-
1
-
-
0035948588
-
Identification and comparative analysis of a second runx3 promoter
-
Rini D., Calabi F. Identification and comparative analysis of a second runx3 promoter. Gene. 273:2001;13-22.
-
(2001)
Gene
, vol.273
, pp. 13-22
-
-
Rini, D.1
Calabi, F.2
-
2
-
-
0029918597
-
Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
-
Wang Q., Stacy T., Binder M., Marin-Padilla M., Sharpe A.H., Speck N.A. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc. Natl. Acad. Sci. USA. 93:1996;3444-3449.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3444-3449
-
-
Wang, Q.1
Stacy, T.2
Binder, M.3
Marin-Padilla, M.4
Sharpe, A.H.5
Speck, N.A.6
-
3
-
-
0030061554
-
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
-
Okuda T., van Deursen J., Hiebert S.W., Grosveld G., Downing J.R. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell. 84:1996;321-330.
-
(1996)
Cell
, vol.84
, pp. 321-330
-
-
Okuda, T.1
Van Deursen, J.2
Hiebert, S.W.3
Grosveld, G.4
Downing, J.R.5
-
4
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
[see comments]
-
Otto F., et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell. 89:1997;765-771. [see comments].
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
-
5
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
[see comments]
-
Komori T., et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 89:1997;755-764. [see comments].
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
-
6
-
-
18344389720
-
Causal relationship between the loss of RUNX3 expression and gastric cancer
-
Li Q.L., et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell. 109:2002;113-124.
-
(2002)
Cell
, vol.109
, pp. 113-124
-
-
Li, Q.L.1
-
7
-
-
18444406568
-
The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons
-
Levanon D., et al. The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons. EMBO J. 21:2002;3454-3463.
-
(2002)
EMBO J.
, vol.21
, pp. 3454-3463
-
-
Levanon, D.1
-
8
-
-
0027256023
-
Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor
-
Wang S., Wang Q., Crute B.E., Melnikova I.N., Keller S.R., Speck N.A. Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor. Mol. Cell. Biol. 13:1993;3324-3339.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 3324-3339
-
-
Wang, S.1
Wang, Q.2
Crute, B.E.3
Melnikova, I.N.4
Keller, S.R.5
Speck, N.A.6
-
9
-
-
0027184229
-
Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha
-
Ogawa E., et al. Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha. Virology. 194:1993;314-331.
-
(1993)
Virology
, vol.194
, pp. 314-331
-
-
Ogawa, E.1
-
10
-
-
0029973591
-
Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta
-
Sasaki K., et al. Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta. Proc. Natl. Acad. Sci. USA. 93:1996;12359-12363.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12359-12363
-
-
Sasaki, K.1
-
11
-
-
0030588487
-
The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo
-
Wang Q., et al. The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. Cell. 87:1996;697-708.
-
(1996)
Cell
, vol.87
, pp. 697-708
-
-
Wang, Q.1
-
12
-
-
0025746321
-
T(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1
-
Miyoshi H., Shimizu K., Kozu T., Maseki N., Kaneko Y., Ohki M. t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. Proc. Natl. Acad. Sci. USA. 88:1991;10431-10434.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10431-10434
-
-
Miyoshi, H.1
Shimizu, K.2
Kozu, T.3
Maseki, N.4
Kaneko, Y.5
Ohki, M.6
-
13
-
-
0026757174
-
Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt
-
Erickson P., et al. Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt. Blood. 80:1992;1825-1831.
-
(1992)
Blood
, vol.80
, pp. 1825-1831
-
-
Erickson, P.1
-
14
-
-
0026496547
-
Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells
-
Nisson P.E., Watkins P.C., Sacchi N. Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells. Cancer Genet. Cytogenet. 63:1992;81-88.
-
(1992)
Cancer Genet. Cytogenet.
, vol.63
, pp. 81-88
-
-
Nisson, P.E.1
Watkins, P.C.2
Sacchi, N.3
-
15
-
-
0029045087
-
The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion
-
Romana S.P., et al. The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion. Blood. 85:1995;3662-3670.
-
(1995)
Blood
, vol.85
, pp. 3662-3670
-
-
Romana, S.P.1
-
16
-
-
0031025416
-
Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene
-
Yergeau D.A., et al. Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene. Natl. Genet. 15:1997;303-306.
