Studies on anti-inflammatory agents. VI. Synthesis and pharmacological properties of 2,3-diarylthiophenes

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 2, 1998, Pages 279-286

  Tsuji, Kiyoshi ^a   Nakamura, Katsuya ^a   Ogino, Takashi ^a   Konishi, Nobukiyo ^a   Tojo, Takashi ^a   Ochi, Takehiro ^a   Seki, Nobuo ^a   Matsuo, Masaaki ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

2,3 diarylthiophene; Analgesic activity; Anti inflammatory agent; Antirheumatic activity; Structure activity relationship

Indexed keywords

2 (4 FLUOROPHENYL) 3 [4 (METHYLSULFONYL)PHENYL] 5 (TRIFLUOROMETHYL)THIOPHENE; 2,3 DIARYLTHIOPHENE DERIVATIVE; 4' ACETYL 2' (2,4 DIFLUOROPHENOXY)METHANESULFONANILIDE; 5 BROMO 2 [4 (METHYLAMINO)PHENYL] 3 [4 (METHYLSULFINYL)PHENYL]THIOPHENE; FR 115068; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYPERALGESIA; INFLAMMATION; MALE; MOUSE; NONHUMAN; RHEUMATOID ARTHRITIS; STRUCTURE ACTIVITY RELATION;

EID: 0031917154     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.279     Document Type: Article

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