Fragile X (CGG)n repeats induce a transcriptional repression in cis upon a linked promoter: Evidence for a chromatin mediated effect

BMC Molecular Biology

Volumn 4, Issue , 2003, Pages

  Chandler, Simon P ^a,b   Kansagra, Pushpa ^c   Hirst, Mark C ^c  

^a SANGAMO BIOSCIENCES INC   (United States)

^b UNIVERSITY OF PORTSMOUTH   (United Kingdom)

^c OPEN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN; HISTONE DEACETYLASE; MESSENGER RNA; THYMIDINE KINASE; TRICHOSTATIN A; CYTOSINE; ENZYME INHIBITOR; FXR1 PROTEIN, HUMAN; GUANINE; HYDROXAMIC ACID; RNA BINDING PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CHROMATIN; CONTROLLED STUDY; DEACETYLATION; GENE REPRESSION; GENE SEQUENCE; GENE SILENCING; GENETIC TRANSCRIPTION; IN VITRO STUDY; NONHUMAN; OOCYTE; PLASMID; PROMOTER REGION; PROTEIN METHYLATION; TRANSCRIPTION REGULATION; XENOPUS LAEVIS; ANIMAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FRAGILE X SYNDROME; GENE EXPRESSION REGULATION; GENETIC LINKAGE; GENETICS; HERPES SIMPLEX VIRUS 1; HUMAN; METABOLISM; PHYSIOLOGY; REPORTER GENE; TRINUCLEOTIDE REPEAT; VIRUS GENE;

XENOPUS LAEVIS;

ANIMALS; CHROMATIN; CYTOSINE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FRAGILE X SYNDROME; GENE EXPRESSION REGULATION; GENE SILENCING; GENES, REPORTER; GENES, VIRAL; GUANINE; HERPESVIRUS 1, HUMAN; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; LINKAGE (GENETICS); OOCYTES; PLASMIDS; PROMOTER REGIONS (GENETICS); RNA-BINDING PROTEINS; THYMIDINE KINASE; TRANSCRIPTION, GENETIC; TRINUCLEOTIDE REPEAT EXPANSION; VIRAL STRUCTURAL PROTEINS; XENOPUS LAEVIS;

EID: 0038150132     PISSN: 14712199     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2199-4-3     Document Type: Article

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