Interleukin-1 receptor antagonist is associated with fat distribution in endogenous Cushing's syndrome: A longitudinal study

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 4, 2003, Pages 1492-1496

  Ueland, Thor ^a   Kristo, C ^a   Godang, K ^a   Aukrust, P ^a   Bollerslev, J ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; LEPTIN;

ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; CONTROLLED STUDY; CUSHING SYNDROME; FEMALE; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LINEAR REGRESSION ANALYSIS; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; WEIGHT GAIN;

ADIPOSE TISSUE; ADULT; BODY COMPOSITION; C-PEPTIDE; CUSHING SYNDROME; FEMALE; HUMANS; HYDROCORTISONE; INSULIN; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; LEPTIN; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; SIALOGLYCOPROTEINS;

EID: 0038360797     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-021030     Document Type: Article

References (37)

1. Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS 1996 Role of leptin in the neuroendocrine response to fasting. Nature 382:250-252
2. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P 1995 Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549
3. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM 1995 Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546
4. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F 1995 Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543
5. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S 1995 Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161
6. Auwerx J, Staels B 1998 Leptin. Lancet 351:737-742
7. Murakami T, Iida M, Shima K 1995 Dexamethasone regulates obese expression in isolated rat adipocytes. Biochem Biophys Res Commun 214:1260-1267
8. De Vos P, Saladin R, Auwerx J, Staels B 1995 Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem 270:15958-15961
9. Yoshida T, Hayashi M, Monkawa T, Saruta T 1996 Regulation of obese mRNA expression by hormonal factors in primary cultures of rat adipocytes. Eur J Endocrinol 135:619-625
10. Saladin R, De Vos P, Guerre-Millo M, Leturque A, Girard J, Staels B, Auwerx J 1995 Transient increase in obese gene expression after food intake or insulin administration. Nature 377:527-529
11. Schafroth U, Godang K, Ueland T, Berg JP, Bollerslev J 2000 Leptin levels in relation to body composition and insulin concentration in patients with endogenous Cushing's syndrome compared to controls matched for body mass index. J Endocrinol Invest 23:349-355
12. Wajchenberg BL, Bosco A, Marone MM, Levin S, Rocha M, Lerario AC, Nery M, Goldman J, Liberman B 1995 Estimation of body fat and lean tissue distribution by dual energy x-ray absorptiometry and abdominal body fat evaluation by computed tomography in Cushing's disease. J Clin Endocrinol Metab 80:2791-2794
13. Yanovski JA, Cutler Jr GB 1994 Glucocorticoid action and the clinical features of Cushing's syndrome. Endocrinol Metab Clin North Am 23:487-509
14. Ross EJ, Marshall-Jones P, Friedman M 1996 Cushing's syndrome: diagnostic criteria. Q J Med 35:149-192
15. Leal-Cerro A, Considine RV, Peino R, Venegas E, Astorga R, Casanueva FF, Dieguez C 1996 Serum immunoreactive-leptin levels are increased in patients with Cushing's syndrome. Horm Metab Res 28:711-713
16. Halleux CM, Servais I, Reul BA, Detry R, Brichard SM 1998 Multihormonal control of ob gene expression and leptin secretion from cultured human visceral adipose tissue: increased responsiveness to glucocorticoids in obesity. J Clin Endocrinol Metab 83:902-910
17. Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte Jr D 1996 Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat Med 2:589-593
