메뉴 건너뛰기




Volumn 88, Issue 2, 2003, Pages 176-185

A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma

Author keywords

Angiogenesis; Endothelial cells; Multiple myeloma; Stromal cells; Tumor growth; Vascular endothelial growth factor

Indexed keywords

CYANOCOBALAMIN; IRON; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN B; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; ENDOTHELIAL CELL GROWTH FACTOR; LYMPHOKINE; SIGNAL PEPTIDE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 0038284068     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (142)

References (52)
  • 1
    • 0034979273 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in regulation of physiological angiogenesis
    • Ferrara N. Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am J Physiol Cell Physiol 2001;280:C1358-C66.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Ferrara, N.1
  • 2
    • 19244379078 scopus 로고    scopus 로고
    • Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
    • Carmeliet P, Moons L, Luttun A, Vincenti V, Compernolle V, De Mol M, et al. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 2001;7:575-83.
    • (2001) Nat Med , vol.7 , pp. 575-583
    • Carmeliet, P.1    Moons, L.2    Luttun, A.3    Vincenti, V.4    Compernolle, V.5    De Mol, M.6
  • 5
    • 0034181948 scopus 로고    scopus 로고
    • Signaling pathways induced by vascular endothelial growth factor
    • Larrivee B, Karsan A. Signaling pathways induced by vascular endothelial growth factor. Int J Mol Med 2000;5:447-56.
    • (2000) Int J Mol Med , vol.5 , pp. 447-456
    • Larrivee, B.1    Karsan, A.2
  • 7
    • 0034842967 scopus 로고    scopus 로고
    • Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma
    • Skobe M, Hamberg LM, Hawighorst T, Schirner M, Wolf GL, Alitalo K, et al. Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma. Am J Pathol 2001;159:893-903.
    • (2001) Am J Pathol , vol.159 , pp. 893-903
    • Skobe, M.1    Hamberg, L.M.2    Hawighorst, T.3    Schirner, M.4    Wolf, G.L.5    Alitalo, K.6
  • 8
    • 0035122537 scopus 로고    scopus 로고
    • Induction of tumor lymphanglogenesis by VEGF-C promotes breast cancer metastasis
    • Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, et al. Induction of tumor lymphanglogenesis by VEGF-C promotes breast cancer metastasis. Nat Med 2001;7:192-8.
    • (2001) Nat Med , vol.7 , pp. 192-198
    • Skobe, M.1    Hawighorst, T.2    Jackson, D.G.3    Prevo, R.4    Janes, L.5    Velasco, P.6
  • 9
    • 0035122695 scopus 로고    scopus 로고
    • Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
    • Makinen T, Jussila L, Veikkola T, Karpanen T, Kettunen MI, Pulkkanen KJ, et al. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med 2001;7:199-205.
    • (2001) Nat Med , vol.7 , pp. 199-205
    • Makinen, T.1    Jussila, L.2    Veikkola, T.3    Karpanen, T.4    Kettunen, M.I.5    Pulkkanen, K.J.6
  • 10
    • 0033083962 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies
    • Bellamy WT, Richter L, Frutiger Y, Grogan TM. Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies. Cancer Res 1999;59:728-33.
    • (1999) Cancer Res , vol.59 , pp. 728-733
    • Bellamy, W.T.1    Richter, L.2    Frutiger, Y.3    Grogan, T.M.4
  • 11
    • 0035207927 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in multiple myeloma and other hematopoietic malignancies
    • Bellamy WT. Expression of vascular endothelial growth factor and its receptors in multiple myeloma and other hematopoietic malignancies. Semin Oncol 2001;28:551-9.
    • (2001) Semin Oncol , vol.28 , pp. 551-559
    • Bellamy, W.T.1
  • 12
    • 0035880256 scopus 로고    scopus 로고
    • Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration
    • Podar K, Tai YT, Davies FE, Lentzsch S, Sattler M, Hideshima T, et al. Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration. Blood 2001;98:428-35.
