Engraftment and dissemination of T lymphocytes from primary haemophagocytic lymphohistiocytosis in scid mice

British Journal of Haematology

Volumn 121, Issue 2, 2003, Pages 349-358

  Yoshida, Nobuyuki ^a   Ishii, Eiichi ^a   Oshima, Koichi ^b   Yanai, Fumio ^b   Ogawa, Atushi ^c   Kataoka, Satoshi ^c   Sako, Masahiro ^d   Park, Yong Dong ^e   Koide, Kayoko ^a   Imayoshi, Miyoko ^a   Zaitsu, Masafumi ^a   Muraoka, Kenji ^a   Hamasaki, Yuhei ^a   Imashuku, Shinsaku ^f   Yasukawa, Masaki ^g  

^a SAGA UNIVERSITY   (Japan)

^b FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Niigata Hosp   (Japan)

^d OSAKA CITY GENERAL HOSPITAL   (Japan)

^e NARA MEDICAL UNIVERSITY HOSPITAL   (Japan)

^f Kyoto City Institute of Health and Environmental Sciences   (Japan)

^g EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Haemophagocytic lymphohistiocytosis; Perforin; Scid mice; T lymphocytes

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CHLORDANE; HLA DR ANTIGEN; PERFORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD; BLOOD DISEASE; BRAIN; CASE REPORT; CELL PROLIFERATION; CONTROLLED STUDY; ERYTHROPHAGOCYTOSIS; FEMALE; GENETIC DISORDER; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HERPES VIRUS SAIMIRI; HUMAN; HUMAN CELL; LUNG; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PATHOGENESIS; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; SCID MOUSE; SOUTHERN BLOTTING; T LYMPHOCYTE;

ANIMALS; BLOTTING, SOUTHERN; BRAIN; CASE-CONTROL STUDIES; CELL LINE, TRANSFORMED; CELL MOVEMENT; CLONE CELLS; CYTOTOXICITY TESTS, IMMUNOLOGIC; FEMALE; FLOW CYTOMETRY; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; INFANT; LUNG; MICE; MICE, SCID; MODELS, ANIMAL; T-LYMPHOCYTES;

EID: 0038217016     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04273.x     Document Type: Article

References (42)

