Enhancement of nucleoside cytotoxicity through nucleotide prodrugs

Journal of Medicinal Chemistry

Volumn 45, Issue 20, 2002, Pages 4505-4512

  Rose, Jerry D ^a   Parker, William B ^a   Someya, Hitoshi ^a   Shaddix, Sue C ^a   Montgomery, John A ^a   Secrist III, John A ^a  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 AZA 2' DEOXYADENOSINE; 8 BROMO 2' DEOXYADENOSINE; ANTINEOPLASTIC AGENT; NUCLEOTIDE DERIVATIVE; PHOSPHOTRANSFERASE; PRODRUG; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVATION; DRUG INACTIVATION; DRUG MECHANISM; ENZYME INACTIVATION; HUMAN; HUMAN CELL;

ADENOSINE MONOPHOSPHATE; ANTINEOPLASTIC AGENTS; DEOXYADENOSINES; DNA; DNA POLYMERASE I; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; PRODRUGS; RNA; TUMOR CELLS, CULTURED; URIDINE KINASE;

EID: 0037179624     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020107s     Document Type: Article

References (20)

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