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Volumn 10, Issue 2, 2003, Pages 65-72

An attempt to modulate the microporous diffusion of a model polypeptide by altering its secondary structure

Author keywords

Aqueous Pore Diffusion; Conantokin G; Membrane Transport; Secondary Conformations

Indexed keywords

CALCIUM; CALCIUM ION; CONANTOKIN G; ENZYME; POLYPEPTIDE;

EID: 0038025877     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/713840357     Document Type: Article
Times cited : (1)

References (38)
  • 1
    • 0029938238 scopus 로고    scopus 로고
    • Vaginal permeability and enzymatic activity studies in normal and ovariectomized rabbits
    • Acaturk, F., and Robinson, J. R. 1996. Vaginal permeability and enzymatic activity studies in normal and ovariectomized rabbits. Pharm. Res. 13:779-783.
    • (1996) Pharm. Res. , vol.13 , pp. 779-783
    • Acaturk, F.1    Robinson, J.R.2
  • 2
    • 0024371793 scopus 로고
    • Comparison of the effects of various transmucosal absorption promoters on buccal insulin delivery
    • Aungst, B. J., and Rogers, N. J. 1989. Comparison of the effects of various transmucosal absorption promoters on buccal insulin delivery. Int. J. Pharm. 53:227-234.
    • (1989) Int. J. Pharm. , vol.53 , pp. 227-234
    • Aungst, B.J.1    Rogers, N.J.2
  • 3
    • 0026758261 scopus 로고
    • Structural specificity of mucosal-cell transport and metabolism of peptide drugs: Implication for oral peptide drug delivery
    • Bai, J. P., and Amidon. G. L. 1992. Structural specificity of mucosal-cell transport and metabolism of peptide drugs: Implication for oral peptide drug delivery. Pharm. Res. 9:969-978.
    • (1992) Pharm. Res. , vol.9 , pp. 969-978
    • Bai, J.P.1    Amidon, G.L.2
  • 6
    • 0031469378 scopus 로고    scopus 로고
    • Metal-ion binding properties of synthetic conantokin-G
    • Blandl, T., Zajicek, J., Prorok, M., and Castellino, F. J. 1997. Metal-ion binding properties of synthetic conantokin-G. Biochem. J. 328:777-783.
    • (1997) Biochem. J. , vol.328 , pp. 777-783
    • Blandl, T.1    Zajicek, J.2    Prorok, M.3    Castellino, F.J.4
  • 7
    • 0015522150 scopus 로고
    • Determination of the secondary structures of proteins By CD and optical rotatory dispersion
    • Chen, Y. H., Yans, Y., and Martinez, H. M. 1972. Determination of the secondary structures of proteins By CD and optical rotatory dispersion. Biochemistry 11:4120-4131.
    • (1972) Biochemistry , vol.11 , pp. 4120-4131
    • Chen, Y.H.1    Yans, Y.2    Martinez, H.M.3
  • 8
    • 0024138140 scopus 로고
    • Hindered diffusion of water-soluble macromolecules in membranes
    • Davidson, M. G., and Deen, W. M. 1988. Hindered diffusion of water-soluble macromolecules in membranes. Macromolecules 21:3474-3481.
    • (1988) Macromolecules , vol.21 , pp. 3474-3481
    • Davidson, M.G.1    Deen, W.M.2
  • 10
    • 0026672148 scopus 로고
    • Transport of thyrotropin releasing hormone in rabbit buccal mucosa in vitro
    • Dowty, M. E., Knuth, K. E., Irons, B. K., and Robinson, J. R. 1992. Transport of thyrotropin releasing hormone in rabbit buccal mucosa in vitro. Pharm. Res. 9:1113-1122.
    • (1992) Pharm. Res. , vol.9 , pp. 1113-1122
    • Dowty, M.E.1    Knuth, K.E.2    Irons, B.K.3    Robinson, J.R.4
  • 11
    • 0030056114 scopus 로고    scopus 로고
    • Identification of the phospholipid binding in the vitamin K-dependent blood coagulation protein factor IX