    • (2001) Blood , vol.98 , pp. 428-435
    • Podar, K.1    Tai, Y.T.2    Davies, F.E.3    Lentzsch, S.4    Sattler, M.5    Hideshima, T.6
  • 14
    • 0034655957 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma
    • Dankbar B, Padro T, Leo R, Feldmann B, Kropff M, Mesters RM, et al. Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma. Blood 2000;95:2630-6.
    • (2000) Blood , vol.95 , pp. 2630-2636
    • Dankbar, B.1    Padro, T.2    Leo, R.3    Feldmann, B.4    Kropff, M.5    Mesters, R.M.6
  • 15
    • 0000890276 scopus 로고
    • Multiple myeloma, macroglobulinemia and monoclonal gammapathies
    • Hoffbrand AV, Brain MC, Hirsh J, editors. New York, NY: Churchill Livingstone
    • Durie BGM, Salmon SE. Multiple myeloma, macroglobulinemia and monoclonal gammapathies. In: Hoffbrand AV, Brain MC, Hirsh J, editors. Recent Advances in Hematology. New York, NY: Churchill Livingstone; 1977. p. 243-61.
    • (1977) Recent Advances in Hematology , pp. 243-261
    • Durie, B.G.M.1    Salmon, S.E.2
  • 16
    • 0033134764 scopus 로고    scopus 로고
    • Bone marrow neovascularization, plasma cell angiogenic potential and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma
    • Vacca A, Ribatti D, Presta M, Minischetti M, lurlaro M, Ria R, et al. Bone marrow neovascularization, plasma cell angiogenic potential and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. Blood 1999;93:3064-73.
    • (1999) Blood , vol.93 , pp. 3064-3073
    • Vacca, A.1    Ribatti, D.2    Presta, M.3    Minischetti, M.4    Lurlaro, M.5    Ria, R.6
  • 17
    • 0027257608 scopus 로고
    • The bone marrow of multiple myeloma patients contains B-cell populations at different stages of differentiation that are clonally related to malignant plasma cells
    • Billadeau D, Ahmann G, Greipp P, Van Ness B. The bone marrow of multiple myeloma patients contains B-cell populations at different stages of differentiation that are clonally related to malignant plasma cells. J Exp Med 1993;178:1023-31.
    • (1993) J Exp Med , vol.178 , pp. 1023-1031
    • Billadeau, D.1    Ahmann, G.2    Greipp, P.3    Van Ness, B.4
  • 18
    • 17744370727 scopus 로고    scopus 로고
    • Angiogenesis in multiple myeloma: Correlation between in vitro endothelial colonies growth (CFU-Em) and clinical-biological features
    • Dominici M, Campioni D, Lanza F, Luppi M, Barozzi P, Pauli S, et al. Angiogenesis in multiple myeloma: correlation between in vitro endothelial colonies growth (CFU-Em) and clinical-biological features. Leukemia 2001;15:171-6.
    • (2001) Leukemia , vol.15 , pp. 171-176
    • Dominici, M.1    Campioni, D.2    Lanza, F.3    Luppi, M.4    Barozzi, P.5    Pauli, S.6
  • 19
    • 0036484836 scopus 로고    scopus 로고
    • In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF
    • Valdembri D, Serini G, Vacca A, Ribatti D, Bussolino F. In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF. FASEB J 2002;16:225-7.
    • (2002) FASEB J , vol.16 , pp. 225-227
    • Valdembri, D.1    Serini, G.2    Vacca, A.3    Ribatti, D.4    Bussolino, F.5
  • 23
    • 0034911034 scopus 로고    scopus 로고
    • αVβ3 integrin engagement modulates cell adhesion, proliferation, and protease secretion in human lymphoid tumor cells
    • Vacca A, Ria R, Presta M, Ribatti D, lurlaro M, Merchionne F, et al. αVβ3 integrin engagement modulates cell adhesion, proliferation, and protease secretion in human lymphoid tumor cells. Exp Hematol 2001;29:993-1003.
