Autoimmune thyroid diseases: Etiology, pathogenesis, and dermatologic manifestations

Journal of the American Academy of Dermatology

Volumn 48, Issue 5, 2003, Pages 641-662

  Ai, Julia ^a   Leonhardt, Janie M ^a   Heymann, Warren R ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; AUTOANTIBODY;

APOPTOSIS; AUTOIMMUNE DISEASE; CLINICAL FEATURE; ENVIRONMENTAL FACTOR; GENETIC SUSCEPTIBILITY; GRAVES DISEASE; HASHIMOTO DISEASE; HEREDITY; HUMAN; HYPOTHYROIDISM; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SKIN MANIFESTATION; THYROID DISEASE;

EID: 0038284750     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1067/mjd.2003.257     Document Type: Article

References (128)

1. Weetman AP. Autoimmunity and endocrinology. Exp Clin Endocrinol Diabetes 1999;107(Suppl):S63-6.
2. Heward J, Gough SCL. Genetic susceptibility to the development of autoimmune disease. Clin Sci (Colch) 1997;93:479-91.
3. Barbesino G, Tomer Y, Concepcion E, Davis TF, Greenberg DA, the International Consortium for the Genetics of Autoimmune Thyroid Disease. Linkage analysis of candidate genes and autoimmune thyroid disease: I, selected immunoregulatory genes. J Clin Endocrinol Metab 1998;83:1580-4.
4. Allahabadia A, Gough SCL. The different approaches to the genetic analysis of autoimmune thyroid disease. J Endocrinol 1999;163:7-13.
5. Weetman AP. Determinants of autoimmune thyroid disease. Nat Immun 2001;2:769-70.
6. Chistyakov DA, Savost'anov KV, Turakulov RI, Nosikov VV. Genetic determinants of Graves disease. Mol Genet Metab 2000;71:66-9.
7. Philippou G, Krimitzas A, Kaltsas G, Anastasiou E, Souvatzoglou A, Alevizaki M. HLA DQA1*0501 and DRB1*0301 antigens do not independently convey susceptibility to Graves' disease. J Endocrinol Invest 2001;24:88-91.
8. Barbesino G, Tomer Y, Concepcion E, Davis TF, Greenberg DA, the International Consortium for the Genetics of Autoimmune Thyroid Disease. Linkage analysis of candidate genes and autoimmune thyroid disease: II, selected gender-related genes and the X-chromosome. J Clin Endocrinol Metab 1998;83:3290-5.
9. Elsheikh M, Wass JA, Conway GS. Autoimmune thyroid syndrome in women with Turner's syndrome-the association with karyotype. Clin Endocrinol (Oxf) 2001;55:223-6.
10. Karlsson B, Gustafsson J, Hedov G, Ivarsson S-A, Anneren G. Thyroid dysfunction in Down's syndrome: relation to age and thyroid autoimmunity. Arch Dis Child 1998;79:242-5.
11. Nicholson LB, Wong FS, Ewins DL, Butler J, Holland A, Demaine AG, et al. Susceptibility to autoimmune thyroiditis in Down's syndrome is associated with the major histocompatibility class II DQA 0301 allele. Clin Endocrinol (Oxf) 1994;41:381-3.
12. Bucci I, Napolitano G, Guiliani C, Llo S, Minnucci A, DiGiacomo F, et al. Zinc sulfate supplementation improves thyroid function in hypozeincemic Down children. Biol Trace Elem Res 1999;67:257-68.
13. Kanavin OJ, Aaseth J, Birketvedt GS. Thyroid hypofunction in Down's syndrome: is it related to oxidative stress? Biol Trace Elem Res 2000;78:35-42.
14. Mountz JD, Zhang HG, Hsu HC, Fleck M, Wu J, Al-Maini MH, et al. Apoptosis and cell death in the endocrine system. Recent Prog Horm Res 1999;54:235-68.
15. McIver B, Morris JC. The pathogenesis of Graves' disease. Endocrinol Metab Clin North Am 1998;27:73-89.
16. Kraemer MH, Donadi EA, Tambascia MA, Magna LA, Prigenzi LS. Relationship between HLA antigens and infectious agents in contributing towards the development of Graves' disease. Immunol Invest 1998;27:17-29.