    • Freedman, S. J., Blostein, M. D., Baleja, J. D., Jacobs, M., Furie, B. C., and Furie, B. 1996. Identification of the phospholipid binding in the vitamin K-dependent blood coagulation protein factor IX. J. Biol. Chem. 271:16227-16236.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16227-16236
    • Freedman, S.J.1    Blostein, M.D.2    Baleja, J.D.3    Jacobs, M.4    Furie, B.C.5    Furie, B.6
  • 12
    • 0030480443 scopus 로고    scopus 로고
    • The effect of conformation on membrane permeability of an acyloxyalkoxy-linked cyclic prodrug of a model hexapeptide
    • Gangawar, S., Jois, S. D., Siahaan, T. J., Vander Velde, D. G., Stella, V. J., and Borchardt, R. T. 1996. The effect of conformation on membrane permeability of an acyloxyalkoxy-linked cyclic prodrug of a model hexapeptide. Pharm. Res. 13:1657-1662.
    • (1996) Pharm. Res. , vol.13 , pp. 1657-1662
    • Gangawar, S.1    Jois, S.D.2    Siahaan, T.J.3    Vander Velde, D.G.4    Stella, V.J.5    Borchardt, R.T.6
  • 13
    • 0033067843 scopus 로고    scopus 로고
    • The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides
    • Gudmundsson, G. S., Jois, S. D., Vander Velde, D. G., Siahaan, T. J., Wang, B., and Borchardt, R. T. 1999. The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides. J. Pept. Res. 53:383-392.
    • (1999) J. Pept. Res. , vol.53 , pp. 383-392
    • Gudmundsson, G.S.1    Jois, S.D.2    Vander Velde, D.G.3    Siahaan, T.J.4    Wang, B.5    Borchardt, R.T.6
  • 14
    • 0000003163 scopus 로고
    • Diffusion of large flexible polymer chains through model porous membranes
    • Guillot, G., Léger, L., and Rondelez, F. 1985. Diffusion of large flexible polymer chains through model porous membranes. Macromolecules 18:2531-2537.
    • (1985) Macromolecules , vol.18 , pp. 2531-2537
    • Guillot, G.1    Léger, L.2    Rondelez, F.3
  • 15
    • 0023988250 scopus 로고
    • Effects of concentration and volume on nasal bioavailability and biological response to desmopressin
    • Harris, A. S., Ohlin, M., Lethagen, S., and Nilsson, I. M. 1988. Effects of concentration and volume on nasal bioavailability and biological response to desmopressin. J. Pharm. Sci. 77:337-339.
    • (1988) J. Pharm. Sci. , vol.77 , pp. 337-339
    • Harris, A.S.1    Ohlin, M.2    Lethagen, S.3    Nilsson, I.M.4
  • 16
    • 0031958251 scopus 로고    scopus 로고
    • Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-Peptides
    • He, Y.-L., Murby, S., Warhurst, G., Gifford, L., Walker, D., Ayrton, J., Eastmond, R., and Rowland, M. 1998. Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-Peptides. J. Pharm. Sci. 87:626-633.
    • (1998) J. Pharm. Sci. , vol.87 , pp. 626-633
    • He, Y.-L.1    Murby, S.2    Warhurst, G.3    Gifford, L.4    Walker, D.5    Ayrton, J.6    Eastmond, R.7    Rowland, M.8
  • 17
    • 0034605695 scopus 로고    scopus 로고
    • Permeability of antisense oligonucleotide through porcine buccal mucosa
    • Jasti, B. R., Zhou, S., Mehta, R. C., and Li, X. 2000. Permeability of antisense oligonucleotide through porcine buccal mucosa. Int. J. Pharm. 208:35-39.
    • (2000) Int. J. Pharm. , vol.208 , pp. 35-39
    • Jasti, B.R.1    Zhou, S.2    Mehta, R.C.3    Li, X.4
  • 18
    • 0031916032 scopus 로고    scopus 로고
    • Permeation of unfolded basic fibroblast growth factor (bFGF) across rabbit buccal mucosa - Does unfolding of bFGF enhance transport?