    • (2001) Exp Hematol , vol.29 , pp. 993-1003
    • Vacca, A.1    Ria, R.2    Presta, M.3    Ribatti, D.4    Lurlaro, M.5    Merchionne, F.6
  • 24
    • 0024503249 scopus 로고
    • Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6
    • Klein B, Zhang XG, Jourdan M, Content J, Houssiau F, Aarden L, et al. Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6. Blood 1989;73:517-26.
    • (1989) Blood , vol.73 , pp. 517-526
    • Klein, B.1    Zhang, X.G.2    Jourdan, M.3    Content, J.4    Houssiau, F.5    Aarden, L.6
  • 25
    • 0024454325 scopus 로고
    • Quantification of cells cultured on 96-well plates
    • Kueng W, Silber E, Eppenberger U. Quantification of cells cultured on 96-well plates. Anal Biochem 1989;182:16-9.
    • (1989) Anal Biochem , vol.182 , pp. 16-19
    • Kueng, W.1    Silber, E.2    Eppenberger, U.3
  • 26
    • 0033058960 scopus 로고    scopus 로고
    • The role of hepatocyte growth factor and its receptor c-Met in multiple myeloma and other blood malignancies
    • Borset M, Seidel C, Hjorth-Hansen H, Waage A, Sundan A. The role of hepatocyte growth factor and its receptor c-Met in multiple myeloma and other blood malignancies. Leuk Lymphoma 1999;32:249-56.
    • (1999) Leuk Lymphoma , vol.32 , pp. 249-256
    • Borset, M.1    Seidel, C.2    Hjorth-Hansen, H.3    Waage, A.4    Sundan, A.5
  • 27
    • 0034517587 scopus 로고    scopus 로고
    • The role of interleukin-6 and interleukin-6/interleukin-6 receptor-α complex in the pathogenesis of multiple myeloma
    • Barillé S, Bataille R, Amiot M. The role of interleukin-6 and interleukin-6/interleukin-6 receptor-α complex in the pathogenesis of multiple myeloma. Eur Cytokine Netw 2000;11:546-51.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 546-551
    • Barillé, S.1    Bataille, R.2    Amiot, M.3
  • 28
    • 0028950484 scopus 로고
    • Cytokine, cytokine receptors, transduction signals, and oncogenes in human multiple myeloma
    • Klein B. Cytokine, cytokine receptors, transduction signals, and oncogenes in human multiple myeloma. Semin Hematol 1995;32:4-19.
    • (1995) Semin Hematol , vol.32 , pp. 4-19
    • Klein, B.1
  • 30
    • 0028798083 scopus 로고
    • A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor (VEGF)
    • Seetharam L, Gotoh N, Maru Y, Neufeld G, Yamaguchi S, Shibuya M. A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor (VEGF). Oncogene 1995;10:135-47.
    • (1995) Oncogene , vol.10 , pp. 135-147
    • Seetharam, L.1    Gotoh, N.2    Maru, Y.3    Neufeld, G.4    Yamaguchi, S.5    Shibuya, M.6
  • 31
    • 0031466232 scopus 로고    scopus 로고
    • The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells
    • Kroll J, Waltenberger J. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem 1997;272:32521-7.
    • (1997) J Biol Chem , vol.272 , pp. 32521-32527
    • Kroll, J.1    Waltenberger, J.2
  • 32
    • 0032158331 scopus 로고    scopus 로고
    • Control of vascular endothelial growth factor angiogenic activity by the extracellular matrix
    • Ortega N, L'Faqihi FE, Plouet J. Control of vascular endothelial growth factor angiogenic activity by the extracellular matrix. Biol Cell 1998;90:381-90.
    • (1998) Biol Cell , vol.90 , pp. 381-390
    • Ortega, N.1    L'Faqihi, F.E.2    Plouet, J.3
  • 33
    • 0034924216 scopus 로고    scopus 로고
    • Angiogenesis research: Guidelines for translation to clinical application
    • Folkman J, Browder T, Palmblad J. Angiogenesis research: guidelines for translation to clinical application. Thromb Haemost 2001;86:23-33.
