Antibodies against striated muscle, connective tissue and nuclear antigens in patients with thyroid-associated ophthalmopathy: Should Graves' disease be considered a collagen disorder?

Journal of Endocrinological Investigation

Volumn 20, Issue 10, 1997, Pages 585-591

  Kiljanski, J I ^a   Peele, K ^b   Stachura, I ^b   Pickeral, J ^b   Stolarski, C ^c   Kennerdell, J S ^c   Wall, J R ^c,d  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^b ALLEGHENY GENERAL HOSPITAL   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d ALLEGHENY SINGER RESEARCH INSTITUTE   (United States)

Author keywords

Antinuclear antibodies; Graves' disease; Thyroid associated ophthalmopathy

Indexed keywords

AUTOANTIBODY; CELL NUCLEUS ANTIGEN; ENDOMYSIUM ANTIBODY; RIBONUCLEOPROTEIN ANTIBODY;

ADULT; AGED; ANTIBODY BLOOD LEVEL; ANTIGEN BINDING; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; COLLAGEN DISEASE; CONNECTIVE TISSUE; CONTROLLED STUDY; CYTOPLASM; DISEASE CLASSIFICATION; DISEASE DURATION; EXTRAOCULAR MUSCLE; EYE DISEASE; FEMALE; FLUORESCENCE; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; IMMUNOFLUORESCENCE; INFLAMMATION; INTERSTITIUM; MAJOR CLINICAL STUDY; MALE; MEMBRANE; SKELETAL MUSCLE; SWINE; THYROID GLAND;

EID: 0031455124     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03346914     Document Type: Article

References (46)

