메뉴 건너뛰기




Volumn 23, Issue 12, 2003, Pages 4996-5003

ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity

Author keywords

Adenosine; ATP; Glutamate; GTP; Hippocampus; Kainate; Neurotoxicity; NMDA receptor; P2 receptor

Indexed keywords

ADENOSINE; ADENOSINE PHOSPHATE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE; GLUTAMIC ACID; GUANOSINE TRIPHOSPHATE; IFENPRODIL; INOSINE TRIPHOSPHATE; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NMDA RECEPTOR NR1A; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

EID: 0038113411     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-12-04996.2003     Document Type: Article
Times cited : (35)

References (55)
  • 1
    • 0032970382 scopus 로고    scopus 로고
    • Guanine nucleotides, including GMP, antagonize kainate responses in Xenopus oocytes injected with chick cerebellar membranes
    • Aleu J, Barat A, Burgos JS, Solsona C, Marsal J, Ramirez G (1999) Guanine nucleotides, including GMP, antagonize kainate responses in Xenopus oocytes injected with chick cerebellar membranes. J Neurochem 72:2170-2176.
    • (1999) J Neurochem , vol.72 , pp. 2170-2176
    • Aleu, J.1    Barat, A.2    Burgos, J.S.3    Solsona, C.4    Marsal, J.5    Ramirez, G.6
  • 2
    • 0024336479 scopus 로고
    • Guanine nucleotides are competitive inhibitors of N-Methyl-D-aspartate and its receptor site both in vitro and in vivo
    • Baron MD, Dudley MW, McCarthy DR, Miller FP, Reynolds IJ, Schmidt CJ (1989) Guanine nucleotides are competitive inhibitors of N-Methyl-D-aspartate and its receptor site both in vitro and in vivo. J Pharmacol Exp Ther 250:162-169.
    • (1989) J Pharmacol Exp Ther , vol.250 , pp. 162-169
    • Baron, M.D.1    Dudley, M.W.2    McCarthy, D.R.3    Miller, F.P.4    Reynolds, I.J.5    Schmidt, C.J.6
  • 3
    • 0027226219 scopus 로고
    • Optimized survival of hippocampal neurons in B27-supplemented Neurobasal™, a new serum-free medium combination
    • Brewer GJ, Torricelli JR, Evege EK, Price PJ (1993) Optimized survival of hippocampal neurons in B27-supplemented Neurobasal™, a new serum-free medium combination. J Neurosci Res 35:567-576.
    • (1993) J Neurosci Res , vol.35 , pp. 567-576
    • Brewer, G.J.1    Torricelli, J.R.2    Evege, E.K.3    Price, P.J.4
  • 4
    • 0025765694 scopus 로고
    • GDPβS antagonizes whole cell current responses to excitatory amino acids
    • Budson AE, Jackson PS, Lipton SA (1991) GDPβS antagonizes whole cell current responses to excitatory amino acids. Brain Res 548:346-348.
    • (1991) Brain Res , vol.548 , pp. 346-348
    • Budson, A.E.1    Jackson, P.S.2    Lipton, S.A.3
  • 5
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • Cull-Candy S, Brickley S, Farrant M (2001) NMDA receptor subunits: diversity, development and disease. Curr Opin Neurobiol 11:327-335.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 6
    • 0032521330 scopus 로고    scopus 로고
    • Inhibition by ATP of hippocampal synaptic transmission requires localized extracellular catabolism by ecto-nucleotidases into adenosine and channeling to adenosine A(1) receptors
    • Cunha RA, Sebastiao AM, Ribeiro JA (1998) Inhibition by ATP of hippocampal synaptic transmission requires localized extracellular catabolism by ecto-nucleotidases into adenosine and channeling to adenosine A(1) receptors. J Neurosci 18:1987-1995.
    • (1998) J Neurosci , vol.18 , pp. 1987-1995
    • Cunha, R.A.1    Sebastiao, A.M.2    Ribeiro, J.A.3
  • 8
    • 0030875738 scopus 로고    scopus 로고
    • Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus
    • Dunwiddie TV, Diao LH, Proctor WR (1997) Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus. J Neurosci 17:7673-7682.
