메뉴 건너뛰기




Volumn 63, Issue 5, 2003, Pages 1032-1042

Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ALCOHOL; FATTY ALCOHOL PHOSPHATE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; HYDROCARBON; LYSOPHOSPHATIDIC ACID RECEPTOR; MEMBRANE RECEPTOR; PHOSPHATE; RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

EID: 0038069067     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.63.5.1032     Document Type: Article
Times cited : (72)

References (39)
  • 1
    • 0031723635 scopus 로고    scopus 로고
    • Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization
    • An S, Bleu T, Zheng Y, and Goetzl EJ (1998) Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization. Mol Pharmacol 54:881-888.
    • (1998) Mol Pharmacol , vol.54 , pp. 881-888
    • An, S.1    Bleu, T.2    Zheng, Y.3    Goetzl, E.J.4
  • 2
    • 0034726004 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species. Structure-activity relationship of cloned LPA receptors
    • Bandoh K, Aoki J, Taira A, Tsujimoto M, Arai H, and Inoue K (2000) Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species. Structure-activity relationship of cloned LPA receptors. FEBS Lett 478:159-165.
    • (2000) FEBS Lett , vol.478 , pp. 159-165
    • Bandoh, K.1    Aoki, J.2    Taira, A.3    Tsujimoto, M.4    Arai, H.5    Inoue, K.6
  • 3
    • 0029936609 scopus 로고    scopus 로고
    • Inhibitors of lipid phosphatidate receptors: N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids
    • Bittman R, Swords B, Liliom K, and Tigyi G (1996) Inhibitors of lipid phosphatidate receptors: N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids. J Lipid Res 37:391-398.
    • (1996) J Lipid Res , vol.37 , pp. 391-398
    • Bittman, R.1    Swords, B.2    Liliom, K.3    Tigyi, G.4
  • 4
    • 0029130345 scopus 로고
    • Lipid signaling enzymes and surface dilution kinetics
    • Carman GM, Deems RA, and Dennis EA (1995) Lipid signaling enzymes and surface dilution kinetics. J Biol Chem 270:18711-18714.
    • (1995) J Biol Chem , vol.270 , pp. 18711-18714
    • Carman, G.M.1    Deems, R.A.2    Dennis, E.A.3
  • 5
    • 0030890019 scopus 로고    scopus 로고
    • Differential inhibition of lysophosphatidate signaling by volatile anesthetics
    • Chan CK and Durieux ME (1997) Differential inhibition of lysophosphatidate signaling by volatile anesthetics. Anesthesiology 86:660-669.
    • (1997) Anesthesiology , vol.86 , pp. 660-669
    • Chan, C.K.1    Durieux, M.E.2
  • 6
    • 0035527674 scopus 로고    scopus 로고
    • The Power Issue: Determination of KB or Ki from IC50. A closer look at the Cheng-Prusoff equation, the Schield plot and related power equations
    • Cheng HC (2002) The power issue: determination of KB or Ki from IC50. A closer look at the Cheng-Prusoff equation, the Schield plot and related power equations. J Pharmacol Toxicol Methods 46:61-71.
    • (2002) J Pharmacol Toxicol Methods , vol.46 , pp. 61-71
    • Cheng, H.C.1
  • 8
    • 0033669622 scopus 로고    scopus 로고
    • Lysophosphatidic acid receptors
    • Contos JJ, Ishii I, and Chun J (2000) Lysophosphatidic acid receptors. Mol Pharmacol 58:1188-1196.
    • (2000) Mol Pharmacol , vol.58 , pp. 1188-1196
    • Contos, J.J.1    Ishii, I.2    Chun, J.3
  • 9
    • 0036308503 scopus 로고    scopus 로고
    • Lysophosphatidic acid protects and rescues intestinal epithelial cells from radiation- and chemotherapy-induced apoptosis
    • Deng W, Balazs L, Wang D-A, Van Middlesworth L, Tigyi G, and Johnson LR (2002) Lysophosphatidic acid protects and rescues intestinal epithelial cells from radiation- and chemotherapy-induced apoptosis. Gastroenterology 123:206-216.
    • (2002) Gastroenterology , vol.123 , pp. 206-216
    • Deng, W.1    Balazs, L.2    Wang, D.-A.3    Van Middlesworth, L.4    Tigyi, G.5    Johnson, L.R.6
  • 15
    • 0029857994 scopus 로고    scopus 로고
    • Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes
    • Guo Z, Liliom K, Fischer DJ, Bathurst IC, Tomei LD, Kiefer MC, and Tigyi G (1996) Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes. Proc Natl Acad Sci USA 93:14367-14372.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14367-14372
    • Guo, Z.1    Liliom, K.2    Fischer, D.J.3    Bathurst, I.C.4    Tomei, L.D.5    Kiefer, M.C.6    Tigyi, G.7
  • 16
    • 0037571112 scopus 로고    scopus 로고
    • Merck molecular force field. I. Basis form scope parameterization and performance of MMFF94*
    • Halgren TA (1996) Merck molecular force field. I. Basis form scope parameterization and performance of MMFF94*. J Comput Chem 17:490-519.
    • (1996) J Comput Chem , vol.17 , pp. 490-519
    • Halgren, T.A.1
  • 17
    • 0035206909 scopus 로고    scopus 로고
    • Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: Discovery of a LPA1/LPA3 receptor antagonist