17. Fatourechi V. Demystifying autoimmune thyroid disease. Postgrad Med 2000;107:127-34.
18. Saravanan P, Dayan CM. Thyroid autoantibodies. Endocrinol Metab Clin North Am 2001;30:315-37.
19. Heufelder AE, Joba W, Morganethaler NG. Autoimmunity involving the human sodium/iodide symporter: fact or fiction? Exp Clin Endocrinol Diabetes 2001;109:35-40.
20. Fenton CL, Patel A, Tuttle RM, Francis GL. Autoantibodies to p53 in sera of patients with autoimmune thyroid disease. Ann Clin Lab Sci 2000;30:179-83.
21. Kiljanski JI, Peele K, Stachura I, Pickeral J, Stolarski C, Kennerdell JS, et al. Antibodies against striated muscle, connective tissue and nuclear antigens in patients with thyroid-associated ophthalmopathy: should Graves' disease be considered a collagen disorder? J Endocrinol Invest 1997;20:585-91.
22. Osundeko O, Hasinski S, Rose LI. Anticardiolipin antibodies in Hashimoto's disease. Endocr Pract 2001;7:181-3.
23. Nabriski D, Ellis M, Ness-Abramof R, Shapiro M, Shenkman L. Autoimmune thyroid disease and antiphospholipid antibodies. Am J Hematol 2000;64:73-5.
24. Jasani B, Ternynck T, Lazarus JH, Phillips DIW, Avrameas S, Parkes AB. Natural autoantibody status in patients with Hashimoto's thyroiditis. J Clin Lab Immunol 1999;51:9-20.
25. Ara J, Robert J, Mirapeix E, Botey A, Darnell A. High prevalence of antithyroid antibodies in anti-glomerular basement membrane antibody-mediated disease. J Nephrol 2000;13:65-7.
26. Appetecchia M, Castelli M, Delpino A. Anti-heat shock protein autoantibodies in autoimmune thyroiditis: preliminary study. J Exp Clin Cancer Res 1997;16:395-400.
27. Nishino M, Yabe S, Murakami M, Kanda T, Kobayashi I. Detection of antipituitary antibodies in patients with autoimmune thyroid disease. Endocr J 2001;48:185-91.
28. Borgerson K, Bretz J, Baker J Jr. The role of Fas-mediated apoptosis in thyroid autoimmune disease. Autoimmunity 1999;30:251-64.
29. Eguchi K. Apoptosis in autoimmune diseases. Intern Med 2001;40:275-84.
30. Phelps E, Wu P, Bretz J, Baker JR. Autoimmune thyroid disease. Endocrinol Metab Clin North Am 2000;29:375-88.
31. Stassi G, Zeuner A, Di Liberto D, Todaro M, Ricci-Vitiani L, De Maria R. Fas-FasL in Hashimoto's thyroiditis. J Clin Immunol 2001;21:19-23.
32. Palazzo FF, Hammond LJ, Goode AW, Mirakian R. Death of the autoimmune thyrocyte: is it pushed or does it jump? Thyroid 2000;10:561-72.
33. Andrikoula M, Tsatsoulis A. The role of Fas-mediated apoptosis in thyroid disease. Eur J Endocrinol 2001;144:561-8.
34. Arscott PL, Baker J Jr. Apoptosis and thyroiditis. Clin Immunol Immunopathol 1998;87:207-17.
35. Evangelopoulou ME, Alevizaki M, Toumanidis S, Piperingos G, Mavrikakis M, Sotou D, et al. Mitral valve prolapse in autoimmune thyroid disease: an index of systemic autoimmunity? Thyroid 1999;9:973-7.
36. Goh KL, Wang F. Thyroid disorders in systemic lupus erythematosus. Ann Rheum Dis 1986;45:579-83.
37. Nicholson D, White S, Lipson A, Jacobs RP, Borenstein DG. Progressive systemic sclerosis and Graves' disease: report of three cases. Arch Intern Med 1986;146:2350-2.
38. DeKeyser L, Narhi DC, Furst DE, Huberman AK, Ross R, Clements J, et al. Thyroid dysfunction in a prospectively followed series of patients with progressive systemic sclerosis. J Endocrinol Invest 1990;13:161-9.
39. Gordon MB, Klein I, Dekker A, Rodnan GP, Medsger TA Jr. Thyroid disease in progressive systemic sclerosis: increased frequency of glandular fibrosis and hypothyroidism. Ann Intern Med 1981;81:260-3.
40. Jonsson H, Nived O, Sturfelt D. Thyroid disorders in systemic lupus erythematosus are associated with secondary Sjögren's syndrome. Ann Rheum Dis 1987;46:349-52.