    • (1997) J Neurosci , vol.17 , pp. 7673-7682
    • Dunwiddie, T.V.1    Diao, L.H.2    Proctor, W.R.3
  • 9
    • 0037008874 scopus 로고    scopus 로고
    • Cooperativity between extracellular adenosine 5′-triphosphate and activation of N-methyl-D-aspartate receptors in long-term potentiation induction in hippocampal CA1 neurons
    • Fujii S, Kato H, Kuroda Y (2002) Cooperativity between extracellular adenosine 5′-triphosphate and activation of N-methyl-D-aspartate receptors in long-term potentiation induction in hippocampal CA1 neurons. Neuroscience 113:617-628.
    • (2002) Neuroscience , vol.113 , pp. 617-628
    • Fujii, S.1    Kato, H.2    Kuroda, Y.3
  • 10
    • 0027165787 scopus 로고
    • A ligand binding study of the interactions of guanine nucleotides with non-NMDA receptors
    • Gorodinsky A, Paas Y, Teichberg VI (1993) A ligand binding study of the interactions of guanine nucleotides with non-NMDA receptors. Neurochem Int 23:285-291.
    • (1993) Neurochem Int , vol.23 , pp. 285-291
    • Gorodinsky, A.1    Paas, Y.2    Teichberg, V.I.3
  • 12
    • 0036241207 scopus 로고    scopus 로고
    • Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
    • Hardingham GE, Fukunaga J, Bading H (2002) Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat Neurosci 5:405-414.
    • (2002) Nat Neurosci , vol.5 , pp. 405-414
    • Hardingham, G.E.1    Fukunaga, J.2    Bading, H.3
  • 13
    • 0035287432 scopus 로고    scopus 로고
    • Glia: Listening and talking to the synapse
    • Haydon PG (2001) Glia: listening and talking to the synapse. Nat Rev Neurosci 2:185-193.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 185-193
    • Haydon, P.G.1
  • 15
    • 0034972413 scopus 로고    scopus 로고
    • Glutamate receptor subunit expression in primary neuronal and secondary glial cultures
    • Janssens N, Lesage ASJ (2001) Glutamate receptor subunit expression in primary neuronal and secondary glial cultures. J Neurochem 77:1457-1474.
    • (2001) J Neurochem , vol.77 , pp. 1457-1474
    • Janssens, N.1    Lesage, A.S.J.2
  • 16
    • 0035287474 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors and ATP signaling at synapses
    • Khakh BS (2001) Molecular physiology of P2X receptors and ATP signaling at synapses. Nat Rev Neurosci 2:165-174.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 165-174
    • Khakh, B.S.1
  • 17
    • 0031058152 scopus 로고    scopus 로고
    • ATP-gated cation channels (P2X purinoceptors) in trigeminal mesencephalic nucleus neurones of the rat
    • Khakh BS, Humphrey PPA, Henderson G (1997) ATP-gated cation channels (P2X purinoceptors) in trigeminal mesencephalic nucleus neurones of the rat. J Physiol (Lond) 498:709-715.
    • (1997) J Physiol (Lond) , vol.498 , pp. 709-715
    • Khakh, B.S.1    Humphrey, P.P.A.2    Henderson, G.3
  • 18
    • 0028118705 scopus 로고
    • Possible functional role of diadenosine polyphosphates: Negative feedback for excitation in the hippocampus
    • Klishin A, Lozovaya N, Pintor J, Miras-Portugal MT, Krishtal O (1994) Possible functional role of diadenosine polyphosphates: negative feedback for excitation in the hippocampus. Neuroscience 58:235-236.
    • (1994) Neuroscience , vol.58 , pp. 235-236
    • Klishin, A.1    Lozovaya, N.2    Pintor, J.3    Miras-Portugal, M.T.4    Krishtal, O.5
  • 19
    • 0028284469 scopus 로고
    • Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins
    • Kuryatov A, Laube B, Betz H, Kuhse J (1994) Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins. Neuron 12:1291-1300.
    • (1994) Neuron , vol.12 , pp. 1291-1300
    • Kuryatov, A.1    Laube, B.2    Betz, H.3    Kuhse, J.4
  • 20
    • 0028943569 scopus 로고
    • Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors
    • Laube B, Kuhse J, Rundström N, Kirsch J, Schmieden V, Betz H (1995) Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors. J Physiol (Lond) 483:613-619.