    • Heise CE, Santos WL, Schreihofer AM, Heasley BH, Mukhin YV, Macdonald TL, and Lynch KR (2001) Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: discovery of a LPA1/LPA3 receptor antagonist. Mol Pharmacol 60:1173-1180.
    • (2001) Mol Pharmacol , vol.60 , pp. 1173-1180
    • Heise, C.E.1    Santos, W.L.2    Schreihofer, A.M.3    Heasley, B.H.4    Mukhin, Y.V.5    Macdonald, T.L.6    Lynch, K.R.7
  • 21
    • 0029832759 scopus 로고    scopus 로고
    • N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors
    • Liliom K, Bittman R, Swords B, and Tigyi G (1996a) N-Palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors. Mol Pharmacol 50:616-623.
    • (1996) Mol Pharmacol , vol.50 , pp. 616-623
    • Liliom, K.1    Bittman, R.2    Swords, B.3    Tigyi, G.4
  • 24
    • 0037162084 scopus 로고    scopus 로고
    • Structure-activity relationships of lysophosphatidic acid analogs
    • Lynch KR and Macdonald TL (2002) Structure-activity relationships of lysophosphatidic acid analogs. Biochim Biophys Acta 1582:289-294.
    • (2002) Biochim Biophys Acta , vol.1582 , pp. 289-294
    • Lynch, K.R.1    Macdonald, T.L.2
  • 26
    • 0030203710 scopus 로고    scopus 로고
    • Distributed automated docking of flexible ligands to proteins: Parallel applications of AutoDock 2.4
    • Morris GM, Goodsell DS, Huey R, and Olson AJ (1996) Distributed automated docking of flexible ligands to proteins: Parallel applications of AutoDock 2.4. J Comput-Aided Mol Des 10:293-304.
    • (1996) J Comput-Aided Mol Des , vol.10 , pp. 293-304
    • Morris, G.M.1    Goodsell, D.S.2    Huey, R.3    Olson, A.J.4
  • 30
    • 0033536049 scopus 로고    scopus 로고
    • Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions
    • Siess W, Zangl KJ, Essler M, Bauer M, Brandl R, Corrinth C, Bittman R, Tigyi G and Aepfelbacher M (1999) Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions. Proc Natl Acad Sci USA 96:6931-6936.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 6931-6936
    • Siess, W.1    Zangl, K.J.2    Essler, M.3    Bauer, M.4    Brandl, R.5    Corrinth, C.6    Bittman, R.7    Tigyi, G.8    Aepfelbacher, M.9
  • 31
    • 0028340689 scopus 로고
    • Biochemical characterization of the interaction of lipid phosphoric acids with human platelets: Comparison with platelet activating factor
    • Sugiura T, Tokumura A, Gregory L, Nouchi T, Weintraub ST, and Hanahan DJ (1994) Biochemical characterization of the interaction of lipid phosphoric acids with human platelets: comparison with platelet activating factor. Arch Biochem Biophys 311:358-368.
    • (1994) Arch Biochem Biophys , vol.311 , pp. 358-368
    • Sugiura, T.1    Tokumura, A.2    Gregory, L.3    Nouchi, T.4    Weintraub, S.T.5    Hanahan, D.J.6
  • 32
    • 0035025354 scopus 로고    scopus 로고
    • Physiological responses to lysophosphatidic acid and related glycero-phospholipids
    • Tigyi G (2001) Physiological responses to lysophosphatidic acid and related glycero-phospholipids. Prostaglandins Other Lipid Mediat 64:47-62.
    • (2001) Prostaglandins Other Lipid Mediat , vol.64 , pp. 47-62
    • Tigyi, G.1
  • 33
    • 0002531510 scopus 로고    scopus 로고
    • Phospholipid growth factors: Identification and mechanism of action
    • Laychock SG and Rubin RP eds, CRC Press, Boca Raton, FL
    • Tigyi G, Liliom K, Fischer DJ, and Guo Z (1999) Phospholipid growth factors: identification and mechanism of action, in Lipid second messengers (Laychock SG and Rubin RP eds) pp 51-81, CRC Press, Boca Raton, FL.
    • (1999) Lipid Second Messengers , pp. 51-81
    • Tigyi, G.1    Liliom, K.2    Fischer, D.J.3    Guo, Z.4
  • 34
    • 0031022002 scopus 로고    scopus 로고
    • Local anesthetics inhibit receptors coupled to phosphoinositide signaling in Xenopus oocytes
    • Tigyi J, Tigyi G, Liliom K, and Miledi R (1997) Local anesthetics inhibit receptors coupled to phosphoinositide signaling in Xenopus oocytes. Pflueg Arch Eur J Physiol 433:478-487.
    • (1997) Pflueg Arch Eur J Physiol , vol.433 , pp. 478-487
    • Tigyi, J.1    Tigyi, G.2    Liliom, K.3    Miledi, R.4
  • 37
    • 0035966064 scopus 로고    scopus 로고
    • A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors
    • Wang DA, Lorincz Z, Bautista DL, Liliom K, Tigyi G, and Parrill AL (2001) A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors. J Biol Chem 276:49213-49220.
    • (2001) J Biol Chem , vol.276 , pp. 49213-49220
    • Wang, D.A.1    Lorincz, Z.2    Bautista, D.L.3    Liliom, K.4    Tigyi, G.5    Parrill, A.L.6
  • 39
    • 0033521861 scopus 로고    scopus 로고
    • Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate
    • Zhang G, Contos JJ, Weiner JA, Fukushima N, and Chun J (1999) Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. Gene 227:89-99.
    • (1999) Gene , vol.227 , pp. 89-99
    • Zhang, G.1    Contos, J.J.2    Weiner, J.A.3    Fukushima, N.4    Chun, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.