18. Luheshi GN, Gardner JD, Rushforth DA, Loudon AS, Rothwell NJ 1999 Leptin actions on food intake and body temperature are mediated by IL-1. Proc Natl Acad Sci USA 96:7047-7052
19. Besedovsky H, del Rey A, Sorkin E, Dinarello CA 1986 Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 233:652-654
20. Sapolsky R, Rivier C, Yamamoto G, Plotsky P, Vale W 1987 Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor. Science 238:522-524
21. Cizza G, Lotsikas AJ, Licinio J, Gold PW, Chrousos GP 1997 Plasma leptin levels do not change in patients with Cushing's disease shortly after correction of hypercortisolism. J Clin Endocrinol Metab 82:2747-2750
22. Masuzaki H, Ogawa Y, Hosoda K, Miyawaki T, Hanaoka I, Hiraoka J, Yasuno A, Nishimura H, Yoshimasa Y, Nishi S, Nakao K 1997 Glucocorticoid regulation of leptin synthesis and secretion in humans: elevated plasma leptin levels in Cushing's syndrome. J Clin Endocrinol Metab 82:2542-2547
23. Pirlich M, Biering H, Gerl H, Ventz M, Schmidt B, Ertl S, Lochs H 2002 Loss of body cell mass in Cushing's syndrome: effect of treatment. J Clin Endocrinol Metab 87:1078-1084
24. Godang K, Ueland T, Bollerslev J 1999 Decreased bone area, bone mineral content, formative markers, and increased bone resorptive markers in endogenous Cushing's syndrome. Eur J Endocrinol 141:126-131
25. Lonn L, Kvist H, Ernest I, Sjostrom L 1994 Changes in body composition and adipose tissue distribution after treatment of women with Cushing's syndrome. Metabolism 43:1517-1522
26. Harris RB 2000 Leptin - much more than a satiety signal. Annu Rev Nutr 20:45-75
27. van Dielen FM, van't Veer C, Buurman WA, Greve JW 2002 Leptin and soluble leptin receptor levels in obese and weight-losing individuals. J Clin Endocrinol Metab 87:1708-1716
28. Meier CA, Bobbioni E, Gabay C, Assimacopoulos-Jeannet F, Golay A, Dayer JM 2002 IL-1 receptor antagonist serum levels are increased in human obesity: a possible link to the resistance to leptin? J Clin Endocrinol Metab 87:1184-1188
29. Baronzio G, Zambelli A, Comi D, Barlocco A, Baronzio A, Marchesi P, Gramaglia A, Castiglioni E, Mafezzoni A, Beviglia E, Crespi F, Cargnel AI, Pravettoni G 1999 Proinflammatory and regulatory cytokine levels in AIDS cachexia. In Vivo 13:499-502
30. Bunout D, Munoz C, Lopez M, de la Maza MP, Schlesinger L, Hirsch S, Pettermann M 1996 Interleukin 1 and tumor necrosis factor in obese alcoholics compared with normal-weight patients. Am J Clin Nutr 63:373-376
31. Mito N, Hiyoshi T, Hosoda T, Kitada C, Sato K 2002 Effect of obesity and insulin on immunity in non-insulin-dependent diabetes mellitus. Eur J Clin Nutr 56:347-351
32. Arzt E, Sauer J, Pollmacher T, Labeur M, Holsboer F, Reul JM, Stalla GK 1994 Glucocorticoids suppress interleukin-1 receptor antagonist synthesis following reduction by endotoxin. Endocrinology 134:672-677
33. Sauer J, Castren M, Hopfner U, Holsboer F, Stalla GK, Arzt E 1996 Inhibition of lipopolysaccharide-induced monocyte interleukin-1 receptor antagonist synthesis by cortisol: involvement of the mineralocorticoid receptor. J Clin Endocrinol Metab 81:73-79
34. Watanobe H, Tamura T, Habu S, Kakizaki Y, Kohsaka A, Suda T 1998 Measurement of cytokines in the cavernous sinus plasma from patients with Cushing's disease. Neuropeptides 32:119-123
35. Arzt E, Pereda MP, Castro CP, Pagotto U, Renner U, Stalla GK 1999 Pathophysiological role of the cytokine network in the anterior pituitary gland. Front Neuroendocrinol 20:71-95
36. Sauer J, Arzt E, Gumprecht H, Hopfner U, Stalla GK 1994 Expression of interleukin-1 receptor antagonist in human pituitary adenomas in vitro. J Clin Endocrinol Metab 79:1857-1863
37. Gabay C, Dreyer M, Pellegrinelli N, Chicheportiche R, Meier CA 2001 Leptin directly induces the secretion of interleukin 1 receptor antagonist in human monocytes. J Clin Endocrinol Metab 86:783-791