    • (1995) J Physiol (Lond) , vol.483 , pp. 613-619
    • Laube, B.1    Kuhse, J.2    Rundström, N.3    Kirsch, J.4    Schmieden, V.5    Betz, H.6
  • 21
    • 0030991790 scopus 로고    scopus 로고
    • Molecular determinants of agonist discrimination by NMDA receptor subunits: Analysis of the glutamate binding site on the NR2B subunit
    • Laube B, Hirai H, Sturgess M, Betz H, Kuhse J (1997) Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron 18:493-503.
    • (1997) Neuron , vol.18 , pp. 493-503
    • Laube, B.1    Hirai, H.2    Sturgess, M.3    Betz, H.4    Kuhse, J.5
  • 22
    • 0026601970 scopus 로고
    • NMDA channel behavior depends on agonist affinity
    • Lester RAJ, Jahr CE (1992) NMDA channel behavior depends on agonist affinity. J Neurosci 12:635-643.
    • (1992) J Neurosci , vol.12 , pp. 635-643
    • Lester, R.A.J.1    Jahr, C.E.2
  • 23
    • 0034033359 scopus 로고    scopus 로고
    • Novel mechanisms of inhibition by the P2 receptor agonist PPADS of ATP-activated current in dorsal root ganglion neurons
    • Li C (2000) Novel mechanisms of inhibition by the P2 receptor agonist PPADS of ATP-activated current in dorsal root ganglion neurons. J Neurophysiol 83:2533-2541.
    • (2000) J Neurophysiol , vol.83 , pp. 2533-2541
    • Li, C.1
  • 24
    • 0036483593 scopus 로고    scopus 로고
    • The structure and function of glutamate ion channels
    • Madden DR (2002) The structure and function of glutamate ion channels. Nat Neurosci Rev 3:91-101.
    • (2002) Nat Neurosci Rev , vol.3 , pp. 91-101
    • Madden, D.R.1
  • 26
    • 0034111166 scopus 로고    scopus 로고
    • ATP inhibits glutamate synaptic release by acting at P2Y receptors in pyramidal neurons of hippocampal slices
    • Mendoza-Fernandez V, Andrew RD, Barajas-Lopez C (2000) ATP inhibits glutamate synaptic release by acting at P2Y receptors in pyramidal neurons of hippocampal slices. J Pharmacol Exp Ther 293:172-179.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 172-179
    • Mendoza-Fernandez, V.1    Andrew, R.D.2    Barajas-Lopez, C.3
  • 27
    • 0023726324 scopus 로고
    • Effects of guanine nucleotides on N-methyl-D-aspartate receptor-ligand interactions
    • Monahan JB, Hood WF, Michel J, Compton RP (1988) Effects of guanine nucleotides on N-methyl-D-aspartate receptor-ligand interactions. Mol Pharmacol 34:111-116.
    • (1988) Mol Pharmacol , vol.34 , pp. 111-116
    • Monahan, J.B.1    Hood, W.F.2    Michel, J.3    Compton, R.P.4
  • 28
    • 0028810883 scopus 로고
    • Structure and function of the NMDA receptor channel
    • Mori H, Mishina M (1995) Structure and function of the NMDA receptor channel. Neuropharmacology 34:1219-1237.
    • (1995) Neuropharmacology , vol.34 , pp. 1219-1237
    • Mori, H.1    Mishina, M.2
  • 30
    • 0033755889 scopus 로고    scopus 로고
    • Neuronal P2X receptors: Localisation and functional properties
    • Nörenberg W, Illes P (2000) Neuronal P2X receptors: localisation and functional properties. Naunyn Schmiedebergs Arch Pharmacol 362:324-339.
    • (2000) Naunyn Schmiedebergs Arch Pharmacol , vol.362 , pp. 324-339
    • Nörenberg, W.1    Illes, P.2
  • 31
    • 0030760601 scopus 로고    scopus 로고
    • Effect of adenosine and some of its structural analogues on the conductance of NMDA receptor channels in a subset of striatal neurons
    • Nörenberg W, Wirkner K, Illes P (1997) Effect of adenosine and some of its structural analogues on the conductance of NMDA receptor channels in a subset of striatal neurons. Br J Pharmacol 122:71-80.
