The human 20-kDa 5'-(CGG)(n)-3'-binding protein is targeted to the nucleus and affects the activity of the FMR1 promoter

Journal of Biological Chemistry

Volumn 275, Issue 9, 2000, Pages 6447-6452

  Müller Hartmann, Herbert ^a   Deissler, Heidrun ^a   Naumann, Frauke ^a   Schmitz, Birgit ^a   Schröer, Jörg ^a   Doerfler, Walter ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CGG REPEAT BINDING PROTEIN; COMPLEMENTARY DNA; DNA BINDING PROTEIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PROTEIN P20; REPETITIVE DNA; RNA 28S; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA METHYLATION; DNA TRANSFECTION; FRAGILE X SYNDROME; GENE FUNCTION; HELA CELL; HUMAN; HUMAN CELL; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PEPTIDE MAPPING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN TARGETING; SEQUENCE ANALYSIS; TELOMERE;

AMINO ACID SEQUENCE; CELL NUCLEUS; CHROMOSOMES; DNA-BINDING PROTEINS; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; LUMINESCENT PROTEINS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NUCLEAR LOCALIZATION SIGNALS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE DELETION; TELOMERE; TRANSFECTION;

EID: 0343415658     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.9.6447     Document Type: Article

References (29)

1. Warren, S. T., and Nelson, D. L. (1993) Curr. Opin. Neurobiol. 3, 752-759
2. Warren, S. T. (1996) Science 271, 1374-1375
3. Ashley, C. T., Jr., and Warren, S. T. (1995) Annu. Rev. Genet. 29, 703-728
4. Pieretti, M., Zhang, F. P., Fu, Y. H., Warren, S. T., Oostra, B. A., Caskey, C. T., and Nelson, D. L. (1991) Cell 66, 817-822
5. Verkerk, A. J. M. H., Pieretti, M., Sutcliffe, J. S., Fu, Y.-H., Kuhl, D. P. A., Pizutti, A., Reiner, O., Richards, S., Victoria, M. F., Zhang, F. P., Eussen, B. E., van Ommen, G.-J. B., Blonden, L. A. J., Riggins, G. J., Chastain, J. L., Kunst, C. B., Galjaard, H., Caskey, C. T., Nelson, D. L., Oostra, B. A., and Warren, S. T. (1991) Cell 65, 905-914
6. Chung, M. Y., Ranum, L. P., Duvick, L. A. Servadio, A., Zoghbi, H. Y., and Orr, H. T. (1993) Nat. Genet. 5, 254-258
7. The Huntington's Disease Collaborative Research Group (1993) Cell 72, 971-983
8. Mandel, J. L., and Heitz, D. (1992) Curr. Opin. Genet. Dev. 2, 422-430
9. Warren, S. T., and Nelson, D. L. (1994) J. Am. Med. Assoc. 271, 536-542
10. Smeets, H. J., Smits, A. P., Verheij, C. E., Theelen, J. P., Willemsen, R., van de Burgt, I., Hoogeveen, A. T., Oosterwijk, J. C., and Oostra, B. A. (1995) Hum. Mol. Genet. 4, 2103-2108
11. Chiurazzi, P., Pomponi, M. G., Willemsen, R., Oostra, B. A., and Neri, G. (1998) Hum. Mol. Genet. 7, 109-113
12. Devys, D., Lutz, Y., Rouyer, N., Bellocq, J. P., and Mandel, J. L. (1993) Nat. Genet. 4, 335-340
13. Behn-Krappa, A., and Doerfler, W. (1994) Hum. Mutat. 3, 19-24
14. Chen, X., Mariappan, S. V., Catasti, P., Ratliff, R., Moyzis, R. K., Laayoun, A., Smith, S. S., Bradbury, E. M., and Gupta, G. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5199-5203
15. Wells, R. D., Parniewski, P., Pluciennik, A., Bacolla, A., Gellibolian, R., and Jaworski, A. (1998) J. Biol. Chem. 273, 19532-19541
16. Deissler, H., Behn-Krappa, A., and Doerfler, W. (1996) J. Biol. Chem. 271, 4327-4334
17. Deissler, H., Wilm, M., Genç, B., Schmitz, B., Ternes, T., Naumann, F., Mann, M., and Doerfler, W. (1997) J. Biol. Chem. 272, 16761-16768
18. Dingwall, C., and Laskey, R. A. (1991) Trends Biochem. Sci. 16, 478-481
19. Makkerh, J. P. S., Dingwall, C., and Laskey, R. A. (1996) Curr. Biol. 6, 1025-1027
20. Shimizu, M., Gellibolian, R., Oostra, B. A., and Wells, R. D. (1996) J. Mol. Biol. 258, 614-626
21. Muiznieks, I., and Doerfler, W. (1994) FEBS Lett. 344, 251-254
22. Higuchi, R. (1990) in PCR Protocols: A Guide to Methods and Applications (Innis, M. A., Gelfand, D. H., Sninsky, J. J., and White, T. J., eds) pp. 177-183, Academic Press, Inc., San Diego, CA
23. Bablanian, R., Eggers, H. J., and Tamm, I. (1965) Virology 26, 100-113
24. Williams, M., Brys, A., Weiner, A. M., and Maizels, N. (1992) Nucleic Acids Res. 20, 4935-4936
25. Gonzalez, I. L., and Sylvester, J. E. (1995) Genomics 27, 320-328
26. Siebert, P. D., and Larrick, J. W. (1993) BioTechniques 14, 244-249
27. Hilger-Eversheim, K., and Doerfler, W. (1997) Cancer Res. 57, 3001-3009
28. Henderson, A. S., Warburton, D., and Atwood, K. C. (1972) Proc. Natl. Acad. Sci. U. S. A. 69, 3394-3398
29. Evans, H. J., Buckland, R. A., and Pardue, M. L. (1974) Chromosoma 48, 405-426