    • (2001) Thromb Haemost , vol.86 , pp. 23-33
    • Folkman, J.1    Browder, T.2    Palmblad, J.3
  • 34
    • 0035992360 scopus 로고    scopus 로고
    • Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis
    • Rajkumar SV, Mesa RA, Fonseca R, Schroeder G, Plevak MF, Dispenzieri A, et al. Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis. Clin Cancer Res 2002;8:2210-6.
    • (2002) Clin Cancer Res , vol.8 , pp. 2210-2216
    • Rajkumar, S.V.1    Mesa, R.A.2    Fonseca, R.3    Schroeder, G.4    Plevak, M.F.5    Dispenzieri, A.6
  • 35
    • 0035025130 scopus 로고    scopus 로고
    • Decrease of bone marrow angiogenesis in myeloma patients achieving a remission after chemotherapy
    • Sezer O, Niemoller K, Kaufmann O, Eucker J, Jakob C, Zavrski I, et al. Decrease of bone marrow angiogenesis in myeloma patients achieving a remission after chemotherapy. Eur J Haematol 2001;66:238-44.
    • (2001) Eur J Haematol , vol.66 , pp. 238-244
    • Sezer, O.1    Niemoller, K.2    Kaufmann, O.3    Eucker, J.4    Jakob, C.5    Zavrski, I.6
  • 39
    • 0034924201 scopus 로고    scopus 로고
    • Cell-mediated delivery of fibroblast growth factor-2 and vascular endothelial growth factor onto the chick chorioallantoic membrane: Endothelial fenestration and angiogenesis
    • Ribatti D, Nico B, Morbidelli L, Donnini S, Ziche M, Vacca A, et al. Cell-mediated delivery of fibroblast growth factor-2 and vascular endothelial growth factor onto the chick chorioallantoic membrane: endothelial fenestration and angiogenesis. J Vasc Res 2001;38:389-97.
    • (2001) J Vasc Res , vol.38 , pp. 389-397
    • Ribatti, D.1    Nico, B.2    Morbidelli, L.3    Donnini, S.4    Ziche, M.5    Vacca, A.6
  • 41
    • 0034995721 scopus 로고    scopus 로고
    • Microvessel overexpression of aquaporin 1 parallels bone marrow angiogenesis in patients with active multiple myeloma
    • Vacca A, Frigeri A, Ribatti D, Nicchia GP, Nico B, Ria R, et al. Microvessel overexpression of aquaporin 1 parallels bone marrow angiogenesis in patients with active multiple myeloma. Br J Haematol 2001;113:415-21.
    • (2001) Br J Haematol , vol.113 , pp. 415-421
    • Vacca, A.1    Frigeri, A.2    Ribatti, D.3    Nicchia, G.P.4    Nico, B.5    Ria, R.6
  • 42
    • 0030933923 scopus 로고    scopus 로고
    • Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukemia
    • Fiedler W, Graeven U, Ergun S, Verago S, Kilic N, Stockschlader M, et al. Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukemia. Blood 1997;89:1870-5.
    • (1997) Blood , vol.89 , pp. 1870-1875
    • Fiedler, W.1    Graeven, U.2    Ergun, S.3    Verago, S.4    Kilic, N.5    Stockschlader, M.6
  • 43
    • 0037085765 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy
    • Dias S, Choy M, Alitalo K, Rafii S. Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood 2002;99:2179-84.
    • (2002) Blood , vol.99 , pp. 2179-2184
    • Dias, S.1    Choy, M.2    Alitalo, K.3    Rafii, S.4
  • 45
    • 18544377343 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-induced migration of multiple myeloma cells is associated with β1-integrin- and P13-kinase-dependent PKCα activation
    • Podar K, Tai YT, Lin BK, Narsimhan RP, Sattler M, Kijima T, et al. Vascular endothelial growth factor (VEGF)-induced migration of multiple myeloma cells is associated with β1-integrin- and P13-kinase-dependent PKCα activation. J Biol Chem 2002;277:7875-81.