1. Arico, M., Danesino, C., Pende, D. & Moretta, L. (1991) Pathogenesis of haemophagocytic lymphohistiocytosis. British Journal of Haematology, 114, 761-769.
2. Broker, B.M., Kraft, M.S., Klausenberg, U., Le Deist, F., de Villartay, J.P., Fleckenstein, B., Fleischer, B. & Meinl, E. (1997) Activation induces apoptosis in Herpesvirus saimiri-transformed T cells independent of CD95 (Fas, APO-1). European Journal of Immunology, 27, 2774-2780.
3. Broker, B.M., Tsygankov, A.Y., Fickenscher, H., Chitaev, N.A., Muller-Fleckenstein, I., Fleckenstein, B., Bolen, J.B., Emmrich, F. & Schulze-Koops, H. (1994) Engagement of the CD4 receptor inhibits the interleukin-2-dependent proliferation of human T cells transformed by Herpesvirus saimiri. European Journal of Immunology, 24, 843-850.
4. Broker, B.M., Tsygankov, A.Y., Muller-Fleckenstein, I., Guse, A.H., Chitaev, N.A., Biesinger, B., Fleckenstein, B. & Emmrich, F. (1993) Immortalization of human T cell clones by Herpesvirus saimiri. Signal transduction analysis reveals functional CD3, CD4, and IL-2 receptors. Journal of Immunology, 151, 1184-1192.
5. Cabanillas, J.A., Cambronero, R., Pacheco-Castro, A., Garcia-Rodirguez, M.C., Martin-Fernandez, J.M., Fontan, G. & Regueiro, J.R. (2002) Characterization of Herpesvirus Saimiri-transformed T lymphocytes from common variable immunodeficiency patients. Clinical and Experimental Immunology, 127, 366-373.
6. Davis, J.E., Smyth, M.J. & Trapani, J.A. (2001) Granzyme A- and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity. European Journal of Immunology, 31, 39-47.
7. Dufourcq-Lagelouse, R., Jabado, N., Le Deist, F., Stephan, J.L., Souillet, G., Bruin, M., Vilmer, E., Schneider, M., Janka, G., Fischer, A. & de Saint Basile, G. (1999a) Linkage of familial hemophagocytic lymphohistiocytosis to 10q21-22 and evidence for heterogeneity. American Journal of Human Genetics, 64, 172-179.
8. Dufourcq-Lagelouse, R., Pastural, E., Barrat, F.J., Feldmann, J., Le Deist, F., Fischer, A. & De Saint Basile, G. (1999b) Genetic basis of hemophagocytic syndrome. International Journal of Molecular Medicine, 4, 127-133.
9. Fadeel, B., Orrenius, S. & Hentewr, J.I. (1999) Induction of apoptosis and caspase activation in cells obtained from familial haemophagocytic lymphohistiocytosis patients. British Journal of Haematology, 106, 406-415.
10. Filipovich, A.H. (1997) Hemophagocytic lymphohistiocytosis: a lethal disorder of immune regulation. Journal of Pediatrics, 130, 337-338.
11. Hansmann, M.L., Rontogianni, D., Janka-Schaub, G.E., Wacker, H.H., Hinkeldey, K. & Radzun, H.J. (1989) Familial hemophagocytic lymphohistiocytosis macrophages showing immunohistochemical properties of activated macrophages and T-accessory cells. Pediatric Hematology and Oncology, 6, 237-246.
12. Henter, J.I. (2002) Biology and treatment of familial hemophagocytic lymphohistiocytosis: importance of perforin in lymphocyte-mediated cytotoxicity and triggering of apoptosis. Medical and Pediatric Oncology, 38, 305-309.
13. Henter, J.I., Arico, M., Egeler, R.M., Elinder, G., Favara, B.E., Filipovich, A.H., Gadner, H., Imashuku, S., Janka-Schaub, G., Komp, D., Ladisch, S. & Webb, D. (1997) HLH94: a treatment protocol for hemophagocytic lymphohitiocytosis. HLH Study Group of the Histiocyte Society. Medical and Pediatric Oncology, 28, 342-347.
14. Henter, J.I. & Elinder, G. (1992) Cerebromeningeal haemophagocytic lymphohistiocytosis. Lancet, 339, 104-107.
15. Henter, J., Elinder, G. & Ost, A. (1991a) Diagnostic guidelines for hemophagocytic lymphohistiocytosis. Seminars in Oncology, 18, 29-33.
16. Henter, J., Elinder, G., Soder, O., Hansson, M., Andersson, B. & Andersson, U. (1991b) Hypercytokinemia in familial hemophagocytic lymphohistiocytosis. Blood, 78, 2918-2922.
17. Imashuku, S., Hibi, S. & Todo, S. (1997) Hemophagocytic lymphohistiocytosis in infancy and childhood. Journal of Pediatrics, 130, 352-357.
18. Imashuku, S., Hyakuna, N., Funabiki, T., Ikuta, K., Sako, M., Iwai, A., Fukushima, T., Kataoka, S., Yabe, M., Muramatsu, K., Kohdera, U., Nakadate, H., Kitazawa, K., Toyoda, Y. & Ishii, E. (2002) Low natural killer activity and central nervous system disease as a high-risk prognostic indicator for young patients with hemophagocytic lymphohistiocytosis (HLH). Cancer, 94, 3023-3031.
19. Ishii, E., Hara, T., Ohga, S., Ueda, K., Suda, M., Nakamura, J., Yanagi, T. & Tsuji, Y. (1987) Familial erythrophagocytic lymphohistiocytosis: surface marker analysis using monoclonal antibodies. European Journal of Haematology, 38, 63-66.
20. Ishii, E. & Kimura, N. (1998) Familial hemophagocytic lymphohistiocytosis. Hematological disorders in infancy. International Journal of Pediatric Hematology and Oncology, 6, 147-155.
21. Ishii, E., Ohga, S., Tanimura, M., Imashuku, S., Sako, M., Mizutani, S. & Miyazaki, S. (1998) Clinical and epidemiologic studies of familial hemophagocytic lymphohistiocytosis in Japan. Medical and Pediatric Oncology, 30, 276-283.