41. Danieli MG, Rossetti L, Fraticelli P, Malcangi G, Testa I, Danieli G. Autoimmune thyroid diseases in patients with undifferentiated connective tissue disease. Clin Rheumatol 2000;19:42-6.
42. Callen JP, McCall MW. Bullous pemphigoid and Hashimoto's thyroiditis. J Am Acad Dermatol 1981;5:558-60.
43. How J, Bewsher PD, Stankler L. Bullous pemphigoid, polymyalgia rheumatica, and thyroid disease. Br J Dermatol 1980;103:201-4.
44. Cunningham MJ, Zone JJ. Thyroid abnormalities in dermatitis herpetiformis: prevalence of clinical thyroid disease and thyroid autoantibodies. Ann Intern Med 1985;102:194-6.
45. Wolf R, Feuerman EJ. Pemphigus in association with autoimmune thyroid disease. Cutis 1981;27:423-4.
46. Niepomniszcze H, Amad RH. Skin disorders and thyroid diseases. J Endocrinol Invest 2001;24:628-38.
47. Leznoff A, Sussman GL. Syndrome of idiopathic chronic urticaria and angioedema with thyroid autoimmunity: a study of 90 patients. J Allergy Clin Immunol 1989;84:66-71.
48. Bloch MH, Sowers JR. Vitiligo and polyglandular autoimmune endocrinopathy. Cutis 1985;36:417-9.
49. Colao A, Pivonella R, Faggiano A, Filippella M, Ferone D, Di-Somma C, et al. Increased prevalence of thyroid autoimmunity in patients successfully treated for Cushing's disease. Clin Endocrinol (Oxf) 2000;53:13-9.
50. Park YS, Kim TW, Kim WB, Cho BY. Increased prevalence of autoimmune thyroid disease in patients with type I diabetes. Korean J Intern Med 2000;15:202-10.
51. Centanni M, Marignani M, Gargano L, Corleto VD, Casini A, Delle Fave G, et al. Atrophic body gastritis in patients with autoimmune thyroid disease: an underdiagnosed association. Arch Intern Med 1999;159:1726-30.
52. Cordiano I, Betterle C, Spadaccino CA, Soini B, Girolami A, Fabris F. Autoimmune thrombocytopenia (AITP) and thyroid autoimmune disease (TAD): overlapping syndromes? Clin Exp Immunol 1998;113:373-8.
53. Modugno GC, Pirodda A, Ferri GC, Montana T, Rasciti L, Ceroni AR. A relationship between autoimmune thyroiditis and benign paroxysmal positional vertigo. Med Hypotheses 2000;54:614-5.
54. Shagam JY. Thyroid disease: an overview. Radiol Technol 2001;73:25-40.
55. Heymann WR. Advances in the cutaneous manifestations of thyroid disease. Int J Dermatol 1997;36:641-5.
56. Lang PG Jr. Cutaneous manifestations of thyroid disease. Cutis 1978;21:862-6.
57. Alsanea O, Clark OH. The treatment of Graves' disease: the advantages of surgery. Endocrinol Metab Clin North Am 2000;29:321-37.
58. Donnelly A. Skin signs of systemic disease. Aust Fam Physician 1999;28:1217-22.
59. Heymann WR. Chronic urticaria and angioedema associated with thyroid autoimmunity: review and therapeutic implications. J Am Acad Dermatol 1999;40:229-32.
60. Stadlmayr W, Spitzweg C, Bichlmair AM, Heufelder AE. TSH receptor transcripts and TSH receptor-like immunoreactivity in orbital and pretibial fibroblasts of patients with Graves' ophthalmopathy and pretibial myxedema. Thyroid 1997;7:3-12.
61. Missner SC, Ramsay EW, Houck HE, Kauffman CL. Graves' disease presenting as localized myxedema in a thigh donor graft site. J Am Acad Dermatol 1998;39:846-9.
62. Fatourechi V, Pajouhi M, Fransway AF. Dermopathy of Graves disease (pretibial myxedema). Medicine (Baltimore) 1994;73:1-7.
63. Pingsmann A, Ockenfels HM, Patsalis TH. Surgical excision of pseudotumorous pretibial myxedema. Foot Ankle Int 1996;17:107-10.
