NF-κB in epiretinal membranes after human diabetic retinopathy

Diabetologia

Volumn 46, Issue 5, 2003, Pages 699-703

  Mitamura, Y ^a,b   Harada, T ^c,f   Harada, C ^c,d   Ohtsuka, K ^b   Kotake, S ^d   Ohno, S ^d   Tanaka, K ^e   Takeuchi, S ^a   Wada, K ^c  

^a TOHO UNIVERSITY SAKURA MEDICAL CENTER   (Japan)

^b SAPPORO MEDICAL UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^d HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Epiretinal membrane; Interleukin 8; NF B; Proliferative diabetic retinopathy; Vascular endothelial cell; Von Willebrand factor

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; VON WILLEBRAND FACTOR; MESSENGER RNA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC RETINOPATHY; ENDOTHELIUM CELL; EPIRETINAL MEMBRANE; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VISUAL IMPAIRMENT; VITRECTOMY; AGED; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; RETINA; VASCULAR ENDOTHELIUM;

ADULT; AGED; DIABETIC RETINOPATHY; ENDOTHELIUM, VASCULAR; EPIRETINAL MEMBRANE; GENE EXPRESSION REGULATION; HUMANS; MIDDLE AGED; NF-KAPPA B; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0038015073     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-003-1084-x     Document Type: Article

References (40)