    • Johnston, T. P., Rahman, A., Alur, H. H., Shah, D., and Mitra, A. K. 1997. Permeation of unfolded basic fibroblast growth factor (bFGF) across rabbit buccal mucosa - Does unfolding of bFGF enhance transport? Pharm. Res. 15:246-253.
    • (1997) Pharm. Res. , vol.15 , pp. 246-253
    • Johnston, T.P.1    Rahman, A.2    Alur, H.H.3    Shah, D.4    Mitra, A.K.5
  • 19
    • 0030931449 scopus 로고    scopus 로고
    • Paracellular diffusion in caco-2 cell monolayers: Effect of perturbation on the transport of hydrophilic compounds that vary in charge and size
    • Knipp, G. T., Ho, N. F. H., Barsuhn, C. L., and Borchardt, R. T. 1997. Paracellular diffusion in caco-2 cell monolayers: Effect of perturbation on the transport of hydrophilic compounds that vary in charge and size. J. Pharm. Sci. 86:1105-1110.
    • (1997) J. Pharm. Sci. , vol.86 , pp. 1105-1110
    • Knipp, G.T.1    Ho, N.F.H.2    Barsuhn, C.L.3    Borchardt, R.T.4
  • 21
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski, C. A., Lombardo, F., Dominy, B. W., and Feeney, P. J. 2001. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 46:3-26.
    • (2001) Adv. Drug Deliv. Rev. , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 22
  • 23
    • 0004135189 scopus 로고
    • Philadelphia: Lea & Febiger
    • Martin, A. 1993. Physical Pharmacy. Philadelphia: Lea & Febiger, 212-250.
    • (1993) Physical Pharmacy , pp. 212-250
    • Martin, A.1
  • 26
    • 0030792730 scopus 로고    scopus 로고
    • Estimation of the relative contribution of the transcellular and paracellular pathway to the transport of passively absorbed drugs in the caco-2 cell culture model
    • Pade, V., and Stavchansky, S. 1997. Estimation of the relative contribution of the transcellular and paracellular pathway to the transport of passively absorbed drugs in the caco-2 cell culture model. Pharm. Res. 14:1210-1215.
    • (1997) Pharm. Res. , vol.14 , pp. 1210-1215
    • Pade, V.1    Stavchansky, S.2
  • 27
    • 0023521841 scopus 로고
    • Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat
    • Pappenheimer, J. R., and Reiss, K. Z. 1987. Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat. J. Membr Biol. 100: 123-136.
    • (1987) J. Membr. Biol. , vol.100 , pp. 123-136
    • Pappenheimer, J.R.1    Reiss, K.Z.2
  • 29
    • 0030979950 scopus 로고    scopus 로고
    • Absorption and excretion of undegradable peptides: Role of lipid solubility and net charge
    • Pappenheimer, J. R., Karnovsky, M. L., and Maggio, J. E. 1997. Absorption and excretion of undegradable peptides: Role of lipid solubility and net charge. J. Pharm. Exp. Ther 280:292-300.
    • (1997) J. Pharm. Exp. Ther. , vol.280 , pp. 292-300
    • Pappenheimer, J.R.1    Karnovsky, M.L.2    Maggio, J.E.3
  • 30
    • 0030903756 scopus 로고    scopus 로고
    • Effect of size and charge on the passive diffusion of peptides across caco-2 cell monolayers via the paracellular pathway
    • Pauletti, G. M., Okumu, F. W., and Borchardt, R. T. 1997. Effect of size and charge on the passive diffusion of peptides across caco-2 cell monolayers via the paracellular pathway. Pharm. Res. 14:164-171.
    • (1997) Pharm. Res. , vol.14 , pp. 164-171
    • Pauletti, G.M.1    Okumu, F.W.2    Borchardt, R.T.3
  • 31
    • 0030449042 scopus 로고    scopus 로고
    • Calcium binding properties of synthetic γ-carboxyglutamic acid containing marine snail "Sleeper" peptides, conantokin G and conantokin T
    • Prorok, M., Warder, S. E., Blandl, T., and Castellino, F. J. 1996. Calcium binding properties of synthetic γ-carboxyglutamic acid containing marine snail "Sleeper" peptides, conantokin G and conantokin T. Biochemistry 35:16528-16534.
