-
1
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001;344:1031-1037.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
2
-
-
0035810142
-
Activity of a specific inhibitor of the BCR/ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H et al. Activity of a specific inhibitor of the BCR/ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001;344:1038-1042.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
-
3
-
-
0034161460
-
Induction of resistance to the Abelson inhibitor ST1571 in human leukemic cells through gene amplification
-
le Coutre P, Tassi E, Varella-Garcia M et al. Induction of resistance to the Abelson inhibitor ST1571 in human leukemic cells through gene amplification. Blood 2000;95:1758-1766.
-
(2000)
Blood
, vol.95
, pp. 1758-1766
-
-
Le Coutre, P.1
Tassi, E.2
Varella-Garcia, M.3
-
4
-
-
0034210577
-
Mechanism of resistance to the ABL tyrosine kinase inhibitor ST1571 in BCR/ABL-transformed hematopoietic cell lines
-
Weisberg E, Griffin JD. Mechanism of resistance to the ABL tyrosine kinase inhibitor ST1571 in BCR/ABL-transformed hematopoietic cell lines. Blood 2000;95:3498-3505.
-
(2000)
Blood
, vol.95
, pp. 3498-3505
-
-
Weisberg, E.1
Griffin, J.D.2
-
5
-
-
0034254368
-
Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor ST1571: Diverse mechanisms of resistance
-
Mahon FX, Deininger MW, Schultheis B et al. Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor ST1571: diverse mechanisms of resistance. Blood 2000;96:1070-1079.
-
(2000)
Blood
, vol.96
, pp. 1070-1079
-
-
Mahon, F.X.1
Deininger, M.W.2
Schultheis, B.3
-
6
-
-
0035800507
-
Clinical resistance to ST1571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K et al. Clinical resistance to ST1571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001;293:876-880.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
7
-
-
0036566540
-
High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (ST1571) resistance
-
Branford S, Rudzki Z, Walsh S et al. High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (ST1571) resistance. Blood 2002;99:3472-3475.
-
(2002)
Blood
, vol.99
, pp. 3472-3475
-
-
Branford, S.1
Rudzki, Z.2
Walsh, S.3
-
8
-
-
0034684075
-
Role of alphal acid glycoprotein in the in vivo resistance of human BCR-ABL(+) leukemic cells to the abl inhibitor ST1571
-
Gambacorti-Passerini C, Barni R, le Coutre P et al. Role of alphal acid glycoprotein in the in vivo resistance of human BCR-ABL(+) leukemic cells to the abl inhibitor ST1571. J Natl Cancer Inst 2002;92:1641-1650.
-
(2002)
J Natl Cancer Inst
, vol.92
, pp. 1641-1650
-
-
Gambacorti-Passerini, C.1
Barni, R.2
Le Coutre, P.3
-
9
-
-
0020974381
-
Establishment of a Ph1 chromosomepositive cell line from chronic myelogenous leukemia in blast crisis
-
Kubonishi I, Miyoshi I. Establishment of a Ph1 chromosomepositive cell line from chronic myelogenous leukemia in blast crisis. Int J Cell Cloning 1983;1:105-117.
-
(1983)
Int J Cell Cloning
, vol.1
, pp. 105-117
-
-
Kubonishi, I.1
Miyoshi, I.2
-
10
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
11
-
-
0032570768
-
Regulation of NF-E2 activity in erythroleukemia cell differentiation
-
Nagai T, Igarashi K, Akasaka J et al. Regulation of NF-E2 activity in erythroleukemia cell differentiation. J Biol Chem 1998;273:5358-5365.
-
(1998)
J Biol Chem
, vol.273
, pp. 5358-5365
-
-
Nagai, T.1
Igarashi, K.2
Akasaka, J.3
-
12
-
-
18244404089
-
Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells
-
Ohmine K, Ota J, Ueda M et al. Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells. Oncogene 2001;20:8249-8257.
-
(2001)
Oncogene
, vol.20
, pp. 8249-8257
-
-
Ohmine, K.1
Ota, J.2
Ueda, M.3
-
13
-
-
0027459279
-
Expression of messenger RNAs for complement inhibitors in human tissues and tumors
-
Kumar S, Vinci JM, Pytel BA et al. Expression of messenger RNAs for complement inhibitors in human tissues and tumors. Cancer Res 1993;53:348-353.
