Interleukin 1 and tumor necrosis factor in obese alcoholics compared with normal-weight patients

American Journal of Clinical Nutrition

Volumn 63, Issue 3, 1996, Pages 373-376

  Bunout, Daniel ^a,b   Muñoz, Carlos ^a   López, Marcelo ^a   De La Maza, María Pía ^a   Schlesinger, Liana ^a   Hirsch, Sandra ^a   Pettermann, Margarita ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

alcoholic liver disease; alcoholism; Obesity

Indexed keywords

INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALCOHOL LIVER DISEASE; ALCOHOLISM; ARTICLE; BODY FAT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; LIVER BIOPSY; LIVER CIRRHOSIS; MALE; OBESITY; SKINFOLD THICKNESS;

EID: 0029983063     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/63.3.373     Document Type: Article

References (24)

1. Bunout D, Gattas V, Iturriaga H, Perez C, Pereda T, Ugarte G. Nutritional status of alcoholic patients: its possible relationship to alcoholic liver damage. Am J Clin Nutr 1983;38:469-73.
2. Iturriaga H, Bunout D, Hirsch S, Ugarte G. Overweight as a risk factor or a predictive sign of histological liver damage in alcoholics. Am J Clin Nutr 1988;47:235-8.
3. Klain J, Fraser D, Goldstein J, et al. Liver histology abnormalities in the morbidly obese. Hepatology 1989;10:873-6.
4. Andus T, Bauer J, Gerok W. Effects of cytokines on the liver. Hepatology 1991;13:364-75.
5. Tilg H, Wilmer A, Vogel W, et al. Serum levels of cytokines in chronic liver diseases. Gastroenterology 1992;103:264-74.
6. Deviere J, Content J, Denys C, et al. Excessive in vitro bacterial lipopolysaccharide-induced production of monokines in cirrhosis. Hepatology 1990;11:628-34.
7. D'Souza NB, Bagby CJ, Nelson S, Lang CH, Spitzer JJ. Acute alcohol infusion suppresses endotoxin-induced serum tumor necrosis factor. Alcohol Clin Exp Res 1991;13:295-8.
8. Bjarnason I, Ward K, Peters TJ. The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet 1984;1:179-82.
9. Lohman TG, Roche AF, Martorel E, eds. Anthropometric standardization reference manual. Champaign, IL: Human Kinetics, 1988.
10. Durnin JVGA, Womersley J. Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 1974;32:77-94.
11. Baptista A, Bianchi L, DeGroote J, et al. Alcoholic liver disease: morphologic manifestations. Lancet 1981;1:707-11.
12. Cannon JG, Van der Meer JWM, Kwiatkowwski D, et al. Interleukin-1 in human plasma: optimization of blood collection, plasma extraction and radioimmunoassay methods. Lymphokine Res 1988;7:457-67
13. Bianchi L. Hepatic histology. Semin Liver Dis 1986;6:173-276.
14. Lieber CS. Metabolic effects of ethanol and its interaction with other drugs, hepatotoxic agents, vitamins and carcinogens. A 1988 update. Semin Liver Dis 1988;8:47-68.
15. Israel Y, Orrego H, Niemela O. Immune responses to alcohol metabolites: pathogenic and diagnostic implications. Semin Liver Dis 1988;8:81-90.
16. Hill DB, Marsano LS, McClain C. Increased plasma interleukin-8 concentrations in alcoholic hepatitis. Hepatology 1993;18:576-80.
17. Matsuoka M, Pham NT, Tsukamoto H. Differential effects of interleukin-1α, tumor necrosis factor α and transforming growth factor β1 on cell proliferation and collagen formation by cultured fat storing cells. Liver 1989;9:71-8.
18. Shiratory Y, Takada H, Hikiba Y, et al. Production of chemotactic factor, interleukin-8, from hepatocytes exposed to ethanol. Hepatology 1993;18:1477-82.
19. Roh MS, Moldawer LL, Ekman LG, et al. Stimulatory effect of interleukin-1 on hepatic metabolism. Metabolism 1986;35-419-24.
20. Busetto L, Baggio MB, Zurlo F, Carraro R, Digito M, Enzi G. Assessment of abdominal fat distribution in obese patients: anthropometry versus computerized tomography. 1992;16:731-6.
21. Endres S, Ghorbani R, Kelly V, et al. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med 1989;320:265-71.
22. McClain CJ, Cohen DA. Increased tumor necrosis factor production by monocytes in alcoholic hepatids. Hepatology 1989;9:349-51.
23. Bird GLA, Sheron N, Goka AKJ, Alexander GJ, Williams RS. Increased plasma tumor necrosis factor in severe alcoholic hepatitis. Ann Intern Med 1990;112.917-20.
24. Felver ME, Mezey E, McGuire M, et al. Plasma tumor necrosis factor predicts decreased long-term survival in severe alcoholic hepatitis. Alcohol Clin Exp Res 1990;14:255-9.