Design and synthesis of some substituted 1H-pyrazolyl-oxazolidines or 1H-pyrazolyl-thiazolidines as anti-inflammatory-antimicrobial agents

Archiv der Pharmazie

Volumn 336, Issue 2, 2003, Pages 111-118

  Bekhit, Adnan A ^a   Fahmy, Hesham T Y ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Anti inflammatory; Antimicrobial; Oxazolidine; Pyrazole; Thiazolidine

Indexed keywords

2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 3 (TERT BUTYLOXYCARBONYL) 5 METHYLTHIAZOLIDINE 4 CARBOXAMIDE; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 3 (TERT BUTYLOXYCARBONYL) 5 METHYLTHIAZOLIDINE 4 CARBOXYLIC ACID; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 3 (TERT BUTYLOXYCARBONYL) 5,5 DIMETHYLTHIAZOLIDINE 4 CARBOXAMIDE; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 3 (TERT BUTYLOXYCARBONYL) 5,5 DIMETHYLTHIAZOLIDINE 4 CARBOXYLIC ACID; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 3 (TERT BUTYLOXYCARBONYL)OXAZOLIDINE 4 CARBOXAMIDE; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 3 (TERT BUTYLOXYCARBONYL)OXAZOLIDINE 4 CARBOXYLIC ACID; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 5 METHYLTHIAZOLIDINE 4 CARBOXAMIDE; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 5 METHYLTHIAZOLIDINE 4 CARBOXYLIC ACID; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL] 5,5 DIMETHYLTHIAZOLIDINE 4 CARBOXYLIC ACID; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL]OXAZOLIDINE 4 CARBOXAMIDE; 2 [3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOL 4 YL]OXAZOLIDINE 4 CARBOXYLIC ACID; 3 (5 BROMO 2 THIENYL) 1 PHENYL 1H PYRAZOLE 4 CARBOXALDEHYDE; AMIDE; AMMONIUM DERIVATIVE; AMPICILLIN; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; CHLORIDE; CLOTRIMAZOLE; CYSTEINE; DIHYDROSTREPTOMYCIN; DIOXANE; INDOMETACIN; OXAZOLIDINE DERIVATIVE; PENICILLAMINE; PENICILLIN G; PYRAZOLE DERIVATIVE; SERINE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DIASTEREOISOMER; DRUG DESIGN; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GRANULOMA; LD 50; MALE; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ULCEROGENESIS; VILSMEIER HAACK REACTION;

ACUTE TOXICITY TESTS; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CANDIDA ALBICANS; DRUG DESIGN; ESCHERICHIA COLI; INFUSIONS, PARENTERAL; LETHAL DOSE 50; MALE; MICE; OXAZOLES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; STAPHYLOCOCCUS AUREUS; STOMACH ULCER; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 0038373598     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200390007     Document Type: Article

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