1. Burch H.B., Wartofsky L. Graves' ophthalmopathy: current concepts regarding pathogenesis and management. Endocr. Rev. 14: 747, 1993.
2. Kiljanskli J.I., Nebes V., Wall J.R. The ocular muscle cell is a target of the immune system in endocrine ophthalmopathy. Int. Arch. Allergy Immunol. 106: 204, 1995.
3. Toccafondi R., Rotella C. M., Zonferati R., Tanini A. Humoral factors in Graves' ophthalmopathy. In: Pinchera A., Ingbar S.H., McKenzie J.M., Fenzi G.F. (Eds), Thyroid Autoimmunity. Plenum Press, New York, 1987, p. 99.
4. Bahn R.S., Smith T.J., Gorman C.A. The central role of the fibroblast in the pathogenesis of extrathyroidal manifestations of Graves' disease. Acta Endocrinol. (Copenh.) 121: 75, 1989.
5. Bahn R.S., Gorman C.A., Johnson C.M., Smith T.J. Presence of antibodies in the sera of patients with Graves' disease recognizing a 23 kilodalton fibroblast protein. J. Clin. Endocrinol. Metab. 69: 622, 1989.
6. Bahn R.S., Heufelder A.E. Orbital connective tissue in endocrine ophthalmopathy. In: Kahaly G. (Ed.), Endocrine Ophthalmopathy. Molecular, Immunological and Clinical Aspects. Dev. Ophthalmol., Karger, Basel, 1993, p. 46.
7. Heufelder A.E., Bahn R. S. Elevated expression in situ of selectin and immunoglobulin superfamily type adhesion molecules in retroocular connective tissues from patients with Graves' ophthalmopathy. Clin. Exp. Immunol. 91: 381, 1993.
8. Wall J.R., Strakosch C.R., Fang S.L., Ingbar S.H., Braverman L.E. Thyroid binding antibodies and other immunological abnormalities in patients with Graves' ophthalmopathy: effect of treatment with cyclophosphamide. Clin. Endocrinol. 10: 79, 1979.
9. Wall J.R., Trewin A., Fang S. L., Ingbar S. H., Braverman L.E. Studies of immunoreactivity to human lacrimal gland fractions in patients with ophthalmic Graves' disease. J. Endocrinol. Invest. 1: 253, 1978.
10. McDermott M.T., West S.G., Emlen J.W., Kidd G.S. Antideoxyribonucleic acid antibodies in Graves' disease. J. Clin. Endocrinol. Metab. 71: 509, 1990.
11. Bartalena L., Martino E., Grasso L. Circulating antibodies to DNA-related antigens in patients with autoimmune thyroid disorders. Autoimmunity 14: 33, 1992.
12. Kapusta M., Salvi M., Triller H., Gardini E., Bernard N., Wall J.R. Eye muscle membrane reactive antibodies are not detected in serum or immunoglobulin fraction of patients with thyroid-associated ophthalmopathy using ELISA and crude membranes. Autoimmunity 7: 33, 1990.
13. Kodama K., Sikorska H., Bandy-Dafoe P., Bayly R., Wall J.R. Demonstration of circulating antibody against a soluble eye muscle antigen in Graves' ophthalmopathy. Lancet ii: 1353, 1982.
14. Atkinson S., Holcombe M., Kendall-Taylor P. Ophthalmopathic immunoglobulin in patients with Graves' ophthalmopathy. Lancet ii: 374, 1984.
15. Miller A., Sikorska H., Salvi M., Wall J.R. Evaluation of an enzyme-linked immunosorbent assay for the measurement of antibodies against eye muscle membrane antigens in Graves' ophthalmopathy. Acta Endocrinol. (Copenh.) 113: 514, 1986.
16. Salvi M., Miller A., Wall J.R. Human orbital tissue and thyroid membranes express a 64 kDa protein which is recognized by autoantibodies in the serum of patients with thyroid-associated ophthalmopathy. FEBS Lett. 232: 135, 1988.
17. Kendler D.L., Rootman J., Huber G. K., Davies T.F. A 64 kDa membrane antigen is a recurrent epitope for natural autoantibodies in patients with Graves' thyroid and ophthalmic diseases. Clin. Endocrinol. (Oxf.) 35: 539, 1991.
18. Hiromatsu Y., Sato M., Tanaka K., Shoji S., Nonaka K., Chinami M., Fukazawa H. Significance of anti-eye muscle antibody in patients with thyroid associated ophthalmopathy by quantitative Western blot. Autoimmunity 14: 18, 1993.
19. Wall J.R., Scalise D., Hayes M., Stolarski C., Nebes V., Kiljansk J., Salvi M., Sato Native gel electrophoresis and isoelectric focusing of a 64kilodalton eye muscle protein shows that it is an important target for serum autoantibodies in patients with thyroid-associated ophthalmopathy and not expressed in other skeletal muscle. J. Clin. Endocrinol. Metab. 80: 1226, 1995.
20. Faryna M., Nauman J., Gardas J. Measurements of autoantibodies against human eye muscle membranes in Graves' ophthalmopathy. Br. Med. J. 59: 104, 1985.
21. Mengistu M., Laryea E., Miller A., Wall J. Clinical significance of a new autoantibody against a human muscle soluble antigen, detected by immunofluorescence. Clin. Exp. Immunol. 65: 19, 1986.
22. Fischer S., Heberling H.J., Klugmannk T., Lohmann D., Eichler C.H. Antibodies against various retroorbital eye muscle antigens and sonographic findings in patients with autoimmune orbitopathy. In: Proc. Thyroid Symp., 150th Anniversary of Basedow's Disease (abstract), 1990.