    • (1997) Br J Pharmacol , vol.122 , pp. 71-80
    • Nörenberg, W.1    Wirkner, K.2    Illes, P.3
  • 32
    • 0032032919 scopus 로고    scopus 로고
    • The macro- and microarchitecture of the ligand-binding domain of glutamate receptors
    • Paas Y (1998) The macro- and microarchitecture of the ligand-binding domain of glutamate receptors. Trends Neurosci 21:117-125.
    • (1998) Trends Neurosci , vol.21 , pp. 117-125
    • Paas, Y.1
  • 33
    • 0029927717 scopus 로고    scopus 로고
    • Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor
    • Paas Y, Devillers-Thiéry A, Changeux J-P, Medeville F, Teichberg VI (1996) Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor. EMBO J 15:1548-1556.
    • (1996) EMBO J , vol.15 , pp. 1548-1556
    • Paas, Y.1    Devillers-Thiéry, A.2    Changeux, J.-P.3    Medeville, F.4    Teichberg, V.I.5
  • 34
    • 0037101554 scopus 로고    scopus 로고
    • Ionotropic P2X purinoreceptors mediate synaptic transmission in rat pyramidal neurones of layer II/III of somato-sensory cortex
    • Pankratov Y, Lalo U, Krishtal O, Verkhratsky A (2002a) Ionotropic P2X purinoreceptors mediate synaptic transmission in rat pyramidal neurones of layer II/III of somato-sensory cortex. J Physiol (Lond) 542:529-536.
    • (2002) J Physiol (Lond) , vol.542 , pp. 529-536
    • Pankratov, Y.1    Lalo, U.2    Krishtal, O.3    Verkhratsky, A.4
  • 35
    • 0036813011 scopus 로고    scopus 로고
    • Role for P2X receptors in long-term potentiation
    • Pankratov YV, Lalo UV, Krishtal OA (2002b) Role for P2X receptors in long-term potentiation. J Neurosci 22:8363-8369.
    • (2002) J Neurosci , vol.22 , pp. 8363-8369
    • Pankratov, Y.V.1    Lalo, U.V.2    Krishtal, O.A.3
  • 36
    • 0031870349 scopus 로고    scopus 로고
    • Extracellular 3′,5′ cyclic guanosine monophosphate inhibits kainate-activated responses in cultured mouse cerebellar neurons
    • Poulopoulou C, Nowak LM (1998) Extracellular 3′,5′ cyclic guanosine monophosphate inhibits kainate-activated responses in cultured mouse cerebellar neurons. J Pharmacol Exp Ther 286:99-109.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 99-109
    • Poulopoulou, C.1    Nowak, L.M.2
  • 37
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V, Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50:413-492.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 38
    • 0032520191 scopus 로고    scopus 로고
    • Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture
    • Rao A, Kim E, Sheng M, Craig AM (1998) Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture. J Neurosci 18:1217-1229.
    • (1998) J Neurosci , vol.18 , pp. 1217-1229
    • Rao, A.1    Kim, E.2    Sheng, M.3    Craig, A.M.4
  • 40
    • 0028873054 scopus 로고
    • Calcium-dependent inactivation of synaptic NMDA receptors in hippocampal neurons
    • Rosenmund C, Feltz A, Westbrook GL (1995) Calcium-dependent inactivation of synaptic NMDA receptors in hippocampal neurons. J Neurophysiol 73:427-430.
    • (1995) J Neurophysiol , vol.73 , pp. 427-430
    • Rosenmund, C.1    Feltz, A.2    Westbrook, G.L.3
  • 41
    • 0031974820 scopus 로고    scopus 로고
    • Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices
    • Ross FM, Brodie MJ, Stone TW (1998) Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices. Br J Pharmacol 123:71-80.
    • (1998) Br J Pharmacol , vol.123 , pp. 71-80
    • Ross, F.M.1    Brodie, M.J.2    Stone, T.W.3
  • 42
    • 0025048136 scopus 로고
    • The P-loop - A common motif in ATP- and GTP-binding proteins
    • Saraste M, Sibbald PR, Wittinghofer A (1990) The P-loop - a common motif in ATP- and GTP-binding proteins. Trends Biochem Sci 15:430-434.
