett, J ^c,d   Kruer, M C ^c   Duckworth, W C ^c,d,e   Hamel, F G ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^c CARL T HAYDEN VA MEDICAL CENTER   (United States)

^d ARIZONA STATE UNIVERSITY   (United States)

^e UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN ASPART; INSULIN DERIVATIVE; INSULIN GLARGINE; INSULIN LISPRO; INSULINASE; IODINE 125; PROTEASOME; PROTEASOME INHIBITOR;

ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; HYPOTHESIS; INSULIN DEGRADATION; INSULIN DEPENDENT DIABETES MELLITUS; ISOTOPE LABELING; MALE; MUSCLE MASS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; RAT;

ANIMALS; CYSTEINE ENDOPEPTIDASES; DEPRESSION, CHEMICAL; DIABETES MELLITUS, TYPE 1; HYPOGLYCEMIC AGENTS; INSULIN; INSULYSIN; IODINE RADIOISOTOPES; MULTIENZYME COMPLEXES; MUSCLE, SKELETAL; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0038377693     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1770399     Document Type: Article

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