-
(1997)
Natl. Genet.
, vol.15
, pp. 303-306
-
-
Yergeau, D.A.1
-
17
-
-
0032079424
-
Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors
-
Okuda T., et al. Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors. Blood. 91:1998;3134-3143.
-
(1998)
Blood
, vol.91
, pp. 3134-3143
-
-
Okuda, T.1
-
18
-
-
0032830638
-
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
-
[see comments]
-
Song W.J., et al. Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat. Genet. 23:1999;166-175. [see comments].
-
(1999)
Nat. Genet.
, vol.23
, pp. 166-175
-
-
Song, W.J.1
-
19
-
-
0033559746
-
Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias
-
Osato M., et al. Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias. Blood. 93:1999;1817-1824.
-
(1999)
Blood
, vol.93
, pp. 1817-1824
-
-
Osato, M.1
-
20
-
-
0034667690
-
High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21
-
Preudhomme C., et al. High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21. Blood. 96:2000;2862-2869.
-
(2000)
Blood
, vol.96
, pp. 2862-2869
-
-
Preudhomme, C.1
-
21
-
-
0029892554
-
Retroviral insertional mutagenesis as a strategy to identify cancer genes
-
Jonkers J., Berns A. Retroviral insertional mutagenesis as a strategy to identify cancer genes. Biochim. Biophys. Acta. 1287:1996;29-57.
-
(1996)
Biochim. Biophys. Acta
, vol.1287
, pp. 29-57
-
-
Jonkers, J.1
Berns, A.2
-
22
-
-
0030052663
-
Til-1: A novel proviral insertion locus for Moloney murine leukaemia virus in lymphomas of CD2-myc transgenic mice
-
Stewart M., Terry A., O'Hara M., Cameron E., Onions D., Neil J.C. til-1 a novel proviral insertion locus for Moloney murine leukaemia virus in lymphomas of CD2-myc transgenic mice . J. Gen. Virol. 77:(Pt. 3):1996;443-446.
-
(1996)
J. Gen. Virol.
, vol.77
, Issue.PART 3
, pp. 443-446
-
-
Stewart, M.1
Terry, A.2
O'Hara, M.3
Cameron, E.4
Onions, D.5
Neil, J.C.6
-
23
-
-
0030741019
-
Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): Evidence for a new myc collaborating oncogene
-
Stewart M., et al. Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1) evidence for a new myc collaborating oncogene . Proc. Natl. Acad. Sci. USA. 94:1997;8646-8651.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8646-8651
-
-
Stewart, M.1
-
24
-
-
0023134626
-
Dsi-1, a region with frequent proviral insertions in Moloney murine leukemia virus-induced rat thymomas
-
Vijaya S., Steffen D.L., Kozak C., Robinson H.L. Dsi-1, a region with frequent proviral insertions in Moloney murine leukemia virus-induced rat thymomas. J. Virol. 61:1987;1164-1170.
-
(1987)
J. Virol.
, vol.61
, pp. 1164-1170
-
-
Vijaya, S.1
Steffen, D.L.2
Kozak, C.3
Robinson, H.L.4
-
25
-
-
0036223379
-
The common retroviral insertion locus Dsil maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 gene
-
Stewart M., Mackay N., Cameron E.R., Neil J.C. The common retroviral insertion locus Dsil maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 gene. J. Virol. 76:2002;4364-4369.
-
(2002)
J. Virol.
, vol.76
, pp. 4364-4369
-
-
Stewart, M.1
Mackay, N.2
Cameron, E.R.3
Neil, J.C.4
-
26
-
-
0032726951
-
Leukaemia disease genes: Large-scale cloning and pathway predictions
-
Li J., et al. Leukaemia disease genes large-scale cloning and pathway predictions . Nat. Genet. 23:1999;348-353.
-
(1999)
Nat. Genet.
, vol.23
, pp. 348-353
-
-
Li, J.1
-
27
-
-
0034021379
-
Transcription-coupled translation control of AML1/RUNX1 is mediated by cap- and internal ribosome entry site-dependent mechanisms
-
Pozner A., et al. Transcription-coupled translation control of AML1/RUNX1 is mediated by cap- and internal ribosome entry site-dependent mechanisms. Mol. Cell. Biol. 20:2000;2297-2307.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2297-2307
-
-
Pozner, A.1
-
28
-
-
0034090392
-
AML1 gene amplification: A novel finding in childhood acute lymphoblastic leukemia
-
Niini T., Kanerva J., Vettenranta K., Saarinen-Pihkala U.M., Knuutila S. AML1 gene amplification a novel finding in childhood acute lymphoblastic leukemia . Haematologica. 85:2000;362-366.