-
(1993)
Cancer Res
, vol.53
, pp. 348-353
-
-
Kumar, S.1
Vinci, J.M.2
Pytel, B.A.3
-
14
-
-
0035210658
-
Imatinib mesylate: Clinical results in Philadelphia chromosome-positive leukemias
-
Kantarjian HM, Talpaz M, Imatinib mesylate: clinical results in Philadelphia chromosome-positive leukemias. Semin Oncol 2001;28(suppl 17):9-18.
-
(2001)
Semin Oncol
, vol.28
, Issue.SUPPL. 17
, pp. 9-18
-
-
Kantarjian, H.M.1
Talpaz, M.2
-
15
-
-
0034569415
-
Multidrug resistance of acute leukemia and a strategy to overcome it
-
Motoji T, Motomura S, Wang YH. Multidrug resistance of acute leukemia and a strategy to overcome it. Int J Hematol 2000;72:418-424.
-
(2000)
Int J Hematol
, vol.72
, pp. 418-424
-
-
Motoji, T.1
Motomura, S.2
Wang, Y.H.3
-
16
-
-
0033179095
-
Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-gp, MRP1, and LRP in acute myeloid leukemia: A southwest oncology group study
-
Leith CP, Kopecky KJ, Chen IM et al. Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-gp, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study. Blood 1999;94:1086-1099.
-
(1999)
Blood
, vol.94
, pp. 1086-1099
-
-
Leith, C.P.1
Kopecky, K.J.2
Chen, I.M.3
-
17
-
-
0034777851
-
Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia
-
van der Kolk DM, de Vries EG, Noordhoek L et al. Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia. Leukemia 2001;15:1544-1553.
-
(2001)
Leukemia
, vol.15
, pp. 1544-1553
-
-
Van der Kolk, D.M.1
De Vries, E.G.2
Noordhoek, L.3
-
18
-
-
0032605815
-
The lung resistance protein (LRP) predicts poor outcome in acute myeloid leukemia
-
Pirker R, Pohl G, Stranzl T et al. The lung resistance protein (LRP) predicts poor outcome in acute myeloid leukemia. Adv Exp Med Biol 1999;457:133-139.
-
(1999)
Adv Exp Med Biol
, vol.457
, pp. 133-139
-
-
Pirker, R.1
Pohl, G.2
Stranzl, T.3
-
19
-
-
0024212303
-
Molecular cloning of two types of GAP complementary DNA from human placenta
-
Trahey M, Wong G, Halenbeck R et al. Molecular cloning of two types of GAP complementary DNA from human placenta. Science 1988;242:1697-1700.
-
(1988)
Science
, vol.242
, pp. 1697-1700
-
-
Trahey, M.1
Wong, G.2
Halenbeck, R.3
-
20
-
-
0033529620
-
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
-
Maekawa M, Ishizaki T, Boku S et al. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 1999;285:895-898.
-
(1999)
Science
, vol.285
, pp. 895-898
-
-
Maekawa, M.1
Ishizaki, T.2
Boku, S.3
-
22
-
-
0035865137
-
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility
-
Sahai E, Olson MF, Marshall CJ. Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility. EMBO J 2001;20:755-766.
-
(2001)
EMBO J
, vol.20
, pp. 755-766
-
-
Sahai, E.1
Olson, M.F.2
Marshall, C.J.3
-
23
-
-
0028903247
-
An essential role for Rac in Ras transformation
-
Qiu RG, Chen J, Kim D et al. An essential role for Rac in Ras transformation. Nature 1995;374:457-459.
-
(1995)
Nature
, vol.374
, pp. 457-459
-
-
Qiu, R.G.1
Chen, J.2
Kim, D.3
-
26
-
-
0025821494
-
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
-
Mucenski ML, McLain K, Kier AB et al. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 1991;65:677-689.
-
(1991)
Cell
, vol.65
, pp. 677-689
-
-
Mucenski, M.L.1
McLain, K.2
Kier, A.B.3
-
27
-
-
0029839024
-
Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain
-
Miglarese MR, Richardson AF, Aziz N et al. Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain. J Biol Chem 1996;271:22697-22705.
-
(1996)
J Biol Chem
, vol.271
, pp. 22697-22705
-
-
Miglarese, M.R.1
Richardson, A.F.2
Aziz, N.3
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