Genetic determinants of Graves disease

Molecular Genetics and Metabolism

Volumn 71, Issue 1-2, 2000, Pages 66-69

  Chistyakov, Dimitry A ^a   Savost'anov, Kirill V ^a   Turakulov, Rustam I ^b   Nosikov, Valery V ^a  

^a STATE RESEARCH INSTITUTE OF GENETICS AND SELECTION OF INDUSTRIAL MICROORGANISMS   (Russian Federation)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Association; Genetic markers; Graves disease; Linkage; Suspectibility loci

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; HLA ANTIGEN; THYROTROPIN RECEPTOR;

GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GRAVES DISEASE; HEREDITY; HUMAN; IMMUNOPATHOGENESIS; PATHOGENESIS; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0033803851     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1006/mgme.2000.3042     Document Type: Article

References (41)

1. Autoimmune thyreoiditis in childhood - Epidemiology, clinical and laboratory findings in 61 patients
2. The hereditary and familial aspects of exophthalmic goiter and nodular goiter
3. Hereditary aspects of Graves disease in infancy and childhood
4. Genetics of Graves disease
5. Relative predispositional effects (RPEs) of marker alleles with disease: HLA-DR alleles and Graves disease
6. Two major genes, linked to HLA and Gm, control susceptibility to Graves disease
7. Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease
8. HLA-DRB3 gene alleles in Caucasian patients with Graves disease
9. Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves disease: Replication using a population case control and family-based study
10. Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule
11. Association of the large multifunctional proteasome (LMP2) gene with Graves disease is a result of linkage disequilibrium with the HLA haplotype DRB1*O304-DQB1*02-DQA1*0501
12. Polymorphisms of TAP1 and TAP2 genes in Graves disease
13. The emerging role of CTLA-4 as an immune attenuator
14. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
15. Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups
16. CTLA4 alanine-17 confers genetic susceptibility to Graves disease and to type 1 diabetes mellitus
17. CTLA4 gene polymorphism confers susceptibility to Graves disease in Japanese
18. Association of CTLA-4 gene A-G polymorphism (IDDM12 locus) with acute-onset and insulin-depleted IDDM as well as autoimmune thyroid disease (Graves disease and Hashimoto's thyroiditis) in the Japanese population
19. A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism
20. CTLA-4 gene polymorphism associated with Graves disease in a Caucasian population
21. Complex association analysis of Graves disease using a set of polymorphic markers
22. The cytotoxic T lymphocyte antigen-4 is a major Graves disease locus
23. Association of autoimmune thyroid disease with a microsatellite marker for the thyrotropin receptor gene and CTLA-4 in a Japanese population
24. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry
25. Mapping of a major susceptibility locus for Graves disease (GD-1) to chromosome 14q31
26. Thyroperoxidase microsatellite polymorphism in thyroid diseases
27. Linkage analysis of candidate genes in autoimmune thyroid disease. II. Selected gender-related genes and the X-chromosome
28. Interferon-gamma gene microsatellite polymorphisms in patients with Graves disease
29. Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat
30. Association of Graves disease with an allele of the interleukin-1 receptor antagonist gene
31. Lack of association of Graves disease with the A2 allele of the interleukin-1 receptor antagonist gene in a white European population
32. Lack of an association between alleles of interleukin-1 alpha and interleukin-1 receptor antagonist genes and Graves disease in a North American Caucasian population
33. Microsatellites and PCR primers for genetic studies and genomic sequencing of the human TSH receptor gene
34. Analysis of the thyrotropin receptor as a candidate gene in familial Graves disease
35. Polymorphism of a variant human thyrotropin receptor (hTSHR) gene
36. Multivariate analysis of HLA loci in conjunction with a thyrotropin receptor codon 52 polymorphism in conferring risk of Graves disease
37. Polymorphism of the 52 triplet gene (nucleotide 253) of the TSH receptor in Basedow-Graves patients and in healthy controls
38. No association between a thyrotropin receptor gene polymorphism and Graves disease in the female population
39. Lack of association between polymorphism of the thyrotropin receptor gene and Graves disease in United Kingdom and Hong Kong Chinese patients: Case control and family-based studies
40. Analysis of mutations in exon 1 of the human thyrotropin receptor gene: High frequency of the D36H and P52T polymorphic variants
41. A new Graves disease-susceptibility locus maps to chromosome 20q11.2