Permeation of unfolded basic fibroblast growth factor (bFGF) across rabbit buccal mucosa - Does unfolding of bFGF enhance transport?

Pharmaceutical Research

Volumn 15, Issue 2, 1998, Pages 246-253

  Johnston, Thomas P ^a   Rahman, Atiq ^b   Alur, Hemant ^b   Shah, Dipesh ^b   Mitra, Ashim K ^b  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b NONE

Author keywords

Basic fibroblast growth factor; Buccal delivery; Denaturation; Protein unfolding; Rabbit; Transmucosal permeation

Indexed keywords

GLYCOCHOLATE SODIUM; RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR;

ANIMAL TISSUE; ARTICLE; DIALYSIS; DRUG DELIVERY SYSTEM; MALE; MEMBRANE PERMEABILITY; MOUTH MUCOSA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN TRANSPORT; RABBIT;

ANIMALS; CHEEK; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFUSION; FIBROBLAST GROWTH FACTOR 2; HUMANS; HYDROLYSIS; MALE; MOUTH MUCOSA; PROTEIN FOLDING; RABBITS; SERINE ENDOPEPTIDASES; SPECTROMETRY, FLUORESCENCE;

EID: 0031916032     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011966602179     Document Type: Article

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