1. Margherio RR, Margherio AR (2000) Epiretinal macular membranes. In: Albert DM, Jakobiec FA, Azar DT, Gragoudas ES (eds) Principles and practice of ophthalmology, 2nd edn. W.B. Saunders, Philadelphia, p 2103
2. Klein R, Klein BE, Moss SE, Davis MD, DeMets DL (1984) The Wisconsin epidemiologic study of diabetic retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol 102:520-526
3. Klein R, Klein BE, Moss SE, Davis MD, DeMets DL (1984) The Wisconsin epidemiologic study of diabetic retinopathy. III. Prevalence and risk of diabetic retinopathy when age at diagnosis is 30 or more years. Arch Ophthalmol 102:527-532
4. Roth AM, Foos RY (1971) Surface wrinkling retinopathy in eyes enucleated at autopsy. Trans Am Acad Ophthalmol Otolaryngol 75:1047-1058
5. Bellhorn MB, Friedman AH, Wise GN, Henkind P (1975) Ultrastructure and clinicopathologic correlation of idiopathic preretinal macular fibrosis. Am J Ophthalmol 79:366-373
6. McLeod D, Hiscott PS, Grierson I (1987) Age-related cellular proliferation at the vitreoretinal juncture. Eye 1:263-281
7. Smiddy WE, Maguire AM, Green WR et al. (1989) Idiopathic epiretinal membranes. Ultrastructural characteristics and clinicopathologic correlation. Ophthalmology 96:811-821
8. Sivalingam A, Kenney J, Brown GC, Benson WE, Donoso L (1990) Basic fibroblast growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol 108:869-872
9. Wiedemann P (1992) Growth factors in retinal diseases: proliferative vitreoretinopathy, proliferative diabetic retinopathy, and retinal degeneration. Surv Ophthalmol 36:373-384
10. Aiello LP, Avery RL, Arrigg PG et al (1994) Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 331:1480-1487
11. Elner SG, Elner VM, Jaffe GJ, Stuart A, Kunkel SL, Strieter RM (1995) Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy. Curr Eye Res 14:1045-1053
12. Hueber A, Wiedemann P, Esser P, Heimann K (1996) Basic fibroblast growth factor mRNA, bFGF peptide and FGF receptor in epiretinal membranes of intraocular proliferative disorders (PVR and PDR). Int Ophthalmol 20:345-350
13. Harada T, Harada C, Mitamura Y et al. (2002) Neurotrophic factor receptors in epiretinal membranes after human diabetic retinopathy. Diabetes Care 25:1060-1065
14. Baeuerle PA, Henkel T (1994) Function and activation of NF-κB in the immune system. Annu Rev Immunol 12:141-179
15. Wang X, Jobin C, Allen JB, Roberts WL, Jaffe GJ (1999) Suppression of NF-κB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor. Invest Ophthalmol Vis Sci 40:477-486
16. Ghosh S, Karin M (2002) Missing pieces in the NF-κB puzzle. Cell 109 Suppl:S81-96
17. Grilli M, Chiu JJ, Lenardo MJ (1993) NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int Rev Cytol 143:1-62
18. Stoltz RA, Abraham NG, Laniado-Schwartzman M (1996) The role of NF-κB in the angiogenic response of coronary microvessel endothelial cells. Proc Natl Acad Sci USA 93:2832-2837
19. Yoshida A, Yoshida S, Hata Y, Khalil AK, Ishibashi T, Inomata H (1998) The role of NF-κB in retinal neovascularization in the rat. Possible involvement of cytokine-induced neutrophil chemoattractant (CINC), a member of the interleukin-8 family. J Histochem Cytochem 46:429-436
20. Yoshida A, Yoshida S, Khalil AK, Ishibashi T, Inomata H (1998) Role of NF-κB-mediated interleukin-8 expression in intraocular neovascularization. Invest Ophthalmol Vis Sci 39:1097-1106
21. Harada T, Harada C, Sekiguchi M, Wada K (1998) Light-induced retinal degeneration suppresses developmental progression of flip-to-flop alternative splicing in GluR1. J Neurosci 18:3336-3343
22. Hammes HP, Hoerauf H, Alt A et al. (1999) N(epsilon) (carboxymethyl)lysin and the AGE receptor RAGE colocalize in age-related macular degeneration. Invest Ophthalmol Vis Sci 40:1855-1859
23. Wagner DD (1990) Cell biology of von Willebrand factor. Annu Rev Cell Biol 6:217-246
24. Asiyo-Vogel MN, El-Hifnawi ES, Bopp S, Laqua H (1998) The vascular component of proliferative vitreoretinopathy membranes: an immunohistochemical and ultrastructural study. Retina 18:56-61
25. Igarashi Y, Chiba H, Utsumi H et al. (2000) Expression of receptors for glial cell line-derived neurotrophic factor (GDNF) and neurturin in the inner blood-retinal barrier of rats. Cell Struct Funct 25:237-241
26. Harada T, Harada C, Watanabe M et al. (1998) Functions of the two glutamate transporters GLAST and GLT-1 in the retina. Proc Natl Acad Sci USA 95:4663-4666
27. Kelley J, Yerra L, Smith JK, Chi DS (1999) Human endothelium as a source of multifunctional cytokines: molecular regulation and possible role in human disease. J Interferon Cytokine Res 19:91-104
28. Roebuck KA (1999) Oxidant stress regulation of IL-8 and ICAM-1 gene expression: differential activation and binding of the transcription factors AP-1 and NF-kappaB (Review). Int J Mol Med 4:223-230
29. Ohira A, Juan E de Jr (1990) Characterization of glial involvement in proliferative diabetic retinopathy. Ophthalmologica 201:187-195
30. Laterra J, Goldstein GW (1991) Astroglial-induced in vitro angiogenesis: requirements for RNA and protein synthesis. J Neurochem 57:1231-1239
31. Amin RH, Frank RN, Kennedy A, Eliott D, Puklin JE, Abrams GW (1997) Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with nonproliferative diabetic retinopathy. Invest Ophthalmol Vis Sci 38:36-47
32. Behzadian MA, Wang XL, Shabrawey M, Caldwell RB (1998) Effects of hypoxia on glial cell expression of angiogenesis-regulating factors VEGF and TGF-beta. Glia 24:216-225
33. Harada T, Harada C, Nakayama N et al. (2000) Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration. Neuron 26:533-541
34. Harada T, Harada C, Kohsaka S et al. (2002) Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. J Neurosci 22:9228-9236
35. BenEzra D (1978) Neovasculogenic ability of prostaglandins, growth factors, and synthetic chemoattractants. Am J Ophthalmol 86:455-461
36. Masferrer JL, Murphy RC, Pagano PJ, Dunn MW, Laniado-Schwartzman M (1989) Ocular effects of a novel cytochrome P-450-dependent arachidonic acid metabolite. Invest Ophthalmol Vis Sci 30:454-460
37. Heldin CH, Usuki K, Miyazono K (1991) Platelet-derived endothelial cell growth factor. J Cell Biochem 47:208-210
38. Van Antwerp DJ, Martin SJ, Kafri T, Green DR, Verma IM (1996) Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science 274:787-789
39. Huang S, Robinson JB, Deguzman A, Bucana CD, Fidler IJ (2000) Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8. Cancer Res 60:5334-5339
40. Oitzinger W, Hofer-Warbinek R, Schmid JA, Koshelnick Y, Binder BR, Martin R de (2001) Adenovirus-mediated expression of a mutant IkappaB kinase 2 inhibits the response of endothelial cells to inflammatory stimuli. Blood 97:1611-1617