64. Heymann WR. Cutaneous manifestations of thyroid disease. J Am Acad Dermatol 1992;26:885-902.
65. Pujol RM, Monmany J, Bague S, Alomar A. Graves' disease presenting as localized myxoedematous infiltration in a smallpox vaccination scar. Clin Exp Dermatol 2000;25:132-4.
66. Vanhoenacker FM, Pelckmans MC, De Beuckeleer LH, Colpaert CG, De Schepper AM. Thyroid acropachy: correlation of imaging and pathology. Eur Radiol 2001;11:1058-62.
67. Rapoport B, Alsabeh R, Aftergood D, McLachlan SM. Elephantiasic pretibial myxedema: insight into and a hypothesis regarding the pathogenesis of the extrathyroidal manifestations of Graves' disease. Thyroid 2000;10:685-92.
68. Cho S, Choi JH, Sung KJ, Moon KC, Koh JK. Graves' disease presenting as elephantiasic pretibial myxedema and nodules of the hands. Int J Dermatol 2001;40:276-7.
69. Shishido M, Kuroda K, Tsukifuji R, Fujita M, Shinkai H. A case of pretibial myxedema associated with Graves' disease: an immunohistochemical study of serum-derived hyaluronan-associated protein. J Dermatol 1995;22:948-52.
70. Chang TC, Kao SC, Huang KM. Octreotide and Graves' ophthalmopathy and pretibial myxedema. Br Med J 1992;304:158.
71. Wu SL, Chang TC, Chang TJ, Kuo YF, Hsaio YL, Chang CC. Cloning and sequencing of complete thyrotropin receptor transcripts in pretibial fibroblast culture cells. J Endocrinol Invest 1996;19:365-70.
72. Mullin GE, Eastern JS. Cutaneous signs of thyroid disease. Am Fam Physician 1986;34:93-8.
73. Diven DG, Gwinup G, Newton RC. The thyroid. Dermatol Clin 1989;7:547-57.
74. Seigel RS, Thrall JH, Sisson JJ. 99mTc-pyrophosphate scan and radiographic correlation in thyroid acropachy: case report. J Nucl Med 1976;17:791-3.
75. Torres-Reyes E, Staple TW. Roentgenographic appearance of thyroid acropachy. Clin Radiol 1970;25:95-100.
76. King LR, Braunstein H, Chambers D, Goldsmith R. A case study of peculiar soft-tissue and bony changes in association with thyroid disease. J Clin Endocrinol Metab 1959;19:1323-30.
77. Parker LN, Wu S-Y, Lai MK, Ramadan MB, Rajan RK, Yusi AM. The early diagnosis of atypical thyroid acropachy. Arch Intern Med 1982;142:1749-51.
78. Kato H, Uyeki Y, Kitajama Y, Yaoita H. A case of dermatomyositis and Hashimoto's thyroiditis. J Dermatol 1988;15:273-5.
79. Inoue K, Okajima T, Tanaka E, Ando B, Takeshita M, Masuda A, et al. A case of Graves' disease associated with autoimmune hepatitis and mixed connective tissue disease. Endocr J 1999;46:173-7.
80. Coll J, Anglada J, Tomas S, Reth P, Goday A, Millan M, et al. High prevalence of subclinical Sjogren's syndrome features in patients with autoimmune thyroid disease. J Rheumatol 1997;24:1719-24.
81. Hodak E, Shamai-Lubovitz O, David M, Hazaz B, Katzenelson-Weissman V, Lahav M, et al. Immunologic abnormalities associated with primary anetoderma. Arch Dermatol 1992;128:799-803.
82. Reunala T, Collin P. Diseases associated with dermatitis herpetiformis. Br J Dermatol 1997;136:315-8.
83. Gambichler T, Linhart C, Wolter M. Mid-dermal elastolysis associated with Hashimoto's thyroiditis. J Eur Acad Dermatol Venereol 1999;12:245-9.
84. Holmes RC, Black MM. Herpes gestationis. J Am Acad Dermatol 1980;3:474-7.
85. Nakatsui T, Lin AN. Onycholysis and thyroid disease: report of three cases. J Cutan Med Surg 1998;3:40-2.
86. Bartalena L, Bogazzi F, Chiovato L, Tanda ML, Martino E. Graves' hyperthyroidism and ophthalmopathy associated with pemphigus vulgaris: onset of thyroid autoimmune disease during chronic low-dose glucocorticoid therapy. J Endocrinol Invest 1997;20:155-7.