    • (2002) J Biol Chem , vol.277 , pp. 7875-7881
    • Podar, K.1    Tai, Y.T.2    Lin, B.K.3    Narsimhan, R.P.4    Sattler, M.5    Kijima, T.6
  • 46
    • 0029155712 scopus 로고
    • Vascular permeability factor (vascular endothelial growth factor) expression in cervical neoplasia
    • Guidi AJ, Abu-Jawdeh G, Berse B, Jackman RW, Tognazzi K, Dvorak HF, et al. Vascular permeability factor (vascular endothelial growth factor) expression in cervical neoplasia. J Natl Cancer Inst 1995;87:1237-45.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1237-1245
    • Guidi, A.J.1    Abu-Jawdeh, G.2    Berse, B.3    Jackman, R.W.4    Tognazzi, K.5    Dvorak, H.F.6
  • 47
    • 0029929046 scopus 로고    scopus 로고
    • Strong expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in ovarian borderline and malignant neoplasm
    • Abu-Jawdeh G, Faix JD, Niloff J, Tognazzi K, Manseau E, Dvorak HF, et al. Strong expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in ovarian borderline and malignant neoplasm. Lab Invest 1996;74:1105-15.
    • (1996) Lab Invest , vol.74 , pp. 1105-1115
    • Abu-Jawdeh, G.1    Faix, J.D.2    Niloff, J.3    Tognazzi, K.4    Manseau, E.5    Dvorak, H.F.6
  • 48
    • 0030908887 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in normal liver and hepatocellular carcinoma: An immunohistochemical study
    • Chow NH, Hsu PI, Lin XZ, Yang HB, Chan SH, Cheng KS, et al. Expression of vascular endothelial growth factor in normal liver and hepatocellular carcinoma: an immunohistochemical study. Hum Path 1997;28:698-703.
    • (1997) Hum Path , vol.28 , pp. 698-703
    • Chow, N.H.1    Hsu, P.I.2    Lin, X.Z.3    Yang, H.B.4    Chan, S.H.5    Cheng, K.S.6
  • 49
    • 0036493522 scopus 로고    scopus 로고
    • Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
    • Zhan F, Hardin J, Kordsmeier B, Bumm K, Zheng M, Tian E, et al. Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells. Blood 2002;99:1745-57.
    • (2002) Blood , vol.99 , pp. 1745-1757
    • Zhan, F.1    Hardin, J.2    Kordsmeier, B.3    Bumm, K.4    Zheng, M.5    Tian, E.6
  • 50
    • 0035121440 scopus 로고    scopus 로고
    • Serum levels of the angiogenic cytokines basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in multiple myeloma
    • Sezer O, Jacob C, Euker J, Niemoller K, Gatz F, Wernecke K, et al. Serum levels of the angiogenic cytokines basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in multiple myeloma. Eur J Haematol 2001;66:83-8.
    • (2001) Eur J Haematol , vol.66 , pp. 83-88
    • Sezer, O.1    Jacob, C.2    Euker, J.3    Niemoller, K.4    Gatz, F.5    Wernecke, K.6
  • 51
    • 0036122019 scopus 로고    scopus 로고
    • Clinical significance of vascular endothelial growth factor and hepatocyte growth factor in multiple myeloma
    • Iwasaki T. Hamano T, Ogata A, Hashimoto N, Kitano M, Kakishita E. Clinical significance of vascular endothelial growth factor and hepatocyte growth factor in multiple myeloma. Br J Haematol 2002;116:796-802.
    • (2002) Br J Haematol , vol.116 , pp. 796-802
    • Iwasaki, T.1    Hamano, T.2    Ogata, A.3    Hashimoto, N.4    Kitano, M.5    Kakishita, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.