    • (1996) Biochemistry , vol.35 , pp. 16528-16534
    • Prorok, M.1    Warder, S.E.2    Blandl, T.3    Castellino, F.J.4
  • 32
    • 0030994212 scopus 로고    scopus 로고
    • Three dimensional structure of a γ-carboxyglutamic acid-containing conantoxine, conantokin G, from the marine snail conus geographus: The metal-free conformer
    • Rigby, A. C., Buleja, J. D., Furie, B. C., and Furie, B. 1997a. Three dimensional structure of a γ-carboxyglutamic acid-containing conantoxine, conantokin G, from the marine snail conus geographus: The metal-free conformer. Biochemistry 36:6906-6914.
    • (1997) Biochemistry , vol.36 , pp. 6906-6914
    • Rigby, A.C.1    Buleja, J.D.2    Furie, B.C.3    Furie, B.4
  • 33
    • 0031456675 scopus 로고    scopus 로고
    • Role of γ-carboxyglutamic acid in the calcium-induced structural transition of conantokin G, a conantoxin from the marine snail conus geographus
    • Rigby, A. C., Baleja, J. D., Li, L., Pederison, L. G., Furie, B. C., and Furie, B. 1997b. Role of γ-carboxyglutamic acid in the calcium-induced structural transition of conantokin G, a conantoxin from the marine snail conus geographus. Biochemistry 36:15677-15684.
    • (1997) Biochemistry , vol.36 , pp. 15677-15684
    • Rigby, A.C.1    Baleja, J.D.2    Li, L.3    Pederison, L.G.4    Furie, B.C.5    Furie, B.6
  • 34
    • 0029757133 scopus 로고    scopus 로고
    • Systemic delivery of peptides and proteins across absorptive mucosae
    • Sayani, A. P., and Chien, Y. W. 1996. Systemic delivery of peptides and proteins across absorptive mucosae. Crit. Rev. Ther. Drug Carrier Syst. 13:85-184.
    • (1996) Crit. Rev. Ther. Drug Carrier Syst. , vol.13 , pp. 85-184
    • Sayani, A.P.1    Chien, Y.W.2
  • 35
    • 0031035377 scopus 로고    scopus 로고
    • Determination of the solution structure of conantokin G and conantokin T by CD and NMR spectroscopy
    • Skjaerbeak, N., Nielson, K. J., Lewis, R. J., Alewood, P., and Crail, D. J. 1997. Determination of the solution structure of conantokin G and conantokin T by CD and NMR spectroscopy. J. Biol. Chem. 272:2291-2299.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2291-2299
    • Skjaerbeak, N.1    Nielson, K.J.2    Lewis, R.J.3    Alewood, P.4    Crail, D.J.5
  • 37
    • 0029780681 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of recombinant human granulocyte colony-stimulating factor (rhGCSF) after administration of a rectal dosage vehicle
    • Watanabe, Y., Kiriyama, M., Ito, R., Kikychi, R., Mizufune, Y., Nomura, H., Miyazaki,M., and Matsumoto, M. 1996. Pharmacodynamics and pharmacokinetics of recombinant human granulocyte colony-stimulating factor (rhGCSF) after administration of a rectal dosage vehicle. Biol. Pharm. Bull. 19:1059-1063.
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 1059-1063
    • Watanabe, Y.1    Kiriyama, M.2    Ito, R.3    Kikychi, R.4    Mizufune, Y.5    Nomura, H.6    Miyazaki, M.7    Matsumoto, M.8
  • 38
    • 0032853619 scopus 로고    scopus 로고
    • Intestinal peptide transport systems and oral drug availability
    • Yang, C. Y., Dantzig, A. H., and Pidgeon, C. 1999. Intestinal peptide transport systems and oral drug availability. Pharm. Res. 16:1331-1343.
    • (1999) Pharm. Res. , vol.16 , pp. 1331-1343
    • Yang, C.Y.1    Dantzig, A.H.2    Pidgeon, C.3


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