Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases

Analytical Biochemistry

Volumn 319, Issue 1, 2003, Pages 42-48

  Heltweg, Birgit ^a   Dequiedt, Franck ^b   Verdin, Eric ^b   Jung, Manfred ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Histone deacetylase; MAL; Sirtuins; Z MAL

Indexed keywords

DRUG PRODUCTS; ZINC;

CATALYTIC MECHANISMS; DEACETYLASE ACTIVITY; HISTONE DEACETYLASES; INHIBITOR SCREENINGS; REGULATION OF TRANSCRIPTION; SIRTUINS; SMALL MOLECULES; Z-MAL;

SUBSTRATES;

CARBAMIC ACID DERIVATIVE; HISTONE DEACETYLASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG; ZINC; [5 ACETYLAMINO 1 (4 METHYL 2 OXO 2H CHROMEN 7 YLCARBAMOYL)PENTYL]CARBAMIC ACID BENZYL ESTER;

ARTICLE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL;

EID: 0038003142     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(03)00276-8     Document Type: Article

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