87. Nakamura S, Nakayaa K, Imai T, Ihara C, Ootani A. Sweet's syndrome in a patient with Basedow's disease. J Dermatol 1988;15:451-3.
88. Kumar V, Rajadhyaksha M, Wortsman J. Celiac disease-associated autoimmune endocrinopathies. Clin Diagn Lab Immunol 2001;8:678-85.
89. Bonapace ES, Srinivasan R. Simultaneous occurrence of inflammatory bowel disease and thyroid disease. Am J Gastroenterol 2001;96:1925-6.
90. Jannsen HL, Smelt AH, van Hoek B. Graves' hyperthyroidism in a patient with primary sclerosing cholangitis: coincidence or combined pathogenesis? Eur J Gastroenterol Hepatol 1998;10:269-71.
91. Karni A, Abramsky O. Association of MS with thyroid disorders. Neurology 1999;53:883-5.
92. Marino M, Ricciardi R, Pinchera A, Barbesino G, Manetti L, Chiovato L, et al. Mild clinical expression of myasthenia gravis associated with autoimmune thyroid diseases. J Clin Endocrinol Metab 1997;82:438-43.
93. Ohtsuka Y, Yamamoto K, Goto Y, Mizuta T, Ozaki I, Setoguchi Y, et al. Localized myxedema, associated with increased serum hyaluronic acid, and response to steroid pulse therapy. Intern Med 1995;34:424-9.
94. Uysal AR, Corapcioglu D, Tonyukuk VC, Gullu S, Sav H, Kamel N, et al. Effect of octreotide treatment on Graves' ophthalmopathy. Endocr J 1999;46:573-7.
95. Pasquali D, Vassallo P, Esposito D, Bonavolonta G, Bellastella A, Sinisi AA. Somatostatin receptor gene expression and inhibitory effects of octreotide on primary cultures of orbital fibroblasts from Graves' ophthalmopathy. J Mol Endocrinol 2000;25:63-71.
96. Antonelli A, Navarranne A, Palla R, Alberti B, Saracino A, Mestre C, et al. Pretibial myxedema and high-dose intravenous immunoglobulin treatment. Thyroid 1994;4:399-408.
97. Chang CC, Chang TC, Kao SC, Kuo YF, Chien LF. Pentoxifylline inhibits the proliferation and glycosaminoglycan synthesis of cultured fibroblasts derived from patients with Graves' ophthalmopathy and pretibial myxedema. Acta Endocrinol 1993;129:322-7.
98. Salvi M, De Chiara F, Gardini E, Minelli R, Bianconi L, Alinovi A, et al. Echographic diagnosis of pretibial myxedema in patients with autoimmune thyroid disease. Eur J Endocrinol 1994;131:113-9.
99. Solanki SV, Shah SS, Kothari UR. Thyroid acropachy. Indian J Med Sci 1973;27:708-10.
100. Nixon DW, Samols E. Acral changes associated with thyroid diseases. JAMA 1970;212:1175-81.
101. Slatosky J, Shipton B, Wahba H. Thyroiditis: differential diagnosis and management. Am Fam Physician 2000;61:1047-52, 1054.
102. De Kerdanet M, Lucas J, Lemee F, Lecornu M. Turner's syndrome with X-isochromosome and Hashimoto's disease. Clin Endocrinol (Oxf) 1994;41:673-6.
103. Takasu N, Yamada T, Takasu M, Komiya I, Nagasawa Y, Asawa T, et al. Disappearance of thyrotropin-blocking antibodies and spontaneous recovery from hypothyroidism in autoimmune thyroiditis. N Engl J Med 1992;326:513-8.
104. Zettinig G, Weissel M, Flores J, Dudczak R, Vogelsang H. Dermatitis herpetiformis is associated with atrophic but not goitrous variant of Hashimoto's thyroiditis. Eur J Clin Invest 2000;30:53-7.
105. Hierholzer K, Finke R. Myxedema. Kidney Int Suppl 1997;59:S82-9.
106. Heymann WR, Gans EH, Manders SM, Green JJ, Haimowitz JE. Xerosis in hypothyroidism: a potential role for the use of topical thyroid hormone in euthyroid patients. Med Hypotheses 2001;57:736-9.
107. Feingold KR, Elias PM. Endocrine-skin interactions. J Am Acad Dermatol 1987;17:921-40.
108. Frienkel RK, Frienkel N. Hair growth and alopecia in hypothyroidism. Arch Dermatol 1972;106:349-52.
109. Singh SK, Singh KK, Sahay RK. Images in medicine: Hashimoto's thyroiditis with orbitopathy and dermopathy. J Postgrad Med 2000;46:286-7.
