Mode of inhibition of short-patch base excision repair by thymine glycol within clustered DNA lesions

Journal of Biological Chemistry

Volumn 278, Issue 11, 2003, Pages 9378-9381

  Budworth, Helen ^a,b   Dianov, Grigory L ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; GLYCOLS; IONIZING RADIATION;

LESIONS;

DNA;

2 DEOXYRIBOSE 5 PHOSPHATE LYASE; 5,6 DIHYDRO 5,6 DIHYDROXYTHYMINE; APURINIC ACID; CELL EXTRACT; DNA; DNA DIRECTED DNA POLYMERASE BETA; ENDONUCLEASE; LYASE; PHOSPHATE; THYMINE DERIVATIVE; UNCLASSIFIED DRUG; 2 DEOXYRIBOSE 5 PHOSPHATE; 2-DEOXYRIBOSE 5-PHOSPHATE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DRUG DERIVATIVE; OLIGONUCLEOTIDE; OSMIUM TETRAOXIDE; RIBOSE PHOSPHATE; THYMINE;

APYRIMIDINIC SITE; ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE; EXCISION REPAIR; HUMAN; HUMAN CELL; IONIZING RADIATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; CHEMISTRY; DOSE RESPONSE; HELA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; TIME;

CARBON-OXYGEN LYASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; DNA DAMAGE; DNA POLYMERASE BETA; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; OLIGONUCLEOTIDES; OSMIUM TETROXIDE; RIBOSEMONOPHOSPHATES; THYMINE; TIME FACTORS;

EID: 0038322044     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212068200     Document Type: Article

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