Perforin and Fas pathways of cytotoxic T-cells in histiocytic necrotizing lymphadenitis

Histopathology

Volumn 33, Issue 5, 1998, Pages 471-478

  Ohshima, K ^a   Shimazaki, K ^a   Kume, T ^a   Suzumiya, J ^a   Kanda, M ^a   Kikuchi, M ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Fas; Histiocytic necrotizing lymphadenitis; Perforin

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; FAS LIGAND; PERFORIN;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; HELPER CELL; HISTIOCYTE; HUMAN; HUMAN TISSUE; KIKUCHI DISEASE; MALE; PRIORITY JOURNAL; SCHOOL CHILD; T LYMPHOCYTE SUBPOPULATION;

ADOLESCENT; ADULT; ANTIGENS, CD; ANTIGENS, CD95; APOPTOSIS; CHILD; FAS LIGAND PROTEIN; FEMALE; FLOW CYTOMETRY; HISTIOCYTIC NECROTIZING LYMPHADENITIS; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; MALE; MEMBRANE GLYCOPROTEINS; PORE FORMING CYTOTOXIC PROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0031793926     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.1998.00532.x     Document Type: Article

References (25)

1. Wyllie AH. Cell death: a new classification separating apoptosis from necrosis. In Bowen ID & Lockshin RA eds. Cell Death in Biology and Pathology Chapman Hall, London, 1981; 9-34.
2. Vaux DL. Toward an understanding of the molecular mechanisms of physiological cell death. Proc. Natl. Acad. Sci. USA 1993; 90; 786-789.
3. Cohen JJ. Apoptosis. Immunol. Today 1993; 14; 126-136.
4. Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytes: a clinicopathological study (in Japanese). Acta Hematol. Jpn 1972; 35; 379-380.
5. Ohshima K, Kikuchi M, Sumiyoshi Y et al. Proliferating cells in histiocytic necrotizing lymphadenitis. Virchows Arch. B 1991; 61; 97-100.
6. Liu Q, Ohshima K, Shinohara T, Kikuchi M. Apoptosis in histiocytic necrotizing lymphadenitis. Pathol. Int. 1995; 45; 729-734.
7. Kägi D, Vignaux F, Ledermann B et al. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science 1994; 265; 528-530.
8. Shiver JW, Su L, Hankart PA. Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A. Cell 1992; 71; 315-322.
9. 2+-independent T cell-mediated cytotoxicity. J. Exp Med. 1993; 177; 195-200.
10. Trauth BC, Klas C, Peters AMJ et al. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 1989; 245; 301.
11. Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993; 75; 1169-1178.
12. Lowin B, Hahne M, Mattmann C. Cytolytic T cell-cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 1994; 370; 650-652.
13. Takakuwa T, Ohnuma S, Koike M, Hoshikawa M, Koizumi H. Involvement of cell-mediated killing in apoptosis in histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease). Histopathology 1996; 28; 41-48.
14. Mori N, Yatabe Y, Asai J, Nagasawa T. Immunohistochemical study of necrotizing lymphadenitis: A possible mechanism for apoptosis involving perforin and granzyme-producing cytotoxic T cells. Pathol. Int. 1997; 47; 31-37.
15. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 1992; 119; 493-501.
16. Felgar RE, Furth EE, Wasik MA, Gluckman SJ, Salhany KE. Histiocytic necrotizing lymphadenitis (Kikuchi's disease): In situ end-labeling, immunohistochemical and serologic evidence supporting cytotoxic lymphocyte-mediated apoptotic cell death. Mod. Pathol. 1997; 10; 231-241.
17. Ohshima K, Shimazaki K, Suzumiya J, Kanda M, Kumagawa M, Kikuchi M. Apoptosis of cytotoxic T-cells in histiocytic necrotizing lymphadenitis. Virchow Arch. 1998 (in press).
18. Moss DJ, Bishop CJ, Burrows SR, Ryan JM. T lymphocytes in infectious mononucleosis. 1. T cell death in vitro. Clin. Exp. Immunol. 1985; 60; 61-69.
19. Razvi ES, Welsh RM. Programmed cell death of T lymphocytes during acute viral infection: a mechanism for virus-induced immune deficiency. J. Virol. 1993; 67; 5754-5765.
20. Liles WC, Kiener PA, Ledbetter JA, Aruffo A, Klebanoff S. Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils. J. Exp. Med. 1996; 184; 429-440.
21. Badley AD, Mcelhinny JA, Leibson PJ, Lynch DH, Alderson MR, Paya CV. Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes. J. Virol. 1996; 70; 199-206.
22. Kiener PA, Davis PM, Starling GC, Mehlin C, Klebanoff SJ, Ledbetter Liles WC. Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages. J. Exp. Med. 1997; 185; 1511-1516.
23. Kikuchi M, Sumiyoshi Y, Minamishima Y et al., Kikuchi's disease (histiocytic necrotizing lymphadenitis). In Ablashi DV, Krueger GRF, Salahuddin SZ eds. Human Herpesvirus-6. Amsterdam: Elsevier Science Publishers B.V., 1992; 175-183.
24. Takada K, Iwanga M, Osato T, Mikuni C, Kawamura T, Miyake T. Elevated antibody titers to Epstein-Barr virus in subacute necrotizing lymphadenitis (in Japanese). Igaku No Ayumi 1980; 112; 194-196.
25. Sumiyoshi Y, Kikuchi M, Ohshima K et al. Human herpsevirus-6 genomes in histiocytic lymphadenitis (Kikuchi's disease) and other forms of lymphadenitis. Am. J. Clin. Pathol. 1993; 99; 609-614.