    • (1990) Trends Biochem Sci , vol.15 , pp. 430-434
    • Saraste, M.1    Sibbald, P.R.2    Wittinghofer, A.3
  • 44
    • 0035042633 scopus 로고    scopus 로고
    • Cloned P2X receptor subunits in cerebellum and hippocampus
    • Soto F, Rubio ME (2001) Cloned P2X receptor subunits in cerebellum and hippocampus. Drug Dev Res 52:133-139.
    • (2001) Drug Dev Res , vol.52 , pp. 133-139
    • Soto, F.1    Rubio, M.E.2
  • 46
    • 0033562610 scopus 로고    scopus 로고
    • The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro
    • Tovar KR, Westbrook GL (1999) The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro. J Neurosci 19:4180-4188.
    • (1999) J Neurosci , vol.19 , pp. 4180-4188
    • Tovar, K.R.1    Westbrook, G.L.2
  • 47
    • 0034844594 scopus 로고    scopus 로고
    • Multiple ecto-nucleotidases in PC12 cells: Identification and cellular distribution after heterologous expression
    • Vollmayer P, Koch M, Braun N, Heine P, Servos J, Israr E, Kegel B, Zimmermann H (2001) Multiple ecto-nucleotidases in PC12 cells: identification and cellular distribution after heterologous expression. J Neurochem 78:1019-1028.
    • (2001) J Neurochem , vol.78 , pp. 1019-1028
    • Vollmayer, P.1    Koch, M.2    Braun, N.3    Heine, P.4    Servos, J.5    Israr, E.6    Kegel, B.7    Zimmermann, H.8
  • 48
    • 0024339711 scopus 로고
    • ATP-induced synaptic potentiation in hippocampal slices
    • Wieraszko A, Seyfried TN (1989) ATP-induced synaptic potentiation in hippocampal slices. Brain Res 491:356-359.
    • (1989) Brain Res , vol.491 , pp. 356-359
    • Wieraszko, A.1    Seyfried, T.N.2
  • 49
    • 0027525324 scopus 로고
    • Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors
    • Williams K (1993) Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol 44:851-859.
    • (1993) Mol Pharmacol , vol.44 , pp. 851-859
    • Williams, K.1
  • 51
    • 0033970312 scopus 로고    scopus 로고
    • Subunit-dependent inhibition of recombinant rodent N-methyl-D-aspartate receptors by HIV-1 glycoprotein 120 derived peptide
    • Wittekindt B, Betz H, Laube B (2000) Subunit-dependent inhibition of recombinant rodent N-methyl-D-aspartate receptors by HIV-1 glycoprotein 120 derived peptide. Neurosci Lett 280:151-154.
    • (2000) Neurosci Lett , vol.280 , pp. 151-154
    • Wittekindt, B.1    Betz, H.2    Laube, B.3
  • 52
    • 0034798601 scopus 로고    scopus 로고
    • Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as a major site of Conantokin-G inhibition
    • Wittekindt B, Malany S, Schemm R, Otvos L, Maccechini M-L, Laube B, Betz H (2001) Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as a major site of Conantokin-G inhibition. Neuropharmacology 41:753-761.
    • (2001) Neuropharmacology , vol.41 , pp. 753-761
    • Wittekindt, B.1    Malany, S.2    Schemm, R.3    Otvos, L.4    Maccechini, M.-L.5    Laube, B.6    Betz, H.7
  • 53
    • 0034666044 scopus 로고    scopus 로고
    • Single channel properties of P2X ATP receptors in outside-out patches from rat hippocampal granule cells
    • Wong AYC, Burnstock G, Gibb AJ (2000) Single channel properties of P2X ATP receptors in outside-out patches from rat hippocampal granule cells. J Physiol (Lond) 527:529-547.
    • (2000) J Physiol (Lond) , vol.527 , pp. 529-547
    • Wong, A.Y.C.1    Burnstock, G.2    Gibb, A.J.3
  • 54
    • 0028041238 scopus 로고
    • Signaling via ATP in the nervous system
    • Zimmermann H (1994) Signaling via ATP in the nervous system. Trends Neurosci 17:420-426.
    • (1994) Trends Neurosci , vol.17 , pp. 420-426
    • Zimmermann, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.