Synthesis and biological activity of 2'-fluoro- darabinofuranosylpyrazolo[3,4-d]pyrimidine nucleosides

Helvetica Chimica Acta

Volumn 82, Issue 12, 1999, Pages 2240-2245

  Shortnacy Fowler, Anita T ^a   Tiwari, Kamal N ^a   Montgomery, John A ^a   Buckheit Jr , Robert W ^a   Secrist III, John A ^a   Seela, Frank ^b  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; NUCLEOSIDE; PYRIMIDINE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; DEAMINATION; HEPATITIS B VIRUS; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 8; NONHUMAN; SYNTHESIS; TUMOR CELL LINE;

EID: 0033403405     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2675(19991215)82:12<2240::AID-HLCA2240>3.0.CO;2-2     Document Type: Article

References (20)

1. J. A. Montgomery, Antimetabolites in 'Cancer Chemotherapeutic Agents,' Ed. W. Foye, American Chemical Society, Washington, DC, 1995, pp. 47-109.
2. R. W. Brockman, F. M. Schabel, Jr., J. A. Montgomery, Biochem. Pharmacol. 1977, 26, 2193.
3. S. J. Wright, L. E. Robertson, S. O'Brien, W. Plunkett, M. J. Kealing, Blood Rev. 1994, 8, 125.
4. D. A. Carson, D. B. Wasson, J. Kaye, B. Ullman, D. W. Martin, Jr., R. K. Robins, J. A. Montgomery, Proc. Natl. Acad. Sci. U.S.A. 1980, 77, 6065.
5. J. A. Montgomery, A. Shortnacy-Fowler, S. D. Clayton, J. M. Riordan, J. A. Secrist, III, J. Med. Chem. 1992, 35, 397.
6. W. B. Parker, S. C. Shaddix, L. M. Rose, D. S. Shewach, L. W. Hertel, J. A. Secrist, III, J. A. Montgomery, L. L. Bennett, Jr., Mol. Pharmacol. 1999, 55, 515.
7. F. Seela, H. Winter, M. Möller, Helv. Chim. Acta 1993, 76, 1450; F. Seela, H. Steker, ibid 1985, 68, 563.
8. F. Seela, H. Winter, M. Möller, Helv. Chim. Acta 1993, 76, 1450; F. Seela, H. Steker, ibid 1985, 68, 563.
9. F. Seela, W. Bourgeois, H. Winter, Nuclosides Nucleotides 1991, 10, 713.
10. H. E. Skipper, R. K. Robins, J. R. Thomson, C. C. Cheng, R. W. Brockman, F. M. Schabel, Jr., Cancer Res. 1957, 17, 579.
11. R. K. Shaw, R. N. Shulman, J. D. Davidson, D. P. Ball, E. J. Frei, III, Cancer 1960, 13, 482.
12. F. Seela, H.-D. Winkeler, J. Org. Chem. 1983, 48, 3119.
13. Z. Kazimierczuk, H. B. Cottam, G. R. Revankar, R. K. Robins, J. Am. Chem. Soc. 1984, 106, 6379.
14. R. K. Robins, J. Am. Chem. Soc. 1956, 78, 784.
15. C. H. Tann, P. R. Brodfuehrer, S. P. Brundidge, C. Sapino, Jr., H. G. Howell, J. Org. Chem. 1985, 50, 3644.
16. O. Jungmann, W. Pfleiderer, Tetrahedron Lett. 1996, 37, 8355.
17. J. A. Secrist, III, K. N. Tiwari, A. T. Shortnacy-Fowler, L. Messini, J. M. Riordan, J. A. Montgomery, S. C. Meyers, S. E. Ealick, J. Med. Chem. 1998, 41, 3865.
18. W. A. Tatarowicz, N. S. Lurain, K. D. Thompson, J. Virol. Methods 1991, 35, 207; B. F. Korba, J. L. Gerin, Antiviral Res. 1992, 19, 55.
19. W. A. Tatarowicz, N. S. Lurain, K. D. Thompson, J. Virol. Methods 1991, 35, 207; B. F. Korba, J. L. Gerin, Antiviral Res. 1992, 19, 55.
20. R. H. Shoemaker, S. M. Halliday, T. M. Fletcher, R. W. Buckheit, Jr., E. A. Sausville, submitted.