-
(2000)
Haematologica
, vol.85
, pp. 362-366
-
-
Niini, T.1
Kanerva, J.2
Vettenranta, K.3
Saarinen-Pihkala, U.M.4
Knuutila, S.5
-
29
-
-
0034745477
-
Amplification of AML1 in childhood acute lymphoblastic leukemias
-
Dal Cin P., et al. Amplification of AML1 in childhood acute lymphoblastic leukemias. Genes Chromosomes Cancer. 30:2001;407-409.
-
(2001)
Genes Chromosomes Cancer
, vol.30
, pp. 407-409
-
-
Dal Cin, P.1
-
30
-
-
85014143894
-
AML1 gene over-expression in childhood acute lymphoblastic leukemia
-
Mikhail F.M., et al. AML1 gene over-expression in childhood acute lymphoblastic leukemia. Leukemia. 16:2002;658-668.
-
(2002)
Leukemia
, vol.16
, pp. 658-668
-
-
Mikhail, F.M.1
-
31
-
-
0034792024
-
Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia
-
Busson-Le Coniat M., Khac F.N., Daniel M.T., Bernard O.A., Berger R. Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia. Genes Chromosomes Cancer. 32:2001;244-249.
-
(2001)
Genes Chromosomes Cancer
, vol.32
, pp. 244-249
-
-
Busson-Le Coniat, M.1
Khac, F.N.2
Daniel, M.T.3
Bernard, O.A.4
Berger, R.5
-
32
-
-
85014216614
-
Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation
-
Penther D., et al. Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation. Leukemia. 16:2002;1131-1134.
-
(2002)
Leukemia
, vol.16
, pp. 1131-1134
-
-
Penther, D.1
-
33
-
-
0034854751
-
Characterization of additional genetic events in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion: A molecular cytogenetics study
-
Ma S.K., et al. Characterization of additional genetic events in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion a molecular cytogenetics study . Leukemia. 15:2001;1442-1447.
-
(2001)
Leukemia
, vol.15
, pp. 1442-1447
-
-
Ma, S.K.1
-
34
-
-
0035659899
-
Fluorescence in situ hybridization study of TEL/AML1 fusion and other abnormalities involving TEL and AML1 genes. Correlation with cytogenetic findings and prognostic value in children with acute lymphocytic leukemia
-
Martinez-Ramirez A., et al. Fluorescence in situ hybridization study of TEL/AML1 fusion and other abnormalities involving TEL and AML1 genes. Correlation with cytogenetic findings and prognostic value in children with acute lymphocytic leukemia. Haematologica. 86:2001;1245-1253.
-
(2001)
Haematologica
, vol.86
, pp. 1245-1253
-
-
Martinez-Ramirez, A.1
-
35
-
-
0035141787
-
Amplification of the AML1 (CBFA2) gene on ring chromosomes in a patient with acute myeloid leukemia and a constitutional ring chromosome 21
-
Streubel B., Valent P., Lechner K., Fonatsch C. Amplification of the AML1 (CBFA2) gene on ring chromosomes in a patient with acute myeloid leukemia and a constitutional ring chromosome 21. Cancer Genet. Cytogenet. 124:2001;42-46.
-
(2001)
Cancer Genet. Cytogenet.
, vol.124
, pp. 42-46
-
-
Streubel, B.1
Valent, P.2
Lechner, K.3
Fonatsch, C.4
-
36
-
-
0037105587
-
Enforced expression of Runx2 perturbs T cell development at a stage coincident with β-selection
-
Vaillant F. Enforced expression of Runx2 perturbs T cell development at a stage coincident with β-selection. J. Immunol. 169:2002;2866-2874.
-
(2002)
J. Immunol.
, vol.169
, pp. 2866-2874
-
-
Vaillant, F.1
-
37
-
-
0033604455
-
A full-length Cbfal gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc
-
Vaillant F., et al. A full-length Cbfal gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc. Oncogene. 18:1999;7124-7134.