110. Apaydin R, Bilen N, Bayramgurler D, Harova G, Cetinarslan B. Lichen amyloidosis, ankylosing spondylitis, and autoimmune thyroiditis: coincidence or association? J Eur Acad Dermatol Venereol 2000;14:135-7.
111. Nishimoto A, Tomiyoshi Y, Sakemi T, Kanegae F, Nakamura M, Ikeda Y, et al. Simultaneous occurrence of minimal change glomerular disease, sarcoidosis, and Hashimoto's thyroiditis. Am J Nephrol 2000;20:425-8.
112. Dix JH, Levy WJ, Fuenning C. Remission of acanthosis nigricans, hypertrichosis, and Hashimoto's thyroiditis with thyroxine replacement. Pediatr Dermatol 1986;3:323-6.
113. Milgraum SS, Mitchell AJ, Bacon GE, Rasmussen JE. Alopecia areata, endocrine function, and autoantibodies in patients 16 years of age or younger. J Am Acad Dermatol 1987;17:57-61.
114. Coleman R, Hays RJ. Chronic mucocutaneous candidiasis associated with hypothyroidism: a distinct syndrome? Br J Dermatol 1999;136:24-9.
115. Vazquez-Lopez F, Gonzalez-Lopez MA, Raya-Aguado C, Perez-Oliva N. Localized granuloma annulare and autoimmune thyroiditis: a new case report. J Am Acad Dermatol 2000;43:943-5.
116. Tremaine R, Adam JE, Orizaga M. Morphea coexisting with lichen sclerosus et atrophicus. Int J Dermatol 1990;29:486-9.
117. Lutfi RJ, Fridmanis M, Misiunas AL, Pafume O, Gonzalez EA, Villemur JA, et al. Association of melasma with thyroid autoimmunity and other thyroidal abnormalities and their relationship to the origin of the melasma. J Clin Endocrinol Metab 1985;61:28-31.
118. Rosen K, Lindstedt G, Mobacken H, Nystrom E. Thyroid function in patients with pustulosis palmoplantaris. J Am Acad Dermatol 1988;19:1009-16.
119. Velasco JA, Santos JC, Villabona V, Santana J. Reticular erythematous mucinosis and acral papulokeratotic lesions associated with myxedema due to Hashimoto thyroiditis. Dermatology 1992;184:73-7.
120. Perros P, Singh RK, Ludlam CA, Frier BM. Prevalence of pernicious anemia in patients with type I diabetes mellitus and autoimmune thyroid disease. Diabet Med 2000;17:749-51.
121. Shah SA, Peppercorn MA, Pallotta JA. Autoimmune (Hashimoto's) thyroiditis associated with Crohn's disease. J Clin Gastroenterol 1998;26:117-20.
122. Maclaren N, Chen QY, Kukreja A, Marker J, Chang CH, Sun ZS. Autoimmune hypogonadism as part of an autoimmune polyglandular syndrome. J Soc Gynecol Investig 2001;8:S52-4.
123. Gorlin R, Cohen M Jr, Condon L, Burke B. Bannayan-Riley-Ruvalcaba syndrome. Am J Med Genet 1992;44:307-14.
124. Polizzi A, Ruggieri M, Vecchio I, Genovese S, Rampello L, Raffaele R. Autoimmune thyroiditis and acquired demyelinating polyradiculoneuropathy. Clin Neurol Neurosurg 2001;103:151-4.
125. Selim M, Drachman DA. Ataxia associated with Hashimoto's disease: progressive non-familial adult onset cerebellar degeneration with autoimmune thyroiditis. J Neurol Neurosurg Psychiatry 2001;71:81-7.
126. Vitti P, Rago T, Barbesino G, Chiovato L. Thyroiditis: clinical aspects and diagnostic imaging. Rays 1999;24:301-14.
127. Guerra LN, Moiguer S, Karner M, de Molina MC, Sreider CM, Burdman JA. Antioxidants in the treatment of Graves' disease. IUBMB Life 2001;51:105-9.
128. Diez S, Banias H, Diez-Martin JL, Briz M, Estrado J, Barcelo B. Apparent cure of Graves-Basedow disease after sibling allogeneic bone marrow transplantation. Clin Endocrinol (Oxf) 1999;50:267-70.