Rsp5p is required for ER bound Mga2p120 polyubiquitination and release of the processed/tethered transactivator Mga2p90

Current Biology

Volumn 13, Issue 14, 2003, Pages 1227-1233

  Shcherbik, Natalia ^a   Zoladek, Teresa ^b   Nickels, Joseph T ^c   Haines, Dale S ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0038376459     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(03)00457-3     Document Type: Article

References (10)

1. Zhang, S., Skalsky, Y., and Garfinkel, D.J. (1999). MGA2 or SPT23 is required for transcription of the delta9 fatty acid desaturase gene, OLE1, and nuclear membrane integrity in Saccharomyces cerevisiae. Genetics 151, 473-483.
2. Hoppe, T., Matuschewski, K., Rape, M., Schlenker, S., Ulrich, H.D., and Jentsch, S. (2000). Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing. Cell 102, 577-598.
3. Rape, M., Hoppe, T., Gorr, I., Kalocay, M., Richly, H., and Jentsch, S. (2001). Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone. Cell 107, 667-677.
4. Shcherbik, N., Kumar, S., and Haines, D.S. (2002). Substrate proteolysis is inhibited by dominant-negative Nedd4 and Rsp5 mutants harboring alterations in WW domain 1. J. Cell Sci. 115, 1041-1048.
5. Hitchcock, A.L., Krebber, H., Frietze, S., Lin, A., Latterich, M., and Silver, P.A. (2001). The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol. Biol. Cell 12, 3226-3241.
6. Haynes, C.M., Caldwell, S., and Cooper, A.A. (2002). An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport. J. Cell Biol. 158, 91-101.
7. Bays, N.W., and Hampton, R.Y. (2002). Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr. Biol. 12, 366-371.
8. Fleming, J.A., Lightcap, E.S., Sadis, S., Thoroddsen, V., Bulawa, C.E., and Blackman, R.K. (2002). Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341. Proc. Natl. Acad. Sci. USA 99, 1461-1466.
9. Lin, L., DeMartino, G.N., and Greene, W.C. (2000). Cotranslational dimerization of the Rel homology domain of NK-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production. EMBO J. 19, 4712-4722.
10. Chang, A., Cheang, S., Espanel, X., and Sudol, M. (2000). Rsp5 WW domains interact directly with the carboxyl-terminal domain of RNA polymerase II. J. Biol. Chem. 275, 20562-20571.