22. Ishii, E., Yoshida, N., Kimura, N., Fujimoto, J., Mizutani, S., Sako, M., Hibi, S., Nagano, M., Yoshida, T., Mori, T., Kiyokawa, N., Mohri, S., Tanaka, T., Miyazaki, S. & Hara, T. (1999) Clonal dissemination of T lymphocytes in scid mice from familial hemophagocytic lymphohistiocytosis. Medical and Pediatric Oncology, 32, 201-208.
23. Jabado, N., de Graeff-Meeder, E.R., Cavazzana-Calvo, M., Haddad, E., Le Deist, F., Benkerrou, M., Dufourcq, R., Caillat, S., Blanche, S. & Fischer, A. (1997) Treatment of familial hemophagocytic lymphohistiocytosis with bone marrow transplantation from HIA genetically nonidentical donors. Blood, 90, 4743-4748.
24. Janka, G.E. (1983) Familial erythrophagocytic lymphohistiocytosis. European Journal of Pediatrics, 140, 221-230.
25. Janka, G.E. (1989) Familial hemophagocytic lymphohistiocytosis: diagnostic problems and differential diagnosis. Pediatric Hematology and Oncology, 6, 219-225.
26. Knappe, A., Feldmann, G., Dittmer, U., Meinl, E., Nisslein, T., Wittmann, S., Matz-Rensing, K., Kirchner, T., Bodemer, W. & Fickenscher, H. (2000) Herpesvirus saimiri-transformed macaque T cells are tolerated and do not cause lymphoma after autologous reinfusion. Blood, 95, 3256-3261.
27. Loechelt, B.J., Egeler, M., Filipovich, A.H., Jyonouchi, H. & Shapiro, R.S. (1994) Immunosuppression: preliminary results of alternative maintenance therapy for familial hemophagocytic lymphohistiocytosis. Medical and Pediatric Oncology, 22, 325-328.
28. Loy, T.S., Diaz-Arias, A.A. & Perry, M.C. (1991) Familial erythrophagocytic lymphohistiocytosis. Seminars in Oncology, 18, 34-39.
29. Mittrucker, H.W., Muller-Fleckenstein, I., Fleckenstein, B. & Fleischer, B. (1993) Herpes virus saimiri-transformed human T lymphocytes: normal functional phenotype and preserved T cell receptor signaling. International Journal of Immunology, 5, 985-990.
30. Nagano, M., Kimura, N., Ishii, E., Yoshida, N., Yoshida, T., Sako, M., Hibi, S., Imashuku, S., Miyazaki, S., Hara, T. & Mizutani, S. (1999) Clonal expansion of αβ-T lymphocytes with inverted Jβ1 bias in familial hemophagocytic lymphohistiocytosis. Blood, 94, 2374-2382.
31. Ohadi, M., Lalloz, M.R., Sham, P., Zhao, J., Dearlove, A.M., Shiach, C., Kinsey, S., Rhodes, M. & Layton, D.M. (1999) Localization of a gene for familial hemophagocytic lymphohistiocytosis at chromosome 9q21.3-22 by homozygosity mapping. American Journal of Human Genetics, 64, 165-171.
32. Oshima, K., Muta, K., Nakashima, M., Haraoka, S., Tutiya, T., Suzumiya, J., Kawasaki, C., Watanabe, T. & Kikuchi, M. (2001) Expression of human tumor-associated antigen RCAS1 in Reed-Sternberg cells in association with Epstein-Barr virus infection: a potential mechanism of immune evasion. International Journal of Cancer, 93, 91-96.
33. Oshima, K., Shimazaki, K., Kume, T., Suzumiya, J., Kanda, M. & Kikuchi, M. (1998) Perforin and Fas pathways of cytotoxic T-cells in histiocytic necrotizing lymphadenitis. Histopathology, 33, 471-478.
34. Rodriguez-Gallego, C., Corell, A., Pacheco, A., Timon, M., Regueiro, J.R., Allende, L.M., Madrono, A. & Arnaiz-Villena, A. (1996) Herpes virus saimiri transformation of T cells in CD3 gamma immunodeficiency: phenotypic and functional characterization. Journal of Immunological Methods, 198, 177-186.
35. Saxon, A., Macy, E., Denis, K., Tary-Lehmann, M., Witte, O. & Braun, J. (1991) Limited B cell repertoire in severe combined immunodeficient mice engrafted with peripheral blood mononuclear cells derived from immunodeficient or normal humans. Journal of Clinical Investigation, 87, 658-665.
36. Stephan, V., Wahn, V., Le Deist, F., Dirksen, U., Broker, B., Muller-Fleckenstein, I., Horneff, G., Schroten, H., Fischer, A. & de Saint Basile, G. (1996) Atypical X-linked severe combined immunodeficiency due to possible spontaneous reversion of the genetic defect in T cells. New England Journal of Medicine, 335, 1563-1567.
37. Stepp, S.E., Dufourcq-Lagelouse, R., Le Deist, F., Bhawan, S., Certain, S., Mathew, P.A., Henter, J.I., Bennett, M., Fischer, A., de Saint Basile, G. & Kumar, V. (1999) Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science, 286, 1957-1959.
38. Suga, N., Takada, H., Nomura, A., Ohga, S., Ishii, E., Ihara, K., Oshima, K. & Hara, T. (2002) Perforin defects of primary haemophagocytic lymphohistiocytosis in Japan. British Journal of Haematology, 116, 346-349.
39. Torbett, B.E., Picchio, G. & Mosier, D. (1991) Hu-PBL-SCID: a model for human immune function, AIDS, and lymphomagenesis. Immunological Review, 124, 139-164.
40. Yasukawa, M., Inatsuki, A., Horiuchi, T. & Kobayashi, Y. (1991) Functional heterogeneity among herpes simplex virus-specific human CD4+ T cells. Journal of Immunology, 146, 1341-1347.
41. Yasukawa, M., Inoue, Y., Kimura, N. & Fujita, S. (1995) Immortalization of human T cells expressing T-cell receptor-γδ by Herpesvirus saimiri. Journal of Virology, 69, 8114-8117.
42. Yoshida, N., Ishii, E., Nomizu, M., Yamada, Y., Mohri, S., Kinukawa, N., Matsuzaki, A., Oshima, K., Hara, T. & Miyazaki, S. (1999) The laminin-derived peptide YIGSR (Tyr-Ile-Gly-Ser-Arg) inhibits human pre-B leukemic growth and dissemination to organs in scid mice. British Journal of Cancer, 80, 1898-1904.