-
(1999)
Oncogene
, vol.18
, pp. 7124-7134
-
-
Vaillant, F.1
-
38
-
-
0035905751
-
Runx2: A novel oncogenic effector revealed by in vivo complementation and retroviral tagging
-
Blyth K., et al. Runx2 a novel oncogenic effector revealed by in vivo complementation and retroviral tagging . Oncogene. 20:2001;295-302.
-
(2001)
Oncogene
, vol.20
, pp. 295-302
-
-
Blyth, K.1
-
39
-
-
0030015294
-
Transcriptional activation of a retrovirus enhancer by CBF (AML1) requires a second factor: Evidence for cooperativity with c-Myb
-
Zaiman A.L., Lenz J. Transcriptional activation of a retrovirus enhancer by CBF (AML1) requires a second factor evidence for cooperativity with c-Myb . J. Virol. 70:1996;5618-5629.
-
(1996)
J. Virol.
, vol.70
, pp. 5618-5629
-
-
Zaiman, A.L.1
Lenz, J.2
-
40
-
-
0030794281
-
Core binding factor cannot synergistically activate the myeloperoxidase proximal enhancer in immature myeloid cells without c-Myb
-
Britos-Bray M., Friedman A.D. Core binding factor cannot synergistically activate the myeloperoxidase proximal enhancer in immature myeloid cells without c-Myb. Mol. Cell. Biol. 17:1997;5127-5135.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5127-5135
-
-
Britos-Bray, M.1
Friedman, A.D.2
-
41
-
-
0030070419
-
Overexpression of the AML1 proto-oncoprotein in NIH3T3 cells leads to neoplastic transformation depending on the DNA-binding and transactivational potencies
-
Kurokawa M., et al. Overexpression of the AML1 proto-oncoprotein in NIH3T3 cells leads to neoplastic transformation depending on the DNA-binding and transactivational potencies. Oncogene. 12:1996;883-892.
-
(1996)
Oncogene
, vol.12
, pp. 883-892
-
-
Kurokawa, M.1
-
42
-
-
9844239378
-
CBF beta-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells
-
Cao W., et al. CBF beta-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells. Oncogene. 15:1997;1315-1327.
-
(1997)
Oncogene
, vol.15
, pp. 1315-1327
-
-
Cao, W.1
-
43
-
-
0034682252
-
Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - A model for overcoming inhibition of proliferation by CBF oncoproteins
-
Lou J., Cao W., Bernardin F., Ayyanathan K., Rauscher F.J. III, Friedman A.D. Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins. Oncogene. 19:2000;2695-2703.
-
(2000)
Oncogene
, vol.19
, pp. 2695-2703
-
-
Lou, J.1
Cao, W.2
Bernardin, F.3
Ayyanathan, K.4
Rauscher F.J. III5
Friedman, A.D.6
-
44
-
-
0034603080
-
Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle
-
Strom D.K., et al. Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle. J. Biol. Chem. 275:2000;3438-3445.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3438-3445
-
-
Strom, D.K.1
-
45
-
-
85047696566
-
AML1 stimulates G1 to S progression via its transactivation domain
-
Bernardin F., Friedman A.D. AML1 stimulates G1 to S progression via its transactivation domain. Oncogene. 21:2002;3247-3252.
-
(2002)
Oncogene
, vol.21
, pp. 3247-3252
-
-
Bernardin, F.1
Friedman, A.D.2
-
46
-
-
14444287506
-
Overexpression of AML1 renders a T hybridoma resistant to T cell receptor-mediated apoptosis
-
Fujii M., et al. Overexpression of AML1 renders a T hybridoma resistant to T cell receptor-mediated apoptosis. Oncogene. 17:1998;1813-1820.
-
(1998)
Oncogene
, vol.17
, pp. 1813-1820
-
-
Fujii, M.1
-
47
-
-
0025200110
-
T-cell differentiation in thymus organ cultures
-
Jenkinson E.J., Owen J.J. T-cell differentiation in thymus organ cultures. Semin. Immunol. 2:1990;51-58.
-
(1990)
Semin. Immunol.
, vol.2
, pp. 51-58
-
-
Jenkinson, E.J.1
Owen, J.J.2
|