23. Kandror V., Birjukova M., Kryukova I., Mkrtumova N., Konnova E. Some immunological correlations between thyroid pathology and ophthalmopathy. Exp. Clin. Endocrinol. 97: 212, 1991.
24. Triller H., Chungh F., Rodien P., Boucher A., Liberman A., Bernard N.F., Ludgate M., Wall J. Antibodies reactive with an intracellular fragment of a recombinant 64 kDa thyroid and eye muscle protein are associated with thyroid autoimmunity and ophthalmopathy. J. Endocrinol. Invest. 16: 863, 1994.
25. Hiromatsu Y, Fukazawa H., Guinard F., Salvi M., How J., Wall J.R. A thyroid cytotoxic antibody that cross-reacts with an eye muscle cell surface antigen may be the cause of thyroid-associated ophthalmopathy. J. Clin. Endocrinol. Metab. 67: 565, 1988.
26. Hiromatsu Y., Fukazawa H., How J., Wall J.R. Antibody dependent cell mediated cytotoxicity against human eye muscle cells and orbital fibroblasts in Graves' ophthalmopathy - roles of Class II MHC antigen expression and interferon action on effector and target cells. Clin. Exp. Immunol. 70: 593, 1987.
27. HiromatsuY., Cadarso L., Salvi M., Wall J.R. Significance of cytotoxic eye muscle antibodies in patients with thyroid-associated ophthalmopathy. Autoimmunity 5: 205, 1990.
28. Wall J. Nature and significance of eye muscle antigens in endocrine ophthalmopathy. In: Kahaly G. (Ed.), Endocrine Ophthalmopathy. Molecular, Immunological and Clinical Aspects. Dev. Ophthalmol., Karger, Basel, 1993 p. 77.
29. Teboul N., Trillel H., Chun F., Bernard N., Zhan G., Wall J.R. Muscle and species reactivity of mouse monoclonal antibodies to human eye muscle membrane antigens. Clin. Immunol. Immunopathol. 59: 104, 1991.
30. Committees of Regional Thyroid Associations Classification of eye changes of Graves' disease. Thyroid 2: 235, 1992.
31. Nakamura R. Autoantibodies to nuclear antigens (ANA). Advances in laboratory tests and significance in rheumatic disease. Am. Soc. Clin. Pathologists Press, Chicago, 1985, p 3.
32. Laemmlik U.K. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227: 680, 1970.
33. Triller H., Chung F., Tsao M., Bouche A., Rodien P., Liberman A., Bernard. N., Wall J.R. Cross-reactive antibodies in the serum of balb/c mice immunized with thyroid or eye muscle membranes. J. Endocrinol. Invest. 17: 105, 1994.
34. Konstadoulaki M.M., Kroubouzo G., Tosca A., Piperingos G., Marafelia P., Konstadoulakis M., Varelzidis A., Koutras D.A. Thyroid autoantibodies in the subsets of lupus erythematosus: correlation with other autoantibodies and thyroid function. Thyroidology 5: 1, 1993.
35. Gordon T., Isenberg D. Organ specific and multisystem autoimmune disease: Part of a spectrum which may coexist in the same patient. Clin. Rheumatol. 9: 401, 1990.
36. McCombe P.A., Chalk J.B., Pender M.P. Familial occurrence of multiple sclerosis with thyroid disorder and systemic lupus erythematosus. J. Neurol. Sci. 97: 163, 1990.
37. Loviselli A., Velluzzi, F., Pala R., Marcello A., Nurchi P., Mathieu A., Dagenais P., Urowitz M.B., Gladman D.D., Norman C.S. A family study of the antiphospholipid syndrome associated with other autoimmune diseases. J. Rheumatol. 19: 1393, 1992.
38. Loviselli A., Velluzi F., Pala R., Marcello E., Nurchis P., Mathieu A., Bartalena L., Martino E., Grasso L. Circulating antibodies to DNA-related antigens in patients with autoimmune thyroid disorders. Autoimmunity 14: 33, 1992.
39. Tajirik J., Higashi K., Morita M., Ohishi S., Umeda T., Sato T. Elevation of antiDNA antibody titer during thyrotoxic phase of silent thyroiditis. Arch. Intern. Med. 146: 1623, 1986.
40. Katakura M., Yamada T., Aizawak T., HiromatsuA K., Yakimura Y., Ishihara M., Takas N., Maruyamak K., Kanai M., Kobays I. Presence of antideoxyribonucleic acid antibody in patients with hyperthyroidism of Graves' disease. J. Clin. Endocrinol. Metab. 64: 405, 1987.
41. Tachi J., Amino N., Iwatani Y., Mori M., Aozasa M., Tanizaw O., Miyai K. Increase in antideoxiribonucleic acid antibody titer in postpartum aggravation of autoimmune thyroid disease. J. Clin. Endocrinol. Metab. 67: 1049, 1988.
42. Baethge B.A., Levine S.N., Wolf R.E. Antibodies to nuclear antigens in Graves' disease. J. Clin. Endocrinol. Metab. 66: 485, 1988.
43. Moritah S., Arimak T., Matsuda M. Prevalence of nonthyroid specific antibodies in autoimmune thyroid diseases. J. Clin. Endocrinol. Metab. 80: 1203, 1995.
44. Arnaout M.A., Nasarallah N.S., el-Khateeb M.S. Prevalence of abnormal thyroid function tests in connective tissue disease. Scand. J. Rheumatol. 23: 128, 1994.
45. Salvih M., De Chiara F., Gardini E., Minelli R., Bianconi L., Alnovi A., Ricci R., Neri F., Tosi C., Roti E. Echocardiographic diagnosis of pretibial myxedema in patients with autoimmune thyroid disease. Acta Endocrinol. (Copenh.) 131: 113, 1994.
46. Dudgeon L. S., Urquhart A.L. Lymphorrhages in the muscle in exophthalmic goitre. Brain 49: 182, 1975.